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Sep 23 - Sep 24
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Sep 24 - Sep 25
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Sep 25 - Sep 27
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Oct 2 - Oct 4

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Our top choices for Sikeston Depot Museum hotels

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

1. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.4 km from Sikeston Depot Museum
United States
Allen
CA $142
CA $160 total
includes taxes & fees
Oct 4 - Oct 5
Fairfield Inn & Suites by Marriott Sikeston
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

2. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
2.3 km from Sikeston Depot Museum
United States
Stacy
CA $141
CA $159 total
includes taxes & fees
Oct 4 - Oct 5
TownePlace Suites by Marriott Sikeston
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

3. Hampton Inn Sikeston

Hampton Inn Sikeston
2.3 km from Sikeston Depot Museum
United States
John
CA $143
CA $162 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.
An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.
A kitchenette with a coffee machine, a kettle, and storage shelves.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.1 km from Sikeston Depot Museum
United States
michael
CA $142
CA $161 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express & Suites Sikeston Southwest by IHG
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

5. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
5.1 km from Sikeston Depot Museum
United States
Scott
CA $132
CA $152 total
includes taxes & fees
Sep 27 - Sep 28
Drury Inn & Suites Sikeston, MO
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

6. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
5.4 km from Sikeston Depot Museum
United States
Shelley
CA $123
CA $140 total
includes taxes & fees
Sep 27 - Sep 28
Best Western Plus Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
5 km from Sikeston Depot Museum
United States
Sharika West
CA $88
CA $100 total
includes taxes & fees
Sep 30 - Oct 1
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A living room with two sofas, a coffee table, a TV, and a cabinet.
A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

8. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
4.9 km from Sikeston Depot Museum
United States
Starlette
CA $126
CA $143 total
includes taxes & fees
Oct 14 - Oct 15
Comfort Inn & Suites Sikeston I-55
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious lobby with a central atrium, a piano, and a reception desk.

9. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
5.4 km from Sikeston Depot Museum
United States
David
CA $93
CA $106 total
includes taxes & fees
Oct 14 - Oct 15
Days Inn and Suites by Wyndham Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A motel with a covered entrance, multiple rooms, and a parking lot.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

10. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
4.7 km from Sikeston Depot Museum
United States
William
CA $80
CA $92 total
includes taxes & fees
Sep 29 - Sep 30
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A reception area with a counter, a coffee machine, and seating.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.
A bathroom with a bathtub, toilet, and shower curtain.

11. Country Yard Inn and Suite

Country Yard Inn and Suite
5.5 km from Sikeston Depot Museum
United States
William
CA $80
CA $95 total
includes taxes & fees
Sep 30 - Oct 1
Country Yard Inn and Suite
View all properties

Compare popular hotels close to Sikeston Depot Museum

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
Fairfield Inn & Suites by Marriott Sikeston
9.4
Exceptional
112 reviews
View
TownePlace Suites by Marriott Sikeston
9.4
Exceptional
26 reviews
View
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
Hampton Inn Sikeston
9.0
Wonderful
624 reviews
View
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
Holiday Inn Express & Suites Sikeston Southwest by IHG
8.8
Excellent
508 reviews
View
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
Drury Inn & Suites Sikeston, MO
9.6
Exceptional
1,000 reviews
View

Top Sikeston Depot Museum Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"."
Marcia 1-night trip
Posted 20 hours ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Staff was great"
Alex 2-night trip
Posted 21 hours ago
Hampton Inn Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Súper affordable pricing, and the property was clean and comfortable! Complimentary breakfast was a plus!"
Brianna 1-night trip
Posted 2 days ago
Super 8 by Wyndham Charleston/Sikeston East MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"This was a very good value. It has been the best hotel I've stayed at in awhile."
David 1-night trip
Posted 2 days ago
Days Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"The man at the front desk was very helpful and polite"
William 1-night trip
Posted 6 days ago
Super 8 by Wyndham Sikeston/Miner Area
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

10/10 Excellent
"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."
Stacy 2-night trip
Posted 6 days ago
TownePlace Suites by Marriott Sikeston
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

8/10 Good
"Overall it was excellant, other then the toilet running constantly... Pool could have been cleaner, considering the heat-wave they were having............."
Mark E 13-night trip
Posted 10 days ago
The Riverstone Hotel Charleston-Sikeston
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

10/10 Excellent
"We had an excellent stay here. The host was very nice and make sure that we had everything we needed. If we come back here, we will definitely try to get this house again.Needless to say, we were very pleased with our day."
Melissa W. 2-night trip
Posted 3 months ago
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Eagle Inn Charleston

Eagle Inn Charleston

10/10 Excellent
"Great"
Jackson 1-night trip
Posted 6 months ago
Eagle Inn Charleston

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Learn about the local history of Dexter when you take a trip to The Heritage House. While in this family-friendly area, you can enjoy the restaurants.
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Frequently asked questions

What's the area like around Sikeston Depot Museum?
Sikeston Depot Museum is located in a welcoming area of Sikeston known for its array of dining options. If you're looking for a convenient place to stay, check out the 5 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Sikeston Depot Museum?
Drury Inn & Suites Sikeston, MO is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located 3.2 mi (5.1 km) from Sikeston Depot Museum. Other good choices within 5 miles include Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston.
How many hotels should I expect to find close to Sikeston Depot Museum?
Expedia has 5 hotels and other accommodations within a mile from Sikeston Depot Museum.
If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Sikeston Depot Museum.

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