Santa Cruz Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*

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Your Santa Cruz Vacation

With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.

Ready to book your vacation to Santa Cruz?

 

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Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is CA $76 per night from Jul 28 to Jul 29
CA $76
CA $76 total
Jul 28 - Jul 29
9.4/10 Exceptional! (124 reviews)
"Good location and value for money."

Reviewed on May 23, 2026

Ibis Santa Cruz DE LA Sierra
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
The price is CA $179 per night from Jul 18 to Jul 19
CA $179
CA $179 total
Jul 18 - Jul 19
9/10 Wonderful! (386 reviews)
"Great property, in a very safe location that is close to good places to eat. Staff are very professional. Sr. Domingos who cooks the eggs at breakfast went above and beyond! All the pools are fantastic and the room wa large with a very, very comfortable bed. I would stay here again"

Reviewed on Jul 12, 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

4 out of 5
Av. San Martin, Calle 9 Este Santa Cruz
The price is CA $139 per night from Jul 15 to Jul 16
CA $139
CA $139 total
Jul 15 - Jul 16
9.2/10 Wonderful! (166 reviews)
"Good Hotel, nice to walk and Good Restaurants. In my room they have a problem with the design of the bathroom that they have to take care."

Reviewed on Jun 26, 2026

TRYP by Wyndham Santa Cruz
See all 298 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
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What to do in Santa Cruz

Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and the river

Private Tour of Santa Cruz: We visit the city center, Porongo, markets, and the river

CA $92
per adult
Private Tour of Santa Cruz: We visit the city center, Porongo, markets, and the river
The Che Guevara route is the most peculiar tourist destination in Bolivia.

4D/3N Expedition: Che Guevara Route - Disconnect from the World

CA $1,135
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
Fuerte de Samaipata, Bolivia

Samaipata Fort Tour: Ancient Ruins in 1 Full Day

CA $447
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Offering excellent value package deals on Expedia, you'll be surprised at how little a vacation to Santa Cruz costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Cruz?
If you're hoping to score a cheap Santa Cruz vacation package, consider planning a trip in February, April and May. You're likely to find lower prices on accommodations and flights during these months — ideal for travellers wishing to save money.
How many days is enough for Santa Cruz?
With a well-organized travel plan, you can easily tick off the most popular Santa Cruz attractions in a handful of days. But if you'd like to discover hidden spots or go on day trips, think about booking your Santa Cruz vacation for longer.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz is a good vacation destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're travelling with the family or planning a trip with friends, a Santa Cruz vacation promises fun for everyone.
How to find the best Santa Cruz package deals?
Begin your search for a Santa Cruz package deal by entering your destination and preferred travel dates under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Santa Cruz package deal right away, simply play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Cruz adventure off to a flying start.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customized Santa Cruz vacation by choosing your favourite type of stay, airline and car class.
When to book a vacation package to Santa Cruz?
If you're planning a spontaneous Santa Cruz getaway, browse our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can find terrific deals on your flights and hotels by booking ahead.
How to plan a trip to Santa Cruz?

  1. Choose your dates: What you'd like to do in Santa Cruz and your preferred season can help you decide when to travel.
  2. Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your hotel will likely be the largest expense during your trip to Santa Cruz.
  3. Decide your trip length: Think about how long you'd like to spend discovering Santa Cruz. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  4. Combine your accommodations and airfare: Once you've settled on your travel dates and duration, book the right Santa Cruz vacation package for you.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.