Title: Adventure Vacations in Mesopotamia 2025/2026 | Expedia.ca ![](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mesopotamia Adventure Vacations ## Book a Hotel + Flight or Car together to unlock savings Stay added Flight added Car - Economy - Premium economy - Business class - First class Leaving from Going to Dates Travellers ## Room 1 Adults ChildrenAges 2 to 17 InfantsYounger than 2 I only need accommodation for part of my trip - ## Plan, book, travel with confidence ### Better together Save up to CA $1,096 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Plan, book, and manage your trip all in one place ## Adventure Hotels in Mesopotamia ![Iguazu Grand Resort Spa & Casino](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Iguazu Grand Resort Spa & Casino Route 12 Km 1640, Puerto Iguazú, Misiones - 17 hours drive from Termas de Federacion Stay at this 5-star luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ... 9/10 Wonderful! (572 reviews) Spacious room, great amenities Reviewed on Oct 21, 2025 [](https://expedia.ca/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information) ![Hotel das Cataratas, A Belmond Hotel, Iguassu Falls](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/7373d519_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR - 17 hours drive from Termas de Federacion Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ... 9.8/10 Exceptional! (1,024 reviews) It has the feel of a grand old resort (and I don't mean "old" in any sort of pejorative sense at all; it felt like what I imagine going on safari in a luxury lodge would have felt like in the 1800s). The facilities and the location are, for an Iguacu vacation, absolutely second to none. The staff ... Reviewed on Oct 26, 2025 [](https://expedia.ca/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information) ![Gran Melia Iguazú](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/2ab2ddf5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gran Melia Iguazú Parque Nacional Iguazu, Puerto Iguazú, Misiones - 17 hours drive from Termas de Federacion Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition ... 9/10 Wonderful! (1,001 reviews) Excellent base to explore the Iguazu park and falls. Reviewed on Oct 23, 2025 [](https://expedia.ca/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information) [See all 492 properties in Mesopotamia](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6208836) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Hotels](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Mesopotamia Vacation Rentals](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacations](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAMgAQAAAADzCzvFAAAFLklEQVR4Xu3aMXLjOBBGYUxNoHCPoKPwaOTRdBQeYUIFrsG6fzTRIMTxVgezgfxeYqoF4GNGS3ap/0NlHvyNQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZJqQD7K1P0Y/aj1UW6fiz9H6pdNl/osn9t3u17baGyNk0EKyLwMpLXGySAFZF4G0lrj5HdF1nilE8Nd2nBv20fEN/6yW+mdzwIBAQGxQBSIAun5WnXryNrefNjUF27FH/sa7fbDEY3OGy0QEBD7AQJSQEC8rxGl7WNbW7PYdbsEAbFAxra2ZrHrdgkCYoGMbW3NYtftEmREdOLTz7P+qb8H5GdbBaJA/FhbFJcgICCP9jYIiJqRqK9117d7QuT2VT+GzSAgFQRkfgOkBQJSZ+TcuP1Rbif3YjS1xskgF6OpNU4GuRhNrXEyyMVoao2TQS5GU2ucDHIxmlrjZJCL0dQaJw/IRaOrE/v2333uyFeBgFwEMgUCchHI1Psi/qjWidpuX2dXe6D7idX+wKxvuC9a7G2/XvuZICAtkNZib/v12s8EAWmBtBZ726/XfubbIr59aa/2Y61OvA0j/4hd5v+4rval97DRAwGpINoIAgIC0hoQPdC9zxNLudvU3Z7+mUs9musb4+7OqzSJSxAQkMVenldpEpcgICCLvTyv0iQu3wzR5+n+qNZaPdBVd/VAf9h6f8duRT3nW7FAQEDaCAQEpAVyRtZ6+Q23nt5ylZ04jSz9JnCzK7+7HggIyBEICAiINa6yHCm2fT8u9UCXW9r2uJV+4vk3Ad1wD0SBgICAgIAck7jUG+NanWgPdPVsB8eJ7t7b2y8bh0BAQNrbLxuHQEBA2tsvG4feFend+nRrg8Wu/UQb6US592HjcrqVHggICAgIyNYGi12DnJG1+hfVntb60ztOHH8TGDo2znMQEJAIBGQKBETpu+vlePVhr8aP2B3RqqeduNv12fVRDwREgYBUEJAKogZE2/Wo1vZ+onrYwLbHY99Haiv6ly99NrcfWtUDAQGxQEBAKog3IOpPz3idaG6sUuZ6h9tX9UCOQEBAQI79HsjRt0a2oke1P+PVWvXY19PbT/TR8rpR2euP/suBBQJSQWKjstcgIBUERG+UAelz/zwdSE8jZcgYCEgFAQFpgfQ5SLw6I2s7sRpSyv0YHcXanq3ydHcaffENN8hxCQICAqJJXIIcl98W8Qf6uachu23vD3TdilqrI+Pd9UCOEQgIyBhIBQFxxNfaOy9ra0f012RHtGrMVhUQC6QHAqJ3QEB6IF8V2xc7cUDUbb6V/svB+e5AQC4CAQGxQEDiRO9u0634A/286hh1xD+bez+HHSAgICBHd5tuBSQCAdHa6Ixouz/ja/W/Od/sererte3RKs9HFogCiUCOfGSBKJAI5MhH1vsisd0Qd/Wl99Pmd1u4tTV99NFeqxfXAikgICAgIBUkTv5PxFu0+LPxGV/6Y9//5evRhv3uPJAjEAukDUEWLS4gPRCQPyL3tlSr/Bkvdyv6IF5tdJwXgWgEAlJAQF4C0Qgk8hNt+3hitAyLt2HUb6UHolG0DSMQEA9Eo2gbRiAg3rsi5+42tQ/P+obbFseo2ufpm/3Yban9chDP+N0e+0MgFWQyQEBAPJD67ZG/F0gqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSvQ/yL/hVEhnLDbsTAAAAAElFTkSuQmCC)