Santa Cruz Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*

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Your Santa Cruz Vacation

With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
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Equipetrol

Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Municipal Library.

Find hotels in Equipetrol

Ready to book your vacation to Santa Cruz?

 

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Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is CA $48 per night from Nov 20 to Nov 21
CA $48
CA $48 total
Nov 20 - Nov 21
Ibis Santa Cruz DE LA Sierra
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
The price is CA $213 per night from Nov 14 to Nov 15
CA $213
CA $213 total
Nov 14 - Nov 15
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
The price is CA $172 per night from Nov 14 to Nov 15
CA $172
CA $172 total
Nov 14 - Nov 15
9/10 Wonderful! (261 reviews)
"Beautiful views and clean property. The food there is great, and it’s well located. However, the cleaning staff stole a $100 bill from my backpack and replaced it with a fake one. I would rather they just took the money, but replacing it with a fake note could’ve gotten me in serious trouble, and ..."

Reviewed on Oct 30, 2026

Marriott Santa Cruz de la Sierra Hotel
See all 318 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
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What to do in Santa Cruz

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

CA $121
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
The Che Guevara route is the most peculiar tourist destination in Bolivia.

Private Expedition 4D/3N: Samaipata, Che Route and Nature

CA $2,050
per adult
Private Expedition 4D/3N: Samaipata, Che Route and Nature
Samaipata Fort, Bolivia

Samaipata Fort Tour: Ancient Ruins in 1 Full Day

CA $587
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Offering excellent value package deals on Expedia, you'll be surprised at how little a vacation to Santa Cruz costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Cruz?
If you're hoping to score a cheap Santa Cruz vacation package, consider planning a trip in February, April and May. You're likely to find lower prices on accommodations and flights during these months — ideal for travellers wishing to save money.
How many days is enough for Santa Cruz?
With a well-organized travel plan, you can easily tick off the most popular Santa Cruz attractions in a handful of days. But if you'd like to discover hidden spots or go on day trips, think about booking your Santa Cruz vacation for longer.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz is a good vacation destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're travelling with the family or planning a trip with friends, a Santa Cruz vacation promises fun for everyone.
How to find the best Santa Cruz package deals?
Begin your search for a Santa Cruz package deal by entering your destination and preferred travel dates under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Santa Cruz package deal right away, simply play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Cruz adventure off to a flying start.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customized Santa Cruz vacation by choosing your favourite type of stay, airline and car class.
When to book a vacation package to Santa Cruz?
If you're planning a spontaneous Santa Cruz getaway, browse our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can find terrific deals on your flights and hotels by booking ahead.
How to plan a trip to Santa Cruz?

  1. Choose your dates: What you'd like to do in Santa Cruz and your preferred season can help you decide when to travel.
  2. Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your hotel will likely be the largest expense during your trip to Santa Cruz.
  3. Decide your trip length: Think about how long you'd like to spend discovering Santa Cruz. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  4. Combine your accommodations and airfare: Once you've settled on your travel dates and duration, book the right Santa Cruz vacation package for you.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.