Cheap flights from Rionegro to Panama City from CA $257

    Plan, book, fly with confidence
  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • payments icon
    Earn twice
    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Rionegro (MDE) to Panama City (PTY)

Prices were available within the past 7 days and start at CA $257 for one-way flights and CA $421 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu., May 30 - Sun., Jun. 2
MDE
Medellín
PTY
Panama City
CA $421 Roundtrip, found 8 hours ago
CA $421
Roundtrip
found 8 hours ago
Select Copa flight, departing Thu., May 30 from Medellín to Panama City, returning Sun., Jun. 2, priced at CA $421 found 8 hours ago
Copa
Sat., Jun. 1 - Tue., Jun. 11
MDE
Medellín
PTY
Panama City
CA $423 Roundtrip, found 6 days ago
CA $423
Roundtrip
found 6 days ago
Select Copa flight, departing Sat., Jun. 1 from Medellín to Panama City, returning Tue., Jun. 11, priced at CA $423 found 6 days ago
Copa
Thu., May 30 - Sun., Jun. 2
MDE
Medellín
PTY
Panama City
CA $455 Roundtrip, found 8 hours ago
CA $455
Roundtrip
found 8 hours ago
Select Copa flight, departing Thu., May 30 from Medellín to Panama City, returning Sun., Jun. 2, priced at CA $455 found 8 hours ago
Copa
Sat., Jun. 1 - Tue., Jun. 11
MDE
Medellín
PTY
Panama City
CA $455 Roundtrip, found 6 days ago
CA $455
Roundtrip
found 6 days ago
Select Copa flight, departing Sat., Jun. 1 from Medellín to Panama City, returning Tue., Jun. 11, priced at CA $455 found 6 days ago
Copa
Thu., May 30 - Sun., Jun. 2
MDE
Medellín
PTY
Panama City
CA $488 Roundtrip, found 8 hours ago
CA $488
Roundtrip
found 8 hours ago
Select Copa flight, departing Thu., May 30 from Medellín to Panama City, returning Sun., Jun. 2, priced at CA $488 found 8 hours ago
Copa
Fri., May 31 - Tue., Jun. 4
MDE
Medellín
PTY
Panama City
CA $518 Roundtrip, found 10 hours ago
CA $518
Roundtrip
found 10 hours ago
Select Copa flight, departing Fri., May 31 from Medellín to Panama City, returning Tue., Jun. 4, priced at CA $518 found 10 hours ago
*Available to Expedia members.