Murphysboro Vacation Rentals from CA $181: Short-Term Rentals for 2026

Q: What are some of the best vacation rentals in Murphysboro?

* On the Wine Trail * Hot Tub * Wi-Fi * : Visitors like this Murphysboro vacation home rental. It is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

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Our top choices for Murphysboro vacation rentals

A modern living room with a sectional sofa, a coffee table, a TV mounted on the wall, and a window with blinds.

1. The Lab! Come stay in our brand new space.

Murphysboro

Tim P.

CA $285 total

includes taxes & fees

Aug 28 - Aug 29

A large outdoor area with a pond, several wooden cabins, and a road.

2. Pet Friendly! Couples Retreat in Southern Illinois

Murphysboro

Stephen

CA $289 total

includes taxes & fees

Aug 30 - Aug 31

A wooden cabin with a front porch, a staircase, and a door.

3. Pet Friendly! Countryside Couples Stay in Illinois

Murphysboro

"We really enjoyed our stay overall. The location was excellent—quiet, peaceful, and set far enough away from town to avoid traffic, but still close enough to get anywhere quickly. The outdoor space was a big plus, especially for our dogs, who had plenty of room to roam. The beds were also very comfortable, which made for a great night’s sleep. The only downside was the cleanliness. The property was noticeably dusty, and the inside of the refrigerator could have been cleaned more thoroughly. With...

Jim P.

CA $332 total

includes taxes & fees

Aug 30 - Aug 31

4. Pet Friendly! Countryside Couples Stay in Illinois

Murphysboro

CA $324 total

includes taxes & fees

Sep 6 - Sep 7

A compact kitchen with a stone floor, a microwave, a stove, and a refrigerator. There are wooden cabinets and a window with blinds.

5. Fishing Cabin next to Kinkaid Lake

Murphysboro

Charles B.

CA $349 total

includes taxes & fees

Sep 3 - Sep 4

A spacious living room with hardwood flooring, a sofa, a chair, and a small table with a lamp.

6. Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

Oraville

Greg W.

CA $374 total

includes taxes & fees

Aug 28 - Aug 29

7. Cabin 2: Lakeside in Murphysboro

Murphysboro

Pamela S.

CA $332 total

includes taxes & fees

Sep 1 - Sep 2

A compact RV kitchen with wooden cabinets, a microwave, a stove, and a sink.

8. Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

Oraville

Joseph S.

CA $265 total

includes taxes & fees

Aug 28 - Aug 29

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Top Murphysboro Hotel Reviews

Baymont by Wyndham Marion

10/10 Excellent

"Nice rooms and beds. Good shower and water pressure. Good AC!"

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent

"The check in process was amazing. I expect a little southern hospitality in this part of the state, but they went above and beyond making sure that we picked the right rooms. There was a band "hinder" playing a concert in te let next to the hotel, which was actually really cool, but she made sure to ask us if that would bother us and even knew when they would stop. The room was very clean and taken care of, even though the features are dated. It lacks a thermostat and honestly has an older HVAC system. This means that the room was the perfect temperature, but there was a bit of dampness in the air. It would help to upgrade. But it didn't bother my sleeping and the bed was comfortable enough. Every staff member said "Hello" and did what they could to help. Freah cookies in the lobby were great. The breakfast was only so, so. I think that there is room for improvement here. Fresher food would be the place that I would start. Krispy Kreme is on your doorstep, make a deal. Also, in my humble opinion taking a look at how the coffee is made would not hurt, it might be a water filter that is needed. Not sure there. Over all, I would stay here again. If I were the corporate company or ownership, I would make sure that this general manager has everything that they need to make this property better. It's a true example of doing the best you can with what you have."

Find out more about Murphysboro

Everything you need to know about Murphysboro vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Murphysboro vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Murphysboro vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Murphysboro vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Murphysboro. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Murphysboro vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Murphysboro vacation rentals we have selected for you start as low as CA $181 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Murphysboro rentals

At Expedia, we put the best Murphysboro vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Murphysboro rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Murphysboro vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Murphysboro. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Murphysboro?

Yes, there are vacation rentals near the most popular points of interest in Murphysboro, or you can select a secluded option if you'd like a relaxing place to stay. Murphysboro is known for its restaurants and golf courses. Make sure you have time to check out the parks and museums during your trip.

What are some of the best vacation rentals in Murphysboro?

* On the Wine Trail * Hot Tub * Wi-Fi *: Visitors like this Murphysboro vacation home rental. It is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

How many vacation rentals are there in Murphysboro?

Choose from 17 Expedia vacation rentals in Murphysboro for a memorable vacation.

What’s there to see and do in Murphysboro?

Shawnee National Forest and Kinkaid Lake are a couple of scenic spots to enjoy the outdoors, whereas General John A. Logan Museum is one of the cultural attractions. Other places in town to visit include Hickory Ridge Public Golf Center and Lake Murphysboro State Park.

What’s a vacation rental in Murphysboro like?

A vacation rental is a private property you can book for short or long periods in Murphysboro. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can offer a sense of safety away from shared hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips.

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Our top choices for Murphysboro vacation rentals

1. The Lab! Come stay in our brand new space.

2. Pet Friendly! Couples Retreat in Southern Illinois

3. Pet Friendly! Countryside Couples Stay in Illinois

4. Pet Friendly! Countryside Couples Stay in Illinois

5. Fishing Cabin next to Kinkaid Lake

6. Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

7. Cabin 2: Lakeside in Murphysboro

8. Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

9. Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

10. Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

11. Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

12. Stylish Queen Suite Near SIU Carbondale

13. Pine Cabin #2 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

14. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

15. Hot Tub Cabin- In the Heart of Shawnee Wine Trail

16. Romantic Cabin w/ Hot Tub Near Carbondale

17. Experience Glamping in style. Private Hot tub spa! Private lake -Pet Friendly

18. Modern 2BR Cabin w/ Hot Tub Near Carbondale

19. Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

20. Experience Glamping in style. Private Lake - Pet Friendly!

Find vacation rentals that suit your style

Top Murphysboro Hotel Reviews

Baymont by Wyndham Marion

Home2 Suites by Hilton Carbondale

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Carbondale - University Area by IHG

Country Inn & Suites by Radisson, Marion, IL

Hampton Inn Carbondale

Pet Friendly! Couples Retreat in Southern Illinois

Find out more about Murphysboro

Frequently asked questions

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