Mesopotamia Vacation Packages
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Your Mesopotamia Vacation
When you long for adventure, book a Mesopotamia vacation package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customize your next Mesopotamia vacation.
Top Mesopotamia Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Live Devoto Boutique Apartments
Villa Devoto
CA $2,166
per person
Oct 24 - Oct 31
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Buenos Aires (EZE)
10/10 Exceptional! (2 reviews)
The apartment was more than I was expecting. They have a roof that is a plus. Modern, clean and super confortable place.
Reviewed on Jun 8, 2026
Palacio Duhau - Park Hyatt Buenos Aires
Recoleta
CA $3,239
per person
Oct 27 - Nov 2
found 12 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Buenos Aires (EZE)
9.4/10 Exceptional! (518 reviews)
Excelente hotel. Suite Park vale a estadia
Café da manhã muito bom. Localização perfeita.
Lindo jardim.
Reviewed on Jul 4, 2026
Ready to book your vacation to Mesopotamia?
Mesopotamia Hotel Deals
Marriott Corrientes Hotel
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
CA $197
CA $197 total
Sep 20 - Sep 21
9.8/10 Exceptional! (46 reviews)
"Impecable"
Reviewed on Sep 2, 2026
Costarenas Hotel & Spa
12 de Abril y Quiros Colon Entre Rios
Fully refundableReserve now, pay when you stay
CA $168
CA $168 total
Sep 12 - Sep 13
8.8/10 Excellent! (64 reviews)
"Estaba todo muy lindo"
Reviewed on Jun 8, 2026
O2 Hotel Gualeguaychú
115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
CA $48
CA $48 total
Sep 17 - Sep 18
7.8/10 Good! (93 reviews)
"Hola,todos los chicos con excelente atencion,muy dispuestos y nos hicieron muy buenas recomendaciones,si tuviera que opinar al fuera de lo expresado,es el servicio de desayuno,muy muy muy básico,2 medialunas chicas " peladas " y 3 tostadas y bien tostadas,sería agradable pongan alguna otra cosita ..."
Reviewed on Aug 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Mesopotamia attractions
El Palmar National Park
8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
Basilica Nuestra Senora De Itati
Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
Costanera de Corrientes
9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
Termas de Federacion
10.0/10 (2 reviews)
Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.
Concepción del Uruguay City Racetrack
You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
Victoria Beach
If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area.
Portal Carambola
You can take time to visit Portal Carambola during your travels to Concepción. While you're in the area, wander around the parks.
Termas Concepcion Entrerios
Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this amusement park in Concepción del Uruguay. Experience the area's art scene and museums.
Frequently asked questions
How much does a Mesopotamia vacation package cost?
Maybe less than you might think — from only CA $1,832, actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia vacation package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travelers.
How far in advance should I book my Mesopotamia vacation?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travelers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including vacation rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia vacation package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia vacation package?
Don't worry if you're rethinking your Mesopotamia vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realize life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
