Find hotels in Mesopotamia from CA $55

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mesopotamia hotels

Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
3.0 star property
Concordia
9.2 out of 10, Wonderful, (7 reviews)
"Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación "
United States
Catalina
The price is CA $135
CA $135 total
Feb 22 - Feb 23
Mayim Hotel Termal & SPA

Hathor Concordia

Hathor Concordia
3.0 star property
Concordia
8.6 out of 10, Excellent, (369 reviews)
"AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road."
United States
Patrick
Hathor Concordia

Turismo Hotel Casino

Turismo Hotel Casino
2.5 star property
Corrientes
8.0 out of 10, Very good, (4 reviews)
"Boa infraestrutura, e localização!"
Brazil
D. Omar
The price is CA $153
CA $153 total
Mar 1 - Mar 2
Turismo Hotel Casino

Agustín 1 Apart

Agustín 1 Apart
4.0 star property
Parana
9.0 out of 10, Wonderful, (4 reviews)
"Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável."
Brazil
Jose rodrigo kallas
The price is CA $74
CA $74 total
Feb 25 - Feb 26
Agustín 1 Apart

Intersur Colon

Intersur Colon
3.0 star property
Colón
8.8 out of 10, Excellent, (6 reviews)
"Is ok "
United States
Carla
The price is CA $131
CA $131 total
Mar 18 - Mar 19
Intersur Colon

Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.0 out of 10, Wonderful, (32 reviews)
"Great location and friendly, accommodating staff. "
United States
Michael
The price is CA $126
CA $126 total
Feb 23 - Feb 24
Maran Suites & Towers - Hotel & Spa

Marriott Corrientes Hotel

Marriott Corrientes Hotel
4.5 star property
Corrientes
10.0 out of 10, Exceptional, (22 reviews)
"Fantastic stay. Room was immaculate and hotel staff were very friendly and helpful. Great pool and beds were super comfortable."
Australia
Marcus
The price is CA $195
CA $195 total
Feb 28 - Mar 1
Marriott Corrientes Hotel

La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
4.0 star property
Corrientes
9.2 out of 10, Wonderful, (68 reviews)
"Todo excelente "
Mexico
Arturo Oscar
La Alondra Casa De Huéspedes

O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú
2.5 star property
Gualeguaychú
7.6 out of 10, Good, (73 reviews)
"Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. "
United States
Esteban
The price is CA $61
CA $61 total
Mar 1 - Mar 2
O2 Hotel Gualeguaychú

Hotel Rio

Hotel Rio
3.0 star property
Chajarí
8.8 out of 10, Excellent, (11 reviews)
"Lindo hotel, moderno, limpio, buena atencion, sumaria opciones saladas en el desayuno, como huevos revueltos."
Argentina
SANTIAGO
The price is CA $108
CA $108 total
Mar 3 - Mar 4
Hotel Rio

Donsuites Apart Hotel

Donsuites Apart Hotel
3.0 star property
Corrientes
8.6 out of 10, Excellent, (106 reviews)
"Loved this place, super clean, and the staff were very nice and helpful😍"
United States
Nora
The price is CA $86
CA $86 total
Feb 23 - Feb 24
Donsuites Apart Hotel

Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
3.5 star property
Bella Vista
8.6 out of 10, Excellent, (4 reviews)
"Pessoal da recepção excelente acolhimento. Hotel bonito, falta manutenção em certos lugares. Quarto ótimo, cama com colchão selado e barulho nos ares condicionados. Café da manhã deixa a desejar. Restaurante muito bonito. "
Brazil
Anonymous traveller
Rio Arriba Suites Apartments y Resto

Casa del Árbol Hostel

Casa del Árbol Hostel
3.0 star property
Concepción del Uruguay
8.4 out of 10, Very good, (8 reviews)
"El lugar es divino, la onda de Guadalupe la dueña del lugar"
Argentina
Sebastián
The price is CA $53
CA $53 total
Feb 23 - Feb 24
Casa del Árbol Hostel

Urban Hotel

Urban Hotel
3.0 star property
Federacion
6.0 out of 10, (2 reviews)
"La habitación muy bien y el personal excelente "
Costa Rica
Carlos alberto
Urban Hotel

Club Valle Termal Resort

Club Valle Termal Resort
3.0 star property
Federacion
9.2 out of 10, Wonderful, (94 reviews)
"La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto."
United States
Fernando
The price is CA $93
CA $93 total
Feb 26 - Feb 27
Club Valle Termal Resort

Complejo La Loma

Complejo La Loma
3.0 star property
Federacion
8.0 out of 10, Very good, (5 reviews)
"Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple...
Canada
Logan
Complejo La Loma

Bungalows Mexico

Bungalows Mexico
2.5 star property
Concepción del Uruguay
8.8 out of 10, Excellent, (12 reviews)
"Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. "
Brazil
Eduardo
The price is CA $70
CA $70 total
Mar 12 - Mar 13
Bungalows Mexico

Totoras Apart Federacion

Totoras Apart Federacion
2.5 star property
Federacion
7.4 out of 10, Good, (27 reviews)
"Todo perfecto!!! "
Mexico
Gabriel
Totoras Apart Federacion

La Casona de Susana

La Casona de Susana
3.0 star property
Colon
7.4 out of 10, Good, (25 reviews)
"La propietaria respeta el precio acordado. En verano si usás más de 8 horas por día el aire acondicionado te cobran un plus."
Argentina
Marlene Ruth
The price is CA $55
CA $55 total
Mar 13 - Mar 14
La Casona de Susana

Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
3.0 star property
Federacion
8.6 out of 10, Excellent, (13 reviews)
"good for a 1 night stay"
Canada
Chase
Hotel y Spa Termas del Este
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

Vacation Rentals in Mesopotamia

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mesopotamia attractions

Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

Iguazu Falls featuring a cascade

Top Mesopotamia Hotel Reviews

More cheap stays in Mesopotamia

Hotels in Mesopotamia with star rating

Find out more about Mesopotamia

Top reasons to visit Mesopotamia

  • Scenic National Parks: Explore stunning national parks with breathtaking mountain views and lush landscapes, perfect for nature lovers.
  • Outdoor Adventures: Engage in exciting activities like hiking, birdwatching, and water parks, catering to both thrill-seekers and families.
  • Charming Neighbourhoods: Stroll through romantic neighbourhoods like Bahcamatiate and Midyat, offering a delightful atmosphere.
  • Family-Friendly Activities: Enjoy a variety of attractions designed for family vacations that ensure fun for all ages.
  • Comfortable Accommodations: Stay in diverse hotel options, from cozy retreats to luxurious facilities, ensuring a memorable experience.

Find great hotels near Mesopotamia

Discover a variety of hotel accommodations in Mesopotamia, Argentina, designed for families seeking unforgettable vacations. From cozy retreats to top-notch star-rated facilities, you’ll find options that suit every traveller's needs. Whether you're looking for the best hotels or a tranquil stay at the Calma Hotel, Mesopotamia offers a welcoming atmosphere and essential amenities to make your stay memorable.

  • El Tránsito Hotel Boutique: Nestled 29.0km from Mesopotamia, El Tránsito Hotel Boutique offers a charming family-friendly atmosphere perfect for a memorable vacation. This 3.5-star hotel is designed with families in mind, featuring an Arcade Game Room, a children's pool, and complimentary cribs. Guests appreciate the inviting ambiance, attentive service, and amenities tailored for kids, ensuring a delightful stay for both parents and children. Embrace the warmth of Argentinian hospitality while enjoying a peaceful retreat at this lovely boutique hotel.

Where to stay near Mesopotamia

Mesopotamia, Argentina, offers an exciting blend of adventure and relaxation for every family. Discover the breathtaking mountain views while exploring the scenic trails and lush landscapes nearby. The charming neighborhoods, like Bahcamatiate and Midyat, provide a romantic backdrop for leisurely strolls. Whether you're hiking or enjoying outdoor activities, the region promises an unforgettable experience that combines natural beauty with family-friendly fun.

  • Mercedes: Nestled 49.9km from Mesopotamia, Mercedes is a vibrant city that offers a delightful mix of outdoor adventures and family-friendly experiences. Visitors are drawn to its national state park, water park, and theme park, making it an ideal destination for thrill-seekers and nature lovers alike. The city sees a surge in tourist activity during July and the festive season from December to January, but it's a year-round destination for those seeking adventure. Whether you're swinging a club at a local golf course or splashing around at the water park, Mercedes promises an exhilarating getaway.
  • Concepción: Located 35.4km from Mesopotamia, Concepción is a picturesque city perfect for outdoor enthusiasts and those seeking scenic beauty. The city's allure peaks in April, July, and September, attracting visitors keen on exploring its national state park and surrounding natural parks. With ample opportunities for hiking and sightseeing, Concepción invites you to immerse yourself in its stunning landscapes. The relatively stable visitor numbers throughout the year mean you can enjoy a quieter experience while still indulging in its natural charm.
  • Uguay: Just 27.4km from Mesopotamia, Uguay is a quaint village that embodies the essence of tranquil rural life. Known for its seasonal visitor influx, peaking in January, March, and November, Uguay is a haven for nature lovers. The nearby natural parks provide a serene backdrop for leisurely hikes and picnics amidst stunning landscapes. If you’re looking for a slow-paced escape from the hustle and bustle of city life, Uguay offers a peaceful retreat that celebrates the beauty of the great outdoors.

Things to do in Mesopotamia

Mesopotamia, Argentina, offers a variety of activities perfect for family and adventure vacations. Visitors can enjoy exciting attractions such as water parks, birdwatching, and scenic hiking trails. This diverse region ensures a memorable experience for tourists seeking both relaxation and outdoor fun.

Shopping

In Mesopotamia, you can explore shopping at the Shopping del Sol, featuring popular brands and local boutiques. For a more traditional experience, visit the Mercado Municipal, where you’ll find unique handicrafts and delicious regional foods, perfect for gifts and souvenirs.

Recreation

Experience a tranquil stay at Termas de Río Hondo, where you can indulge in natural thermal baths and rejuvenating spa treatments. For recreation, explore the lush landscapes on horseback or enjoy leisurely walks along the scenic riverside, immersing yourself in the serene beauty of Mesopotamia.

Adventure

Explore the stunning Ibera Wetlands, home to diverse wildlife, by canoe or kayak. Experience thrilling hikes through lush landscapes at Quebrada de Humahuaca, where you can marvel at vibrant rock formations and learn about the region's rich cultural heritage.

Nightlife

The nightlife in Mesopotamia, Argentina, is vibrant and diverse. Enjoy a lively evening at local bars like El Club de la Cerveza for craft brews, or dance the night away at La Fiesta, where live music creates an electrifying atmosphere. Experience the unique culture and warm hospitality of the region.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesopotamia

When planning your trip to Mesopotamia, Argentina, consider visiting during the off-peak months for lower prices, avoiding July, August, and December. Book accommodations about a month in advance or check Expedia's last-minute deals for savings. Tuesdays are the best days for cheaper stays, while Mondays tend to be pricier. Use Expedia’s search tools to filter for budget-friendly and eco-certified options, and consider bundling your hotel, flights, and activities for additional discounts. Look out for free activities in the area to maximize your enjoyment without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mesopotamia are , where the prices are slightly lower. This is in comparison to July to August and December, where prices are slightly higher.
  • The best time to book a hotel: The cheapest time to book a hotel around Mesopotamia is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, preferred location, and the type of hotel you desire. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly accommodations currently available. To discover the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save some money by combining your hotel reservations in Mesopotamia with your flights and activities through an Expedia package.

Find the best attractions near Mesopotamia

Mesopotamia, Argentina, offers a fantastic blend of entertainment, adventure, and family-friendly activities. Explore stunning national parks and enjoy the breathtaking scenery while engaging in outdoor experiences that cater to thrill-seekers and nature lovers alike. With a variety of points of interest, your vacation in Mesopotamia promises unforgettable adventures for all types of travelers.

  • Portal Carambola: Located 22.5km from Mesopotamia, this national park offers thrilling adventures amidst stunning scenery and a vibrant outdoor atmosphere, perfect for nature enthusiasts seeking unique experiences in Argentina.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.700000000000003°C)Light RainSunnyModerately HighAverage
February77.7°F (25.4°C)Light RainMostly Sunny
March72.9°F (22.700000000000003°C)Light RainMostly SunnyModerately HighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageAverage
November72.3°F (22.4°C)Light RainSunnyModerately HighAverage
December77.0°F (25.0°C)Light RainSunnyAverageSlightly High

The nearest major airports for your trip to Mesopotamia

To reach Mesopotamia, Argentina, you can fly into three major airports. Posadas (PSS-Libertador General Jose de San Martin) is 222.1km away, with nearby hotels such as La Mision Posadas Hotel and Continental Posadas Hotel both offering airport transportation services. Resistencia (RES-Resistencia Intl.) is located 181.9km from Mesopotamia, featuring hotels like Gala Hotel y Convenciones, which also provides transport. Corrientes (CNQ-Corrientes Intl.) is the closest at 164.2km, with options including La Alondra Casa De Huéspedes and Turismo Hotel Casino, both offering airport shuttle services. Each airport provides convenient access to the charming attractions of Mesopotamia.