Title: Mesopotamia Vacation Packages & Trips 2025/2026 from CA $1,942 | Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mesopotamia Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ### Your Mesopotamia Vacation When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with [Corrientes](https://www.expedia.ca/Corrientes.d6054203.Destination-Travel-Guides). Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. [Concordia](https://www.expedia.ca/Concordia.d892.Destination-Travel-Guides) is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation. ## Top Mesopotamia Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Pleno Palermo Soho](https://images.trvl-media.com/lodging/9000000/8420000/8412000/8411991/e2aacaa8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Pleno Palermo Soho Palermo CA $1,942 per person Jan 11 - Jan 17 found 1 day ago Roundtrip non-stop flight included Toronto (YYZ) to Buenos Aires (EZE) 18/10 Exceptional! (705 reviews) Room was fine. We got a deluxe with balcony-it faced the back of the hotel with a bunch small “ balconies “ with ac units and a large building/ construction. Too noisy to sit outside. The hotel welcomes pets- I think a cat must have recently stayed in the room ( I m allergic) so, difficult to manage. The location was great. Reviewed on Nov 10, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-01-11/2026-01-17/?FromAirport=YYZ&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=8411991&paandie=true&dealMarker=0lXGKnjKmfVqyQl-UWkZjOJizEX-769xniO-rHvbk9Qtb949d8bR3XBwhoYfyukw) ![Estancia Villa Maria](https://images.trvl-media.com/lodging/28000000/27600000/27598400/27598318/5a0df79c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Estancia Villa Maria CA $2,155 per person Feb 4 - Feb 9 found 1 day ago Roundtrip flight included Montreal (YUL) to Buenos Aires (EZE) 18.8/10 Exceptional! (97 reviews) We had an incredible stay. It was very relaxing. The staff is exceptional. The villa itself is very charming. It’s about 45 minutes from the city we had a car and would spend the day in the city and come back in the afternoon for a peaceful break. Reviewed on Aug 6, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-02-04/2026-02-09/?FromAirport=YUL&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=27598318&paandie=true&dealMarker=bO_UWYBN9M9-WjQSL9SG1eRoQDp5AQO7EcYt2hxpCxsaRwilWu_hWnFCHGXl7ZVN) ![Faena Hotel Buenos Aires](https://images.trvl-media.com/lodging/2000000/1060000/1052300/1052252/e6484222_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Faena Hotel Buenos Aires Puerto Madero CA $2,721 per person Jan 11 - Jan 17 found 1 day ago Roundtrip non-stop flight included Toronto (YYZ) to Buenos Aires (EZE) 17.6/10 Exceptional! (461 reviews) Definitely the best hotel in Buenos Aires. Front desk was amazing! Thanks for the room upgrade for my birthday week. Breakfast was delicious and always enjoyable. Restaurant and pool service was slow but seemed like they improved during the 10 days at the hotel. The spa was very nice. The gym was good, but needs newer cardio. The pool is gorgeous and worth choosing Faena. Reviewed on Nov 9, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-01-11/2026-01-17/?FromAirport=YYZ&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1052252&paandie=true&dealMarker=0lXGKnjKmfVqyQl-UWkZjHdmXTwCScLWJyTw5jIHN0dotn5SldF-86uJicqiTzlK) ![Palladio Hotel Buenos Aires - MGallery Collection](https://images.trvl-media.com/lodging/31000000/30080000/30073400/30073367/7262952a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Palladio Hotel Buenos Aires - MGallery Collection Recoleta CA $2,633 per person Jan 11 - Jan 17 found 1 day ago Roundtrip non-stop flight included Toronto (YYZ) to Buenos Aires (EZE) 19.6/10 Exceptional! (620 reviews) The staff is very attentive. Philip was a big help, he helped us numerous times with directions. We will be back. Reviewed on Nov 15, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-01-11/2026-01-17/?FromAirport=YYZ&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=30073367&paandie=true&dealMarker=koEcQNa1DcJ_UZmfWSEJe56-MU4IRlTA9sjP10sWVcK5_pGXpQlQn-jnryCCAbNx) ![Hotel Club Frances](https://images.trvl-media.com/lodging/5000000/4920000/4914500/4914467/f4102dc9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Club Frances Recoleta CA $2,124 per person Jan 11 - Jan 17 found 1 day ago Roundtrip non-stop flight included Toronto (YYZ) to Buenos Aires (EZE) 18.8/10 Exceptional! (630 reviews) Lovely boutique hotel with standout service from Florencia and Natalia. Room was spacious with a gorgeous shower. Reviewed on Oct 16, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-01-11/2026-01-17/?FromAirport=YYZ&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=4914467&paandie=true&dealMarker=koEcQNa1DcJ_UZmfWSEJexq4CorPteAKM43RnUdx0BQK-cNlR_x5YiDF4XF3nRGM) ## Ready to book your vacation to Mesopotamia? Choose your dates ## Mesopotamia Hotel Deals ![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Corrientes Hotel Av Costanera Juan Pablo II y Lavalle, Corrientes Fully refundableReserve now, pay when you stay CA $175 CA $175 total Dec 5 - Dec 6 10/10 Exceptional! (3 reviews) Very nice hotel Reviewed on Nov 9, 2025 [](https://expedia.ca/Hotel-Search?startDate=05%2F12%2F2025&endDate=06%2F12%2F2025&selected=117154160&PinnedHotelID=117154160&HadPinnedHotel=true®ionId=6208836) ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### O2 Hotel Gualeguaychú 115 3 de Febrero, Gualeguaychú, Entre Ríos Fully refundableReserve now, pay when you stay CA $47 CA $47 total Nov 18 - Nov 19 7.6/10 Good! (63 reviews) Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. Reviewed on Jan 2, 2025 [](https://expedia.ca/Hotel-Search?startDate=18%2F11%2F2025&endDate=19%2F11%2F2025&selected=76459363&PinnedHotelID=76459363&HadPinnedHotel=true®ionId=6208836) ![La Casona de Susana](https://images.trvl-media.com/lodging/5000000/4420000/4411700/4411601/456e237c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Casona de Susana 3 de Febrero 448, Colon, Entre Rios CA $67 CA $67 total Dec 3 - Dec 4 La propietaria respeta el precio acordado. En verano si usás más de 8 horas por día el aire acondicionado te cobran un plus. Reviewed on Mar 13, 2023 [](https://expedia.ca/Hotel-Search?startDate=03%2F12%2F2025&endDate=04%2F12%2F2025&selected=4411601&PinnedHotelID=4411601&HadPinnedHotel=true®ionId=6208836) [See all 491 properties in Mesopotamia](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=18%2F11%2F2025&endDate=19%2F11%2F2025®ionId=6208836) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ### Discover the most popular places to visit in Mesopotamia ![El Palmar National Park](https://mediaim.expedia.com/destination/2/04a7d2876dc5e0ece83e6d60439d3e42.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### El Palmar National Park Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay. [](https://expedia.ca/El-Palmar-National-Park-Ubajay.d6096826.Vacation-Attraction) ## Frequently asked questions ### Can I cancel my flight booking to Mesopotamia due to COVID-19? > If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our [Customer Service Portal](https://www.expedia.ca/service/?langId=1033). It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps. ### What's the best way to find cheap flights to Mesopotamia that have flexible change policies? > Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia. ### What are some of the general tips for travelers to Mesopotamia during the COVID-19 outbreak? > If it's your first time traveling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one: > > - Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing. > - Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity. > - Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection. > - You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening. > - Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening. > - Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings. ### Which airlines fly to Mesopotamia? > Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway. ### How can I find cheap tickets to Mesopotamia? > One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal. ### How much is a flight to Mesopotamia? > You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just . ### What are the most popular airports to fly into in Mesopotamia? > Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month. ### When is the cheapest time to fly to Mesopotamia? > Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays. ### How much is a plane ticket to Mesopotamia? > Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal. ### Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies? > In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples: > > - Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant. > - LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights. > - American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant. ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)