Title: Top Hotels in Orangeburg County | Expedia.ca [Vacation Rentals in Orangeburg County](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Vacation-Rental-Destinations)[Orangeburg County Car Rentals](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Car-Rental-Destinations)[Orangeburg County Vacations](https://expedia.ca/Orangeburg-County.d553248635996998003.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/271db9a9db85f6f3488271b71d2f238f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Orangeburg County Hotels ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Orangeburg County Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&amenities=PETS) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&travelerType=family_friendly) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=CABIN) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=COTTAGE) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=APARTMENT) Pool [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&amenities=POOL) ## Top Cities in Orangeburg County ![](https://mediaim.expedia.com/destination/2/d91715fa11e9d5570856838fd5bd4287.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Orangeburg [](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-10-18&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels in Orangeburg County ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1371) "Good overall stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Junming CA $105 CA $117 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/321b05a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2557x0y3-a96a0495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2557x3y3-7acc8337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg Orangeburg 7.8/10 Good (1010) "Clean, quiet, nice place for an overnight stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $122 CA $136 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/a4197341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg Orangeburg 9.2/10 Wonderful (1008) "Great little hotel. Perfect for a short stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $148 CA $165 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/8f64bf7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/828f10f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee Santee 9.2/10 Wonderful (566) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon CA $137 CA $153 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/67341601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee Santee 9.8/10 Exceptional (1006) "Great stay for a quick weekend getaway!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle CA $175 CA $195 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/10951979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/c97df40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee 6.0/10 (443) "Great place. Excellent people. Great service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse CA $76 CA $92 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/e27bc6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/442e4efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG Santee 8.2/10 Very good (955) "Great hotel w" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $165 CA $184 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/ddfa8a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/6e319d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee Santee 8.0/10 Very good (1003) "The room and Hotel was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $149 CA $165 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Standard Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f6e62ff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/09bb2a32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f848d3f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/500cab17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Orangeburg Orangeburg 5.6/10 (700) "Simple hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) FNU CA $67 CA $74 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Orangeburg-Hotels-Days-Inn-By-Wyndham-Orangeburg.h100411.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/c7fdb599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/6dc9f9a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg Orangeburg 8.4/10 Very good (658) "Enjoyed my stay for homecoming go Bulldogs ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $118 CA $131 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/cc21c252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg Orangeburg 8.8/10 Excellent (652) "Everything is so nice! Spacious, comfortable, clean rooms. Attractive facility. Nice setting. Convenient to restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $153 CA $170 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/5f1ffd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Smoking | Bathroom sink](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/13cfcb42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg Orangeburg 8.2/10 Very good (1005) "Enjoyed our stay " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Marie CA $100 CA $111 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/e757bdfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5897ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 Santee 9.6/10 Exceptional (1004) "Rooms were nice size and very clean. Staff was so nice and helped us find some local spots to eat. Highly recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $168 CA $187 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/acf6709b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/a8856fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c87bee2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham, Orangeburg Orangeburg 6.8/10 (867) "I was only looking for a 1 night stay then back on the road. It was the perfect choice. Also a short drive to Congaree National Park" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $81 CA $90 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/2e89db8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/a07c5e78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/1732be44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Orangeburg by IHG Orangeburg 8.6/10 Excellent (785) "Easley to find, clean, great breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) albert CA $153 CA $170 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/cc6b1fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/1c1fc707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/208c4454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg 8.0/10 Very good (517) "EVERYTHING WAS CLEAN AND NICE" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $137 CA $152 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/ca4d16db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/w3840h2555x0y0-c192cb06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/4f595493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/f8dc077a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Orangeburg Orangeburg 9.4/10 Exceptional (739) "Very convenient location. I was visiting my niece who goes to college in Orangeburg and the hotel was very convenient for all of our activities in town and Columbia. Comfortable beds, quiet, and clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $161 CA $178 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/4aad61ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn Santee 8.8/10 Excellent (1007) "We really enjoyed our stay and will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $167 CA $185 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3e8501ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/b15e751d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/581bc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Orangeburg North Orangeburg 6.0/10 (1015) "Very clean and quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Niquisha CA $95 CA $106 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee Santee 7.0/10 Good (663) "Good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $86 CA $95 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=553248635996998003&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ## Top Orangeburg County Hotel Reviews ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Orangeburg County - [Orangeburg Hotels](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) - [Santee Hotels](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels) - [Eutawville Hotels](https://expedia.ca/Eutawville-Hotels.d3000455924.Travel-Guide-Hotels) - [Holly Hill Hotels](https://expedia.ca/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Vance Hotels](https://expedia.ca/Vance-Hotels.d3000456153.Travel-Guide-Hotels) - [Bowman Hotels](https://expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Neeses Hotels](https://expedia.ca/Neeses-Hotels.d3000456036.Travel-Guide-Hotels) - [Rowesville Hotels](https://expedia.ca/Rowesville-Hotels.d3000353220.Travel-Guide-Hotels) - [Cope Hotels](https://expedia.ca/Cope-Hotels.d3000455896.Travel-Guide-Hotels) - [Norway Hotels](https://expedia.ca/Norway-Hotels.d553248634998816179.Travel-Guide-Hotels) - [Whetsell Hotels](https://expedia.ca/Whetsell-Hotels.d553248635974902828.Travel-Guide-Hotels) - [Cordova Hotels](https://expedia.ca/Cordova-Hotels.d553248634998610573.Travel-Guide-Hotels) - [North Hotels](https://expedia.ca/North-Hotels.d553248634999378506.Travel-Guide-Hotels) - [Woodford Hotels](https://expedia.ca/Woodford-Hotels.d553248634998789873.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Santee State Park](https://expedia.ca/Santee-State-Park-Hotels.0-l6140632-0.Travel-Guide-Filter-Hotels) - [Hotels near South Carolina State University](https://expedia.ca/South-Carolina-State-University-Hotels.0-l6193863-0.Travel-Guide-Filter-Hotels) - [Hotels near Santee Cooper Country Club](https://expedia.ca/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) - [Hotels near Santee National Golf Club](https://expedia.ca/Santee-National-Golf-Club-Hotels.0-l553248621532654897-0.Travel-Guide-Filter-Hotels) - [Hotels near Edisto Memorial Gardens](https://expedia.ca/Edisto-Memorial-Gardens-Hotels.0-l553248621532654892-0.Travel-Guide-Filter-Hotels) - [Hotels near I.P. Stanback Museum & Planetarium](https://expedia.ca/IP-Stanback-Museum-Planetarium-Hotels.0-l553248621561867626-0.Travel-Guide-Filter-Hotels) - [Hotels near Williams Brice Stadium](https://expedia.ca/Williams-Brice-Stadium-Hotels.0-l6193698-0.Travel-Guide-Filter-Hotels) - [Hotels near Congaree National Park](https://expedia.ca/Congaree-National-Park-Hotels.0-l6129970-0.Travel-Guide-Filter-Hotels) ### Hotels near Orangeburg County Airports - [Columbia Metropolitan Airport Hotels](https://expedia.ca/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels) - [Charleston Intl. Airport Hotels](https://expedia.ca/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels) ### More ways to book - [Book Hotels in Orangeburg County on Expedia.com](https://www.expedia.com/Destinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Hotels in Charleston Historic District](https://expedia.ca/Charleston-Historic-District-Charleston-Hotels.0-n6057948-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Boutique-Hotel.0-0-d178304-tBoutiqueHotel.Hotel-Filter-Destinations) - [Golf Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Golf-Hotel.0-0-d178304-tGolfHotel.Hotel-Filter-Destinations) - [Oceanfront Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Oceanfront-Hotels.0-0-d178304-tOceanfrontHotels.Hotel-Filter-Destinations) - [Hotels in Orange County](https://expedia.ca/Destinations-In-Orange-County.d603224.Hotel-Destinations) - [All Inclusive Resorts and Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-All-Inclusive-Hotel.0-0-d178304-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Luxury Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Luxury-Hotel.0-0-d178304-tLuxuryHotel.Hotel-Filter-Destinations) - [Mountain Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Mountain-Hotels.0-0-d178304-tMountainHotels.Hotel-Filter-Destinations) - [Hotels in Downtown Charleston](https://expedia.ca/Downtown-Charleston-Charleston-Hotels.0-n553248633938969537-0.Travel-Guide-Filter-Hotels) - [Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Hotel-Destinations) - [Family Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Family-Hotel.0-0-d178304-tFamilyHotel.Hotel-Filter-Destinations) - [Cheap Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Cheap-Hotels.0-0-d178304-tCheapHotels.Hotel-Filter-Destinations) - [Beach Hotel in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Beach-Hotel.0-0-d178304-tBeachHotel.Hotel-Filter-Destinations) Flights - [Cheap Flights to Orange County](https://expedia.ca/Destinations-In-Orange-County.d603224.Flight-Destinations) - [Cheap Flights to San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Flight-Destinations) Cars - [Car rentals in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Car-Rental-Destinations) - [Car rental Myrtle Beach Airport (MYR)](https://expedia.ca/Car-Rentals-In-Myrtle-Beach-Intl.d5396813.Car-Rental-Guide) Cruises - [Cruises from San Diego County](https://expedia.ca/Cruises-from-San-Diego-County.d178304.Cruise-Departure-Port) Activities - [Things to do in Baldwin County](https://expedia.ca/Things-To-Do-In-Baldwin-County.d553248635976432245.Travel-Guide-Activities) - [Things to do in San Diego County](https://expedia.ca/Things-To-Do-In-San-Diego-County.d178304.Travel-Guide-Activities) - [Things to do in Orange County](https://expedia.ca/Things-To-Do-In-Orange-County.d603224.Travel-Guide-Activities) - [Things to do in Levy County](https://expedia.ca/Things-To-Do-In-Levy-County.d553248635976432502.Travel-Guide-Activities) Packages - [San Diego County Packages](https://expedia.ca/San-Diego-County.d178304.Destination-Travel-Guides) - [Magnolia Plantation and Gardens](https://expedia.ca/Magnolia-Plantation-And-Gardens-Charleston.d6082613.Vacation-Attraction) - [Myrtle Beach State Park](https://expedia.ca/Myrtle-Beach-State-Park-Myrtle-Beach.d6079991.Vacation-Attraction) - [Ripley's Aquarium](https://expedia.ca/Ripleys-Aquarium-Myrtle-Beach.d6079963.Vacation-Attraction) - [Broadway at the Beach](https://expedia.ca/Broadway-At-The-Beach-Myrtle-Beach.d6079959.Vacation-Attraction) - [Family Kingdom Amusement Park](https://expedia.ca/Family-Kingdom-Amusement-Park-Myrtle-Beach.d6079999.Vacation-Attraction) General - [Visit Cherry Grove Beach](https://expedia.ca/North-Myrtle-Beach-Cherry-Grove-Beach.dx553248621561867974) - [Visit Orange County](https://expedia.ca/Orange-County.dx603224) ## Frequently asked questions ### How much do hotels in Orangeburg County cost? > Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more. ### When is the best time to go to Orangeburg County? > That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 22ºC and 32ºC. Orangeburg County has a humid subtropical climate, so keep that in mind when packing. ### How can I find cheap hotels in Orangeburg County? > The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our [cheap hotels in Orangeburg County](https://www.expedia.ca/Destinations-In-Orangeburg-County-Cheap-Hotels.0-0-d553248635996998003-tCheapHotels.Hotel-Filter-Destinations) page. ### What are the best hotels in Orangeburg County for families? > Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, [Fairfield Inn & Suites by Marriott Santee](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at [Hampton Inn Santee-I-95](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information). You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters. ### Why should I book my Orangeburg County hotel with Expedia? > Expedia is your one-stop shop for planning the ultimate holiday experience in Orangeburg County. You'll find a wide variety of hotels to select from and handy search filters that make it a breeze to find what you're looking for. Worried about your plans changing? Many of our hotels have flexible cancellation policies, because we know flexibility matters. Get more out of your trip with Expedia Rewards. Join for free today to start collecting points and unlocking membership perks. You'll enjoy instant access to Member Prices, which means you can save 10% or more on select hotels! ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)