Mesopotamia Vacation Packages
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Your Mesopotamia Vacation
When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.
Top Mesopotamia Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Mio Buenos Aires
Recoleta
CA $2,186
per person
Oct 22 - Oct 28
found 10 hours ago
Roundtrip flight included
Vancouver (YVR) to Buenos Aires (EZE)
9.4/10 Exceptional! (660 reviews)
Thank you for a wonderful stay! Beautiful and comfortable room, excellent breakfast and attentive staff.
Reviewed on Aug 23, 2026
Krista Boutique Hotel
Palermo
CA $2,316
per person
Oct 2 - Oct 8
found 1 day ago
Roundtrip flight included
Vancouver (YVR) to Buenos Aires (EZE)
9.2/10 Wonderful! (372 reviews)
La atención fue de lo mejor y la ubicación es privilegiada. Habitacion excepcional, con el
único detalle es que las housekeepers deben de cambiar o bien doblar las toallas cuando esto lo amerita, por lo demás espectacular 💯✅
Reviewed on Aug 22, 2026
Ready to book your vacation to Mesopotamia?
Mesopotamia Hotel Deals
Marriott Corrientes Hotel
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
CA $221
CA $221 total
Aug 29 - Aug 30
9.8/10 Exceptional! (43 reviews)
"Impecable, 10/10"
Reviewed on Aug 16, 2026
O2 Hotel Gualeguaychú
115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
CA $51
CA $51 total
Sep 15 - Sep 16
Hathor Concordia
Ruta Nacional 14-km 264.5 Concordia Entre Rios
Fully refundableReserve now, pay when you stay
CA $67
CA $82 total
Aug 31 - Sep 1
8.8/10 Excellent! (389 reviews)
"AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road."
Reviewed on Dec 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Mesopotamia attractions
Basilica Nuestra Senora De Itati
Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
El Palmar National Park
8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
Costanera de Corrientes
9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
Termas de Federacion
10.0/10 (2 reviews)
Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.
Victoria Beach
If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area.
Concepción del Uruguay City Racetrack
You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
Termas Concepcion Entrerios
Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this amusement park in Concepción del Uruguay. Experience the area's art scene and museums.
Portal Carambola
You can take time to visit Portal Carambola during your travels to Concepción. While you're in the area, wander around the parks.
Frequently asked questions
How much does a Mesopotamia vacation package cost?
Maybe less than you might think — from only CA $1,606, actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia vacation package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travelers.
How far in advance should I book my Mesopotamia vacation?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travelers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including vacation rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia vacation package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia vacation package?
Don't worry if you're rethinking your Mesopotamia vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realize life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
