Book The Best Hotels in San Carlos Island, FL for 2026 from CA $97 - Fully Refundable Options

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Our top choices for San Carlos Island hotels

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

1. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Fort Myers Beach

Kimberly

CA $160 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

2. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Fort Myers Beach

Melanie

CA $141 total

includes taxes & fees

Nov 16 - Nov 17

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

3. The Lighthouse Resort Inn & Suites

Fort Myers Beach

Shayne

CA $156 total

includes taxes & fees

Nov 15 - Nov 16

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

4. Residence Inn by Marriott Fort Myers Sanibel

Fort Myers

Lora

CA $174 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor seating area with a fire pit, outdoor furniture, and a covered patio.

5. TownePlace Suites by Marriott Fort Myers Gulf Coast

Fort Myers

Kevin

CA $150 total

includes taxes & fees

Nov 28 - Nov 29

A large, clear swimming pool with multiple lounge areas and palm trees.

6. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Lance

CA $355 total

includes taxes & fees

Nov 29 - Nov 30

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

7. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Siesta Isle

Maria

CA $164 total

includes taxes & fees

Nov 15 - Nov 16

A beach with a variety of seashells and pebbles.

8. Sanibel Island Beach Resort

Mid Island

Victoria

CA $354 total

includes taxes & fees

Nov 15 - Nov 16

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

9. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Fort Myers

Samantha

CA $139 total

includes taxes & fees

Nov 23 - Nov 24

A balcony with wicker furniture, a view of a beach, and a clear sky.

10. Lani Kai Beachfront Resort

Fort Myers Beach

yeny

CA $248 total

includes taxes & fees

Dec 3 - Dec 4

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

11. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

Sherri

CA $160 total

includes taxes & fees

Nov 17 - Nov 18

A wooden deck with outdoor seating, a thatched-roof structure, and string lights.

12. Latitude 26 Waterfront Resort & Marina

Fort Myers Beach

Mitchel

CA $137 total

includes taxes & fees

Nov 16 - Nov 17

A balcony with a table and chairs, large windows, and a view of the sea.

13. The Westin Cape Coral Resort At Marina Village

Pelican

Charles

CA $295 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

14. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

Bruce

CA $136 total

includes taxes & fees

Nov 29 - Nov 30

A hotel with a covered entrance, palm trees, and a well-maintained garden.

15. Homewood Suites by Hilton - Fort Myers

Villas

Anne

CA $173 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

16. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

CA $108 total

includes taxes & fees

Nov 15 - Nov 16

A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

17. Best Western Plus Beach Resort

Fort Myers Beach

Stacy

CA $343 total

includes taxes & fees

Nov 29 - Nov 30

18. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Villas

Rick

CA $138 total

includes taxes & fees

Nov 22 - Nov 23

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

19. Marriott Sanibel Harbour Resort & Spa

Punta Rassa

Yunior

CA $403 total

includes taxes & fees

Nov 29 - Nov 30

A Drury Inn & Suites hotel with a parking lot full of cars.

20. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

CA $188 total

includes taxes & fees

Dec 1 - Dec 2

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Stay near popular San Carlos Island attractions

Ostego Bay Marine Science Center

8.4/10 (15 reviews)

You can spend time studying the exhibits at Ostego Bay Marine Science Center in Fort Myers Beach. Stroll along the beautiful beaches in this family-friendly area, or check out its lively bars.

See properties

Top San Carlos Island Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

10/10 Excellent

We had a wonderful stay at Holiday Inn Express Cape Coral. The hotel was very clean, comfortable, and well maintained. A special thank you to Molly at the front desk. She was incredibly friendly, welcoming, and helpful from the moment we arrived. She made us feel truly valued as guests. We would also like to recognize the wonderful lady working in the breakfast area. She kept everything clean, fresh, and well organized, and she was always kind and attentive. The breakfast was excellent, and her...

Isaura