Name: 21C Museum Hotel St Louis
Price range: CA $172
Rating: 9

Your East Carondelet Vacation

Say farewell to planning worries and hello to a East Carondelet vacation package. With everything organized before you leave, you can focus on discovering the best of this city, starting with Soulard, which is great for distilleries and craft breweries, bars and pubs and markets. If sightseeing is on the to-do list during your trip to East Carondelet, swing by well-known attractions like Busch Stadium, Missouri Botanical Gardens and Arboretum and Anheuser-Busch Brewery. Your perfect East Carondelet vacation is just a few clicks away. Browse airfares, hotels and more on Expedia for a getaway that's tailored to suit your style.

Top East Carondelet Vacation Deals

Price found within the past 48 hours. Click for updated prices.

The Wildwood Hotel

CA $919

per person

May 12 - May 16

found 22 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

9.2/10 Wonderful! (1,626 reviews)

Great space for a couple

Reviewed on Mar 11, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

CA $1,237

per person

May 12 - May 16

found 22 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

8.8/10 Excellent! (1,060 reviews)

The property was beautiful and unique. The food was a disappointment. Unfortunately it was just too greasy for us.

Reviewed on Mar 6, 2026

Home2 Suites by Hilton St. Louis Downtown

Downtown West

CA $1,098

per person

May 3 - May 9

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

8/10 Very Good! (690 reviews)

We booked this hotel for the vicinity to the Dome and for the known chain name. There were several issues during our stay that i think were significant due to the fact the hotel was sold out for the weekend: Parking is only valet and there was only one person working valet, so, could take up to 45min to get the vehicle 3 elevators but only 1 was working We didnt have hot water the first morning we showered The handle on our bathroom drawer was broken, the piece put in the drawer, when we arrived There were dirty dishes from the previous guest in the dishwasher, which caused the room to smell bad

Reviewed on Mar 9, 2026

The West End

Central West End

CA $1,025

per person

May 3 - May 9

found 1 day ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

8.6/10 Excellent! (440 reviews)

Very welcoming staff, hotel was clean

Reviewed on Mar 2, 2026

Hilton Pennywell St. Louis at the Arch

Downtown St. Louis

CA $1,112

per person

May 12 - May 16

found 22 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

8.8/10 Excellent! (1,027 reviews)

Yea but truly my wife was the star of theshow

Reviewed on Feb 23, 2026

Ready to book your vacation to East Carondelet?

Choose your dates

East Carondelet Hotel Deals

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

CA $142

CA $166 total

Mar 22 - Mar 23

includes taxes & fees

8.8/10 Excellent! (3,103 reviews)

This is an older property, but very clean, comfortable, spacious and convenient to downtown Clayton. Parking was convenient and free on the weekend. Breakfast was better than average, with chef-made omelets and waffles.

Reviewed on Mar 11, 2026

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

CA $183

CA $214 total

Mar 16 - Mar 17

includes taxes & fees

9.4/10 Exceptional! (3,362 reviews)

Very nice staff and great atmosphere. Quietest hotel room i have ever stayed in

Reviewed on Mar 10, 2026

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

CA $172

CA $208 total

Apr 5 - Apr 6

includes taxes & fees

9/10 Wonderful! (1,648 reviews)

Such a cool hotel I love the museum on the second floor so interesting and all the penguins food is great restaurants great everything just what a great stay very unique but very quiet very cozy love everything about it. Can’t wait to stay at the other ones.

Reviewed on Mar 11, 2026

See all 1,736 properties in East Carondelet

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.