Murphysboro Vacation Rentals from CA $123: Short-Term Rentals for 2026

Q: What are some of the best vacation rentals in Murphysboro?

* On the Wine Trail * Hot Tub * Wi-Fi * : Visitors like this Murphysboro vacation home rental. It is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

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Our top choices for Murphysboro vacation rentals

A modern living room with a sectional sofa, a coffee table, a TV mounted on the wall, and a window with blinds.

1. The Lab! Come stay in our brand new space.

Murphysboro

Tim P.

CA $276 total

includes taxes & fees

Nov 10 - Nov 11

A compact kitchen with a stone floor, a microwave, a stove, and a refrigerator. There are wooden cabinets and a window with blinds.

2. Fishing Cabin next to Kinkaid Lake

Murphysboro

Dustin M.

CA $339 total

includes taxes & fees

Nov 14 - Nov 15

A room with a black tufted sofa, two armchairs, a gold coffee table, a patterned rug, a wall-mounted ladder decor, and a framed inspirational quote.

3. The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit

Murphysboro

"Place overall was decent, it was clean enough. The hot tub and fire pit were a nice touch. The house is very close to the road and there is constant traffic noise even late at night. It is also advertised as more upscale than it was. We noticed several areas of the house that looked like the landlord special took place in getting it ready. Some of the doors didn’t close properly or were only on a single set of hinges instead of multiple. The dining chairs too were not in great shape, they had...

Calista

CA $320 total

includes taxes & fees

Dec 2 - Dec 3

A large outdoor area with a pond, several wooden cabins, and a road.

4. Pet Friendly! Couples Retreat in Southern Illinois

Murphysboro

CA $329 total

includes taxes & fees

Nov 15 - Nov 16

5. Cabin 2: Lakeside in Murphysboro

Murphysboro

Pamela S.

CA $329 total

includes taxes & fees

Nov 9 - Nov 10

A wooden cabin with a front porch, a staircase, and a door.

6. Pet Friendly! Countryside Couples Stay in Illinois

Murphysboro

"We really enjoyed our stay overall. The location was excellent—quiet, peaceful, and set far enough away from town to avoid traffic, but still close enough to get anywhere quickly. The outdoor space was a big plus, especially for our dogs, who had plenty of room to roam. The beds were also very comfortable, which made for a great night’s sleep. The only downside was the cleanliness. The property was noticeably dusty, and the inside of the refrigerator could have been cleaned more thoroughly. With...

Jim P.

CA $325 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen with white cabinets, a central island, and a stone fireplace.

7. Minutes from Lake |Fire Pit | Like-New 3BR Retreat

Murphysboro

Scott M.

CA $616 total

includes taxes & fees

Nov 13 - Nov 14

A spacious living room with hardwood flooring, a sofa, a chair, and a small table with a lamp.

8. Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

Oraville

Greg W.

CA $244 total

includes taxes & fees

Nov 13 - Nov 14

9. Pet Friendly! Couples Retreat in Southern Illinois

Murphysboro

Stephen

CA $322 total

includes taxes & fees

Nov 16 - Nov 17

10. Pet Friendly! Countryside Couples Stay in Illinois

Murphysboro

CA $348 total

includes taxes & fees

Dec 3 - Dec 4

A recreational vehicle with a covered living area, a small porch, and a wooden deck.

11. Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

Oraville

Kevin E.

CA $177 total

includes taxes & fees

Nov 9 - Nov 10

A cozy cabin interior with a stone fireplace, wooden walls, and various framed pictures.

12. Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

Carbondale

Travis S.

A living room with two beige sofas, a marble coffee table, and striped curtains.

13. Located in the Luxurious Pine Manor Estates!

Carbondale

adaire p.

CA $517 total

includes taxes & fees

Dec 1 - Dec 2

14. Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

Makanda

Kevin W.

CA $192 total

includes taxes & fees

Nov 15 - Nov 16

A compact RV kitchen with wooden cabinets, a microwave, a stove, and a sink.

15. Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

Oraville

Joseph S.

CA $201 total

includes taxes & fees

Nov 9 - Nov 10

A wooden cabin with a green door, a number '2' sign, a small porch with a wooden railing, and a wall-mounted lantern.

16. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

Makanda

Alison K.

CA $257 total

includes taxes & fees

Nov 9 - Nov 10

A hotel room with a bed, bedside table, lamp, and a mirror on the wall.

17. Peaceful, Comfy and Pet Friendly 2-bedroom home in Quiet Makanda

Makanda

Debrasues M.

CA $178 total

includes taxes & fees

Nov 15 - Nov 16

A wooden deck with a table and chairs, leading to a building with a window and a wall-mounted light fixture.

18. Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi

Makanda

Teal B.

CA $259 total

includes taxes & fees

Nov 16 - Nov 17

A deck with a fire pit surrounded by rocks, two chairs, and a view of a forested area.

19. Pine Cabin #2 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

Carbondale

Rocco C.

A compact kitchen with wooden walls, a built-in oven, a sink, and a refrigerator.

20. The Cozy Corner

De Soto

yvonne o.

CA $187 total

includes taxes & fees

Nov 15 - Nov 16

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Find vacation rentals that suit your style

Top Murphysboro Hotel Reviews

A modern restaurant with high tables and orange chairs, a bar area, and large windows with a view.

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

10/10 Excellent

JUNWOO

A modern dining area with round tables and chairs, large windows, and a chandelier.

Holiday Inn Express & Suites Carbondale - University Area by IHG

Carbondale

8/10 Good

Marie

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

Home2 Suites by Hilton Carbondale

Carbondale

10/10 Excellent

Clean, spacious suite, excellent kitchen (talk to front desk staff for induction cooktop). Loved the breakfast bar options that shifted daily. Property is secure 24/7, which was a nice detail. Minor qualm was the saline pool spent about 40% of my stay as being closed - seemed to have some challenges with it, but definitely not a deal breaker. And the suites have the best blackout blinds I've ever encountered in a hotel! Will def stay again.

Jillian

A hotel entrance with a 'Welcome' sign and a 'Hampton Inn' sign.

Hampton Inn Carbondale

Carbondale

10/10 Excellent

Anonymous traveller

A hotel room with two beds, a desk, a chair, a TV, a lamp, and a painting on the wall.

Best Western Saluki Inn

Carbondale

10/10 Excellent

Jacqueline

A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

Country Inn & Suites by Radisson, Marion, IL

Marion

10/10 Excellent

Shannon

A hotel room with a large framed picture of a tree on the wall, a neatly made bed with white bedding, and two bedside lamps.

Super 8 by Wyndham Carbondale

Carbondale

10/10 Excellent

James

A bathroom with a bathtub, a sink, and a mirror.

Americas Best Value Inn West Frankfort

West Frankfort

8/10 Good

ann-Marie

A reception area with a counter, a plant, and a sign that says "Please ring for service."

Laketree Inn And Suites Marion

Marion

8/10 Good

Stacey

Find out more about Murphysboro

Everything you need to know about Murphysboro vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Murphysboro vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Murphysboro vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Murphysboro vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Murphysboro. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Murphysboro vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Murphysboro vacation rentals we have selected for you start as low as CA $123 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Murphysboro rentals

At Expedia, we put the best Murphysboro vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Murphysboro rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Murphysboro vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Murphysboro. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Are there vacation rentals in Murphysboro?

Yes, there are vacation rentals near the most popular points of interest in Murphysboro, or you can select a secluded option if you'd like a relaxing place to stay. Murphysboro is known for its restaurants and golf courses. Make sure you have time to check out the parks and museums during your trip.

What are some of the best vacation rentals in Murphysboro?

* On the Wine Trail * Hot Tub * Wi-Fi *: Visitors like this Murphysboro vacation home rental. It is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

How many vacation rentals are there in Murphysboro?

Choose from 17 Expedia vacation rentals in Murphysboro for a memorable vacation.

What’s there to see and do in Murphysboro?

Shawnee National Forest and Kinkaid Lake are a couple of scenic spots to enjoy the outdoors, whereas General John A. Logan Museum is one of the cultural attractions. Other places in town to visit include Lake Murphysboro State Park and Hickory Ridge Public Golf Center.

What’s a vacation rental in Murphysboro like?

A vacation rental is a private property you can book for short or long periods in Murphysboro. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can offer a sense of safety away from shared hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips.

Murphysboro Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Murphysboro vacation rentals

1. The Lab! Come stay in our brand new space.

2. Fishing Cabin next to Kinkaid Lake

3. The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit

4. Pet Friendly! Couples Retreat in Southern Illinois

5. Cabin 2: Lakeside in Murphysboro

6. Pet Friendly! Countryside Couples Stay in Illinois

7. Minutes from Lake |Fire Pit | Like-New 3BR Retreat

8. Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

9. Pet Friendly! Couples Retreat in Southern Illinois

10. Pet Friendly! Countryside Couples Stay in Illinois

11. Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

12. Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

13. Located in the Luxurious Pine Manor Estates!

14. Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

15. Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

16. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

17. Peaceful, Comfy and Pet Friendly 2-bedroom home in Quiet Makanda

18. Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi

19. Pine Cabin #2 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

20. The Cozy Corner

Find vacation rentals that suit your style

Top Murphysboro Hotel Reviews

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent

Find out more about Murphysboro

Murphysboro vacation rentals: An excellent choice for every season

How to find incredible deals on Murphysboro rentals

Frequently Asked Questions

Are there vacation rentals in Murphysboro?

What are some of the best vacation rentals in Murphysboro?

How many vacation rentals are there in Murphysboro?

What’s there to see and do in Murphysboro?

What’s a vacation rental in Murphysboro like?