Title: Pet-friendly Vacations in Northeast Missouri 2026 | Expedia.ca ![](https://images.trvl-media.com/place/10540/802bf5d7-a3f6-4e16-b933-40ae5b4ec325.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Northeast Missouri Pet-friendly Vacations ## Book a Hotel + Flight or Car together to unlock savings Photo by Andrew Hershfeld - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Pet-friendly Hotels in Northeast Missouri ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 421 N 8th St St. Louis MO - 13 min walk from St. Louis Union Station Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ... 8.6/10 Excellent! (1,179 reviews) Great accommodations and I loved the pet friendly environment! Looking forward to trying more of the in-room dining options next time. Reviewed on Dec 30, 2025 [](https://expedia.ca/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 21C Museum Hotel St Louis 1528 Locust street St. Louis MO - 5 min walk from St. Louis Union Station Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ... 9/10 Wonderful! (1,533 reviews) Great staff and very clean room. Reviewed on Jan 5, 2026 [](https://expedia.ca/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Home2 Suites by Hilton St. Louis Downtown 1221 Locus Street St. Louis MO - 8 min walk from St. Louis Union Station Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, valet parking (surcharge), and a 24-hour front desk. Our guests praise the helpful ... 8/10 Very Good! (628 reviews) Actual ceramic plates and metal silverware!!! Side Note: The roatary toaster is the bomb! 😃 Reviewed on Jan 2, 2026 [](https://expedia.ca/St-Louis-Hotels-Home2-Suites-St-Louis-Downtown.h76510729.Hotel-Information) [See all 2,802 properties in Northeast Missouri](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6058818) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Northeast Missouri ](https://expedia.ca/Cheap-Flights-To-Northeast-Missouri.d6058818.Travel-Guide-Flights)[ Northeast Missouri Hotels ](https://expedia.ca/Northeast-Missouri-Hotels.d6058818.Travel-Guide-Hotels)[ Northeast Missouri Vacation Rentals ](https://expedia.ca/Northeast-Missouri-Vacation-Rentals.d6058818.Travel-Guide-VacationRentals)[ Northeast Missouri Car Rentals ](https://expedia.ca/Car-Rentals-In-Northeast-Missouri.d6058818.Car-Rental-Guide)[ Northeast Missouri Vacations ](https://expedia.ca/Northeast-Missouri.d6058818.Destination-Travel-Guides)[ Things to do in Northeast Missouri ](https://expedia.ca/Things-To-Do-In-Northeast-Missouri.d6058818.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app