A serene lake with trees reflecting in the water, surrounded by a forest of tall, slender trees with autumn foliage.

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Top Cities in Orangeburg County

A calm lake with autumn-colored trees and a clear blue sky.
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Orangeburg

Orangeburg

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Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

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Our top choices for Orangeburg County hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,004 reviews)
"Property was clean and the breakfast was delicious would stay there again."
United States
Melissa
The price is CA $188
CA $208 total
includes taxes & fees
Sep 28 - Sep 29
Fairfield Inn & Suites by Marriott Santee
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

2. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (962 reviews)
"Great place to stay!"
United States
Connor
The price is CA $141
CA $157 total
includes taxes & fees
Oct 4 - Oct 5
Tru By Hilton Santee
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

3. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,496 reviews)
"Very quiet, dog friendly, clean, breakfast included."
United States
Yomerys
The price is CA $112
CA $124 total
includes taxes & fees
Sep 27 - Sep 28
Baymont by Wyndham Santee
A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

4. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very good, (1,003 reviews)
"My stay was comfortable and awesome I will be visiting again"
United States
TaNikka
The price is CA $136
CA $152 total
includes taxes & fees
Oct 4 - Oct 5
Spark by Hilton Orangeburg
A self-service kiosk with a beverage cooler, microwave, and various food items.

5. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
"Very much enjoyed our stay. Very friendly staff."
United States
Deborah
The price is CA $159
CA $177 total
includes taxes & fees
Oct 7 - Oct 8
Tru by Hilton Orangeburg
A water park with a pool, slides, and umbrellas.

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
"I stay here all the time when traveling with my dog. This place is super clean and the staff is excellent."
United States
Dennis
The price is CA $140
CA $155 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Santee by IHG
A hotel entrance with a sign reading "Best Western PLISS."

7. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,005 reviews)
"My best stay yet in Santee!! Love this place"
United States
shannon
The price is CA $166
CA $185 total
includes taxes & fees
Oct 4 - Oct 5
Best Western Plus Santee Inn
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

8. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,006 reviews)
"Was a good place to stay"
United States
santa
The price is CA $151
CA $167 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn & Suites Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

9. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,001 reviews)
"Great location, room and staff."
United States
Herbert
The price is CA $177
CA $197 total
includes taxes & fees
Oct 15 - Oct 16
Hampton Inn Santee-I-95
A tent with a view of a lake and boats, a wooden chair, and a potted plant.

10. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (101 reviews)
"Love it"
United States
Mark
The price is CA $104
CA $120 total
includes taxes & fees
Sep 24 - Sep 25
Bells Marina & Resort
A lobby with a reception desk, a sofa, a small round table, and an American flag.

11. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (857 reviews)
"Helpful staff, great breakfast buffet"
United States
Jenelyn
The price is CA $154
CA $171 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express & Suites Orangeburg by IHG
A breakfast bar with pastries, fruits, and a vase with flowers.

12. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very good, (1,003 reviews)
"We had a great stay. The staff were so friendly and helpful (a rare find these days). The hotel was very clean and smelled great. We will absolutely stay there again."
United States
Beth
The price is CA $97
CA $107 total
includes taxes & fees
Sep 23 - Sep 24
Travelodge by Wyndham Orangeburg
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

13. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (594 reviews)
"noisy AC unit overflowing trash cans broken vending machine"
United States
Mark
The price is CA $85
CA $102 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn & Suites Santee I-95
A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

14. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (816 reviews)
"Great Place to Stay!"
United States
Henrietta
The price is CA $153
CA $169 total
includes taxes & fees
Oct 1 - Oct 2
SpringHill Suites by Marriott Orangeburg
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

15. Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (705 reviews)
"I like everything."
United States
Ruben
The price is CA $84
CA $93 total
includes taxes & fees
Oct 18 - Oct 19
Quality Inn & Suites Orangeburg
A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

16. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (829 reviews)
"Amazing hotel. Always my go to whenever I am staying in Orangeburg. Highly recommended!"
United States
Percy
The price is CA $141
CA $157 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield Inn by Marriott Orangeburg
A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

17. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (849 reviews)
"Everything about the hotel was great"
United States
RODERICK V
The price is CA $183
CA $203 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites Orangeburg
A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.

18. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
2.0 star property
Orangeburg
5.8 out of 10, (744 reviews)
"Nice place to stay at an affordable price during our trip to Disney it was our halfway point"
United States
phyllis
The price is CA $82
CA $91 total
includes taxes & fees
Sep 29 - Sep 30
Red Roof Inn Orangeburg

19. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (593 reviews)
"The price rate was great"
United States
Stevenson
The price is CA $116
CA $129 total
includes taxes & fees
Sep 27 - Sep 28
Ramada by Wyndham Santee I-95
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

20. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (776 reviews)
"Great service"
United States
Kunjan
The price is CA $89
CA $99 total
includes taxes & fees
Sep 28 - Sep 29
Travelodge by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Orangeburg County, SC

Showing deals for:Oct 2 - Oct 4

Image gallery for Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Interior

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Bowman
9.8/10Exceptional (35 reviews)
10% off
Price is CA $107
CA $355 total
includes taxes & fees
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
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Top Orangeburg County Hotel Reviews

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg

8/10 Good
"Rooms were clean and well maintained."
Edward 1-night trip
Posted 1 day ago
Hampton Inn & Suites Orangeburg

Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from CA $91 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 22ºC and 32ºC. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at CA $91 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Expedia is your one-stop shop for planning the ultimate holiday experience in Orangeburg County. You'll find a wide variety of hotels to select from and handy search filters that make it a breeze to find what you're looking for. Worried about your plans changing? Many of our hotels have flexible cancellation policies, because we know flexibility matters. Get more out of your trip with Expedia Rewards. Join for free today to start collecting points and unlocking membership perks. You'll enjoy instant access to Member Prices, which means you can save 10% or more on select hotels!

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