Find Spa Hotels in Santee, SC from CA $76

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Check prices for these dates

Tonight
Nov 10 - Nov 11
Tomorrow
Nov 11 - Nov 12
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22
No exact matches found, but these alternatives could be just right

Recommended hotels in Santee

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

1. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,002 reviews)
The price is CA $174
CA $193 total
includes taxes & fees
Nov 25 - Nov 26
Hampton Inn Santee-I-95
A patio area with wicker furniture, a stone fire pit, and outdoor seating.

2. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,004 reviews)
The price is CA $177
CA $196 total
includes taxes & fees
Nov 16 - Nov 17
Fairfield Inn & Suites by Marriott Santee
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

3. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (1,016 reviews)
The price is CA $149
CA $165 total
includes taxes & fees
Nov 29 - Nov 30
Tru By Hilton Santee
A hotel room with a bed, bedside table, lamp, and a mirror.

4. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,516 reviews)
The price is CA $113
CA $125 total
includes taxes & fees
Nov 11 - Nov 12
Baymont by Wyndham Santee
A hotel entrance with a sign reading "Best Western PLISS."

5. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
The price is CA $167
CA $185 total
includes taxes & fees
Nov 16 - Nov 17
Best Western Plus Santee Inn
A water park with a pool, slides, and umbrellas.

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
The price is CA $176
CA $196 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Santee by IHG
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,001 reviews)
The price is CA $152
CA $169 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Inn & Suites Santee
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (788 reviews)
The price is CA $90
CA $100 total
includes taxes & fees
Nov 11 - Nov 12
Travelodge by Wyndham Santee
A modern bathroom with a sink, toilet, and shower area.

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (477 reviews)
The price is CA $90
CA $100 total
includes taxes & fees
Nov 18 - Nov 19
Super 8 by Wyndham Santee/I-95
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
5.8 out of 10, (616 reviews)
The price is CA $77
CA $92 total
includes taxes & fees
Dec 1 - Dec 2
Quality Inn & Suites Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Santee

Pool
Breakfast included

Top Santee Hotel Reviews

A modern dining area with tables and chairs, large windows with sheer curtains, and pendant lighting.
Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
Orangeburg

10/10 Excellent

Our check in with Tanya was great! She was sooo friendly and efficient. And gave us great advice about getting dinner as we were late :-)
Canada
Monique
Reviewed October 1, 2023
Hampton Inn & Suites Orangeburg

Find out more about Santee

Top Santee attractions for a relaxing vacation

Santee, South Carolina, is a hidden gem for travellers seeking a rejuvenating escape with spa hotels to enhance their stay. Begin your journey at Santee State Park, where you can enjoy stunning views of Lake Marion and explore over 2,500 acres of lush woodlands, perfect for a serene hike or a family picnic. For those who enjoy fishing or boating, the lake is a prime spot to cast a line or take a leisurely cruise. After a day outdoors, indulge in some retail therapy at local shops, where you can find unique gifts and souvenirs. Don’t miss the nearby Santee Cooper Country Club, which offers a picturesque golf course that is both challenging and enjoyable for all skill levels. Finally, unwind with a spa treatment at one of Santee's premier hotels, where attentive service and luxurious amenities await. Staying in this area not only provides easy access to these activities but also ensures you can retreat to a tranquil environment, making your family holiday both exciting and relaxing.

Frequently Asked Questions

Looking for a spa hotel in Santee?

Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.

What's there to see and do in Santee?

Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee State Park, and Lake Marion. If you have a bit of extra time while you’re in the area, you might want to check out Santee National Golf Club and Santee Town Hall.

What is a Santee spa hotel?

Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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