Mesopotamia Vacation Packages

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Your Mesopotamia Vacation

When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.

Top Mesopotamia Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Mérit Parque Leloir by Amérian

Mérit Parque Leloir by Amérian

3 out of 5
per person
Aug 17 - Aug 24
found 11 hours ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (BUE)
9.8/10 Exceptional! (11 reviews)
Todo muy bien, excepto que falta cable para ver canales del pais

Reviewed on Jun. 22, 2025

Estancia Villa Maria

Estancia Villa Maria

3.5 out of 5
per person
Aug 24 - Aug 30
found 7 hours ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (BUE)
9.4/10 Exceptional! (93 reviews)
Gorgeous, peaceful property and the staff was very friendly and attentive. We enjoyed our quiet time here at the end of a whirlwind trip.

Reviewed on Apr. 29, 2025

Four Seasons Hotel Buenos Aires

Four Seasons Hotel Buenos Aires

5 out of 5
Buenos Aires Central Business District
Save 100% on your flight
per person
Sep 24 - Sep 30
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (BUE)
9.4/10 Exceptional! (254 reviews)
This is an amazing property. We enjoyed our stay. The staff are very attentive and cordial. We would stay at the Four Seasons Buenos Aires again.

Reviewed on Jun. 24, 2025

SLS Buenos Aires Puerto Madero

SLS Buenos Aires Puerto Madero

4 out of 5
Puerto Madero
Save 100% on your flight
per person
Sep 24 - Sep 30
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (BUE)
9.6/10 Exceptional! (241 reviews)
Excellent stay, beautiful property, amazing location, and staff was very attentive as well as welcoming.

Reviewed on May 18, 2025

Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
El Centro
Save 100% on your flight
per person
Sep 24 - Sep 30
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (BUE)
8.8/10 Excellent! (1,000 reviews)
Bellmen probably treated people base on the race.

Reviewed on Mar. 31, 2025

Ready to book your vacation to Mesopotamia?

 

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Mesopotamia Hotel Deals

O2 Hotel Gualeguaychú
O2 Hotel Gualeguaychú
2.5 out of 5
115 3 de Febrero, Gualeguaychú, Entre Ríos
Fully refundableReserve now, pay when you stay
The price is CA $49 per night from Jul 13 to Jul 14
CA $49
CA $49 total
Jul 13 - Jul 14
7.4/10 Good! (58 reviews)
"Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice."

Reviewed on Jan. 2, 2025

O2 Hotel Gualeguaychú
Hathor Concordia
Hathor Concordia
3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
Fully refundableReserve now, pay when you stay
The price is CA $66 per night from Aug 4 to Aug 5
CA $66
CA $81 total
Aug 4 - Aug 5
8.6/10 Excellent! (345 reviews)
"Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful."

Reviewed on Dec. 31, 2024

Hathor Concordia
Hotel La Bahia
Hotel La Bahia
2.5 out of 5
San Lorenzo 553, Federacion, Entre Rios (province)
Get rates
Hotel La Bahia
See all 475 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Discover the most popular places to visit in Mesopotamia

El Palmar National Park

El Palmar National Park

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

El Palmar National Park

Frequently asked questions

How much does a Mesopotamia vacation package cost?
Maybe less than you might think --- from only CA $653, actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia vacation package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travelers.
How far in advance should I book my Mesopotamia vacation?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travelers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including vacation rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia vacation package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia vacation package?
Don't worry if you're rethinking your Mesopotamia vacation package --- you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realize life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.