Title: Adventure Vacations in Mesopotamia 2026 | Expedia.ca ![](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mesopotamia Adventure Vacations ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Flight and Adventure hotel deals in Mesopotamia Price found within the past 48 hours. Click for updated prices. ![Posada Puerto Bemberg](https://images.trvl-media.com/lodging/3000000/2300000/2293100/2293030/04d72c9e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Posada Puerto Bemberg CA $845 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.8/10 Exceptional! (15 reviews) The setting was excellent and location was very special but the food was very average. Reviewed on Feb 24, 2020 ![Gran Melia Iguazú](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/596c9ef3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Gran Melia Iguazú CA $1,694 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.2/10 Wonderful! (1,002 reviews) Fantastic view from waterfall facing room, Hotel was immaculate & park access was a definite plus, made seeing Iguazu Falls an absolute pleasure. Reviewed on Dec 29, 2025 ![Loi Suites Iguazú Hotel](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/f6b00076_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Loi Suites Iguazú Hotel CA $1,013 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.2/10 Wonderful! (1,001 reviews) This hotel beautifully incorporates nature into its design, making guests feel seamlessly immersed in the Iguazú jungle, almost like natives of the environment. The pools are wonderful, and the staff throughout the property are warm and welcoming, making this a truly worthwhile stay. The only area for improvement would be the front desk staff, who did not seem as friendly or inviting as the rest of the team. Reviewed on Dec 29, 2025 ![Iguazu Grand Resort Spa & Casino](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Iguazu Grand Resort Spa & Casino CA $1,049 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9/10 Wonderful! (581 reviews) Spacious rooms, grand looking interiors. Reviewed on Dec 26, 2025 ![Amérian Portal del Iguazú Hotel](https://images.trvl-media.com/lodging/3000000/2240000/2239000/2238924/00cf9fa2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Amérian Portal del Iguazú Hotel CA $914 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 8.6/10 Excellent! (357 reviews) The hotel location offers beautiful views of the three countries. There are several restaurants overlooking the rivers close to the Tres Fronteras that are easy to walk to. The room was comfortable but a bit beat up in places. The staff was helpful and friendly. Reviewed on Dec 6, 2025 Don't see what you're looking for? See all available trips from Columbus to Mesopotamia [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-30/2026-02-06/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=AOL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Adventure holidays in Mesopotamia Price found within the past 48 hours. Click for updated prices. ![Loi Suites Iguazú Hotel](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/f6b00076_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Loi Suites Iguazú Hotel CA $1,013 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.2/10 Wonderful! (1,001 reviews) This hotel beautifully incorporates nature into its design, making guests feel seamlessly immersed in the Iguazú jungle, almost like natives of the environment. The pools are wonderful, and the staff throughout the property are warm and welcoming, making this a truly worthwhile stay. The only area for improvement would be the front desk staff, who did not seem as friendly or inviting as the rest of the team. Reviewed on Dec 29, 2025 ![Gran Melia Iguazú](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/596c9ef3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Gran Melia Iguazú CA $1,694 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.2/10 Wonderful! (1,002 reviews) Fantastic view from waterfall facing room, Hotel was immaculate & park access was a definite plus, made seeing Iguazu Falls an absolute pleasure. Reviewed on Dec 29, 2025 ![Iguazu Grand Resort Spa & Casino](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Iguazu Grand Resort Spa & Casino CA $1,049 per person Mar 18 - Mar 20 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9/10 Wonderful! (581 reviews) Spacious rooms, grand looking interiors. Reviewed on Dec 26, 2025 Don't see what you're looking for? See all available trips from Columbus to Mesopotamia [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-30/2026-02-06/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=AOL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Adventure holidays in Mesopotamia Price found within the past 48 hours. Click for updated prices. ![Falls Iguazú Hotel & Spa](https://images.trvl-media.com/lodging/17000000/16830000/16828100/16828044/2e727a7b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Falls Iguazú Hotel & Spa CA $1,042 per person Feb 25 - Feb 28 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.2/10 Wonderful! (455 reviews) Hotel was clean great service very little English spoken! Reviewed on Dec 3, 2025 ![Gran Melia Iguazú](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/596c9ef3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Gran Melia Iguazú CA $2,161 per person Feb 25 - Feb 28 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.2/10 Wonderful! (1,002 reviews) Fantastic view from waterfall facing room, Hotel was immaculate & park access was a definite plus, made seeing Iguazu Falls an absolute pleasure. Reviewed on Dec 29, 2025 ![Loi Suites Iguazú Hotel](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/f6b00076_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Loi Suites Iguazú Hotel CA $1,196 per person Feb 25 - Feb 28 found 1 day ago Roundtrip flight included Buenos Aires (BUE) to Iguazu (IGR) 9.2/10 Wonderful! (1,001 reviews) This hotel beautifully incorporates nature into its design, making guests feel seamlessly immersed in the Iguazú jungle, almost like natives of the environment. The pools are wonderful, and the staff throughout the property are warm and welcoming, making this a truly worthwhile stay. The only area for improvement would be the front desk staff, who did not seem as friendly or inviting as the rest of the team. Reviewed on Dec 29, 2025 Don't see what you're looking for? See all available trips from Columbus to Mesopotamia [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-30/2026-02-06/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=AOL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Adventure Hotels in Mesopotamia ![Iguazu Grand Resort Spa & Casino](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Iguazu Grand Resort Spa & Casino Route 12 Km 1640 Puerto Iguazú Misiones - 17 hours drive from Termas de Federacion Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ... 9/10 Wonderful! (593 reviews) Spacious rooms, grand looking interiors. Reviewed on Dec 26, 2025 [](https://expedia.ca/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information) ![Hotel das Cataratas, A Belmond Hotel, Iguassu Falls](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/7373d519_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls Rodovia Br 469 Km 32 Foz do Iguaçu PR - 17 hours drive from Termas de Federacion Book a stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ... 9.8/10 Exceptional! (1,003 reviews) Excellent service, courteous and caring staff! Luxury redefined, and why it is worth staying at a Belmond! The only thing that was less than outstanding, was the dinner buffet - limited vegetarian options Reviewed on Dec 23, 2025 [](https://expedia.ca/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information) ![Gran Melia Iguazú](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/596c9ef3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gran Melia Iguazú Parque Nacional Iguazu Puerto Iguazú Misiones - 17 hours drive from Termas de Federacion Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ... 9.2/10 Wonderful! (1,000 reviews) Incredible views, fantastic breakfast, lounge and infinity pool. Hotel employees were very helpful. Overall, hotel was nice, but rooms and hallways show age. Reviewed on Dec 20, 2025 [](https://expedia.ca/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information) [See all 490 properties in Mesopotamia](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6208836) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Mesopotamia ](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[ Mesopotamia Hotels ](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[ Mesopotamia Vacation Rentals ](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[ Mesopotamia Car Rentals ](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[ Mesopotamia Vacations ](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app