Title: Top Hotels in Orangeburg County | Expedia.ca [Vacation Rentals in Orangeburg County](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Vacation-Rental-Destinations)[Orangeburg County Car Rentals](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Car-Rental-Destinations)[Orangeburg County Vacations](https://expedia.ca/Orangeburg-County.d553248635996998003.Destination-Travel-Guides) ![DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Orangeburg County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Orangeburg County Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&travelerType=family_friendly) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&lodging=CABIN) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&amenities=PETS) Pool [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&amenities=POOL) Condo [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&lodging=CONDO) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&lodging=COTTAGE) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Orangeburg+County%2C+South+Carolina%2C+United+States+of+America®ionId=553248635996998003&latLong=33.49182%2C-80.855648&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&amenities=WATER_PARK) ## Top Cities in Orangeburg County ![](https://mediaim.expedia.com/destination/2/d91715fa11e9d5570856838fd5bd4287.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Orangeburg [](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Dec 4 - Dec 5](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-12-04&endDate=2025-12-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 5 - Dec 6](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-12-05&endDate=2025-12-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels in Orangeburg County ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/756b4cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1405) "The best stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terez CA $112 CA $124 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/8f64bf7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee Santee 9.2/10 Wonderful (624) "Nice place to stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Tanya CA $133 CA $147 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2557x0y3-a96a0495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2557x3y3-7acc8337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/321b05a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg Orangeburg 7.8/10 Good (1000) "Clean, quiet, nice place for an overnight stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $122 CA $135 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/a4197341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg Orangeburg 9.2/10 Wonderful (1001) "Staff are great, room is clean and amenities very amusing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Salah CA $144 CA $160 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/67341601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee Santee 9.8/10 Exceptional (1001) "Very welcoming, hotel has a clean and friendly presentation." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) VALERIE AND JOHN CA $169 CA $187 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/aa173c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/f8fbcf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/c7fdb599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg Orangeburg 8.4/10 Very good (684) "Enjoyed my stay for homecoming go Bulldogs ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $117 CA $130 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/6e319d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee Santee 8.0/10 Very good (1000) "Close to the highway with a safe location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin CA $138 CA $153 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Smoking | Bathroom sink](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/13cfcb42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/5f1ffd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Smoking](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/77c6db86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg Orangeburg 8.2/10 Very good (1000) "Enjoyed our stay " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Marie CA $94 CA $104 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5897ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/e757bdfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/65520f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 Santee 9.6/10 Exceptional (1001) "Breakfast was really good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vinicius CA $156 CA $173 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/208c4454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/cc6b1fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/5fe5c871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg Orangeburg 8.0/10 Very good (543) "Would recommend this hotel for out of town guest with no hesitation. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yvette CA $132 CA $147 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/442e4efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG Santee 8.2/10 Very good (970) "Was able to walk to convenience store and other dinning alternatives. Safe secure building" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan CA $155 CA $172 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c87bee2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/a8856fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/acf6709b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham, Orangeburg Orangeburg 6.8/10 (891) "Lovely front desk staff, very clean everywhere and nice breakfast. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Danica CA $80 CA $89 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/10951979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/ccd798ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/c97df40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee 6.0/10 (452) "Great place. Excellent people. Great service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesse CA $76 CA $92 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/133748ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/f8dc077a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/4f595493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Orangeburg Orangeburg 9.4/10 Exceptional (754) "lady at checkin very welcoming! also something like a couple bottles of water can be nice surprise to travelers " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cheryl CA $155 CA $172 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Standard Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f6e62ff1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/f848d3f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/7a5d2e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/100500/100411/500cab17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Orangeburg Orangeburg 5.6/10 (714) "Clean room quiet stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sammy CA $58 CA $65 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Orangeburg-Hotels-Days-Inn-By-Wyndham-Orangeburg.h100411.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e0b4742d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg Orangeburg 8.8/10 Excellent (671) "The room was perfect and the staff was friendly and welcoming " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Milton CA $146 CA $162 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-refrigerator](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/de5b8443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3e8501ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/581bc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Orangeburg North Orangeburg 6.0/10 (1001) "Very clean and quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Niquisha CA $77 CA $86 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/2e89db8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/acfce64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/1732be44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Orangeburg by IHG Orangeburg 8.6/10 Excellent (793) "The room was spotless and the staff was courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terrance CA $133 CA $147 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/4aad61ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn Santee 8.8/10 Excellent (1001) "Nice rooms and very good breakfast items." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $165 CA $183 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/97d6098f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/159dba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/5e401dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/02857169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Orangeburg Orangeburg 7.6/10 Good (379) "Courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $103 CA $114 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-18&endDate=2025-12-19®ionId=553248635996998003&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Orangeburg County, SC Showing deals for:**Dec 12 - Dec 14** ### Image gallery for Waterfront Condo on Lake Marion ![Pool](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/fb378afa.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Waterfront Condo on Lake Marion Santee **10/10**Exceptional (6 reviews) 10% off CA $483 CA $1,516 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=102018216&adults=2) ### Image gallery for The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. ![Exterior](https://images.trvl-media.com/lodging/55000000/54180000/54171600/54171514/cebbaa06.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. Eutawville **10/10**Exceptional (39 reviews) 10% off CA $213 CA $683 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=54171514&adults=2) ### Image gallery for Wyndham Vacation Resorts Lake Marion ![Exterior](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Wyndham Vacation Resorts Lake Marion Santee **9.2/10**Wonderful (20 reviews) 20% off CA $261 CA $580 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=43992569&adults=2) ### Image gallery for Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301 ![Outdoor dining](https://images.trvl-media.com/lodging/77000000/76600000/76591800/76591706/994fdf59.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301 Bowman **10/10**Exceptional (30 reviews) 10% off CA $107 CA $355 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=76591706&adults=2) ### Image gallery for Bells Marina & Resort ![Cabin, 1 Bedroom, Non Smoking, Lake View | Private kitchen](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/a4a585ea.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Bells Marina & Resort Eutawville **8.6/10**Excellent (78 reviews) 10% off CA $120 CA $266 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=91244689&adults=2) ### Image gallery for Tru by Hilton Orangeburg ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Tru by Hilton Orangeburg Orangeburg **9.2/10**Wonderful (1,001 reviews) 20% off CA $166 CA $369 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=34323336&adults=2) ### Image gallery for Pet friendly country cottage with large fenced-in yard & horses on property ![Property grounds](https://images.trvl-media.com/lodging/96000000/96000000/95993200/95993146/6d916484.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Pet friendly country cottage with large fenced-in yard & horses on property Holly Hill **10/10**Exceptional (122 reviews) 10% off CA $188 CA $567 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=95993146&adults=2) ### Image gallery for Hampton Inn & Suites Orangeburg ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hampton Inn & Suites Orangeburg Orangeburg **9.4/10**Exceptional (754 reviews) 20% off CA $200 CA $444 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=9854604&adults=2) ### Image gallery for Beautiful brick home w/ large porch and 3 bedrooms ![Outdoor dining](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/d8b442d6.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Beautiful brick home w/ large porch and 3 bedrooms Bowman **9.0/10**Wonderful (4 reviews) 10% off CA $207 CA $650 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=112528151&adults=2) ### Image gallery for Comfort Inn & Suites Orangeburg ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Comfort Inn & Suites Orangeburg Orangeburg **8.0/10**Very good (543 reviews) 20% off CA $133 CA $295 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=1990272&adults=2) ### Image gallery for Comfort Inn & Suites Santee ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Comfort Inn & Suites Santee Santee **8.0/10**Very good (1,000 reviews) 20% off CA $155 CA $343 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=518401&adults=2) ### Image gallery for Travelodge by Wyndham Orangeburg ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Travelodge by Wyndham Orangeburg Orangeburg **8.2/10**Very good (1,000 reviews) 20% off CA $99 CA $221 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-14&selected=17380261&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ## Top Orangeburg County Hotel Reviews ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 10/10 Excellent "Was able to walk to convenience store and other dinning alternatives. Safe secure building" [](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Nice" [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Bells Marina & Resort](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/a4a585ea_y.jpg) ### Bells Marina & Resort 10/10 Excellent "The staff was so friendly!!! Everything was amazing and they were so accommodating. Blew my mind at how willing they were to work with us despite us not realizing they closed check-in at 10, and we weren’t able to show up until 10:50 but they still stayed and checked us in. And they were so cheerful about it ❤️ Thank you guys so much you really saved us and made our short stay so peaceful. Also those were actually the most comfortable hotel beds I’ve ever slept in and I’ve stayed at some NICE hotels. Such a nice experience!" [](https://expedia.ca/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg) ### Comfort Inn & Suites Santee 10/10 Excellent "We like this location and have stayed here several times. We travel with our service dogs and this location has a nice outdoor area that is well lit at night for potty breaks. \*\*\*PLEASE NOTE…this hotel is NOT pet friendly. We will often seek out pet friendly facilities as a first option when we travel and this location comes up in the search. However upon arrival there’s a sign on the door that reads service animals only. I only mention it as a heads up. Our first stay we had prepaid for our room and if our dogs were not service animals we would have been in a bad situation as it was late when we arrived and would have had no place to go. Otherwise this is a great location and place to stay for us on our travels up and down I-95!" [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Comfort Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f_y.jpg) ### Comfort Inn & Suites Orangeburg 10/10 Excellent "Would recommend this hotel for out of town guest with no hesitation. " [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "Room was clean and staff was super nice. They even hosted a rubber ducky scavenger hunt to keep the kids entertained and my daughter won a prize. The lobby area is very inviting and you can just hang out in the evening. Breakfast options are good for a buffet breakfast. Overall great stay and I would stay there again. " [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 10/10 Excellent "Great staff" [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "The room was spotless and the bed was very comfortable. We went out for the day, we were surprised that our bed was made and had clean towels. " [](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Hampton Inn & Suites Orangeburg](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914_y.jpg) ### Hampton Inn & Suites Orangeburg 10/10 Excellent "Friendly staff and clean hotel. " [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Orangeburg County - [Orangeburg Hotels ](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) - [Santee Hotels ](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels) - [Eutawville Hotels ](https://expedia.ca/Eutawville-Hotels.d3000455924.Travel-Guide-Hotels) - [Holly Hill Hotels ](https://expedia.ca/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Vance Hotels ](https://expedia.ca/Vance-Hotels.d3000456153.Travel-Guide-Hotels) - [Bowman Hotels ](https://expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Whetsell Hotels ](https://expedia.ca/Whetsell-Hotels.d553248635974902828.Travel-Guide-Hotels) - [North Hotels ](https://expedia.ca/North-Hotels.d553248634999378506.Travel-Guide-Hotels) - [Rowesville Hotels ](https://expedia.ca/Rowesville-Hotels.d3000353220.Travel-Guide-Hotels) - [Norway Hotels ](https://expedia.ca/Norway-Hotels.d553248634998816179.Travel-Guide-Hotels) - [Neeses Hotels ](https://expedia.ca/Neeses-Hotels.d3000456036.Travel-Guide-Hotels) - [Cordova Hotels ](https://expedia.ca/Cordova-Hotels.d553248634998610573.Travel-Guide-Hotels) - [Cope Hotels ](https://expedia.ca/Cope-Hotels.d3000455896.Travel-Guide-Hotels) - [Woodford Hotels ](https://expedia.ca/Woodford-Hotels.d553248634998789873.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Santee State Park ](https://expedia.ca/Santee-State-Park-Hotels.0-l6140632-0.Travel-Guide-Filter-Hotels) - [Hotels near South Carolina State University ](https://expedia.ca/South-Carolina-State-University-Hotels.0-l6193863-0.Travel-Guide-Filter-Hotels) - [Hotels near Santee Cooper Country Club ](https://expedia.ca/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) - [Hotels near Santee National Golf Club ](https://expedia.ca/Santee-National-Golf-Club-Hotels.0-l553248621532654897-0.Travel-Guide-Filter-Hotels) - [Hotels near Edisto Memorial Gardens ](https://expedia.ca/Edisto-Memorial-Gardens-Hotels.0-l553248621532654892-0.Travel-Guide-Filter-Hotels) - [Hotels near I.P. Stanback Museum & Planetarium ](https://expedia.ca/IP-Stanback-Museum-Planetarium-Hotels.0-l553248621561867626-0.Travel-Guide-Filter-Hotels) - [Hotels near Williams Brice Stadium ](https://expedia.ca/Williams-Brice-Stadium-Hotels.0-l6193698-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Orangeburg County - [Vacation Homes in Orangeburg County ](https://expedia.ca/Orangeburg-County-Private-Vacation-Homes.d553248635996998003-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cottages in Orangeburg County ](https://expedia.ca/Orangeburg-County-Cottages.d553248635996998003-aaCottages.Travel-Guide-Accommodation) - [Apartments in Orangeburg County ](https://expedia.ca/Orangeburg-County-Apartments.d553248635996998003-aaApartments.Travel-Guide-Accommodation) - [Motels in Orangeburg County ](https://expedia.ca/Orangeburg-County-Motels.d553248635996998003-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in Orangeburg County ](https://expedia.ca/Orangeburg-County-Cabins.d553248635996998003-aaCabins.Travel-Guide-Accommodation) - [Condo Rentals in Orangeburg County ](https://expedia.ca/Orangeburg-County-Condos.d553248635996998003-aaCondos.Travel-Guide-Accommodation) - [Farmstay in Orangeburg County ](https://expedia.ca/Orangeburg-County-Agritourism.d553248635996998003-aaAgritourism.Travel-Guide-Accommodation) - [Resorts in Orangeburg County ](https://expedia.ca/Orangeburg-County-Resort-Hotels.d553248635996998003-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in Orangeburg County ](https://expedia.ca/Orangeburg-County-Apart-Hotels.d553248635996998003-aaApartHotels.Travel-Guide-Accommodation) - [RV Parks in Orangeburg County ](https://expedia.ca/Orangeburg-County-RV-Parks.d553248635996998003-aaRVParks.Travel-Guide-Accommodation) - [Lodges in Orangeburg County ](https://expedia.ca/Orangeburg-County-Lodges.d553248635996998003-aaLodges.Travel-Guide-Accommodation) - [Guest Houses in Orangeburg County ](https://expedia.ca/Orangeburg-County-Guest-Houses.d553248635996998003-aaGuestHouses.Travel-Guide-Accommodation) - [B&B in Orangeburg County ](https://expedia.ca/Orangeburg-County-Bed-And-Breakfast.d553248635996998003-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Country Houses in Orangeburg County ](https://expedia.ca/Orangeburg-County-Country-House.d553248635996998003-aaCountryHouse.Travel-Guide-Accommodation) ### Hotels near Orangeburg County Airports - [Columbia Metropolitan Airport Hotels ](https://expedia.ca/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels) - [Charleston Intl. Airport Hotels ](https://expedia.ca/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Tru By Hilton Santee ](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) - [Baymont by Wyndham Santee ](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) - [Tru by Hilton Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) - [Spark by Hilton Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) - [Fairfield Inn & Suites by Marriott Santee ](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) - [Days Inn by Wyndham Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Days-Inn-By-Wyndham-Orangeburg.h100411.Hotel-Information) - [Hampton Inn Santee-I-95 ](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) - [Holiday Inn Santee by IHG ](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) - [Comfort Inn & Suites Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) - [Comfort Inn & Suites Santee ](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) [See a list of all hotels in Orangeburg County](https://expedia.ca/All-Orangeburg-County-Hotels.d553248635996998003.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Orangeburg County on Expedia.com ](https://www.expedia.com/Destinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Hotels in Charleston Historic District](https://expedia.ca/Charleston-Historic-District-Charleston-Hotels.0-n6057948-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Boutique-Hotel.0-0-d178304-tBoutiqueHotel.Hotel-Filter-Destinations) - [Golf Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Golf-Hotel.0-0-d178304-tGolfHotel.Hotel-Filter-Destinations) - [Oceanfront Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Oceanfront-Hotels.0-0-d178304-tOceanfrontHotels.Hotel-Filter-Destinations) - [Hotels in Orange County](https://expedia.ca/Destinations-In-Orange-County.d603224.Hotel-Destinations) - [All Inclusive Resorts and Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-All-Inclusive-Hotel.0-0-d178304-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Luxury Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Luxury-Hotel.0-0-d178304-tLuxuryHotel.Hotel-Filter-Destinations) - [Mountain Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Mountain-Hotels.0-0-d178304-tMountainHotels.Hotel-Filter-Destinations) - [Hotels in Downtown Charleston](https://expedia.ca/Downtown-Charleston-Charleston-Hotels.0-n553248633938969537-0.Travel-Guide-Filter-Hotels) - [Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Hotel-Destinations) - [Family Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Family-Hotel.0-0-d178304-tFamilyHotel.Hotel-Filter-Destinations) - [Cheap Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Cheap-Hotels.0-0-d178304-tCheapHotels.Hotel-Filter-Destinations) - [Beach Hotel in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Beach-Hotel.0-0-d178304-tBeachHotel.Hotel-Filter-Destinations) Flights - [Cheap Flights to Orange County](https://expedia.ca/Destinations-In-Orange-County.d603224.Flight-Destinations) - [Cheap Flights to San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Flight-Destinations) Cars - [Car rentals in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Car-Rental-Destinations) - [Car rental Myrtle Beach Airport (MYR)](https://expedia.ca/Car-Rentals-In-Myrtle-Beach-Intl.d5396813.Car-Rental-Guide) Cruises - [Cruises from San Diego County](https://expedia.ca/Cruises-from-San-Diego-County.d178304.Cruise-Departure-Port) Activities - [Things to do in Baldwin County](https://expedia.ca/Things-To-Do-In-Baldwin-County.d553248635976432245.Travel-Guide-Activities) - [Things to do in San Diego County](https://expedia.ca/Things-To-Do-In-San-Diego-County.d178304.Travel-Guide-Activities) - [Things to do in Orange County](https://expedia.ca/Things-To-Do-In-Orange-County.d603224.Travel-Guide-Activities) - [Things to do in Levy County](https://expedia.ca/Things-To-Do-In-Levy-County.d553248635976432502.Travel-Guide-Activities) Packages - [San Diego County Packages](https://expedia.ca/San-Diego-County.d178304.Destination-Travel-Guides) - [Magnolia Plantation and Gardens](https://expedia.ca/Magnolia-Plantation-And-Gardens-Charleston.d6082613.Vacation-Attraction) - [Myrtle Beach State Park](https://expedia.ca/Myrtle-Beach-State-Park-Myrtle-Beach.d6079991.Vacation-Attraction) - [Ripley's Aquarium](https://expedia.ca/Ripleys-Aquarium-Myrtle-Beach.d6079963.Vacation-Attraction) - [Broadway at the Beach](https://expedia.ca/Broadway-At-The-Beach-Myrtle-Beach.d6079959.Vacation-Attraction) - [Family Kingdom Amusement Park](https://expedia.ca/Family-Kingdom-Amusement-Park-Myrtle-Beach.d6079999.Vacation-Attraction) General - [Visit Cherry Grove Beach](https://expedia.ca/North-Myrtle-Beach-Cherry-Grove-Beach.dx553248621561867974) - [Visit Orange County](https://expedia.ca/Orange-County.dx603224) ## Frequently asked questions ### How much do hotels in Orangeburg County cost? ### When is the best time to go to Orangeburg County? ### How can I find cheap hotels in Orangeburg County? ### What are the best hotels in Orangeburg County for families? ### Why should I book my Orangeburg County hotel with Expedia? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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