Title: The 10 Best Hotels Near Appleton Medical Center, Appleton from CA $107 | Expedia.ca [Appleton Travel Guide](https://expedia.ca/Appleton.dx6059808)[Vacation Rentals in Appleton](https://expedia.ca/Appleton-Vacation-Rentals.d6059808.Travel-Guide-VacationRentals)[Flights to Appleton](https://expedia.ca/Cheap-Flights-To-Appleton.d6059808.Travel-Guide-Flights)[Things to do in Appleton](https://expedia.ca/Things-To-Do-In-Appleton.d6059808.Travel-Guide-Activities)[Appleton Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Appleton-Medical-Center.d6181681.Car-Rental-Guide)[Appleton Medical Center Vacations](https://expedia.ca/Appleton-Medical-Center-Appleton.d6181681.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Appleton Medical Center, Appleton from CA $107 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=6181681&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=6181681&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6181681&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6181681&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Appleton Medical Center hotels ![Suite, 1 King Bed, Non Smoking, Jetted Tub (Walk-in Shower;with Sofabed)](https://images.trvl-media.com/lodging/1000000/990000/986100/986058/75e8acc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Jetted Tub (Living Room;with Sofabed)](https://images.trvl-media.com/lodging/1000000/990000/986100/986058/d9c34d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/990000/986100/986058/0bb9ebc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Jetted Tub (Living Room;with Sofabed) | Bathroom](https://images.trvl-media.com/lodging/1000000/990000/986100/986058/c9d75836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CopperLeaf Boutique Hotel & Spa, BW Premier Collection [](https://www.expedia.ca/Appleton-Hotels-CopperLeaf-Boutique-Hotel-Spa.h986058.Hotel-Information) 2.2 km from Appleton Medical Center 9.4/10 Exceptional (1004) "Such a cute place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $153 CA $177 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Appleton-Hotels-CopperLeaf-Boutique-Hotel-Spa.h986058.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/20000000/19530000/19520500/19520449/9111d9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19530000/19520500/19520449/d0f5a000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19530000/19520500/19520449/92a9a3b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19530000/19520500/19520449/53371df5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Appleton Riverfront [](https://www.expedia.ca/Appleton-Hotels-Courtyard-By-Marriott-Appleton-Riverfront.h19520449.Hotel-Information) 2.1 km from Appleton Medical Center 9.4/10 Exceptional (432) "We love this spot! The suites are sizable, the mattresses are outstanding and the scenery around it is beautiful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn CA $209 CA $242 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Appleton-Hotels-Courtyard-By-Marriott-Appleton-Riverfront.h19520449.Hotel-Information) ![Premium bedding, in-room safe, desk, rollaway beds](https://images.trvl-media.com/lodging/1000000/40000/36900/36824/w3840h2567x0y3-a8b130aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, sports bar](https://images.trvl-media.com/lodging/1000000/40000/36900/36824/w3996h2742x4y0-8c740b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/40000/36900/36824/27277f36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/36900/36824/2ade2a19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Appleton Paper Valley [](https://www.expedia.ca/Appleton-Hotels-Hilton-Appleton-Paper-Valley.h36824.Hotel-Information) 2.2 km from Appleton Medical Center 8.6/10 Excellent (1005) "Hotel is clean amenities were nice and it was very quiet. Excellent area around the hotel and easy to find dining and drinking options." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristin CA $123 CA $142 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Appleton-Hotels-Hilton-Appleton-Paper-Valley.h36824.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746278/fbdf923a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast for a fee](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746278/32336629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746278/73237583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, desk](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746278/47c0675f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Appleton [](https://www.expedia.ca/Appleton-Hotels-Cambria-Hotel-Appleton.h1746278.Hotel-Information) 3.2 km from Appleton Medical Center 8.8/10 Excellent (983) "Comfy bed!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $125 CA $145 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Appleton-Hotels-Cambria-Hotel-Appleton.h1746278.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1400000/1397400/1397335/5ec18f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1400000/1397400/1397335/25f29475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1400000/1397400/1397335/3783ce81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1400000/1397400/1397335/98ef01a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Appleton North/Little Chute [](https://www.expedia.ca/Appleton-Hotels-AmericInn-By-Wyndham-Appleton.h1397335.Hotel-Information) 3.1 km from Appleton Medical Center 7.6/10 Good (1002) "It was a great stay...." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $98 CA $114 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Appleton-Hotels-AmericInn-By-Wyndham-Appleton.h1397335.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/40000000/39040000/39030500/39030418/f965718b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/40000000/39040000/39030500/39030418/f6e1dfe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/40000000/39040000/39030500/39030418/22f4b0e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/40000000/39040000/39030500/39030418/247795f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Appleton [](https://www.expedia.ca/Appleton-Hotels-Fairfield-Inn-Suites-By-Marriott-Appleton.h39030418.Hotel-Information) 6.1 km from Appleton Medical Center 9.6/10 Exceptional (230) "Front desk/check in was great! Kind and informative. Thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $123 CA $142 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Appleton-Hotels-Fairfield-Inn-Suites-By-Marriott-Appleton.h39030418.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20300/20223/eec64db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/20300/20223/6dc3011a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/20300/20223/e37281ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/20300/20223/374179cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Appleton-Fox River Mall Area [](https://www.expedia.ca/Appleton-Hotels-Hampton-Inn-Appleton-Fox-River-Mall-Area.h20223.Hotel-Information) 6 km from Appleton Medical Center 9.4/10 Exceptional (1006) "Great place to stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Daniel Patrick CA $110 CA $127 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Appleton-Hotels-Hampton-Inn-Appleton-Fox-River-Mall-Area.h20223.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/65000000/64060000/64050200/64050133/c0fc0b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/65000000/64060000/64050200/64050133/d4981b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa Sleeper, Accessible Tub, Kitchenette, Non Smoking | Private kitchenette](https://images.trvl-media.com/lodging/65000000/64060000/64050200/64050133/7549b91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/65000000/64060000/64050200/64050133/ed5e801e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Hotel & Suites-Little Chute [](https://www.expedia.ca/Little-Chute-Hotels-Cobblestone-Hotel-Suites-Little-Chute.h64050133.Hotel-Information) 6.2 km from Appleton Medical Center 9.4/10 Exceptional (661) "Good place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $101 CA $117 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Little-Chute-Hotels-Cobblestone-Hotel-Suites-Little-Chute.h64050133.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36250000/36247200/36247154/w3839h2546x0y16-988a9e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/37000000/36250000/36247200/36247154/517b9d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36250000/36247200/36247154/a246708e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/37000000/36250000/36247200/36247154/c7b2f56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Appleton [](https://www.expedia.ca/Appleton-Hotels-Home2-Suites-By-Hilton-Appleton.h36247154.Hotel-Information) 7.3 km from Appleton Medical Center 9.6/10 Exceptional (653) "Clean room, up to date, and accommodating staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pame CA $140 CA $162 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Appleton-Hotels-Home2-Suites-By-Hilton-Appleton.h36247154.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36400000/36392300/36392299/db7ebf90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36400000/36392300/36392299/854a5d6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36400000/36392300/36392299/612d955a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36400000/36392300/36392299/a0e9c5be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Appleton by IHG [](https://www.expedia.ca/Appleton-Hotels-Holiday-Inn-Appleton.h36392299.Hotel-Information) 6.5 km from Appleton Medical Center 9.2/10 Wonderful (490) "Was nice and warm" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesus CA $131 CA $151 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Appleton-Hotels-Holiday-Inn-Appleton.h36392299.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25900/25833/74c5f361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/30000/25900/25833/5a2dfc0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25900/25833/adf210e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/30000/25900/25833/952201e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Appleton [](https://www.expedia.ca/Appleton-Hotels-DoubleTree-By-Hilton-Appleton.h25833.Hotel-Information) 6.2 km from Appleton Medical Center 9.0/10 Wonderful (1387) "Nice shower" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $123 CA $142 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Appleton-Hotels-DoubleTree-By-Hilton-Appleton.h25833.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/17800/17761/49cb275f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17800/17761/77392a3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17800/17761/6f899cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/17800/17761/f11d19ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Appleton Airport [](https://www.expedia.ca/Appleton-Hotels-Comfort-Suites-Appleton-Airport.h17761.Hotel-Information) 5.5 km from Appleton Medical Center 8.8/10 Excellent (919) "Clean room and great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeanine CA $141 CA $163 total includes taxes & fees Jan 14 - Jan 15, 2026 [](https://www.expedia.ca/Appleton-Hotels-Comfort-Suites-Appleton-Airport.h17761.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43200/43138/03c4926a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/43200/43138/8a55c756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/43200/43138/3c7cf5f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43200/43138/76402f63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area [](https://www.expedia.ca/Appleton-Hotels-Country-Inn-Suites-By-Radisson.h43138.Hotel-Information) 6 km from Appleton Medical Center 8.8/10 Excellent (1004) "All around nice place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peggy CA $113 CA $131 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Appleton-Hotels-Country-Inn-Suites-By-Radisson.h43138.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/400/312/f0339ce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/10000/400/312/bb2c7d92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/400/312/01e97c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/400/312/ba33df8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Appleton Downtown [](https://www.expedia.ca/Appleton-Hotels-Clarion-Inn.h312.Hotel-Information) 5 km from Appleton Medical Center 8.4/10 Very good (1003) "Staff is very nice and accommodating we stay there every year." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $105 CA $122 total includes taxes & fees Jan 12 - Jan 13, 2026 [](https://www.expedia.ca/Appleton-Hotels-Clarion-Inn.h312.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/920000/914000/913914/ebbf8f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/920000/914000/913914/2cb6d701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Accessible (MOBILITY) | Living area](https://images.trvl-media.com/lodging/1000000/920000/914000/913914/c0b174ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/914000/913914/f896ba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Appleton by IHG [](https://www.expedia.ca/Appleton-Hotels-Candlewood-Suites-Appleton.h913914.Hotel-Information) 6.5 km from Appleton Medical Center 8.8/10 Excellent (475) "Perfect for a long staying" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) eral CA $96 CA $111 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Appleton-Hotels-Candlewood-Suites-Appleton.h913914.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/12700/12688/e29dcbf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12700/12688/d8c481af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/12700/12688/e1082fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/12700/12688/ea89aa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham Appleton [](https://www.expedia.ca/Appleton-Hotels-AmericInn-By-Wyndham-Appleton-Airport.h12688.Hotel-Information) 6.1 km from Appleton Medical Center 8.6/10 Excellent (1007) "Great room at a great price!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $109 CA $126 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Appleton-Hotels-AmericInn-By-Wyndham-Appleton-Airport.h12688.Hotel-Information) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/20000/12800/12761/9d02a346.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12800/12761/9d6222d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12800/12761/01b03830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12800/12761/39efd787.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Appleton Airport - Fox River Mall Area [](https://www.expedia.ca/Appleton-Hotels-Residence-Inn-Appleton.h12761.Hotel-Information) 6.2 km from Appleton Medical Center 8.6/10 Excellent (199) "Friendly employees, great amenities, room had everything needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Axel CA $92 CA $107 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Appleton-Hotels-Residence-Inn-Appleton.h12761.Hotel-Information) ![Traditional Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/50000/43200/43147/fea37208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Brewpub](https://images.trvl-media.com/lodging/1000000/50000/43200/43147/115bd8bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43200/43147/8b4f97b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Brewpub](https://images.trvl-media.com/lodging/1000000/50000/43200/43147/d8f6f8a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton Appleton [](https://www.expedia.ca/Appleton-Hotels-Four-Points-By-Sheraton-Appleton.h43147.Hotel-Information) 6.3 km from Appleton Medical Center 8.6/10 Excellent (1001) "Room was very clean, staff was really helpful. Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Calvert CA $135 CA $156 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Appleton-Hotels-Four-Points-By-Sheraton-Appleton.h43147.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1700000/1691900/1691860/98124610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV](https://images.trvl-media.com/lodging/2000000/1700000/1691900/1691860/41e839cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1700000/1691900/1691860/785a2ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1700000/1691900/1691860/c1b5c4f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Appleton [](https://www.expedia.ca/Appleton-Hotels-Wyndham-Garden-Appleton.h1691860.Hotel-Information) 6.2 km from Appleton Medical Center 8.4/10 Very good (1002) "My room was clean, the place is quiet, the food was great and the staff were very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shameaka CA $147 CA $170 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Appleton-Hotels-Wyndham-Garden-Appleton.h1691860.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/115000000/114970000/114964900/114964879/5aaf2322.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/115000000/114970000/114964900/114964879/6c232fd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/115000000/114970000/114964900/114964879/831aee29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed (Extended Stay | Chair)](https://images.trvl-media.com/lodging/115000000/114970000/114964900/114964879/6b8fa15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### GrandStay Hotel & Suites Kaukauna [](https://www.expedia.ca/Kaukauna-Hotels-GrandStay-Hotel-Suites-Kaukauna.h114964879.Hotel-Information) 9.7 km from Appleton Medical Center 9.4/10 Exceptional (41) "Very clean and convenient for Green Bay. staff were friendly and courteous. A nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $123 CA $142 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Kaukauna-Hotels-GrandStay-Hotel-Suites-Kaukauna.h114964879.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-30&endDate=2025-12-31®ionId=6181681&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Appleton Medical Center Hotel Reviews ![Baymont by Wyndham Appleton](https://images.trvl-media.com/lodging/19000000/18570000/18566900/18566872/3efa7195_y.jpg) ### Baymont by Wyndham Appleton 10/10 Excellent "Clean and peaceful ❤️" [](https://expedia.ca/Appleton-Hotels-Baymont-By-Wyndham-Appleton.h18566872.Hotel-Information) ![Hilton Appleton Paper Valley](https://images.trvl-media.com/lodging/1000000/40000/36900/36824/w3840h2567x0y3-a8b130aa_y.jpg) ### Hilton Appleton Paper Valley 10/10 Excellent "Hotel is clean amenities were nice and it was very quiet. Excellent area around the hotel and easy to find dining and drinking options." [](https://expedia.ca/Appleton-Hotels-Hilton-Appleton-Paper-Valley.h36824.Hotel-Information) ![DoubleTree by Hilton Appleton](https://images.trvl-media.com/lodging/1000000/30000/25900/25833/74c5f361_y.jpg) ### DoubleTree by Hilton Appleton 10/10 Excellent "Yes" [](https://expedia.ca/Appleton-Hotels-DoubleTree-By-Hilton-Appleton.h25833.Hotel-Information) ![Wyndham Garden Appleton](https://images.trvl-media.com/lodging/2000000/1700000/1691900/1691860/98124610_y.jpg) ### Wyndham Garden Appleton 10/10 Excellent "My room was clean, the place is quiet, the food was great and the staff were very nice. " [](https://expedia.ca/Appleton-Hotels-Wyndham-Garden-Appleton.h1691860.Hotel-Information) ![Comfort Suites Appleton Airport](https://images.trvl-media.com/lodging/1000000/20000/17800/17761/49cb275f_y.jpg) ### Comfort Suites Appleton Airport 10/10 Excellent "Very nice hotel. The decorations and decor was pleasant, and welcoming. Room was clean and comfortable continental breakfast had hot eggs, sausage and other delicious items. We did not get a chance to use the pool or hot tub, but we checked them out and they looked inviting! There a children’s slide and play area. We would definitely come back the the Comfort Suites." [](https://expedia.ca/Appleton-Hotels-Comfort-Suites-Appleton-Airport.h17761.Hotel-Information) ![AmericInn by Wyndham Appleton Downtown](https://images.trvl-media.com/lodging/1000000/10000/400/312/f0339ce1_y.jpg) ### AmericInn by Wyndham Appleton Downtown 10/10 Excellent "Check in was a breeze. Staff were friendly. Room clean, so was the hot tub and pool area. Fantastic for a quick overnight stay." [](https://expedia.ca/Appleton-Hotels-Clarion-Inn.h312.Hotel-Information) ![Holiday Inn Appleton by IHG](https://images.trvl-media.com/lodging/37000000/36400000/36392300/36392299/db7ebf90_y.jpg) ### Holiday Inn Appleton by IHG 10/10 Excellent "Friendly, helpful staff. Conveniently located! My go-to in Appleton! " [](https://expedia.ca/Appleton-Hotels-Holiday-Inn-Appleton.h36392299.Hotel-Information) ![AmericInn by Wyndham Appleton North/Little Chute](https://images.trvl-media.com/lodging/2000000/1400000/1397400/1397335/51372f82_y.jpg) ### AmericInn by Wyndham Appleton North/Little Chute 10/10 Excellent "Didn't have breakfast " [](https://expedia.ca/Appleton-Hotels-AmericInn-By-Wyndham-Appleton.h1397335.Hotel-Information) ![CopperLeaf Boutique Hotel & Spa, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/990000/986100/986058/75e8acc1_y.jpg) ### CopperLeaf Boutique Hotel & Spa, BW Premier Collection 10/10 Excellent "Awesome location " [](https://expedia.ca/Appleton-Hotels-CopperLeaf-Boutique-Hotel-Spa.h986058.Hotel-Information) ## Hotels near other Appleton Medical Center attractions ### Erb Park 4.1/5 (43 reviews) After visiting Erb Park, make a plan to see the other sights and activities in Appleton. Attend a sporting event or visit the shops in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6179118) ### Super Bowl Family Entertainment Center You can take time to visit Super Bowl Family Entertainment Center during your travels to Appleton. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=937304467712622592) ### Appleton Memorial Park 4.0/5 (58 reviews) Appleton Memorial Park is just one of the places to see in Appleton, so why not enjoy the other things to explore during your travels? Attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6179077) ### History Museum at the Castle You can spend an afternoon exploring the galleries in History Museum at the Castle during your trip to Appleton. While in this family-friendly area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6179014) ### Gardens of the Fox Cities Explore the great outdoors at Gardens of the Fox Cities, a lovely green space in Appleton. Attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6179092) ### Poplar Hall Learn about the events happening at Poplar Hall during your trip to Appleton. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=818567494439018496) ### Lawrence University 4.2/5 (141 reviews) Explore the campus of Lawrence University, during your travels in Appleton. While in this family-friendly area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6179004) ### Telulah Park After visiting Telulah Park, make a plan to see the other sights and activities in Appleton. While in this family-friendly area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6179070) ## Frequently asked questions ### What's the area like around Appleton Medical Center? ### What's the best place to stay near Appleton Medical Center? ### How many hotels can I expect to find close to Appleton Medical Center? ### If I need to cancel the hotel reservation for my stay near Appleton Medical Center, will I receive a refund? ### What can I see and do near Appleton Medical Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Apartments in Appleton ](https://www.expedia.ca/Appleton-Apartments.d6059808-aaApartments.Travel-Guide-Accommodation) - [B&B in Appleton ](https://www.expedia.ca/Appleton-Bed-And-Breakfast.d6059808-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Appleton ](https://www.expedia.ca/Appleton-Cabins.d6059808-aaCabins.Travel-Guide-Accommodation) - [Chalets in Appleton ](https://www.expedia.ca/Appleton-Chalets.d6059808-aaChalets.Travel-Guide-Accommodation) - 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