A river winding through a dense forest.

Mesopotamia Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Mesopotamia Vacation

When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.

The Latest Mesopotamia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 22 - Jan 27

    Krista Boutique Hotel + Flight

    Palermo
    4 nights
    4.0 star property
    9.2/10 - Wonderful (394 reviews)
    "Helpful staff, bright, modern clean rooms, great location. Would definitely recommend and stay here again."
    Reviewed October 28, 2026
    Roundtrip • Toronto (YYZ) - Buenos Aires (EZE)
    YYZ - EZE • 1 stop EZE - YYZ • 1 stop
    CA $2,065
    CA $1,509
    per traveller
    found 10 hours ago
    Krista Boutique Hotel
  • Dec 6 - Dec 13

    Palacio Duhau - Park Hyatt Buenos Aires + Flight

    Recoleta
    6 nights
    5.0 star property
    9.4/10 - Exceptional (531 reviews)
    "Las instalaciones son muy buenas sin embargo considero que deben de mejorar algunas cosas del cuarto. Cortinas y alfombras. Además el room services no tiene whisky después que cierra el bar del hotel, ilógico que un hotel con esa categoría tenga un problema tan sencillo de resolver."
    Reviewed November 5, 2026
    Roundtrip • Toronto (YYZ) - Buenos Aires (EZE)
    YYZ - EZE • 1 stop EZE - YYZ • 2 stops
    CA $8,123
    CA $5,516
    per traveller
    found 8 hours ago
    Palacio Duhau - Park Hyatt Buenos Aires
  • Jan 22 - Jan 27

    SLS Buenos Aires Puerto Madero + Flight

    Puerto Madero
    4 nights
    5.0 star property
    9.6/10 - Exceptional (405 reviews)
    Roundtrip • Toronto (YYZ) - Buenos Aires (EZE)
    YYZ - EZE • 1 stop EZE - YYZ • 1 stop
    CA $2,414
    CA $1,773
    per traveller
    found 10 hours ago
    SLS Buenos Aires Puerto Madero
  • Jan 12 - Jan 17

    Bulnes Eco Suites + Flight

    Palermo
    4 nights
    4.0 star property
    9.4/10 - Exceptional (1,319 reviews)
    "It is a good location with comfortable and large rooms. It is good value for a traveler who just wants accommodation. It has a front desk which is a plus."
    Reviewed October 29, 2026
    Roundtrip • Vancouver (YVR) - Buenos Aires (EZE)
    YVR - EZE • 2 stops EZE - YVR • 2 stops
    CA $2,180
    CA $1,626
    per traveller
    found 0 hours ago
    Bulnes Eco Suites
  • Jan 12 - Jan 17

    Faena Hotel Buenos Aires + Flight

    Puerto Madero
    4 nights
    5.0 star property
    9.0/10 - Wonderful (556 reviews)
    "Excelente todo"
    Reviewed October 4, 2026
    Roundtrip • Vancouver (YVR) - Buenos Aires (EZE)
    YVR - EZE • 2 stops EZE - YVR • 2 stops
    CA $2,680
    CA $2,010
    per traveller
    found 0 hours ago
    Faena Hotel Buenos Aires

Discover the most popular places to visit in Mesopotamia

Mesopotamia Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Mesopotamia vacation package cost?

Maybe less than you might think — from only CA $1,509, actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.

How do I get a cheap travel package to Mesopotamia?

Crafting your own Mesopotamia vacation package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.

What are the top hotels in Mesopotamia?

Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travelers.

How far in advance should I book my Mesopotamia vacation?

It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travelers occasionally nab a cheaper ticket just weeks before departure dates.

What does an Expedia Mesopotamia travel package include?

You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.

What should I know before booking a Mesopotamia travel package?

Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including vacation rentals such as mountain cabins and serviced residences. The list is almost endless!

Can I choose my airline with a Mesopotamia Expedia vacation package?

Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.

If I'm not able to travel, can I cancel my Mesopotamia vacation package?

Don't worry if you're rethinking your Mesopotamia vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realize life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.