Mesopotamia Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Mesopotamia Vacation

When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.

Top Mesopotamia Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Bulnes Eco Suites

Bulnes Eco Suites

4 out of 5
Palermo
Price was CA $1,882, price is now CA $1,331 per person
CA $1,331
per person
Jun 17 - Jun 23
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Buenos Aires (EZE)
9.4/10 Exceptional! (1,235 reviews)
Fantastic stay in a convenient location. Friendly staff, reception 24/7, spacious and clean room, comfy beds. Walking distance to Alto Palermo, lots of shops and restaurants/coffee shops and public transport. I would totally recommend and we will come back on ourcnext trip to gorgeous Buenos Aires.

Reviewed on May 3, 2026

Mio Buenos Aires

Mio Buenos Aires

4.5 out of 5
Recoleta
Price was CA $3,708, price is now CA $2,580 per person
CA $2,580
per person
Jul 14 - Jul 20
found 10 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Buenos Aires (EZE)
9.4/10 Exceptional! (624 reviews)
The rooms were clean and the staff was very friendly and helpful. I spent time in two rooms but in one of the rooms (on the 7th floor) there were lots of noises like the walls were thin and I could hear the plumbing or something (I didn’t experience that on the 3rd floor).

Reviewed on Apr 30, 2026

Casa Lucia Member of Melia Collection

Casa Lucia Member of Melia Collection

5 out of 5
El Centro
Price was CA $2,811, price is now CA $1,957 per person
CA $1,957
per person
Jun 17 - Jun 23
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Buenos Aires (EZE)
9.6/10 Exceptional! (143 reviews)
Loved this hotel. Great location, staff was awesome and so attentive and helpful. Definitely I will be staying there next time I go to BA

Reviewed on May 4, 2026

Algodon Mansion

Algodon Mansion

5 out of 5
Buenos Aires Central Business District
Price was CA $3,849, price is now CA $2,728 per person
CA $2,728
per person
Jul 14 - Jul 20
found 10 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Buenos Aires (EZE)
9.6/10 Exceptional! (112 reviews)
What a fabulous hotel to stay in. We had a wonderful vacation. Our suite was very quiet, spacious and well appointed. The concierge team stood out and coordinated day trips and dinners. These experiences made our trip to Buenos Aires extra special. Highly recommend staying at the Algodon Mansion.

Reviewed on Feb 15, 2026

Krista Boutique Hotel

Krista Boutique Hotel

4 out of 5
Palermo
Price was CA $2,216, price is now CA $1,658 per person
CA $1,658
per person
Jun 17 - Jun 23
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Buenos Aires (EZE)
9.2/10 Wonderful! (346 reviews)
Great property and location. Rooms spacious and well appointed. Staff is superb

Reviewed on May 6, 2026

Ready to book your vacation to Mesopotamia?

 

Choose your dates

Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
The price is CA $170 per night from May 13 to May 14
CA $170
CA $170 total
May 13 - May 14
10/10 Exceptional! (27 reviews)
Great

Reviewed on Apr 22, 2026

Marriott Corrientes Hotel
Hathor Concordia

Hathor Concordia

3 out of 5
Ruta Nacional 14-km 264.5 Concordia Entre Rios
Fully refundableReserve now, pay when you stay
The price is CA $76 per night from May 7 to May 8
CA $76
CA $91 total
May 7 - May 8
8.6/10 Excellent! (379 reviews)
AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road.

Reviewed on Dec 22, 2025

Hathor Concordia
Turismo Hotel Casino

Turismo Hotel Casino

2.5 out of 5
650 Entre Ríos Corrientes Corrientes
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from May 10 to May 11
CA $136
CA $136 total
May 10 - May 11
9/10 Wonderful! (7 reviews)
The best place to stay in Corrientes! Amazing views

Reviewed on Apr 7, 2026

Turismo Hotel Casino
See all 521 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Mesopotamia

Parque Nacional El Palmar, Entre Rios, Argentina.

El Palmar National Park

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

El Palmar National Park

Frequently asked questions

Can I cancel my flight booking to Mesopotamia due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our Customer Service Portal. It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Mesopotamia that have flexible change policies?
Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia.
What are some of the general tips for travelers to Mesopotamia during the COVID-19 outbreak?
If it's your first time traveling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one:
  • Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening.
  • Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening.
  • Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Mesopotamia?
Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway.
How can I find cheap tickets to Mesopotamia?
One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal.
How much is a flight to Mesopotamia?
You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just .
What are the most popular airports to fly into in Mesopotamia?
Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month.
When is the cheapest time to fly to Mesopotamia?
Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Mesopotamia?
Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal.
Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples:
  • Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.
  • LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.