Title: Adults Only Vacations in Southeastern United States 2025/2026 | Expedia.ca ![](https://images.trvl-media.com/place/6300606/fe45af26-0a11-4b82-a114-0684835f5ed5.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Southeastern United States Adults Only Vacations ## Book a Hotel + Flight or Car together to unlock savings Stay added Flight added Car - Economy - Premium economy - Business class - First class Leaving from Going to Dates Travellers ## Room 1 Adults ChildrenAges 2 to 17 InfantsYounger than 2 I only need accommodation for part of my trip - ## Plan, book, travel with confidence ### Better together Save up to CA $1,096 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Plan, book, and manage your trip all in one place ## Flight and Adults Only hotel deals in Southeastern United States Price found within the past 48 hours. Click for updated prices. ![The Standard Spa Miami Beach](https://images.trvl-media.com/lodging/1000000/130000/126700/126664/051f7ed8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Standard Spa Miami Beach CA $1,639 per person Dec 24 - Dec 27 found 16 hours ago Roundtrip flight included Toronto (YYZ) to Miami (MIA) 8.8/10 Excellent! (1,005 reviews) Clean room, great pool staff. Reviewed on Sep 30, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-24/2025-12-27/?FromAirport=YYZ&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&hotelId=126664&paandie=true&HotelClass=40&dealMarker=hEcxEAl0cQr8TKY7Kq7rzqWiRvOxmSlvVHKhVWyPFW9cXaprunzBavtgKVmWIERl) ![Southernmost House](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/9dea706f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Southernmost House Old Town Key West CA $1,646 per person Nov 21 - Nov 24 found 21 hours ago Roundtrip non-stop flight included Buffalo (BUF) to Key West (EYW) 9.4/10 Exceptional! (1,008 reviews) The pool /ocean view was beautiful- clean - and so private!! Pool was open for night swimming until 10pm -which was so relaxing!! Bar/restaurant on the premises - comp to your room! Get the Lobster pizza!! Beautiful sunrise viewing! Rooms are clean and cozy! Nice towels and crisp clean bedding. European style breakfast served daily and was very good! Yummy pastries! Staff is very friendly and accommodating! Would definitely stay here again! Reviewed on Oct 14, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-11-21/2025-11-24/?FromAirport=BUF&Destination=EYW&NumRoom=1&NumAdult=2&NumChild=0&hotelId=3830519&paandie=true&HotelClass=40&dealMarker=MkQLtkNAfofyS6wruIyPfCLQd_OsXiQFEhjWpXXwhH1_VGWEWk3Y4QcdvDLwhSir) Don't see what you're looking for? See all available trips from Columbus to Southeastern United States [View all trips](https://expedia.ca/go/package/search/FlightHotel/2025-11-22/2025-11-29/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=ORL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Adults Only holidays in Southeastern United States Price found within the past 48 hours. Click for updated prices. ![The Standard Spa Miami Beach](https://images.trvl-media.com/lodging/1000000/130000/126700/126664/051f7ed8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Standard Spa Miami Beach CA $1,639 per person Dec 24 - Dec 27 found 16 hours ago Roundtrip flight included Toronto (YYZ) to Miami (MIA) 8.8/10 Excellent! (1,005 reviews) Clean room, great pool staff. Reviewed on Sep 30, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-24/2025-12-27/?FromAirport=YYZ&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&hotelId=126664&paandie=true&HotelClass=40&dealMarker=hEcxEAl0cQr8TKY7Kq7rzqWiRvOxmSlvVHKhVWyPFW9cXaprunzBavtgKVmWIERl) ![Southernmost House](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/9dea706f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Southernmost House Old Town Key West CA $1,646 per person Nov 21 - Nov 24 found 21 hours ago Roundtrip non-stop flight included Buffalo (BUF) to Key West (EYW) 9.4/10 Exceptional! (1,008 reviews) The pool /ocean view was beautiful- clean - and so private!! Pool was open for night swimming until 10pm -which was so relaxing!! Bar/restaurant on the premises - comp to your room! Get the Lobster pizza!! Beautiful sunrise viewing! Rooms are clean and cozy! Nice towels and crisp clean bedding. European style breakfast served daily and was very good! Yummy pastries! Staff is very friendly and accommodating! Would definitely stay here again! Reviewed on Oct 14, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-11-21/2025-11-24/?FromAirport=BUF&Destination=EYW&NumRoom=1&NumAdult=2&NumChild=0&hotelId=3830519&paandie=true&HotelClass=40&dealMarker=MkQLtkNAfofyS6wruIyPfCLQd_OsXiQFEhjWpXXwhH1_VGWEWk3Y4QcdvDLwhSir) Don't see what you're looking for? See all available trips from Columbus to Southeastern United States [View all trips](https://expedia.ca/go/package/search/FlightHotel/2025-11-22/2025-11-29/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=ORL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Adults Only holidays in Southeastern United States Price found within the past 48 hours. Click for updated prices. ![Shoreline Island Resort - Exclusively Adult](https://images.trvl-media.com/lodging/3000000/2630000/2626200/2626102/382198c3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Shoreline Island Resort - Exclusively Adult CA $1,022 per person Dec 18 - Dec 22 found 1 hour ago Roundtrip non-stop flight included Montreal (YUL) to Tampa (TPA) 9.2/10 Wonderful! (1,399 reviews) We had a great time. The people are really helpful. Will definitely be back Reviewed on Oct 22, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-18/2025-12-22/?FromAirport=YUL&Destination=TPA&NumRoom=1&NumAdult=2&NumChild=0&hotelId=2626102&paandie=true&dealMarker=hEcxEAl0cQr8TKY7Kq7rzgnfVdlkRY5NhBRuztxkMqAdwZ3lMy0toRGMPPo6CP5R) ![The Standard Spa Miami Beach](https://images.trvl-media.com/lodging/1000000/130000/126700/126664/051f7ed8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Standard Spa Miami Beach CA $2,095 per person Jan 1 - Jan 5 found 19 hours ago Roundtrip non-stop flight included Toronto (YYZ) to Miami (MIA) 8.8/10 Excellent! (1,005 reviews) Clean room, great pool staff. Reviewed on Sep 30, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2026-01-01/2026-01-05/?FromAirport=YYZ&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&hotelId=126664&paandie=true&dealMarker=zsdb7AqbqTyQd7e-XzjFS1I4Li5GiZTn0zD9xUo6CFcMXUnYG5nmdbtINxQJ6sEf) ![The Southernmost Inn - Adults Only](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/2b7e8bad_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Southernmost Inn - Adults Only Old Town Key West CA $1,421 per person Nov 22 - Nov 26 found 3 hours ago Roundtrip non-stop flight included Toronto (YYZ) to Key West (EYW) 8.2/10 Very Good! (1,171 reviews) everyone was helpful Reviewed on Oct 20, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-11-22/2025-11-26/?FromAirport=YYZ&Destination=EYW&NumRoom=1&NumAdult=2&NumChild=0&hotelId=4280752&paandie=true&dealMarker=hEcxEAl0cQr8TKY7Kq7rzgq_TRs5m4RyEYZOHta4MYbNSbboYH6_asP4DtPMqeQB) Don't see what you're looking for? See all available trips from Columbus to Southeastern United States [View all trips](https://expedia.ca/go/package/search/FlightHotel/2025-11-22/2025-11-29/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=ORL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Adults Only Hotels in Southeastern United States ![Shoreline Island Resort - Exclusively Adult](https://images.trvl-media.com/lodging/3000000/2630000/2626200/2626102/382198c3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Shoreline Island Resort - Exclusively Adult 14200 Gulf Boulevard, Madeira Beach, FL - 4 hours drive from Walt Disney World® Resort Stay at this 3-star beach aparthotel in Madeira Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ... 9/10 Wonderful! (1,399 reviews) "Our gulf view room had a full unobstructed view of the ocean and pool. The staff was great at communicating some issues with the non functioning elevators. The staff were all very friendly. awe The area in general was significantly damaged in 2024 by Helene & Milton. Although there were still some ..." Reviewed on Oct 15, 2025 [](https://expedia.ca/St-Petersburg-Clearwater-Hotels-Shoreline-Island-Resort-Exclusively-Adult.h2626102.Hotel-Information) ![The Southernmost Inn - Adults Only](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/2b7e8bad_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Southernmost Inn - Adults Only 525 United Street, Key West, FL - 11 hours drive from Walt Disney World® Resort Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ... 8.2/10 Very Good! (1,177 reviews) "everyone was helpful" Reviewed on Oct 20, 2025 [](https://expedia.ca/Key-West-Hotels-The-Southernmost-Inn-Adults-Only.h4280752.Hotel-Information) ![Paradise Inn Key West - Adults Only](https://images.trvl-media.com/lodging/4000000/3930000/3924900/3924835/069168f1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Paradise Inn Key West - Adults Only 819 Simonton Street, Key West, FL - 11 hours drive from Walt Disney World® Resort Stay at this 3.5-star business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and daily housekeeping. Our guests praise the breakfast ... 9/10 Wonderful! (1,011 reviews) "Handy location, quiet, well kept, helpful staff." Reviewed on Oct 17, 2025 [](https://expedia.ca/Key-West-Hotels-Paradise-Inn-Key-West-Adults-Only.h3924835.Hotel-Information) [See all 458,910 properties in Southeastern United States](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6209937) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Southeastern United States](https://expedia.ca/Cheap-Flights-To-Southeastern-United-States.d6209937.Travel-Guide-Flights)[Southeastern United States Hotels](https://expedia.ca/Southeastern-United-States-Hotels.d6209937.Travel-Guide-Hotels)[Southeastern United States Vacation Rentals](https://expedia.ca/Southeastern-United-States-Vacation-Rentals.d6209937.Travel-Guide-VacationRentals)[Southeastern United States Car Rentals](https://expedia.ca/Car-Rentals-In-Southeastern-United-States.d6209937.Car-Rental-Guide)[Southeastern United States Vacations](https://expedia.ca/Southeastern-United-States.d6209937.Destination-Travel-Guides)[Things to do in Southeastern United States](https://expedia.ca/Things-To-Do-In-Southeastern-United-States.d6209937.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)