Defiance Vacation Packages

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Your Defiance Vacation

Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a vacation package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Center and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance vacation is just a few clicks away with Expedia.

Top Defiance Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Principal Hotel

The Principal Hotel

3.5 out of 5
per person
Aug 23 - Aug 27
found 19 hours ago
Roundtrip non-stop flight included
Seattle (SEA) to St. Louis (STL)
9.8/10 Exceptional! (88 reviews)
Unique place to stay. Amazing rooms. Amazing town. Highly recommend

Reviewed on Jul. 20, 2025

The Cheshire

The Cheshire

4 out of 5
per person
Aug 23 - Aug 27
found 19 hours ago
Roundtrip non-stop flight included
Seattle (SEA) to St. Louis (STL)
8.6/10 Excellent! (1,000 reviews)
The Cheshire was really cute and the decor was fun! Friendly staff and cool restaurants on site.

Reviewed on Jul. 20, 2025

Ballpark Apartments by Barsala

Ballpark Apartments by Barsala

4 out of 5
Downtown St. Louis
per person
Aug 23 - Aug 27
found 19 hours ago
Roundtrip non-stop flight included
Seattle (SEA) to St. Louis (STL)
7.4/10 Good! (9 reviews)
It's a great location, right across from the Ballpark. It is a fairly spartan apartment set-up, with concrete floors.. a little surprising? Parking is on the street or in a pay lot.

Reviewed on Jun. 8, 2025

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
Central West End
per person
Aug 23 - Aug 27
found 19 hours ago
Roundtrip non-stop flight included
Seattle (SEA) to St. Louis (STL)
9/10 Wonderful! (1,006 reviews)
The valet people were amazing. Brenda the hostess was so friendly to talk to!!

Reviewed on Jul. 22, 2025

Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
per person
Aug 23 - Aug 27
found 19 hours ago
Roundtrip non-stop flight included
Seattle (SEA) to St. Louis (STL)
8/10 Very Good! (1,006 reviews)
We stayed overnight before our flight. We enjoyed the pool area and quiet room. It is easy to get to the airport.

Reviewed on Jul. 19, 2025

Ready to book your vacation to Defiance?

 

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Defiance Hotel Deals

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is CA $128 per night from Aug 3 to Aug 4
CA $128
CA $148 total
Aug 3 - Aug 4
includes taxes & fees
8.4/10 Very Good! (1,023 reviews)
"For being a full hotel it was pretty quiet"

Reviewed on Jul. 21, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $159 per night from Jul 27 to Jul 28
CA $159
CA $206 total
Jul 27 - Jul 28
includes taxes & fees
8.2/10 Very Good! (2,003 reviews)
"Loved it A+"

Reviewed on Jul. 22, 2025

Hollywood Casino & Hotel St. Louis
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 out of 5
1970 Craig Rd, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $93 per night from Aug 10 to Aug 11
CA $93
CA $107 total
Aug 10 - Aug 11
includes taxes & fees
4.4/10 (1,011 reviews)
Needs cleaning
"We where given a dirty room at 1st but got another room..."

Reviewed on Jul. 18, 2025

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
See all 841 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Discover the most popular places to visit in Defiance

Busch Stadium

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
Gateway Arch featuring modern architecture, a city and a skyscraper

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

What to do in Defiance

St Louis: City Museum General Admission Ticket

St Louis: City Museum General Admission Ticket

CA $30
per adult
96% of travellers recommend
St Louis: City Museum General Admission Ticket
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

CA $44
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
St Louis Self-Guided Driving and Walking Audio Tour

St Louis Self-Guided Driving and Walking Audio Tour

CA $23
per traveller
St Louis Self-Guided Driving and Walking Audio Tour
See all activities in Defiance

Frequently asked questions

How much does a Defiance vacation package cost?
You can grab a vacation package to this destination from CA $499 on Expedia. However, how much your vacation to Defiance costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Defiance?
The off-season is the best time to travel to Defiance if you're hoping to keep costs down. Another tip for getting cheap Defiance vacation packages? Avoid visiting during public holidays and any major festivals.
How many days is enough for Defiance?
The ideal duration for your Defiance vacation depends on what you'd like to do and see. Usually, a few days to a week will give you time to go to all the major attractions and discover some hidden spots along the way.
How to find the best Defiance package deals?
Begin your search for a Defiance package deal by entering your travel dates and destination under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Defiance package deal straight away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Defiance getaway off to a flying start.
Is it cheaper to book a Defiance vacation as a package?
You can enjoy significant savings on your next Defiance retreat by booking a personalized vacation package. Check the "Package" heading, then enter your destination and travel dates to browse some great hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Defiance?
If you've got your Defiance vacation dates locked in, book as early as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are great for travelling on a whim.
How to plan a trip to Defiance?

  1. Choose your dates: The things you'd like to do in Defiance and your favourite season can help you decide when to get away.
  2. Set a budget: Factor in expenses like flights, transportation and food when working out how much to save for your trip to Defiance. Then, pick a property that works with your budget, whether that's a low-cost stay or a lavish retreat.
  3. Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Defiance. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a tailored Defiance vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.