The 10 Best Hotels Near Mayo Clinic, Rochester from CA $112

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Our top choices for Mayo Clinic hotels

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.

A hotel room with a large bed, a desk, a chair, a microwave, and a framed picture on the wall.

A banquet hall with round tables, chairs, chandeliers, and a fireplace.

A hotel entrance with a modern design, large windows, and a sign indicating it's a Grand Hotel.

1. Kahler Grand Hotel

Downtown Rochester, 0.1 km from Mayo Clinic

Carew

CA $186

CA $215 total

includes taxes & fees

Sep 17 - Sep 18

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

A restaurant with a bar area, wooden chairs, and a stone wall.

A hotel room with a sofa, two beds, a large window, and a framed artwork on the wall.

A reception area with a wooden reception desk, a clock, and a wall-mounted display.

2. Kahler Inn and Suites - Mayo Clinic Area

Downtown Rochester, 0.2 km from Mayo Clinic

Greg

CA $199

CA $229 total

includes taxes & fees

Sep 19 - Sep 20

A modern lobby with a reception desk, a green sofa, and a black spherical table.

A modern hotel with a prominent 'Hotel Indigo' sign, a 'Crave Drink' restaurant, and a well-lit facade.

A modern bar area with a central island, bar stools, and hanging spherical light fixtures.

An indoor dining area with wooden ceiling beams, large windows, and modern furniture.

3. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 0.4 km from Mayo Clinic

Kyle

CA $149

CA $171 total

includes taxes & fees

Sep 25 - Sep 26

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A garden with a water feature, rocks, and yellow umbrellas.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

4. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 0.6 km from Mayo Clinic

Carrie

CA $150

CA $173 total

includes taxes & fees

Sep 19 - Sep 20

A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.

A modern hotel lobby with a curved staircase, seating areas, and large windows.

A spacious lobby with modern furniture, a spiral staircase, and large windows offering views of the outdoors.

A modern hotel entrance with a glass facade, illuminated signage, and a covered walkway.

5. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 0.3 km from Mayo Clinic

Jennifer

CA $250

CA $287 total

includes taxes & fees

Sep 25 - Sep 26

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern indoor pool area with lounge chairs and a pool.

A modern bar area with seating and a counter.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

6. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 0.5 km from Mayo Clinic

Kathy

CA $164

CA $189 total

includes taxes & fees

Oct 3 - Oct 4

A modern indoor patio with a fire feature, seating, and large windows.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1 km from Mayo Clinic

Brooke

CA $170

CA $214 total

includes taxes & fees

Sep 19 - Sep 20

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel room with a bed, bedside table, and a window with curtains.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

8. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 0.4 km from Mayo Clinic

Hafsa

CA $190

CA $219 total

includes taxes & fees

Sep 25 - Sep 26

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A reception area with a curved counter, ceiling lights, and a potted plant.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

9. Brentwood Inn & Suites

Downtown Rochester, 0.3 km from Mayo Clinic

Delton

CA $130

CA $150 total

includes taxes & fees

Sep 17 - Sep 18

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

A reception area with two counters, a patterned wall, and a wooden floor.

10. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 0.3 km from Mayo Clinic

BRIAN

CA $170

CA $195 total

includes taxes & fees

Sep 25 - Sep 26

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

11. The Berkman

Folwell, 1.4 km from Mayo Clinic

Kathleen

CA $234

CA $272 total

includes taxes & fees

Sep 19 - Sep 20

A modern building with large glass windows and indoor plants.

A modern hotel lobby with a large dining table, wicker chairs, a sofa, and a hanging green plant.

A modern living room with a beige leather sofa, two wooden coffee tables, and a large window with sheer curtains.

A clean, well-lit food service area with a 'Market To Go!' sign, refrigerated display cases, and a variety of packaged goods.

12. Marriott Rochester Mayo Clinic

Downtown Rochester, 0.2 km from Mayo Clinic

Jeff

CA $290

CA $334 total

includes taxes & fees

Sep 18 - Sep 19

An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.

A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

A hotel room with two beds, a desk, a chair, a television, and a window with curtains.

13. Med City Inn & Suites - Mayo Clinic Area

Kutzky Park, 1.6 km from Mayo Clinic

Jose

CA $99

CA $114 total

includes taxes & fees

Sep 17 - Sep 18

An outdoor terrace with tables and chairs, a large umbrella, and a view of a modern building with string lights.

A hotel reception area with a curved reception desk, a refrigerator stocked with snacks, a vending machine, and a large abstract painting on the wall.

A modern kitchen with stainless steel appliances, a built-in oven, and a variety of food items on the counter.

A modern hotel room with a fireplace, a sofa, a TV, and a large window with curtains.

14. Residence Inn by Marriott Rochester Mayo Clinic Area

Downtown Rochester, 0.2 km from Mayo Clinic

Greg

CA $221

CA $255 total

includes taxes & fees

Oct 2 - Oct 3

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A modern interior with a dining area, a kitchen, and a pantry stocked with snacks.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

15. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1 km from Mayo Clinic

matthew

CA $164

CA $192 total

includes taxes & fees

Oct 1 - Oct 2

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

A hotel entrance with a prominent Aspen sign, a large brick building in the background, and a clear sky.

16. Aspen Suites

1.2 km from Mayo Clinic

Dr. suzette

CA $197

CA $239 total

includes taxes & fees

Sep 18 - Sep 19

A lobby with leather chairs, a reception desk, a TV, and a coffee station.

An outdoor patio with tables and chairs, a sign for Aspen Suites, and a building in the background.

A hotel with a modern building featuring a prominent sign, a covered entrance, and a parking area.

A restaurant with tables and chairs, a trash bin, a coffee machine, and a television displaying a sports game.

17. Aspen Select

Kutzky Park, 1.2 km from Mayo Clinic

Ashley

CA $175

CA $212 total

includes taxes & fees

Sep 20 - Sep 21

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

A hotel reception desk with a modern design, a clock, and a digital screen.

A modern hotel room with a large bed, two bedside tables, and built-in lighting.

A modern conference room with a long table, multiple chairs, and a wooden partition.

18. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park, 1.1 km from Mayo Clinic

Breeanna

CA $136

CA $157 total

includes taxes & fees

Sep 25 - Sep 26

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A gym with exercise equipment, a clock, and a window with blinds.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

19. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 1.4 km from Mayo Clinic

Lin

CA $158

CA $182 total

includes taxes & fees

Oct 3 - Oct 4

View all properties

Compare popular hotels close to Mayo Clinic

Property	Star rating	Guest rating
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 739 reviews	View
The Berkman	9.6 Exceptional 438 reviews	View
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,004 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 560 reviews	View
Residence Inn by Marriott Rochester Mayo Clinic Area South	9.6 Exceptional 306 reviews	View

Top Mayo Clinic Hotel Reviews

Hilton Rochester Mayo Clinic Area

10/10 Excellent

"Super nice and helpful staff from the moment we arrived. If there for Mayo clinic they provide rides to appointments ( and for people not there for Mayo too) rooms were very clean and comfortable pool and hot tub were awesome close to restaurants and shops. will stay again"

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"The staff was very friendly and helpful. Monday Sept 15th was pretty hectic in the afternoon and the staff handled it seamlessly. The room was clean and stocked. We'll be back."

Kahler Grand Hotel

8/10 Good

"Glad the parking ramp was re-opened. One elevator was broke and the others were slow. Otherw use, the room was nice and comfortable."

Hilton Garden Inn Rochester Downtown, MN

10/10 Excellent

"Property is great, ez access to all mayo facilities using the skywalk and or subway. Weather was beautiful so we walked outside to Mayo/Gonda building which is a couple of blocks.We also utilized the free shuttle to an appointment, great perk. Excellent food choices within walking distance. Would definitely stay again."

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"Great rooms and great location. Thanks, Chris"

The Berkman

8/10 Good

"The ambiance, location, staff were all fantastic! The room was very clean and well setup. We liked everything except for the chairs in front of the tv. We would have preferred something a little more comfortable, preferably a small couch or a chair one can sink into."

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"Clean room"

Aspen Select

8/10 Good

"It was a very pleasant one night stay. I would recommend this hotel, nothing fancy, but reasonably priced, very friendly staff. And perfect location for Mayo outpatient surgery."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent

"Clean rooms and helpful staff. A great place to rest after a long day!"

Frequently asked questions

What are the top-rated hotels near Mayo Clinic?

Discovering the top-rated hotels near Mayo Clinic ensures a comfortable and convenient stay during your visit to Rochester, Minnesota.Home2 Suites by Hilton Rochester Mayo Clinic AreaHome2 Suites by Hilton Rochester Mayo Clinic Area is a welcoming 3-star hotel located just 4.5 km from Mayo Clinic, rated 9.6 by travellers. Guests appreciate the modern amenities, including a kitchenette with a dishwasher and microwave, as well as a cozy sofa bed. The hotel features complimentary daily breakfast and an accessible indoor pool, making it a perfect choice for those seeking a relaxed atmosphere. With additional perks like Egyptian cotton sheets and a fitness centre, this hotel ensures comfort and convenience for every traveler.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott Rochester Mayo Clinic Area South is another excellent option, situated 4.5 km from Mayo Clinic and a review rating of 9.6. This 3-star hotel offers spacious rooms with full kitchens and a convenient wet bar, ideal for longer stays. Guests can enjoy a complimentary breakfast and take advantage of the indoor pool and hot tub. The fitness centre is accessible 24 hours, ensuring travellers can maintain their routine while away from home.Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysFairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys is perfectly located just 2.4 km from Mayo Clinic, earning an impressive review rating of 9.6. This hotel features comfortable suites and an inviting atmosphere, complete with an indoor pool and a rooftop garden for relaxation. Guests can enjoy complimentary breakfast and easy access to an onsite tennis court, making it a great choice for those looking to stay active during their visit.

What hotels are within walking distance to Mayo Clinic?

Discover the convenience of top-rated hotels within walking distance to Mayo Clinic, perfect for travellers seeking comfort and accessibility.Hilton Rochester Mayo Clinic AreaHilton Rochester Mayo Clinic Area is a welcoming 3.5-star hotel located just a 6-minute walk from Mayo Clinic, with an impressive review rating of 9.6. This hotel features an indoor pool, a full-service spa offering massages and aromatherapy treatments, and a fitness centre open 24 hours. Guests can also enjoy relaxing moments in the hot tub and steam room, making it an excellent choice for relaxation after a day at the clinic.TownePlace Suites by Marriott Rochester Mayo Clinic AreaTownePlace Suites by Marriott Rochester Mayo Clinic Area is a cozy 3-star hotel that is only a 5-minute stroll from Mayo Clinic, rated 9.6 by travellers. It offers a complimentary buffet breakfast and 24-hour fitness facilities. Guests appreciate the rooftop garden and the convenience of in-room kitchens, perfect for those looking to prepare their own meals. The hotel also provides free area shuttle services, adding to its overall convenience for travellers.Staybridge Suites Rochester - Mayo Clinic Area by IHGStaybridge Suites Rochester - Mayo Clinic Area by IHG is a comfortable 3-star hotel located a 12-minute walk from Mayo Clinic, with a solid review rating of 9.4. This hotel features an indoor pool and a hot tub, along with spacious suites equipped with kitchens and premium bedding. Guests can enjoy a complimentary breakfast daily and take advantage of the free area shuttle service, making it an ideal base for those visiting the clinic.

How much is a hotel near Mayo Clinic?

Staying near Mayo Clinic is a treat, with plenty of hotels from CA $112 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during weekends or around public holidays.

What are the most popular family-friendly hotels near Mayo Clinic?

For families visiting Mayo Clinic, finding the perfect family-friendly hotel is essential for a comfortable stay. Here are some of the top-rated options that cater to families.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaLocated just an 8-minute walk from Mayo Clinic, the Centerstone Plaza Hotel Soldiers Field is a family-friendly haven with a review rating of 8.4 and a 3-star rating. This hotel features an indoor pool with a children's area, free daily breakfast, and kitchens in select rooms, perfect for families. Guests will appreciate the comfortable accommodations and easy access to the clinic.Med City Inn & Suites - Mayo Clinic AreaMed City Inn & Suites offers an inviting atmosphere just 2.1 km from Mayo Clinic, perfect for families. With a great traveler rating score of 8.0, this hotel features a fantastic waterslide and a children's pool to keep the little ones entertained. Guests can also enjoy complimentary breakfast, a kitchenette in the rooms, and a game room designed for family fun, ensuring a memorable stay.Kahler Grand HotelJust a 3-minute walk from Mayo Clinic, Kahler Grand Hotel is an ideal family-friendly choice with a review rating of 8.2 and a 3-star rating. Families will enjoy amenities like free cribs, connecting rooms, and a children's menu at the on-site restaurant. With its indoor pool and convenient location, travellers can easily balance relaxation and access to the clinic.

What are the best affordable hotels near Mayo Clinic?

Finding a budget-friendly hotel near Mayo Clinic can enhance your stay and provide peace of mind during your visit. Here are some top-rated options that offer great amenities without breaking the bank.Home2 Suites by Hilton Rochester Mayo Clinic AreaHome2 Suites by Hilton Rochester Mayo Clinic Area is a 3-star hotel located just 4.5 km from Mayo Clinic, with an impressive review rating of 9.6. This family-friendly hotel features complimentary breakfast daily, including a buffet on weekends, and offers a variety of amenities such as a fitness centre, free WiFi, and a kitchenette in each suite. Guests can also enjoy the convenience of free area shuttle service and on-site grocery shopping service.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott Rochester Mayo Clinic Area South is another excellent 3-star option, situated 4.5 km from Mayo Clinic with a stellar review rating of 9.6. Ideal for families, this hotel features a complimentary continental breakfast and an indoor pool perfect for relaxation. Guests will appreciate the fully equipped kitchens in the suites, free WiFi, and accessible fitness facilities to maintain their routine while traveling.Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysFairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys stands out with a prime location just 2.4 km from Mayo Clinic and a popular review rating of 9.6. This family-friendly hotel offers free breakfast options and access to an indoor pool, making it a great choice for leisure and relaxation. Additional amenities include free parking, WiFi, and a fitness centre, ensuring travellers have all they need for a comfortable stay.

Are there any hotels with pools close to Mayo Clinic?

If you're looking for hotels with pools near Mayo Clinic, Rochester offers some great options that cater to travellers seeking relaxation and comfort during their stay.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area is located only 8 minutes from Mayo Clinic and has an excellent review rating of 8.4. This hotel offers an indoor pool with features for children and accessibility options. Guests can also take advantage of free buffet breakfast, 24-hour fitness facilities, and easy access to nearby golf courses and historical sites.Best Western Rochester Hotel Mayo Clinic Area/St. Mary'sBest Western Rochester Hotel Mayo Clinic Area/St. Mary's is conveniently located just 3.5 km from Mayo Clinic, making it an ideal choice for travellers. With an impressive review rating of 8.2, this hotel features an indoor pool complete with a waterslide and children's area—perfect for families. Guests can also enjoy free breakfast, a hot tub, and easy access to local golf courses.Kahler Inn and Suites - Mayo Clinic AreaKahler Inn and Suites - Mayo Clinic Area is just a 3-minute walk from Mayo Clinic and boasts a great traveler rating score of 7.8. This family-friendly hotel features an indoor pool with accessibility options, making it suitable for everyone. Guests can enjoy amenities like a kitchenette in the rooms, free breakfast, and covered parking, ensuring a comfortable stay.

What are the best pet-friendly hotels near Mayo Clinic?

For travellers seeking pet-friendly accommodations near the Mayo Clinic, these top-rated hotels offer welcoming stays for both you and your furry friend.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott stands out with an impressive 9.6 travellers' rating and is located 4.5 km from the Mayo Clinic. This 3-star hotel allows both dogs and cats, making it a perfect choice for travellers with pets. Guests will appreciate the complimentary breakfast, an indoor pool, and a fitness centre. Additional features include a fully equipped kitchen in every suite and convenient parking options.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaCenterstone Plaza Hotel Soldiers Field is just an 8-minute walk from the Mayo Clinic and has a welcoming atmosphere for pets, earning a review rating of 8.4. This 3-star hotel features an indoor pool, free buffet breakfast, and a fitness centre. Guests can also enjoy nearby golf, a terrace, and family-friendly amenities such as cribs and kid-friendly meals.Med City Inn & Suites - Mayo Clinic AreaMed City Inn & Suites is a cozy and inviting option just 2.1 km from the Mayo Clinic, with a solid review rating of 8.0. This pet-friendly hotel welcomes dogs and offers essential amenities like free breakfast, an indoor pool, and a hot tub, ensuring a comfortable stay. Guests can also enjoy a fitness centre, kitchenette options, and complimentary toiletries.

Can I book a fully refundable hotel close to Mayo Clinic?

Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Mayo Clinic", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.

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Find hotels near Mayo Clinic, Rochester from CA $112

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Be picky

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Our top choices for Mayo Clinic hotels

1. Kahler Grand Hotel

2. Kahler Inn and Suites - Mayo Clinic Area

3. Hotel Indigo Rochester – Mayo Clinic Area by IHG

4. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

5. Hilton Rochester Mayo Clinic Area

6. Hyatt House Rochester/Mayo Clinic Area

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. TownePlace Suites by Marriott Rochester Mayo Clinic Area

9. Brentwood Inn & Suites

10. Hilton Garden Inn Rochester Downtown, MN

11. The Berkman

12. Marriott Rochester Mayo Clinic

13. Med City Inn & Suites - Mayo Clinic Area

14. Residence Inn by Marriott Rochester Mayo Clinic Area

15. Staybridge Suites Rochester - Mayo Clinic Area by IHG

16. Aspen Suites

17. Aspen Select

18. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

19. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Compare popular hotels close to Mayo Clinic

Top Mayo Clinic Hotel Reviews

Hilton Rochester Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Kahler Grand Hotel

Hilton Garden Inn Rochester Downtown, MN

AmericInn by Wyndham Rochester Near Mayo Clinic

The Berkman

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Aspen Select

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Frequently asked questions

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