Defiance Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Defiance Vacation
Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a vacation package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Center and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance vacation is just a few clicks away with Expedia.
Top Defiance Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel
Delmar Loop
CA $1,087
per person
Oct 3 - Oct 6
found 1 day ago
Roundtrip non-stop flight included
Winnipeg (YWG) to St. Louis (STL)
9/10 Wonderful! (2,013 reviews)
Loved the hotel. The only downside was the street noise from midnight-3 am even on the 7th floor. Nothing the hotel could have done as there were a bunch of people on the street.
Reviewed on Aug 20, 2026
Ready to book your vacation to Defiance?
Defiance Hotel Deals
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
CA $138
CA $202 total
Aug 31 - Sep 1
includes taxes & fees
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
CA $130
CA $150 total
Sep 3 - Sep 4
includes taxes & fees
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
CA $204
CA $261 total
Sep 7 - Sep 8
includes taxes & fees
8.6/10 Excellent! (1,041 reviews)
"Room was a great size for the money. Hotel was clean and quiet and easy to access from the garage. Great pool as well."
Reviewed on Aug 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Defiance attractions
August A. Busch Memorial Conservation Area
8.6/10 (7 reviews)
Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants.
Photo by Pages of Travel
Chandler Hill Vineyards
7.8/10 (7 reviews)
You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savor the top-notch restaurants.
Historic Daniel Boone Home and Heritage Center
9.6/10 (4 reviews)
You can spend time exploring the galleries in Historic Daniel Boone Home and Heritage Center in Defiance. Stroll along the area's lakeside or simply enjoy its wineries.
Sugar Creek Winery
8.0/10 (1 review)
You can enjoy a tasting or tour at Sugar Creek Winery during your travels to Defiance. While in this romantic area, you can savor the top-notch restaurants.
Yellow Farmhouse Winery
You can enjoy a tasting or tour at Yellow Farmhouse Winery during your travels to Defiance. While in this family-friendly area, you can savor the top-notch restaurants.
Matson Hill Park Trailhead
You can take time to visit Matson Hill Park Trailhead during your travels to Defiance. While you're in the area, wander around the parks.
Broemmelsiek Park
Broemmelsiek Park is just one of the places to see in Defiance, so why not enjoy the other things to explore during your travels? Amble around this family-friendly area's gardens or experience its festivals.
Hamburg Trail Trailhead
You can take time to visit Hamburg Trail Trailhead during your travels to Hamburg.
What to do in Defiance
St. Louis Ghost Tour: Sinister Sins & Shadows
CA $34
per adult
100% of travellers recommend
StL's Signature "Sights and Bites" - Private Tour in St. Louis
CA $246
per adult
Lemp Haunted Neighborhood Walking Tour
CA $35
per adult
84% of travellers recommend
Frequently asked questions
How much does a Defiance vacation package cost?
You can grab a vacation package to this destination from CA $997 on Expedia. However, how much your vacation to Defiance costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Defiance?
The off-season is the best time to travel to Defiance if you're hoping to keep costs down. Another tip for getting cheap Defiance vacation packages? Avoid visiting during public holidays and any major festivals.
How many days is enough for Defiance?
The ideal duration for your Defiance vacation depends on what you'd like to do and see. Usually, a few days to a week will give you time to go to all the major attractions and discover some hidden spots along the way.
How to find the best Defiance package deals?
Begin your search for a Defiance package deal by entering your travel dates and destination under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Defiance package deal straight away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Defiance getaway off to a flying start.
Is it cheaper to book a Defiance vacation as a package?
You can enjoy significant savings on your next Defiance retreat by booking a personalized vacation package. Check the "Package" heading, then enter your destination and travel dates to browse some great hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Defiance?
If you've got your Defiance vacation dates locked in, book as early as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are great for travelling on a whim.
How to plan a trip to Defiance?
- Choose your dates: The things you'd like to do in Defiance and your favourite season can help you decide when to get away.
- Set a budget: Factor in expenses like flights, transportation and food when working out how much to save for your trip to Defiance. Then, pick a property that works with your budget, whether that's a low-cost stay or a lavish retreat.
- Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Defiance. Then, estimate how long you'll need for each, as well as any travel time.
- Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a tailored Defiance vacation package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
