Title: Murphysboro Vacation Packages & Trips 2026 | Expedia.ca [Hotels in Murphysboro](https://expedia.ca/Murphysboro-Hotels.d55857.Travel-Guide-Hotels)[Vacation Rentals in Murphysboro](https://expedia.ca/Murphysboro-Vacation-Rentals.d55857.Travel-Guide-VacationRentals)[Murphysboro Car Rentals](https://expedia.ca/Car-Rentals-In-Murphysboro.d55857.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6186677/653cb0cf-de6f-4f9e-a73f-18858257194c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Murphysboro Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings Photo by Southernmost Illinois Tourism Bureau - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place #### Your Murphysboro Vacation Amazing adventures await when you reserve a Murphysboro vacation package. Whether you're a foodie, art buff or just a traveler who loves to see new places, there's something for everyone in this vibrant city. [Lake Murphysboro State Park](https://www.expedia.ca/Lake-Murphysboro-State-Park-Murphysboro.d6186677.Vacation-Attraction), [Hickory Ridge Public Golf Center](https://www.expedia.ca/Hickory-Ridge-Public-Golf-Center-Illinois.d6183574.Vacation-Attraction) and [General John A. Logan Museum](https://www.expedia.ca/General-John-A-Logan-Museum-Murphysboro.d6186673.Vacation-Attraction) are just a few of the many sights you'll want to explore during your trip to Murphysboro. A couple of quick clicks is all it takes to craft the perfect Murphysboro vacation on Expedia. ## Ready to book your vacation to Murphysboro? Choose your dates ## Murphysboro Hotel Deals ![Holiday Inn Express & Suites Murphysboro - Carbondale by IHG](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/cb237759_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG 120 MUDDY MONSTER ROAD Murphysboro IL Fully refundable CA $169 CA $187 total Mar 29 - Mar 30 includes taxes & fees 9.4/10 Exceptional! (532 reviews) Staff are super nice, helpful, and friendly! Breakfast was always great, good selection to choose from. Its clean and quiet, a perfect home away from home couldn't be happer! Reviewed on Mar 15, 2026 [](https://expedia.ca/Hotel-Search?startDate=29%2F03%2F2026&endDate=30%2F03%2F2026&selected=63308723&PinnedHotelID=63308723&HadPinnedHotel=true®ionId=55857) ![On the Lake & Wine Trail & a Perfect Getaway for 16+ With an ADA Suite!](https://images.trvl-media.com/lodging/75000000/74790000/74786000/74785961/a8895248_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### On the Lake & Wine Trail & a Perfect Getaway for 16+ With an ADA Suite! Murphysboro IL 10/10 Exceptional! (16 reviews) We had a lovely stay! The space was perfect for our family gathering. Our host was very responsive and welcoming. The home has a great location and we were able to enjoy some lovely hikes in the Shawnee and delicious BBQ in Murphysboro! Reviewed on Dec 29, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=08%2F04%2F2026&endDate=09%2F04%2F2026&selected=74785961&PinnedHotelID=74785961&HadPinnedHotel=true®ionId=55857) [](https://expedia.ca/Hotel-Search?startDate=08%2F04%2F2026&endDate=09%2F04%2F2026&selected=74785961&PinnedHotelID=74785961&HadPinnedHotel=true®ionId=55857) ![5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING](https://images.trvl-media.com/lodging/93000000/92480000/92471400/92471349/b1e717c7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING Murphysboro IL 10/10 Exceptional! (21 reviews) The host was very informative and shared any information we would need. She was quick to respond when we had a question.The cabin is an excellent place to sit back and relax. Had everything we needed. We actually looked to book again for the summer so we could enjoy the pond and pool. Everything ... Reviewed on Feb 6, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=08%2F04%2F2026&endDate=09%2F04%2F2026&selected=92471349&PinnedHotelID=92471349&HadPinnedHotel=true®ionId=55857) [](https://expedia.ca/Hotel-Search?startDate=08%2F04%2F2026&endDate=09%2F04%2F2026&selected=92471349&PinnedHotelID=92471349&HadPinnedHotel=true®ionId=55857) [See all 335 properties in Murphysboro](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=26%2F03%2F2026&endDate=27%2F03%2F2026®ionId=55857) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app