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Adventure Hotels in Mesopotamia

Iguazu Grand Resort Spa & Casino

Route 12 Km 1640 Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

9/10 Wonderful! (633 reviews)

The staff and amenities were amazing. The rooms large and spacious.

Reviewed on Mar 15, 2026

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Book a stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...

9.8/10 Exceptional! (1,003 reviews)

You go here for the views of course. The common areas are beautiful. The rooms are 3 star - not 5. They are worse than a premier inn or a Hampton room - small, shabby and dated. The amenities are not as you’d expect of a 5 star. Not even a plug socket on one side of the bed. The pictures are fixed ...

Reviewed on Mar 13, 2026

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

9.2/10 Wonderful! (1,002 reviews)

Wonderful stay in the park Hike to Iguazu falls from hotel Amazing breakfast and bbq Pool was much needed with poolside service

Reviewed on Mar 15, 2026

See all 513 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.