Title: Santa Cruz Vacation Rentals from CA $37: Short-Term Rentals for 2026 | Expedia.ca

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![Santa Cruz](https://images.trvl-media.com/place/6053940/e11e6ae8-6b64-413c-ab96-4d4a810c4d57.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Santa Cruz Vacation Rentals

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## Check prices for these dates

Tonight

[Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2025-12-24&endDate=2025-12-25&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 25 - Dec 26](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2025-12-25&endDate=2025-12-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2025-12-26&endDate=2025-12-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6053940&startDate=2026-01-02&endDate=2026-01-04&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Cruz vacation rentals

![Standard Suite, 2 Single Beds](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/2b6207d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/3e13fa51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Suite | Private kitchen](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/c6295e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Suite | Living area](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/f61407b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Equipetrol Suites Apart Hotel

[](https://www.expedia.ca/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information)

Santa Cruz

8.4/10

Very good

(7)

"Perfect hotel"

![Turkey](https://a.travel-assets.com/egds/marks/flags/tr.svg)

Yener

CA $55

CA $55 total

Jan 22 - Jan 23, 2026

[](https://www.expedia.ca/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information)

![Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/12ef5e8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/9c72e6dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Apartment, 1 King Bed with Sofa bed, Terrace](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/72a81d70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/f316b83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Premium Suites Deluxe Aparthotel Equipetrol

[](https://www.expedia.ca/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information)

Santa Cruz

9.0/10

Wonderful

(81)

"Good price, great hotel!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James

CA $53

CA $53 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information)

![Children's area](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/81a819db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/494b7af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/6191ecc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/8ef87fa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chalet indept, amplio, acogedor, hermoso jardin Aire C wifi, espa.xcocinar.

[](https://www.expedia.ca/Santa-Cruz-Hotels-Chalet-Indept.h102550831.Hotel-Information)

Santa Cruz de la Sierra

CA $18

CA $48 total

Dec 26 - Dec 27

[](https://www.expedia.ca/Santa-Cruz-Hotels-Chalet-Indept.h102550831.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/47db859c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/3c35b4f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/71cea0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/7576825b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### A must-see studio apartment in Sirari-Equipetrol

[](https://www.expedia.ca/Santa-Cruz-Hotels-Vrbo-Property.h112789864.Hotel-Information)

Santa Cruz de la Sierra

CA $25

CA $73 total

Dec 27 - Dec 28

[](https://www.expedia.ca/Santa-Cruz-Hotels-Vrbo-Property.h112789864.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/99089910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/9c6cc778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/06f19d9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/ada57e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Traveler's Hideout

[](https://www.expedia.ca/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information)

Santa Cruz de la Sierra

10/10

Exceptional

(1)

"The place was cozy, neat, and th host was very attentive and supportive. I recomend this place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mauricio O.

CA $31

CA $67 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information)

![Business Apartment, Terrace (Plus) | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business Apartment, Terrace (Plus)](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/bb64c9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Apartment, Terrace | Private kitchen](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/cb07702a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Apartment, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/938b051b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apart Hotel Premium Suites Santa Cruz

[](https://www.expedia.ca/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information)

Santa Cruz

8.6/10

Excellent

(93)

"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

CA $37

CA $37 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/6663a26a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, stovetop](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/cd3d8ec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, stovetop](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/fa40047b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/20029dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

[](https://www.expedia.ca/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information)

Santa Cruz de la Sierra

CA $25

CA $59 total

Dec 29 - Dec 30

[](https://www.expedia.ca/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/e74af5c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/w1125h1500x0y7-eed47d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, City View](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/00e02072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, City View](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/c3714572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AMERICA APARTMENTS

[](https://www.expedia.ca/Santa-Cruz-Hotels-AMERICA-APARTMENTS.h120442096.Hotel-Information)

Santa Cruz

CA $75

CA $75 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-AMERICA-APARTMENTS.h120442096.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/1f2b7f07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Apartment, 1 Bedroom](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/4dc82f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/7e27a563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/2d503957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Terranova Suites

[](https://www.expedia.ca/Santa-Cruz-Hotels-Terranova-Suites.h10950250.Hotel-Information)

Santa Cruz

8.0/10

Very good

(90)

"Easy to access"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dorothy

CA $62

CA $62 total

Jan 24 - Jan 25, 2026

[](https://www.expedia.ca/Santa-Cruz-Hotels-Terranova-Suites.h10950250.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/edb1b53e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/753fda96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/f8f1dd6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/w1290h2293x0y251-5b08e5b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa de 2 Habitaciones en zona norte

[](https://www.expedia.ca/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information)

Santa Cruz de la Sierra

"Muy buen departamento, bien ubicado"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elva

CA $53

CA $81 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/4f23dcbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/2d334027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/c0d4ffcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/0a98f99b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apart Hotel Toborochi

[](https://www.expedia.ca/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information)

Santa Cruz

8.8/10

Excellent

(60)

"Property is close to nice dining options and entertainment places in Santa Cruz. The room is confortable and spacious "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stefany

[](https://www.expedia.ca/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/286c5800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/080d90c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/f2651883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/w1440h1927x0y24-b8c75958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dppto Luminoso y Lujoso en Equipe Zona Empresarial

[](https://www.expedia.ca/Santa-Cruz-Hotels-Dppto-Luminoso-Y-Lujoso-En-Equipe-Zona-Empresarial.h104261770.Hotel-Information)

Santa Cruz de la Sierra

CA $48

CA $89 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-Dppto-Luminoso-Y-Lujoso-En-Equipe-Zona-Empresarial.h104261770.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/5af8579d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/7409bf98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, toilet paper](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/09ebee18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/0f570e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartamento confortable para 2 personas

[](https://www.expedia.ca/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information)

Santa Cruz de la Sierra

CA $30

CA $57 total

Dec 29 - Dec 30

[](https://www.expedia.ca/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/643fec6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/bdb54fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/0ab047ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/6b46e3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury apartment

[](https://www.expedia.ca/Santa-Cruz-Hotels-Luxury-Apartment.h117687703.Hotel-Information)

Santa Cruz de la Sierra

CA $27

CA $62 total

Dec 26 - Dec 27

[](https://www.expedia.ca/Santa-Cruz-Hotels-Luxury-Apartment.h117687703.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/89a86d54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/08ad0327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/5c4a14d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, toilet paper](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/80f980e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy 2-bedroom apartment with AC, WiFi in enjoyable Santa Cruz

[](https://www.expedia.ca/Santa-Cruz-Hotels-Cozy-2-Bedroom-Apartment-With-AC.h112829576.Hotel-Information)

Santa Cruz de la Sierra

CA $41

CA $68 total

Dec 29 - Dec 30

[](https://www.expedia.ca/Santa-Cruz-Hotels-Cozy-2-Bedroom-Apartment-With-AC.h112829576.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/00581056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/c62e4215.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/d52d21aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/6a278a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment with balcony, swimming pool, gym, co-work at Equipe

[](https://www.expedia.ca/Santa-Cruz-Hotels-Modernity-And-Comfort-At-Equipe.h117789345.Hotel-Information)

Santa Cruz de la Sierra

CA $51

CA $86 total

Dec 31 - Jan 1, 2026

[](https://www.expedia.ca/Santa-Cruz-Hotels-Modernity-And-Comfort-At-Equipe.h117789345.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/1c0d3586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/9a14a6db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/d7013903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/6d55bdca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!

[](https://www.expedia.ca/Santa-Cruz-Hotels-COMODO-MONOAMBIENTE-EN-EQUIPETROL-CON-PISCINA-EN-CONDOMINIO.h100284354.Hotel-Information)

Santa Cruz de la Sierra

CA $55

CA $92 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-COMODO-MONOAMBIENTE-EN-EQUIPETROL-CON-PISCINA-EN-CONDOMINIO.h100284354.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/123000000/122870000/122866200/122866163/74e4542f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/123000000/122870000/122866200/122866163/c3389b13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122870000/122866200/122866163/2366c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/123000000/122870000/122866200/122866163/8edbbeb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### POX: Your favorite corner in the heart of Equipe!

[](https://www.expedia.ca/Santa-Cruz-Hotels-Vrbo-Property.h122866163.Hotel-Information)

Santa Cruz de la Sierra

CA $38

CA $66 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-Vrbo-Property.h122866163.Hotel-Information)

![House | Pool](https://images.trvl-media.com/lodging/16000000/15040000/15030900/15030862/cb1eeefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Vida

[](https://www.expedia.ca/Santa-Cruz-Hotels-Casa-Vida.h15030862.Hotel-Information)

Santa Cruz

9.0/10

Wonderful

(2)

"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg)

FERNANDO

[](https://www.expedia.ca/Santa-Cruz-Hotels-Casa-Vida.h15030862.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/121000000/120330000/120326900/120326835/e6f99b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120330000/120326900/120326835/0928750c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/121000000/120330000/120326900/120326835/a5f7d69c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120330000/120326900/120326835/e890d5a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 1-bedroom Modern Apartment in Sirari, Equipetrol

[](https://www.expedia.ca/Santa-Cruz-Hotels-1-Bedroom-Modern-Apartment-In-Sirari.h120326835.Hotel-Information)

Santa Cruz de la Sierra

CA $37

CA $68 total

Dec 25 - Dec 26

[](https://www.expedia.ca/Santa-Cruz-Hotels-1-Bedroom-Modern-Apartment-In-Sirari.h120326835.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08&regionId=6053940&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=APARTMENT)

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=APART_HOTEL)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=VACATION_HOME)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=CONDO)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=HOUSE_BOAT)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=COTTAGE)

Chalets

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=CHALET)

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia&regionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-24&d1=2026-03-24&endDate=2026-03-27&d2=2026-03-27&lodging=CABIN)

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## Top Santa Cruz Hotel Reviews

![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg)

### Ibis Santa Cruz DE LA Sierra

10/10 Excellent

"Good place in decent area and good price for the area"

[](https://expedia.ca/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information)

![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg)

### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent

"Great spacious property with nice pool!"

[](https://expedia.ca/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information)

![Chairú Eco Hotel](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg)

### Chairú Eco Hotel

10/10 Excellent

"Clean room and friendly staff "

[](https://expedia.ca/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information)

![Novotel Santa Cruz De La Sierra](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/864143db_y.jpg)

### Novotel Santa Cruz De La Sierra

10/10 Excellent

"Luxurious hotel,very chic and beautiful."

[](https://expedia.ca/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information)

![Hotel LP Santa Cruz Centro](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5_y.jpg)

### Hotel LP Santa Cruz Centro

10/10 Excellent

"Clean rooms, well kept facilities and nice staff"

[](https://expedia.ca/Santa-Cruz-Hotels-Hotel-LP-Santa-Cruz-Centro.h2761435.Hotel-Information)

![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg)

### Sun Hotel

10/10 Excellent

"spotless"

[](https://expedia.ca/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information)

![Marriott Santa Cruz de la Sierra Hotel](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf_y.jpg)

### Marriott Santa Cruz de la Sierra Hotel

10/10 Excellent

"Muy bien exelente"

[](https://expedia.ca/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information)

![HOTEL OSHO](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1_y.jpg)

### HOTEL OSHO

10/10 Excellent

"Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!"

[](https://expedia.ca/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information)

![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg)

### Camino Real Hotel

10/10 Excellent

"Excellent hotel, I willl always used it in this location "

[](https://expedia.ca/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information)

## Find out more about Santa Cruz

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Cruz. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

## Explore a world of travel with Expedia

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- [Apartments in Santa Cruz ](https://expedia.ca/Santa-Cruz-Apartments.d6053940-aaApartments.Travel-Guide-Accommodation)
- [Vacation Homes in Santa Cruz ](https://expedia.ca/Santa-Cruz-Private-Vacation-Homes.d6053940-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Aparthotels in Santa Cruz ](https://expedia.ca/Santa-Cruz-Apart-Hotels.d6053940-aaApartHotels.Travel-Guide-Accommodation)
- [Hostels in Santa Cruz ](https://expedia.ca/Santa-Cruz-Hostels.d6053940-aaHostels.Travel-Guide-Accommodation)
- [Condo Rentals in Santa Cruz ](https://expedia.ca/Santa-Cruz-Condos.d6053940-aaCondos.Travel-Guide-Accommodation)
- [Chalets in Santa Cruz ](https://expedia.ca/Santa-Cruz-Chalets.d6053940-aaChalets.Travel-Guide-Accommodation)
- [Lodges in Santa Cruz ](https://expedia.ca/Santa-Cruz-Lodges.d6053940-aaLodges.Travel-Guide-Accommodation)
- [Houseboats in Santa Cruz ](https://expedia.ca/Santa-Cruz-Houseboats.d6053940-aaHouseboats.Travel-Guide-Accommodation)
- [Inns in Santa Cruz ](https://expedia.ca/Santa-Cruz-Inns.d6053940-aaInns.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find a vacation rental in Santa Cruz?

### What are some of the best vacation home rentals in Santa Cruz?

> Downtown house JH.](https://www.expedia.ca/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) and [Jose Luis Noya](https://www.expedia.ca/Santa-Cruz-Hotels-Jose-Luis-Noya.h88272607.Hotel-Information).

### How many vacation rentals will I find in Santa Cruz?

### What can I see and do in Santa Cruz?

### What are vacation rentals like in Santa Cruz?

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