Santa Cruz Vacation Packages

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Your Santa Cruz Vacation

With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.

Top Santa Cruz Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

Equipetrol
CA $1,088
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Santa Cruz (VVI)
9.4/10 Exceptional! (134 reviews)
Camino Real Hotel

Camino Real Hotel

CA $1,330
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Santa Cruz (VVI)
9/10 Wonderful! (439 reviews)
The hotel is always as expected. Very clean rooms. Staff is great. Close to shopping. Delicious breakfast menu

Reviewed on Sep 15, 2026

Hotel Cortez

Hotel Cortez

Equipetrol
CA $1,217
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Santa Cruz (VVI)
9.4/10 Exceptional! (150 reviews)
Awesome Hotel

Reviewed on Sep 11, 2026

HOTEL OSHO

HOTEL OSHO

CA $1,099
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Santa Cruz (VVI)
9.2/10 Wonderful! (54 reviews)
Good

Reviewed on Aug 22, 2026

Sun Hotel

Sun Hotel

CA $1,206
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Santa Cruz (VVI)
8.2/10 Very good! (400 reviews)
Very nice place to stay. Close to the airport with shuttle to the hotel.

Reviewed on Sep 10, 2026

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
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Equipetrol

Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Ventura Mall.

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Centro Histórico

4 out of top 10 points of interest in this area

If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.

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Hamacas

While Hamacas isn't home to many top sights, Las Brisas Shopping Center and Santa Cruz Zoo are some notable places to visit nearby.

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Urubó

While Urubó might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Guembe Biocenter and Ventura Mall.

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Zona Sur (South Zone)

Zona Sur (South Zone) might not have many top sights, but Cine Center and Blacutt Square are two attractions nearby that you can check out.

Ready to book your vacation to Santa Cruz?

Choose your dates

Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
CA $68
CA $68 total
Oct 16 - Oct 17
Ibis Santa Cruz DE LA Sierra
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ave. San Martin, #455 Santa Cruz
CA $201
CA $201 total
Oct 2 - Oct 3
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
CA $148
CA $148 total
Oct 2 - Oct 3
Marriott Santa Cruz de la Sierra Hotel
See all 317 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
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An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)
One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.
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Ventura Mall

9.0/10 (183 reviews)
During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.
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Guembe Biocenter

8.8/10 (60 reviews)
Explore the great outdoors at Guembe Biocenter, a lovely green space in Colinas del Urubo. While in the area, you can find time to visit its shops.
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Santa Cruz Zoo

8.4/10 (53 reviews)
Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.
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Las Brisas Shopping Center

8.4/10 (40 reviews)
You can find the perfect gifts to bring home at Las Brisas Shopping Center during your visit to Santa Cruz. While in the area, you can find time to visit its shops.
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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)
Catch an event at Ramon Tahuichi Aguilera Stadium during your trip to Santa Cruz. While in the area, you can find time to visit its shops.
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Cine Center

8.0/10 (53 reviews)
You can get tickets for a performance at Cine Center during your trip to Santa Cruz. While in the area, you can find time to visit its shops.
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What to do in Santa Cruz

Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and the river

Santa Cruz and Porongo: History, Markets, River, and Culture

CA $138
per adult
Santa Cruz and Porongo: History, Markets, River, and Culture
Fuerte de Samaipata, Bolivia

Samaipata Fort Tour: Ancient Ruins in 1 Full Day

CA $436
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
The Che Guevara route is the most peculiar tourist destination in Bolivia.

4D/3N Expedition: Che Guevara Route - Disconnect from the World

CA $1,106
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Offering excellent value package deals from CA $1,088 on Expedia, you'll be surprised at how little a vacation to Santa Cruz costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Cruz?
If you're hoping to score a cheap Santa Cruz vacation package, consider planning a trip in February, April and May. You're likely to find lower prices on accommodations and flights during these months — ideal for travellers wishing to save money.
How many days is enough for Santa Cruz?
With a well-organized travel plan, you can easily tick off the most popular Santa Cruz attractions in a handful of days. But if you'd like to discover hidden spots or go on day trips, think about booking your Santa Cruz vacation for longer.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz is a good vacation destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're travelling with the family or planning a trip with friends, a Santa Cruz vacation promises fun for everyone.
How to find the best Santa Cruz package deals?
Begin your search for a Santa Cruz package deal by entering your destination and preferred travel dates under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Santa Cruz package deal right away, simply play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Cruz adventure off to a flying start.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customized Santa Cruz vacation by choosing your favourite type of stay, airline and car class.
When to book a vacation package to Santa Cruz?
If you're planning a spontaneous Santa Cruz getaway, browse our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can find terrific deals on your flights and hotels by booking ahead.
How to plan a trip to Santa Cruz?
  1. Choose your dates: What you'd like to do in Santa Cruz and your preferred season can help you decide when to travel.
  2. Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your hotel will likely be the largest expense during your trip to Santa Cruz.
  3. Decide your trip length: Think about how long you'd like to spend discovering Santa Cruz. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  4. Combine your accommodations and airfare: Once you've settled on your travel dates and duration, book the right Santa Cruz vacation package for you.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.