Title: Book The Best Hotels in Orangeburg County, SC for 2026 from CA $84 - Fully Refundable Options - Expedia.ca [Orangeburg County Hotels](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations)[Vacation Rentals in Orangeburg County](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Vacation-Rental-Destinations)[Orangeburg County Car Rentals](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Car-Rental-Destinations) ![DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Go beyond your typical stay in Orangeburg County Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2026-03-05&d1=2026-03-05&endDate=2026-03-07&d2=2026-03-07&amenities=PETS) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2026-03-05&d1=2026-03-05&endDate=2026-03-07&d2=2026-03-07&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2026-03-05&d1=2026-03-05&endDate=2026-03-07&d2=2026-03-07&amenities=POOL) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2026-03-05&d1=2026-03-05&endDate=2026-03-07&d2=2026-03-07&lodging=CABIN) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2026-03-05&d1=2026-03-05&endDate=2026-03-07&d2=2026-03-07&lodging=APARTMENT) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2026-03-05&d1=2026-03-05&endDate=2026-03-07&d2=2026-03-07&lodging=COTTAGE) Condo [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2026-03-05&d1=2026-03-05&endDate=2026-03-07&d2=2026-03-07&lodging=CONDO) ## Check prices for these dates Tonight [Feb 19 - Feb 20](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-19&endDate=2026-02-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel) Tomorrow [Feb 20 - Feb 21](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-20&endDate=2026-02-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel) This weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel) Next weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel) ## Our top choices for Orangeburg County hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a0deabe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/f12ce994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a9d1fec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very good (727 reviews) "Overall a great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy CA $115 CA $128 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (728 reviews) "Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $148 CA $164 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/1ffbf2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/fcd98400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,001 reviews) "Liked the size of the room, the staff and the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia CA $176 CA $196 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/f2adc30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c5155ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) Orangeburg 9.2/10 Wonderful (1,006 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $155 CA $173 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,003 reviews) "Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcia CA $190 CA $210 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,429 reviews) "Room were very clean and staff was very helpful. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charolette CA $109 CA $121 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,001 reviews) "Courteous reception,clean rooms and great breakfast! Have been there many times in the last 15 years and I will return.!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Roger CA $153 CA $170 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,004 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale CA $144 CA $160 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2557x0y3-a96a0495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2557x3y3-7acc8337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2558x3y4-5a11a251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) Orangeburg 7.8/10 Good (1,002 reviews) "Clean rooms, good location, nice and polite staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenya CA $130 CA $145 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Orangeburg 8.8/10 Excellent (703 reviews) "3rd stay at this location would highly recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Athanassios CA $143 CA $159 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c19ebd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/37c1c14e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/ee5c02dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Orangeburg by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) Orangeburg 8.6/10 Excellent (806 reviews) "Room was clean and comfortable. The employees were helpful and efficient. Overall good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) margaret CA $144 CA $159 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5f0b6fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/6fa02d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (1,001 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $158 CA $175 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/44be5cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/e844503c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/ca4d16db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) Orangeburg 9.4/10 Exceptional (783 reviews) "We travel regularly and this was the best breakfast of any of the places we had stayed. Facility was clean and service was friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet CA $178 CA $198 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/97d6098f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/5e401dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/a14fcdea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/2616bf68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) Orangeburg 7.8/10 Good (398 reviews) "Very clean, comfortable beds, friendly staff. would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele CA $106 CA $118 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.2/10 Good (699 reviews) "Nice quiet room and a delicious breakfast at a reasonable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph B CA $82 CA $91 total includes taxes & fees Mar 5 - Mar 6 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/ee0f57db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Non Smoking, Lake View](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/b0419165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bells Marina & Resort [](https://www.expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) Eutawville 8.6/10 Excellent (87 reviews) "Super quaint, quiet, nice little get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen [](https://www.expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) ![Suite, 1 King Bed, Accessible, Smoking](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/81259c64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/6a21d794.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/d44bb419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/3f3e2740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) Orangeburg 6.2/10 (636 reviews) "Clean and staff very pleasant" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Larry CA $80 CA $89 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) ![Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/2dd4e6c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/cc6b1fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/c5e580c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/09406598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) Orangeburg 8.0/10 Very good (574 reviews) "Nice room and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $145 CA $161 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/50891687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (476 reviews) "Clean room but needs an exhaust fan in the bathroom " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leesa CA $74 CA $90 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/b15e751d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3e8501ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/581bc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/cfcbf535.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Orangeburg North [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) Orangeburg 6.0/10 (1,000 reviews) "The rooms were clean and staff was courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yojuana CA $76 CA $84 total includes taxes & fees Feb 25 - Feb 26 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-05&endDate=2026-03-06®ionId=553248635996998003&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOrangeburg-County.d553248635996998003.Destination-Travel-Guides)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOrangeburg-County.d553248635996998003.Destination-Travel-Guides) ## Top Orangeburg County Hotel Reviews ## Recent Reviews in Orangeburg County ![Comfort Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f_y.jpg) ### Comfort Inn & Suites Orangeburg 10/10 Excellent "Clean and spacious room, good staff with nice breakfast options as well for our 2 night stay there due to an emergency at the family home close by. Our family enjoyed the stay while there." [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Room was nice and clean. Great staff and very personable front Desk. I must say usually the breakfast buffet is just so so but the woman running the breakfast Beverly was just outstanding and she really made everything from the biscuits to the scrambled eggs standout. " [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "Super clean hotel. Loved the room. Shower pressure was amazing. Breakfast was good to. I will deff be back!" [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 10/10 Excellent "Clean room, quiet, good continental breakfast. Friendly staff." [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![SpringHill Suites by Marriott Orangeburg](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69_y.jpg) ### SpringHill Suites by Marriott Orangeburg 10/10 Excellent "This was a great stay for a somber family gathering." [](https://expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Fairfield Inn by Marriott Orangeburg](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27_y.jpg) ### Fairfield Inn by Marriott Orangeburg 10/10 Excellent "The room was large & clean. The bed was comfortable with modern bedding. The bathroom (just a shower) was clean & modern. All the staff we encountered were friendly and helpful. Very good value for money. Would stay again if in the area." [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 10/10 Excellent "Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed." [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Hampton Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914_y.jpg) ### Hampton Inn & Suites Orangeburg 10/10 Excellent "We travel regularly and this was the best breakfast of any of the places we had stayed. Facility was clean and service was friendly." [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "Clean, spacious room. Comfortable bed. Quiet " [](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ## More cheap stays in Orangeburg County ![Super 8 by Wyndham, Orangeburg](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham, Orangeburg 3608 Saint Matthews Rd Orangeburg SC CA $79 CA $87 total Mar 15 - Mar 16 includes taxes & fees 6.8/10 (916 reviews) [](https://expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Motel 6 West Columbia, SC - Airport](https://images.trvl-media.com/lodging/2000000/1130000/1123200/1123132/d424a6cf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 West Columbia, SC - Airport 650 Cherokee Lane West Columbia SC CA $84 CA $91 total Feb 23 - Feb 24 includes taxes & fees 7.6/10 Good! (497 reviews) [](https://expedia.ca/West-Columbia-Hotels-Motel-6-West-Columbia.h1123132.Hotel-Information) ![Motel 6 Summerville, SC – Charleston](https://images.trvl-media.com/lodging/1000000/10000/8600/8538/b64d4a44_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Summerville, SC – Charleston 110 Holiday Dr Summerville SC CA $99 CA $111 total Mar 1 - Mar 2 includes taxes & fees 6.2/10 (623 reviews) [](https://expedia.ca/Charleston-Hotels-Econo-Lodge-Summerville.h8538.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street Santee SC CA $109 CA $121 total Mar 8 - Mar 9 includes taxes & fees 8/10 Very Good! (1,429 reviews) [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![avid hotel Summerville by IHG](https://images.trvl-media.com/lodging/60000000/59550000/59543900/59543873/9309c578_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### avid hotel Summerville by IHG 301 Holiday Drive Summerville SC CA $141 CA $159 total Mar 15 - Mar 16 includes taxes & fees 9/10 Wonderful! (788 reviews) [](https://expedia.ca/Charleston-Hotels-Avid-Hotels-Summerville.h59543873.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St. Santee SC CA $148 CA $164 total Feb 25 - Feb 26 includes taxes & fees 9.2/10 Wonderful! (728 reviews) [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app