Santa Cruz Vacation Packages
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Your Santa Cruz Vacation
With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.
Santa Cruz Hotel Deals
Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is CA $76 per night from Jul 28 to Jul 29
CA $76
CA $76 total
Jul 28 - Jul 29
9.4/10 Exceptional! (124 reviews)
"Good location and value for money."
Reviewed on May 23, 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
The price is CA $179 per night from Jul 18 to Jul 19
CA $179
CA $179 total
Jul 18 - Jul 19
9/10 Wonderful! (386 reviews)
"Great property, in a very safe location that is close to good places to eat. Staff are very professional. Sr. Domingos who cooks the eggs at breakfast went above and beyond! All the pools are fantastic and the room wa large with a very, very comfortable bed. I would stay here again"
Reviewed on Jul 12, 2026
Sun Hotel
Av. Banzer Km 13 Santa Cruz Santa Cruz
The price is CA $153 per night from Jul 15 to Jul 16
CA $153
CA $153 total
Jul 15 - Jul 16
8.2/10 Very good! (386 reviews)
"I had arranged, as instructed by their website, to be picked up at the airport. I waited for one hour as I tried to call and tried to contact thru website/whatsApp- a no show! I showed them my online conversation reserving the free shuttle and they just shugged their shoulders- they are not reliable. ..."
Reviewed on Jul 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Cruz attractions
What to do in Santa Cruz
Private Tour of Santa Cruz: We visit the city center, Porongo, markets, and the river
CA $92
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
CA $1,135
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
CA $447
per adult
Frequently asked questions
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- Flights from Puerto Vallarta (PVR) to Santa Cruz (SRZ)
- Flights from Kelowna (YLW) to Santa Cruz (VVI)
- Flights from New York (JFK) to Santa Cruz (VVI)
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- Flights from Detroit (DTW) to Santa Cruz (VVI)
- Flights from Manila (MNL) to Santa Cruz (SRZ)
- Flights from Panama City (PTY) to Santa Cruz (VVI)
- Flights from Mexico City (MEX) to Santa Cruz (SRZ)
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- Flights from Cancun (CUN) to Santa Cruz (SRZ)
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- Flights from Toronto (YYZ) to Santa Cruz (SRZ)
- Flights from Norfolk (ORF) to Santa Cruz (SRZ)
- Flights from Palm Springs (PSP) to Santa Cruz (SRZ)
- Flights from San Cristobal (SCY) to Santa Cruz (VVI)
- Flights from Buffalo (BUF) to Santa Cruz (SRZ)
- Flights from Indianapolis (IND) to Santa Cruz (SRZ)
- Flights from Arica (ARI) to Santa Cruz (SRZ)
- Flights from Montreal (YUL) to Santa Cruz (SRZ)
- Flights from Toronto (YYZ) to Santa Cruz (VVI)
- Flights from Edmonton (YEG) to Santa Cruz (VVI)
- Flights from Raleigh (RDU) to Santa Cruz (SRZ)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
