10 Best Hotels in Serin, Lyon for 2026

A cityscape at dusk with a prominent cathedral and a bridge over a river.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Where to stay in Serin

Find the best Serin areas and neighborhoods for the activities you enjoy most. Learn more about Serin

A statue of a figure holding a staff, overlooking a city with red-roofed buildings and a river.

Lyon City Centre

Lyon City Centre is highly notable for its popular shops, and you might want to visit top sights like Bellecour Square and Place Carnot. See more of Lyon by jumping on the metro at Saint-André Tram Stop or Rue de l'Universite Tram Stop.

See properties

A statue of an angel overlooking a densely packed city with red-roofed buildings and a river.

Old Lyon

Explore the largest Renaissance district in Lyon, a UNESCO World Heritage site, featuring three sections: Saint Jean, Saint Paul, and Saint Georges. Discover museums, traboules, and historic churches, with Gare Saint-Paul as a transportation hub.

See properties

A red bridge over a river with a white statue of a man in a dynamic pose.

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

See properties

A cityscape at dusk with illuminated buildings, a river, and a prominent tower.

3rd Arrondissement

Discover the 3rd arrondissement's impressive towers, such as Tour Part-Dieu and Tour Oxygène, and enjoy cultural venues like Auditorium Maurice-Ravel and Théâtre de la Tête d'Or. Easily navigate with Metro Lines B and D, and Tramway T1 and T3.

See properties

A historic cathedral with intricate Gothic architecture, including a tall spire and a large rose window.

Les Cordeliers

Lyon’s architectural highlights are strewn across this meeting point of wealth, religion and gastronomy. Visit the bank headquarters and medieval church.

See properties

Top Serin Hotel Reviews

Kyriad Prestige Lyon Est - Saint Priest Eurexpo Hotel and Spa

10/10 Excellent

"Excellent ! Nous avons passé une nuit d’étape dans ce très bel hôtel pour prendre l’avion le lendemain, c’est devenu rare en France dans cette gamme. Tout est au rdv pour être qualifié excellent : confort, propreté, calme, accueil, prestations. Je recommande fortement ! Rien à redire ! Il faut être véhiculé pour y venir. (Un seul bémol c’est la moquette qui fait éternuer les personnes soumises aux allergies)"

Boscolo Lyon Hôtel & Spa

8/10 Good

"We Only need coffee and a croissant for breakfast When we told the restaurant hostess she told as we couldn’t sit in the breakfast room but only in the non air conditioned empty salon We were made to feel like 2nd class citizens We declined her offer and had our breakfast in a cool reception area Hotel Perfectly placed"

The Ruck Hotel

10/10 Excellent

"This is a very cool hotel!! We absolutely loved our family room which consisted of two interconnected rooms! The decor and layout was perfect and we slept very well!! We also appreciated them accomodating our large and tall car in the front car park. Only negatives were that the restaurant was closed so no food onsite but the lovely guy on reception booked us a table at Chez Carlo (a pizza place nearby). The pool is also in a building next door and has lots of rules about costumes men wear and everyone has to wear hats so we decided to leave as it was very restrictive! Points to note: The hotel is AMAZING!! Just wish we could have stayed in and had dinner in the restuarant as the area was a little sketchy and we were approached several times by people begging."

Hôtel Mercure Lyon Centre - Gare Part Dieu

10/10 Excellent

"We loved how this place was at the centre of the hub of Lyon and everything is very accessible by it’s proximity to train stations, buses and trans right in front of the Hotel, main shopping centre, Westfield and La Fayette mall. The place is very clean, comfortable beds, the staffs were very friendly, easy to ask favors from, Service oriented. The proximity to food stores and restaurants are also very close which make it a very convenient place to stay whilst in Lyon, Overall we highly recommend this place especially if you are on a budget."

Frequently asked questions

When is the best time to go to Serin?

The best time to visit Serin is during the warmer months, from May to September, when the weather is most pleasant for outdoor activities and exploring the region.

May and June offer mild temperatures, generally ranging from 15°C to 22°C, and the countryside is lush and green. This period is ideal for those who enjoy hiking or cycling through the scenic Auvergne landscapes without the peak summer heat. You'll find fewer crowds compared to July and August, allowing for a more relaxed experience.

July and August are the warmest months, with temperatures often between 20°C and 28°C. This is superb for enjoying the local lakes and rivers, or for simply relaxing outdoors. Many local festivals and markets take place during these months, offering a chance to experience the regional culture. Families often find this time particularly good due to the warm weather and the array of outdoor pursuits available.

September is also a lovely time, with comfortable temperatures similar to May and June, and the beginning of the autumn colours. The grape harvest often begins around this time, and the local cuisine is at its best with fresh produce.

Can I cancel my hotel reservation on Expedia?

Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Serin hotel for you.

How much is the nightly rate at a Serin hotel?

Hotel prices in Serin often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia

More ways to book

Book Hotels in Serin on Expedia.fr

Hotels in Serin, Lyon

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Serin hotels

1. Hôtel Lyon Métropole & Spa

2. Fourvière Hôtel Lyon

3. Le Phenix Hotel

4. The People Lyon

5. Académie Hôtel Lyon

6. Grand Hotel Des Terreaux

7. Hotel Saint Vincent

8. Maison Nô

9. Residence Belambra Villemanzy

10. Hôtel des Célestins

11. Campanile PRIME - Lyon Centre Gare Part Dieu

12. Collège Hôtel

13. Hôtel des Artistes

14. Hôtel de Paris

15. Hotel du Theatre

16. Citadines Presqu'île Lyon

17. Hotel Silky by HappyCulture

18. Hôtel La Résidence Lyon

19. Globe et Cecil Hôtel

20. Best Western Hotel Saint Antoine

Where to stay in Serin

Lyon City Centre

Old Lyon

Bellecour - Hôtel Dieu

3rd Arrondissement

Les Cordeliers

Top Serin Hotel Reviews

Kyriad Prestige Lyon Est - Saint Priest Eurexpo Hotel and Spa

Frequently asked questions

Explore a world of travel with Expedia