Title: Top Hotels in Orangeburg County | Expedia.ca [Vacation Rentals in Orangeburg County](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Vacation-Rental-Destinations)[Orangeburg County Car Rentals](https://expedia.ca/Destinations-In-Orangeburg-County.d553248635996998003.Car-Rental-Destinations)[Orangeburg County Vacations](https://expedia.ca/Orangeburg-County.d553248635996998003.Destination-Travel-Guides) ![DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/a26d5a16-8cd2-405d-94ab-122a2f63e661.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Orangeburg County ![Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines](https://images.trvl-media.com/place/9953/712fb946-715a-4a74-8bf7-2c2bbd891023.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santee [](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/6058108/7d590932-d0d2-48e4-90bf-23f9acc0734e.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Orangeburg [](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) ![Eutawville, South Carolina sunset near Lake Marion with empty hammock on pine trees overlooking water landscape view at Fountain lake in spring evening with nobody](https://images.trvl-media.com/place/3000455924/dc128f90-2885-4acb-80b5-581201528ba2.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Eutawville [](https://expedia.ca/Eutawville-Hotels.d3000455924.Travel-Guide-Hotels) ![Aerial of Lake Marion Dam and Santee river in South Carolina providing drinking water, hydro power and recreational activities](https://images.trvl-media.com/place/3000456153/853d0648-5ca3-4a52-8d03-1e972c294c7d.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Vance [](https://expedia.ca/Vance-Hotels.d3000456153.Travel-Guide-Hotels) ![The Branchville Railroad Depot is listed on the National Register of Historic Places. The front of the structure now houses a museum/shrine of railroad memorabilia, including a caboose. It is open by appointment and children are welcome. Informal tours are led by John Norris, a retired railroad company executive. Admission is free but donations toward the upkeep of the museum are appreciated. Call (803) 707-1788 for information. The rear of the structure houses the Eatery at the Depot, which serves dinners on Thursday, Friday and Saturday evenings. Reservations are recommended but not required. Call (803) 274-8001 or (803) 515-](https://images.trvl-media.com/place/3000455875/43d228a3-3ea8-4c0d-b974-e33e83be19a7.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Branchville [](https://expedia.ca/Branchville-Hotels.d3000455875.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Feb 2 - Feb 3](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 3 - Feb 4](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-03&endDate=2026-02-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635996998003&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Orangeburg County hotels ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,425 reviews) "Always a great stay. Clean room, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $96 CA $107 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/40f69ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/99021580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) Santee 9.2/10 Wonderful (709 reviews) "Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $142 CA $157 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/f2adc30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c5155ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) Orangeburg 9.2/10 Wonderful (1,005 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $155 CA $172 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2557x3y3-7acc8337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2558x3y4-5a11a251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3837h2482x3y0-b2c385e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) Orangeburg 7.8/10 Good (1,007 reviews) "Clean rooms, good location, nice and polite staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenya CA $130 CA $144 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,005 reviews) "Our room was super clean, breakfast was good. And the hotel was nice and quiet." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) john CA $165 CA $183 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/fcd98400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) Santee 9.6/10 Exceptional (1,004 reviews) "Liked the size of the room, the staff and the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Virginia CA $169 CA $187 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a0deabe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/f12ce994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/71b46ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very good (717 reviews) "Overall a great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy CA $114 CA $127 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/2dd4e6c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/09406598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/2f324808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/c5e580c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) Orangeburg 8.0/10 Very good (568 reviews) "Nice room and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $124 CA $138 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/6fa02d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/5f0b6fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (998 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $161 CA $178 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/3941a18e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/e844503c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/ca4d16db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) Orangeburg 9.4/10 Exceptional (776 reviews) "Clean room, helpful and friendly front desk staff. Tasty breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARK CA $155 CA $172 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/2824d996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/0b55a618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) Santee 8.0/10 Very good (1,003 reviews) "Clean rooms, nice staff, decent breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale CA $130 CA $144 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/67da47be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ec6d0d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/044c704d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1,001 reviews) "Nice rooms and very good breakfast items." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $152 CA $169 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/d4b79aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/5f1ffd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) Orangeburg 8.2/10 Very good (1,001 reviews) "Enjoyed our stay " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Marie CA $91 CA $101 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/8229e487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/3ffa2f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/e5b64ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) Orangeburg 8.8/10 Excellent (695 reviews) "Nice roomy clean rooms, staff were great, indoor heated pool was nice accomadation for this time of year for the kids. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $143 CA $158 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/2e89db8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/c4341f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/ee5c02dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/600000/597800/597750/acfce64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Orangeburg by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) Orangeburg 8.6/10 Excellent (801 reviews) "Room was clean and comfortable. The employees were helpful and efficient. Overall good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) margaret CA $155 CA $172 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Orangeburg.h597750.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/50891687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/4c792a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee I-95 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) Santee 6.0/10 (471 reviews) "Clean room but needs an exhaust fan in the bathroom " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leesa CA $70 CA $85 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/b15e751d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/cfcbf535.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3ea4aa47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3e8501ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Orangeburg North [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) Orangeburg 6.0/10 (1,001 reviews) "The rooms were clean and staff was courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yojuana CA $74 CA $82 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/b4a7d12b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/fd9a2ff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/ca4e9299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham, Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) Orangeburg 6.8/10 (913 reviews) "Always a pleasure to stay, staff is very welcoming and the breakfast is a great plus!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $78 CA $87 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/5b7ee831.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) Santee 7.0/10 Good (694 reviews) "Nice quiet room and a delicious breakfast at a reasonable rate." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph B CA $79 CA $88 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Suite, 1 King Bed, Accessible, Smoking](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/81259c64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/6a21d794.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/706081d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15200/15145/3f3e2740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Orangeburg [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) Orangeburg 6.2/10 (633 reviews) "The room was very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judith CA $75 CA $83 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/Orangeburg-Hotels-Quality-Inn-Suites.h15145.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-16&endDate=2026-02-17®ionId=553248635996998003&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Orangeburg County, SC ### Showing deals for:**Feb 13 - Feb 15** ### Image gallery for The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. ![Property grounds](https://images.trvl-media.com/lodging/55000000/54180000/54171600/54171514/6ea35a79.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot. Eutawville **10/10**Exceptional (39 reviews) 10% off CA $208 CA $668 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=54171514&adults=2) ### Image gallery for Lake Marion - Majestic Big Water View! ![Exterior](https://images.trvl-media.com/lodging/105000000/104220000/104211700/104211609/d39bc1a3.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Lake Marion - Majestic Big Water View! Santee **10/10**Exceptional (9 reviews) 10% off CA $266 CA $973 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=104211609&adults=2) ### Image gallery for Beautiful brick home w/ large porch and 3 bedrooms ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/113000000/112530000/112528200/112528151/w1198h1600x0y0-8fa30947.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Beautiful brick home w/ large porch and 3 bedrooms Bowman **9.0/10**Wonderful (4 reviews) 10% off CA $202 CA $636 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=112528151&adults=2) ### Image gallery for Lake Side Condo Getaway ![Property grounds](https://images.trvl-media.com/lodging/104000000/103140000/103132400/103132374/694f5497.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Lake Side Condo Getaway Santee **8.4/10**Very good (8 reviews) 10% off CA $221 CA $721 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=103132374&adults=2) ### Image gallery for Waterfront Condo on Lake Marion ![Interior](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/67115d00.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Waterfront Condo on Lake Marion Santee **10/10**Exceptional (6 reviews) 10% off CA $472 CA $1,491 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=102018216&adults=2) ### Image gallery for Bells Marina & Resort ![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Bells Marina & Resort Eutawville **8.6/10**Excellent (86 reviews) 20% off CA $148 CA $329 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=91244689&adults=2) ### Image gallery for Country Resting Spot just off I95\. 12 miles west on hwy 6. ![Beach](https://images.trvl-media.com/lodging/108000000/107440000/107431600/107431587/3f704424.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Country Resting Spot just off I95\. 12 miles west on hwy 6. Elloree **9.4/10**Exceptional (22 reviews) 10% off CA $153 CA $455 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=107431587&adults=2) ### Image gallery for Travelodge by Wyndham Orangeburg ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Travelodge by Wyndham Orangeburg Orangeburg **8.2/10**Very good (1,001 reviews) 15% off CA $103 CA $229 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-15&selected=17380261&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ## Top Orangeburg County Hotel Reviews ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 10/10 Excellent "Check in was pleasant and quick. Room was exceptionally clean and fresh. Breakfast was delicious and employees were courteous and professional." [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "Facility and service were excellent" [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "Wonderful service nice staff clean hotel will definitely return next year " [](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 10/10 Excellent "Staff was excellent" [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![SpringHill Suites by Marriott Orangeburg](https://images.trvl-media.com/lodging/55000000/54940000/54931500/54931475/27e78d69_y.jpg) ### SpringHill Suites by Marriott Orangeburg 10/10 Excellent "Everything is good." [](https://expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 10/10 Excellent "The best!" [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg) ### Spark by Hilton Orangeburg 10/10 Excellent "Room was very clean. Front desk was helpful and courteous with quick check-in. Good breakfast" [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Super 8 by Wyndham, Orangeburg](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21_y.jpg) ### Super 8 by Wyndham, Orangeburg 10/10 Excellent "Room was very clean. Every one very nice." [](https://expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg) ### Comfort Inn & Suites Santee 10/10 Excellent "Check-in staff courteous and efficient. Clean, basic, comfortable room for a one night travel stay at good price. Good breakfast." [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Orangeburg County - [Santee Hotels ](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels) - [Orangeburg Hotels ](https://expedia.ca/Orangeburg-Hotels.d6058108.Travel-Guide-Hotels) - [Eutawville Hotels ](https://expedia.ca/Eutawville-Hotels.d3000455924.Travel-Guide-Hotels) - [Holly Hill Hotels ](https://expedia.ca/Holly-Hill-Hotels.d3000455972.Travel-Guide-Hotels) - [Vance Hotels ](https://expedia.ca/Vance-Hotels.d3000456153.Travel-Guide-Hotels) - [Bowman Hotels ](https://expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Neeses Hotels ](https://expedia.ca/Neeses-Hotels.d3000456036.Travel-Guide-Hotels) - [Whetsell Hotels ](https://expedia.ca/Whetsell-Hotels.d553248635974902828.Travel-Guide-Hotels) - [North Hotels ](https://expedia.ca/North-Hotels.d553248634999378506.Travel-Guide-Hotels) - [Rowesville Hotels ](https://expedia.ca/Rowesville-Hotels.d3000353220.Travel-Guide-Hotels) - [Cope Hotels ](https://expedia.ca/Cope-Hotels.d3000455896.Travel-Guide-Hotels) - [Cordova Hotels ](https://expedia.ca/Cordova-Hotels.d553248634998610573.Travel-Guide-Hotels) - [Norway Hotels ](https://expedia.ca/Norway-Hotels.d553248634998816179.Travel-Guide-Hotels) - [Woodford Hotels ](https://expedia.ca/Woodford-Hotels.d553248634998789873.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Santee State Park ](https://expedia.ca/Santee-State-Park-Hotels.0-l6140632-0.Travel-Guide-Filter-Hotels) - [Hotels near South Carolina State University ](https://expedia.ca/South-Carolina-State-University-Hotels.0-l6193863-0.Travel-Guide-Filter-Hotels) - [Hotels near Santee Cooper Country Club ](https://expedia.ca/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) - [Hotels near Santee National Golf Club ](https://expedia.ca/Santee-National-Golf-Club-Hotels.0-l553248621532654897-0.Travel-Guide-Filter-Hotels) - [Hotels near Edisto Memorial Gardens ](https://expedia.ca/Edisto-Memorial-Gardens-Hotels.0-l553248621532654892-0.Travel-Guide-Filter-Hotels) - [Hotels near I.P. Stanback Museum & Planetarium ](https://expedia.ca/IP-Stanback-Museum-Planetarium-Hotels.0-l553248621561867626-0.Travel-Guide-Filter-Hotels) - [Hotels near Williams Brice Stadium ](https://expedia.ca/Williams-Brice-Stadium-Hotels.0-l6193698-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Orangeburg County - [Vacation Homes in Orangeburg County ](https://expedia.ca/Orangeburg-County-Private-Vacation-Homes.d553248635996998003-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Orangeburg County ](https://expedia.ca/Orangeburg-County-Apartments.d553248635996998003-aaApartments.Travel-Guide-Accommodation) - [Cottages in Orangeburg County ](https://expedia.ca/Orangeburg-County-Cottages.d553248635996998003-aaCottages.Travel-Guide-Accommodation) - [Motels in Orangeburg County ](https://expedia.ca/Orangeburg-County-Motels.d553248635996998003-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in Orangeburg County ](https://expedia.ca/Orangeburg-County-Cabins.d553248635996998003-aaCabins.Travel-Guide-Accommodation) - [Condo Rentals in Orangeburg County ](https://expedia.ca/Orangeburg-County-Condos.d553248635996998003-aaCondos.Travel-Guide-Accommodation) - [Farmstay in Orangeburg County ](https://expedia.ca/Orangeburg-County-Agritourism.d553248635996998003-aaAgritourism.Travel-Guide-Accommodation) - [Resorts in Orangeburg County ](https://expedia.ca/Orangeburg-County-Resort-Hotels.d553248635996998003-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in Orangeburg County ](https://expedia.ca/Orangeburg-County-Apart-Hotels.d553248635996998003-aaApartHotels.Travel-Guide-Accommodation) - [RV Parks in Orangeburg County ](https://expedia.ca/Orangeburg-County-RV-Parks.d553248635996998003-aaRVParks.Travel-Guide-Accommodation) - [Guest Houses in Orangeburg County ](https://expedia.ca/Orangeburg-County-Guest-Houses.d553248635996998003-aaGuestHouses.Travel-Guide-Accommodation) - [Lodges in Orangeburg County ](https://expedia.ca/Orangeburg-County-Lodges.d553248635996998003-aaLodges.Travel-Guide-Accommodation) - [Country Houses in Orangeburg County ](https://expedia.ca/Orangeburg-County-Country-House.d553248635996998003-aaCountryHouse.Travel-Guide-Accommodation) - [B&B in Orangeburg County ](https://expedia.ca/Orangeburg-County-Bed-And-Breakfast.d553248635996998003-aaBedAndBreakfast.Travel-Guide-Accommodation) ### Hotels near Orangeburg County Airports - [Columbia Metropolitan Airport Hotels ](https://expedia.ca/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels) - [Charleston Intl. Airport Hotels ](https://expedia.ca/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Baymont by Wyndham Santee ](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) - [Tru By Hilton Santee ](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) - [Tru by Hilton Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) - [Hampton Inn Santee-I-95 ](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) - [Fairfield Inn & Suites by Marriott Santee ](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) - [Spark by Hilton Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) - [SpringHill Suites by Marriott Orangeburg ](https://expedia.ca/Orangeburg-Hotels-SpringHill-Suites-Orangeburg.h54931475.Hotel-Information) - [Super 8 by Wyndham, Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) - [Travelodge by Wyndham Orangeburg ](https://expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) - [Best Western Plus Santee Inn ](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) [See a list of all hotels in Orangeburg County](https://expedia.ca/All-Orangeburg-County-Hotels.d553248635996998003.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Orangeburg County on Expedia.com ](https://www.expedia.com/Destinations-In-Orangeburg-County.d553248635996998003.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Hotels in Charleston Historic District](https://expedia.ca/Charleston-Historic-District-Charleston-Hotels.0-n6057948-0.Travel-Guide-Filter-Hotels) - [Middleton Place hotels](https://expedia.ca/Middleton-Place-Hotels.0-l6082609-0.Travel-Guide-Filter-Hotels) - [French Quarter Family Hotels](https://expedia.ca/French-Quarter-Charleston-Hotels-Family-Hotel.0-n3000663061-0-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels in Sea Pines](https://expedia.ca/Sea-Pines-Hilton-Head-Island-Hotels.0-n553248635976473337-0.Travel-Guide-Filter-Hotels) - [Hotels with Tennis Courts in Charleston County](https://expedia.ca/Destinations-In-Charleston-County-Hotels-With-Tennis-Courts.0-0-d553248635083907096-tHotelswithTennisCourts.Hotel-Filter-Destinations) - [Ski Hotels in Charleston County](https://expedia.ca/Destinations-In-Charleston-County-Ski-Hotel.0-0-d553248635083907096-tSkiHotel.Hotel-Filter-Destinations) - [Tupelo Bay Golf Center hotels](https://expedia.ca/Tupelo-Bay-Golf-Center-Hotels.0-l6290595-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Spartanburg County](https://expedia.ca/Destinations-In-Spartanburg-County-Cheap-Hotels.0-0-d553248635976433422-tCheapHotels.Hotel-Filter-Destinations) - [Hotels in Downtown Charleston](https://expedia.ca/Downtown-Charleston-Charleston-Hotels.0-n553248633938969537-0.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in Charleston County](https://expedia.ca/Destinations-In-Charleston-County-Hotels-With-Free-Parking.0-0-d553248635083907096-tHotelswithFreeParking.Hotel-Filter-Destinations) - [Golden Mile All Inclusive Resorts and Hotels](https://expedia.ca/Golden-Mile-Myrtle-Beach-Hotels-All-Inclusive-Hotel.0-n553248635976471063-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) Cars - [Car rental Myrtle Beach Airport (MYR)](https://expedia.ca/Car-Rentals-In-Myrtle-Beach-Intl.d5396813.Car-Rental-Guide) - [Car rental Anderson Airport (AND)](https://expedia.ca/Car-Rentals-In-Anderson-County-Regional.d6026161.Car-Rental-Guide) - [Car rental Florence Airport (FLO)](https://expedia.ca/Car-Rentals-In-Florence-Regional.d6027805.Car-Rental-Guide) - [Dollar Rent A Car Car Rentals In Hilton Head Island](https://expedia.ca/Dollar-Rent-A-Car-Car-Rentals-In-Hilton-Head-Island.d6028293-c43.Car-Rental-Guide-Suppliers) - [Car rental North Charleston Airport (CHS)](https://expedia.ca/Car-Rentals-In-Charleston-Intl.d5457987.Car-Rental-Guide) Activities - [Things to do in Horry County](https://expedia.ca/Things-To-Do-In-Horry-County.d553248635083907335.Travel-Guide-Activities) Packages - [USS Yorktown](https://expedia.ca/USS-Yorktown-Mount-Pleasant.d6082607.Vacation-Attraction) - [Magnolia Plantation and Gardens](https://expedia.ca/Magnolia-Plantation-And-Gardens-Charleston.d6082613.Vacation-Attraction) - [Myrtle Beach State Park](https://expedia.ca/Myrtle-Beach-State-Park-Myrtle-Beach.d6079991.Vacation-Attraction) - [Fred W. Symmes Chapel](https://expedia.ca/Fred-W-Symmes-Chapel-Cleveland.d553248621532656718.Vacation-Attraction) - [Coastal Grand Mall](https://expedia.ca/Coastal-Grand-Mall-Myrtle-Beach.d553248635261002225.Vacation-Attraction) - [Barefoot Landing](https://expedia.ca/Barefoot-Landing-North-Myrtle-Beach.d6161407.Vacation-Attraction) - [Ripley's Aquarium](https://expedia.ca/Ripleys-Aquarium-Myrtle-Beach.d6079963.Vacation-Attraction) - [Huntington Beach State Park](https://expedia.ca/Huntington-Beach-State-Park-Murrells-Inlet.d6238108.Vacation-Attraction) - [Broadway at the Beach](https://expedia.ca/Broadway-At-The-Beach-Myrtle-Beach.d6079959.Vacation-Attraction) - [Family Kingdom Amusement Park](https://expedia.ca/Family-Kingdom-Amusement-Park-Myrtle-Beach.d6079999.Vacation-Attraction) General - [Visit Vanderhorst Plantation](https://expedia.ca/Kiawah-Island-Vanderhorst-Plantation.dx553248635976471182) - [Visit Cherry Grove Beach](https://expedia.ca/North-Myrtle-Beach-Cherry-Grove-Beach.dx553248621561867974) - [Visit Downtown Myrtle Beach](https://expedia.ca/Myrtle-Beach-Downtown-Myrtle-Beach.dx553248633938969374) ## Frequently asked questions ### How much do hotels in Orangeburg County cost? ### When is the best time to go to Orangeburg County? ### How can I find cheap hotels in Orangeburg County? ### What are the best hotels in Orangeburg County for families? ### Why should I book my Orangeburg County hotel with Expedia? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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