Mesopotamia Vacation Packages

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Your Mesopotamia Vacation

When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.

Top Mesopotamia Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Bulnes Eco Suites

Bulnes Eco Suites

4 out of 5
Palermo
Price was CA $2,024, price is now CA $1,512 per person
CA $1,512
per person
Aug 6 - Aug 11
found 21 hours ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (EZE)
9.4/10 Exceptional! (1,251 reviews)
Great location, comfy room and very fair price

Reviewed on Jun 13, 2026

Alvear Icon Hotel

Alvear Icon Hotel

5 out of 5
Puerto Madero
Price was CA $2,624, price is now CA $2,085 per person
CA $2,085
per person
Aug 6 - Aug 11
found 21 hours ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (EZE)
9.6/10 Exceptional! (594 reviews)
Todo excelente. Solo q esta en medio de la nada. No hay comercio. Restaurantes. Cafe’s en rededores pero el hotel muy muy bueno

Reviewed on Jun 11, 2026

Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
El Centro
Price was CA $1,972, price is now CA $1,574 per person
CA $1,574
per person
Aug 6 - Aug 11
found 21 hours ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (EZE)
8.8/10 Excellent! (1,001 reviews)
Great location, walkable distance to Puerto Madero areas and Buquebus

Reviewed on May 9, 2026

Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite

4.5 out of 5
Puerto Madero
Price was CA $2,208, price is now CA $1,806 per person
CA $1,806
per person
Aug 6 - Aug 11
found 21 hours ago
Roundtrip flight included
Toronto (YTO) to Buenos Aires (EZE)
9.2/10 Wonderful! (1,001 reviews)
Hotel correcto. Habitación súper espaciosa y muy cómoda. Perfecta hora para salir. Y desayuno hasta tarde. 👌

Reviewed on Jun 14, 2026

Algodon Mansion

Algodon Mansion

5 out of 5
Buenos Aires Central Business District
Price was CA $3,175, price is now CA $2,026 per person
CA $2,026
per person
Aug 23 - Aug 27
found 23 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Buenos Aires (EZE)
9.6/10 Exceptional! (113 reviews)
Great location, remarkable staff.

Reviewed on Jun 2, 2026

Ready to book your vacation to Mesopotamia?

 

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Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
The price is CA $189 per night from Jul 3 to Jul 4
CA $189
CA $189 total
Jul 3 - Jul 4
9.8/10 Exceptional! (38 reviews)
"Me da mucho gusto que Corrientes tenga un hotel de esta categoría. El personal es excelente, desde el front desk hasta las personas de mantenimiento. Cuando supieron que íbamos a casarnos nos enviaron una bandeja de refreshments con una hermosa tarjeta de felicitación. La presión y temperatura de ..."

Reviewed on Jun 6, 2026

Marriott Corrientes Hotel
Turismo Hotel Casino

Turismo Hotel Casino

2.5 out of 5
650 Entre Ríos Corrientes Corrientes
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from Jun 21 to Jun 22
CA $136
CA $136 total
Jun 21 - Jun 22
9/10 Wonderful! (7 reviews)
"The best place to stay in Corrientes! Amazing views"

Reviewed on Apr 7, 2026

Turismo Hotel Casino
Costarenas Hotel & Spa

Costarenas Hotel & Spa

3.5 out of 5
12 de Abril y Quiros Colon Entre Rios
Fully refundableReserve now, pay when you stay
The price is CA $171 per night from Jun 20 to Jun 21
CA $171
CA $171 total
Jun 20 - Jun 21
8.8/10 Excellent! (64 reviews)
"Estaba todo muy lindo"

Reviewed on Jun 8, 2026

Costarenas Hotel & Spa
See all 524 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Mesopotamia attractions

Parroquia Nuestra Señora de Itati

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
See properties

Frequently asked questions

Can I cancel my flight booking to Mesopotamia due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our Customer Service Portal. It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Mesopotamia that have flexible change policies?
Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia.
What are some of the general tips for travelers to Mesopotamia during the COVID-19 outbreak?
If it's your first time traveling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one:
  • Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening.
  • Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening.
  • Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Mesopotamia?
Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway.
How can I find cheap tickets to Mesopotamia?
One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal.
How much is a flight to Mesopotamia?
You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just .
What are the most popular airports to fly into in Mesopotamia?
Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month.
When is the cheapest time to fly to Mesopotamia?
Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Mesopotamia?
Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal.
Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples:
  • Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.
  • LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.