Title: Murphysboro Vacation Rentals from CA $154: Short-Term Rentals for 2026 | Expedia.ca

[Hotels in Murphysboro](https://expedia.ca/Murphysboro-Hotels.d55857.Travel-Guide-Hotels)[Murphysboro Car Rentals](https://expedia.ca/Car-Rentals-In-Murphysboro.d55857.Car-Rental-Guide)[Murphysboro Vacation Packages](https://expedia.ca/Murphysboro.d55857.Destination-Travel-Guides)

![Lake Murphysboro State Park which includes autumn leaves, picnicing and forests](https://images.trvl-media.com/place/6186677/108d6e6a-45bc-4623-a9ba-f3146d9aa969.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Southernmost Illinois Tourism Bureau

![](https://images.trvl-media.com/place/6186677/108d6e6a-45bc-4623-a9ba-f3146d9aa969.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 19 - Jun 21](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 17 - Jul 19](https://www.expedia.ca/Hotel-Search?regionId=55857&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Murphysboro vacation rentals

![House (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/aa6e717a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/3ac16db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/02464d31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/3ed90f05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pet Friendly! Countryside Couples Stay in Illinois

[](https://www.expedia.ca/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

Murphysboro

CA $134

CA $327 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08&regionId=55857&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CABIN)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=COTTAGE)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APARTMENT)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CONDO)

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## Top Murphysboro Hotel Reviews

![Best Western Saluki Inn](https://images.trvl-media.com/lodging/1000000/120000/119200/119178/43576f21_y.jpg)

### Best Western Saluki Inn

10/10 Excellent

"Very welcoming I got some great rest. Very clean as well! Enjoyed remodeled pool very much!"

[](https://expedia.ca/Carbondale-Hotels-Best-Western-Saluki-Inn.h119178.Hotel-Information)

![Best Western Marion Hotel](https://images.trvl-media.com/lodging/1000000/100000/98000/97975/86964c5d_y.jpg)

### Best Western Marion Hotel

8/10 Good

"Excellent value!"

[](https://expedia.ca/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information)

![Hampton Inn Carbondale](https://images.trvl-media.com/lodging/1000000/480000/479200/479116/e725ca3d_y.jpg)

### Hampton Inn Carbondale

6/10 Okay

"I’m upset because I booked this hotel for the pool specifically and it was under maintenance which id only found out after checking in. I didn’t stay there for the rest of the night, but I was clean."

[](https://expedia.ca/Carbondale-Hotels-Hampton-Inn-Carbondale.h479116.Hotel-Information)

![Holiday Inn Carbondale-Conference Center by IHG](https://images.trvl-media.com/lodging/2000000/1490000/1489300/1489254/189476cd_y.jpg)

### Holiday Inn Carbondale-Conference Center by IHG

10/10 Excellent

"My stay was amazing. Rooms were clean and up kept. The property was quite and well kept. The staff was awesome two thumbs up for them"

[](https://expedia.ca/Carbondale-Hotels-Holiday-Inn-Carbondale-Conference-Center.h1489254.Hotel-Information)

![Home2 Suites by Hilton Carbondale](https://images.trvl-media.com/lodging/23000000/22420000/22413300/22413272/6cc7da21_y.jpg)

### Home2 Suites by Hilton Carbondale

2/10 Terrible

"Parking was horrendous/non-existent. Noise around the hotel was terrible. There is only one elevator in the center of the building so depending on where your room is and where you park, you might end up walking really far to your room and then back and forth to your car...nightmare. Upon entering the room, a foul odor. Dishwasher was rancid. That got better after we ran it. Garbage disposal didn't work and was full of rotten food. "

[](https://expedia.ca/Carbondale-Hotels-Home2-Suites-By-Hilton-Carbondale.h22413272.Hotel-Information)

![Holiday Inn Express Hotel & Suites Marion Northeast by IHG](https://images.trvl-media.com/lodging/5000000/4980000/4970900/4970883/cbf733c6_y.jpg)

### Holiday Inn Express Hotel & Suites Marion Northeast by IHG

10/10 Excellent

"Wonderful breakfast! Not complimentary but plenty to choose from. Very convenient start to the day. "

[](https://expedia.ca/Carbondale-Hotels-Holiday-Inn-Express-Hotel-Suites-Marion-Northeast.h4970883.Hotel-Information)

![Comfort Inn & Suites Marion I-57](https://images.trvl-media.com/lodging/6000000/5160000/5156200/5156103/ff67b3f4_y.jpg)

### Comfort Inn & Suites Marion I-57

10/10 Excellent

"Good breakfast"

[](https://expedia.ca/Carbondale-Hotels-Comfort-Inn-Suites-Marion-I-57.h5156103.Hotel-Information)

![Baymont by Wyndham Marion](https://images.trvl-media.com/lodging/1000000/20000/19300/19275/7eb84743_y.jpg)

### Baymont by Wyndham Marion

4/10 Poor

"Our biggest issue was the air conditioning barely worked. It was very hot in the room, even when I set the AC to 60\. The shower had stains, the trim was loose on the faucets, our pillows did not smell like they had been cleaned, and the staff when we checked in was very short with us and not personalable. And the lady when we checked out couldn’t pull her nose from her phone long enough to hear of our issues. The list goes on, but we will not be staying there again. "

[](https://expedia.ca/Carbondale-Hotels-Baymont-By-Wyndham-Marion.h19275.Hotel-Information)

![Country Inn & Suites by Radisson, Marion, IL](https://images.trvl-media.com/lodging/3000000/2460000/2457400/2457332/6bf09f9e_y.jpg)

### Country Inn & Suites by Radisson, Marion, IL

8/10 Good

"Let me start with the staff here is amazing! However it is right off the main road so you can hear the road noise at night. The breakfast was ok nothing amazing. The room was very clean big and the bed was super comfortable. We had some problems with the TV but the front desk lady helped us out with no problems, minor issue. Now this is absolutely not the hotel or staff’s fault but we could hear the TV in the room next to us all night. Then at 230 AM, yes AM there was some people who checked with loud children running up & down the hallways yelling or maybe the adults just didn’t care that they are the reason they raised horrible ungrateful heathens that have no consideration of other people sleeping. "

[](https://expedia.ca/Carbondale-Hotels-Country-Inn-Suites-By-Radisson.h2457332.Hotel-Information)

## Find out more about Murphysboro

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Murphysboro. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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- [Vacation Homes in Murphysboro ](https://expedia.ca/Murphysboro-Private-Vacation-Homes.d55857-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cabin Rentals in Murphysboro ](https://expedia.ca/Murphysboro-Cabins.d55857-aaCabins.Travel-Guide-Accommodation)
- [RV Parks in Murphysboro ](https://expedia.ca/Murphysboro-RV-Parks.d55857-aaRVParks.Travel-Guide-Accommodation)
- [Apartments in Murphysboro ](https://expedia.ca/Murphysboro-Apartments.d55857-aaApartments.Travel-Guide-Accommodation)
- [Motels in Murphysboro ](https://expedia.ca/Murphysboro-Motels.d55857-aaMotels.Travel-Guide-Accommodation)
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- [Farmstay in Murphysboro ](https://expedia.ca/Murphysboro-Agritourism.d55857-aaAgritourism.Travel-Guide-Accommodation)
- [B&B in Murphysboro ](https://expedia.ca/Murphysboro-Bed-And-Breakfast.d55857-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Lodges in Murphysboro ](https://expedia.ca/Murphysboro-Lodges.d55857-aaLodges.Travel-Guide-Accommodation)
- [Guest Houses in Murphysboro ](https://expedia.ca/Murphysboro-Guest-Houses.d55857-aaGuestHouses.Travel-Guide-Accommodation)
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## Frequently asked questions

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