Title: Book The Best Hotels in Wykoff, MN for 2025 from CA $85 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Wykoff](https://expedia.ca/Wykoff-Vacation-Rentals.d3000443967.Travel-Guide-VacationRentals)[Wykoff Car Rentals](https://expedia.ca/Car-Rentals-In-Wykoff.d3000443967.Car-Rental-Guide)[Wykoff Vacation Packages](https://expedia.ca/Wykoff.d3000443967.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Wykoff, MN from CA $85 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Wykoff Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-12&d1=2025-10-12&endDate=2025-10-14&d2=2025-10-14&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-12&d1=2025-10-12&endDate=2025-10-14&d2=2025-10-14&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-12&d1=2025-10-12&endDate=2025-10-14&d2=2025-10-14&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-12&d1=2025-10-12&endDate=2025-10-14&d2=2025-10-14&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Wykoff%2C+Minnesota%2C+United+States+of+America®ionId=3000443967&latLong=43.707188%2C-92.268219&adults=2&startDate=2025-10-12&d1=2025-10-12&endDate=2025-10-14&d2=2025-10-14&amenities=PETS) ## Check prices for these dates Tonight [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2025-09-28&endDate=2025-09-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2025-09-29&endDate=2025-09-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3000443967&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 316 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Front of property](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/78958ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/a69b6a55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/w1712h1283x2y0-ed421a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/105000000/104020000/104013000/104012904/76c01c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Lodge inn Harmony 9.2/10 Wonderful (34) "Very friendly staff! Nice rooms that make you feel really comfortable." CA $173 CA $198 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Harmony-Hotels-Country-Lodge-Inn.h104012904.Hotel-Information) ![Indoor pool, open 7:00 AM to 11:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/f1672741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/7a5a17fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/a0dd0f28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/101000000/100370000/100366400/100366373/ce55c3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Trails Inn & Suites Preston 9.4/10 Exceptional (89) "Check-in was fast and staff was very courteous. The room was very clean and modern, Would definitely stay here again!" CA $176 CA $195 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Preston-Hotels-Country-Trails-Inn-Suites.h100366373.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/45535621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.2/10 Very good (1639) "Great location, beautiful hotel!" CA $186 CA $214 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3bd995bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1051) "Good place to stay " CA $102 CA $117 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/231bcb83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/fdcb0eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area Rochester 9.0/10 Wonderful (815) "All staff was friendly and the room and surroundings were clean." CA $90 CA $104 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/12906a03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/daff149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S Rochester 7.2/10 Good (1023) "Great location. Well priced. " CA $100 CA $115 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/b1805314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/bac0b2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/3613a59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG Kutzky Park 9.4/10 Exceptional (901) "Excellent and very clean property, beds were amazing " CA $166 CA $194 total includes taxes & fees Oct 11 - Oct 12 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/10494388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/8b35b717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/7b237c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Suites Rochester 9.0/10 Wonderful (656) "Staff were very friendly, property was nice and clean." CA $186 CA $237 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/b2634691.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/c713cda3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/c4eab347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room, 1 King Bed, Non Smoking, Microwave](https://images.trvl-media.com/lodging/115000000/114610000/114608500/114608460/3267fd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Green Gables Inn Lanesboro 9.4/10 Exceptional (46) "The stay was wonderful and will definitely return. " CA $148 CA $159 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Lanesboro-Hotels-Green-Gables-Inn.h114608460.Hotel-Information) ![Suite (Buffalo Bill Suite) | Living area](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/80518cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/1021cb95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/e0e6ae12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Buffalo Bill Suite)](https://images.trvl-media.com/lodging/2000000/1190000/1186500/1186426/8239cfbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stone Mill Hotel & Suites Lanesboro 9.2/10 Wonderful (644) "Beautiful and has lots of history " CA $146 CA $157 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Rochester-Hotels-Stone-Mill-Hotel-Suites.h1186426.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/05c87b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/6d4c49ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/81bc0968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3400000/3395700/3395689/5ef31f80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### America's Stay Inn Stewartville Stewartville 8.0/10 Very good (399) "Cleanliness of facility and room." CA $82 CA $89 total includes taxes & fees Oct 4 - Oct 5 [](https://www.expedia.ca/Rochester-Hotels-Americas-Stay-Inn-Stewartville.h3395689.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/fce6cfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South Rochester 9.4/10 Exceptional (175) "Check in was easy and staff was extremely helpful! We'll definitely stay here again. " CA $117 CA $135 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/42f521a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG Downtown Rochester 8.8/10 Excellent (833) "Very convenient to Mayo clinic and good restaurants. " CA $130 CA $149 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/569ab236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/28d8dcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic Rochester 8.4/10 Very good (1015) "A good place to stay." CA $112 CA $129 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/d3281bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/7b075080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/745c7377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Rochester Mayo Clinic Area South Rochester 9.6/10 Exceptional (221) "Great place" CA $171 CA $197 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/5f8bd693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/8cbdee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/84709368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/846600/846574/03c26c35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Rochester South Mayo Clinic Rochester 7.0/10 Good (75) "Nice hotel. Friendly staff and quiet. " CA $77 CA $89 total includes taxes & fees Oct 4 - Oct 5 [](https://www.expedia.ca/Rochester-Hotels-Extended-Stay-America-Suites-Rochester-South.h846574.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/dd4123a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/f6a03fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (Ground Floor)](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/46eaeea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Rochester Mayo Clinic Area Rochester 7.8/10 Good (1009) "Comfortable beds and good breakfast newspaper " CA $73 CA $85 total includes taxes & fees Oct 4 - Oct 5 [](https://www.expedia.ca/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/76e6edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/19467991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/5419eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/460000/459800/459763/1d0a97e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Rochester Mayo Clinic Area Rochester 7.2/10 Good (689) "Great place to stay close to places needed" CA $84 CA $97 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Rochester-Hotels-Baymont-By-Wyndham-Rochester-Mayo-Clinic-Area.h459763.Hotel-Information) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-014e984a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2555x4y4-921fa2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's Rochester 8.2/10 Very good (736) "staff was great no complaints room was phenomenal." CA $131 CA $151 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/bdf57892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/222c4dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/4db52fa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys Kutzky Park 8.4/10 Very good (891) "Good hotel in great location Needs updating Staff was very nice Pool and hot tub are nice Nice patio area Room was comfy Good stay for the price " CA $130 CA $149 total includes taxes & fees Oct 4 - Oct 5 [](https://www.expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-12&endDate=2025-10-13®ionId=3000443967&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FWykoff-Hotels.d3000443967.Travel-Guide-Hotels) ### Stay near popular Wykoff attractions [](https://expedia.ca/Eds-Museum-Hotels.0-l553248621532649595-0.Travel-Guide-Filter-Hotels) #### Ed's Museum You can spend time exploring the galleries in Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532649595) ## More cheap stays in Wykoff ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW, Rochester, MN CA $157 CA $180 total Sep 29 - Sep 30 includes taxes & fees 8.6/10 Excellent! (1,008 reviews) [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 1517 16th St Sw, Rochester, MN CA $131 CA $151 total Oct 2 - Oct 3 includes taxes & fees 8.2/10 Very Good! (730 reviews) [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Super 8 by Wyndham Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/30000/25200/25164/6da96ba9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Rochester Mayo Clinic Area 106 SE 21st Street, 21st Street And Broadway, Rochester, MN CA $73 CA $85 total Oct 4 - Oct 5 includes taxes & fees 7.6/10 Good! (1,006 reviews) [](https://expedia.ca/Rochester-Hotels-Super-8-By-Wyndham-Rochester-Mayo-Clinic-Area.h25164.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw, Rochester, MN CA $101 CA $116 total Oct 3 - Oct 4 includes taxes & fees 7.8/10 Good! (1,011 reviews) [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway, Rochester, MN CA $120 CA $138 total Oct 24 - Oct 25 includes taxes & fees 8.8/10 Excellent! (1,009 reviews) [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Rochester South - Mayo Area by IHG 4141 Maine Avenue SE, Rochester, MN CA $115 CA $132 total Oct 12 - Oct 13 includes taxes & fees 8.6/10 Excellent! (1,006 reviews) [](https://expedia.ca/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ## Hotels in Wykoff with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_w.jpg) 4 Star Hotels 2 properties [](https://expedia.ca/4Star-Wykoff-Hotels.s40-0-d3000443967.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_w.jpg) 3 Star Hotels 37 properties [](https://expedia.ca/3Star-Wykoff-Hotels.s30-0-d3000443967.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_w.jpg) 2 Star Hotels 28 properties [](https://expedia.ca/2Star-Wykoff-Hotels.s20-0-d3000443967.Travel-Guide-Filter-Hotels) ## Recent reviews of Wykoff hotels ![Spark by Hilton Rochester South](//images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 5/5 Excellent "Clean, comfortable & affordable " A verified traveller stayed at Spark by Hilton Rochester South Posted 18 hours ago [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 5/5 Excellent "Valet services, clean rooms, room service- everything was excellent. Made our stay with two little ones so easy" A verified traveller stayed at Kahler Grand Hotel Posted 3 days ago [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](//images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 5/5 Excellent "Staff was very friendly and helpful." A verified traveller stayed at SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys Posted 4 days ago [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Hampton Inn Rochester-South](//images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 5/5 Excellent "Clean rooms, great staff, nightly soup and a great breakfast" A verified traveller stayed at Hampton Inn Rochester-South Posted 4 days ago [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Country Inn & Suites Rochester South Mayo Clinic](//images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83_y.jpg) ### Country Inn & Suites Rochester South Mayo Clinic 5/5 Excellent "Older hotel but clean. Staff is great. Shuttle to clinic and hospital totally worth the stay. " A verified traveller stayed at Country Inn & Suites Rochester South Mayo Clinic Posted 4 days ago [](https://expedia.ca/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Residence Inn by Marriott Rochester Mayo Clinic Area South](//images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17_y.jpg) ### Residence Inn by Marriott Rochester Mayo Clinic Area South 5/5 Excellent "This hotel is very reasonably priced. The rooms were amazing and it’s located right across dining options. Felt very clean and safe. Enjoyed our stay here while it lasted. Definitely recommend it!" A verified traveller from Houston stayed at Residence Inn by Marriott Rochester Mayo Clinic Area South Posted 6 days ago [](https://expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Brentwood Inn & Suites](//images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 5/5 Excellent "Its right next to the Mayo, its a bit older, but its cozy!" A verified traveller stayed at Brentwood Inn & Suites Posted 6 days ago [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](//images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 5/5 Excellent "We have been up here numerous times for my appts at Mayo Clinic and we always stay at this hotel. Staff here are so helpful and friendly. I can’t say a single bad thing about this place or the staff. Highly recommend you won’t be disappointed. Clean, safe, quiet. I travel with my husband and we both enjoy this place. Definitely returning here. " A verified traveller stayed at Best Western Rochester Hotel Mayo Clinic Area/St. Mary's Posted 6 days ago [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 5/5 Excellent "Had appts at Mayo Clinic all week and was able to walk the underground subway to and from Mayo Clinic back to hotel room. The room was very clean and offered to clean room daily. Room had mini fridge and microwave. Ice machine down hall. Jimmy John’s right next door for easy food as we" A verified traveller stayed at Kahler Inn and Suites - Mayo Clinic Area Posted 8 days ago [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [4 Star Hotels in Stewartville](https://www.expedia.ca/4Star-Stewartville-Hotels.s40-0-d183438.Travel-Guide-Filter-Hotels) - [Hotels near Apache Mall](https://www.expedia.ca/Apache-Mall-Hotels.0-l6188936-0.Travel-Guide-Filter-Hotels) - [Canton Hotels](https://www.expedia.ca/Canton-Hotels.d3000443033.Travel-Guide-Hotels) - [Aparthotels in Chatfield](https://www.expedia.ca/Chatfield-Apart-Hotels.d183408-aaApartHotels.Travel-Guide-Accommodation) - [Cheap Hotels in Chatfield](https://www.expedia.ca/Chatfield-Hotels-Cheap-Hotels.0-0-d183408-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Chatfield](https://www.expedia.ca/Chatfield-Hotels-Luxury-Hotel.0-0-d183408-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAMgAQAAAADzCzvFAAAFHElEQVR4Xu3bQZLbOAxAUaZ64eUcQUfx0aSj6Sg+QpZedJljgCABsTWewlRlFvb/m1bDJJ92ipyk1P+hMg/+RCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJFZDvMrX00a9a93J5Ln6OtN8yvdZ7eW6/yfXaRrHVTwYpIPMykNbqJ4MUkHkZSGv1k98VWf03PdHdaxve2vaI2Mbfciuj41kgICAgEogGooGMbK12GcjaPtxlagu3Yo99Hd3khyE6Om6UQEBA5AcISAEBsV4jmm2/jFUjXaWBgBQQEAvEV2kgIOU/IFvRB3qt97G9lL/qw16xpS/5GGSR6VZA/GQQEBAQkL0N/g3xxlrbrq6euHXEVmm6agQCUkFA5g9AWiAgdUaOnSCvRlOrnwxyMppa/WSQk9HU6ieDnIymVj8Z5GQ0tfrJICejqdVPBjkZTa1+ckBOclffp2u9yTO+NkTfusfoVSAgJ4FMgYCcBDL1vog9qv3pXZ7v01Ue6KWdWMLT+y6/LXK1tW1XuW6Xr57xIG3bVa7bJQgISAsEpG27ynW7/ARkK/7ddTjxIReXNvoaJ2pjo/819HwrIN7YCDLWgvRAemMjyFgL0ntLRB/o1vPEUhaZ2va9jUpH+siKd2erQiAgIG0VyCLTeKJtjyMLBOSjEH2fHo9qP1FHx+27/DpW+UYQG4GAVBAQEJCfq6Qjslb9q2N7oC9tZPn2rbhryLF5BAICAgJizSMQED9xl9NkraZPb3XD9od8Ekd6d3Yrx7sDAQEBAZEfICBtofQTeYQvqh2x7SWcqK6cqOk/DBsb7VYsEBCQ9jEICEgF0QKi6XY9sdbbcMb2RX5sxV+xZfQdVsVbGYGAaCB9FYhtryAgIDWstXT7Gtx5dOwRNh4DAQHpgYBMn4CAKKL/SrqUy5huh1fsgRR7oNd6k+vZ1VUjEBAQEJARCEj9idjLs3xS4pvyLr/KiTrSE22kya30uztulEBAQCQQEJAKYgVEs+0XudYTZXu1E0tZ+qqerCrjGT9Wff/TM14DAQEBAbFAep+L2Af+qB5r+8hc6SGv2Md0VRF3DgQEpAcCMgUC8i0r9E3ZvrvWtrYzfp0t9Qd6WPWrH1THDVsgICB9FUgFAQGpM2JvylVOtGf8cGVxf+z7Kt8eVpX+JwELBASkBwICootB/NK37+UypluxB7qObnLCMXMN8buTkQXigYCAgIDIb7fD+dpHI7ZWPulr3bVjxyo/MWa3IqssEBAQEP0EBATECshJcftlTLf21q2jcSua3opttJEEAnISCAiIBAIST9SWNtdnvGYnSj7Sxp8ErFffcB9b2hzEAwEBkUBAtM9AVv9NT9T8vzIdXXug32S+tvkeltpIAgEBCSfuYamNJBAQkHDiHpbaSHpfxE68NORbrvV9+qqLO2Ld5WNbZf1wJRANBKQHAuLrQDSQl4hs15dnW1Xa3yZ/tS+963js21kjEBAQEBAQkCSiXXXxc6Tpqmu9t88UiV9626oRiI5AQAoICAiITfxSEc/WyvZ4oncNi7cwAgGxQHTkbWEEAmKB6MjbwuhzkGOLTOXlub9ih1Ed79M3WSp/ONBn/H28dYdAKshkgICAWCD145E/F0gqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSvQ/yN98HYOJ4TEacAAAAAElFTkSuQmCC)