
Search Santee Villa Rentals from CA $76
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
In two weeks
In two months
In three months
In four months
Our top choices for Santee villas

1. Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (1,011 reviews)
The price is CA $144
CA $160 total
includes taxes & fees
Nov 29 - Nov 30

2. Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,000 reviews)
The price is CA $172
CA $191 total
includes taxes & fees
Nov 25 - Nov 26

3. Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,511 reviews)
The price is CA $112
CA $124 total
includes taxes & fees
Nov 8 - Nov 9

4. Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,002 reviews)
The price is CA $194
CA $215 total
includes taxes & fees
Nov 15 - Nov 16

5. Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,000 reviews)
The price is CA $165
CA $183 total
includes taxes & fees
Nov 15 - Nov 16

6. Holiday Inn Santee by IHG
Holiday Inn Santee by IHGSantee
8.2 out of 10, Very good, (1,000 reviews)
The price is CA $161
CA $178 total
includes taxes & fees
Nov 15 - Nov 16

7. Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
8.0 out of 10, Very good, (1,000 reviews)
The price is CA $139
CA $155 total
includes taxes & fees
Nov 29 - Nov 30

8. Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
7.2 out of 10, Good, (787 reviews)
The price is CA $90
CA $100 total
includes taxes & fees
Nov 16 - Nov 17

9. Super 8 by Wyndham Santee/I-95
Super 8 by Wyndham Santee/I-95Santee
6.8 out of 10, (477 reviews)
The price is CA $89
CA $99 total
includes taxes & fees
Nov 15 - Nov 16

10. Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
5.8 out of 10, (615 reviews)
The price is CA $76
CA $91 total
includes taxes & fees
Nov 29 - Nov 30

11. Red Roof Inn Santee
Red Roof Inn SanteeSantee
6.6 out of 10, (668 reviews)
The price is CA $88
CA $98 total
includes taxes & fees
Nov 11 - Nov 12

12. Econo Lodge Santee
Econo Lodge SanteeSantee
6.4 out of 10, (317 reviews)
The price is CA $88
CA $98 total
includes taxes & fees
Dec 7 - Dec 8

13. Ashburn Inn Manning I 95
Ashburn Inn Manning I 95Manning
The price is CA $85
CA $94 total
includes taxes & fees
Nov 10 - Nov 11

14. Bells Marina & Resort
Bells Marina & ResortEutawville
8.6 out of 10, Excellent, (103 reviews)
The price is CA $103
CA $118 total
includes taxes & fees
Nov 8 - Nov 9

15. Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
The price is CA $153
CA $170 total
includes taxes & fees
Nov 22 - Nov 23

16. Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
8.4 out of 10, Very good, (850 reviews)
The price is CA $135
CA $150 total
includes taxes & fees
Nov 29 - Nov 30

17. Peach Tree Inn
Peach Tree InnSt. George
7.0 out of 10, Good, (270 reviews)
The price is CA $86
CA $92 total
includes taxes & fees
Nov 16 - Nov 17

18. SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western ManningManning
8.6 out of 10, Excellent, (1,003 reviews)
The price is CA $114
CA $127 total
includes taxes & fees
Nov 22 - Nov 23

19. Hampton Inn & Suites Orangeburg
Hampton Inn & Suites OrangeburgOrangeburg
9.4 out of 10, Exceptional, (862 reviews)
The price is CA $177
CA $196 total
includes taxes & fees
Nov 25 - Nov 26

20. Sunset Inn Manning I 95
Sunset Inn Manning I 95Summerton
5.2 out of 10, (65 reviews)
The price is CA $62
CA $76 total
includes taxes & fees
Dec 6 - Dec 7
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find vacation rentals that suit your style
Cabins
Private vacation homes
Save an average of 15% on thousands of hotels when you're signed in
Top Santee Hotel Reviews

SureStay Hotel by Best Western Manning
8/10 Good
Find out more about Santee
Santee Villas information
Number of reviews | 5,491 |
|---|---|
Accommodation | 0 Villas |
Lowest Price | CA $76 |
Highest Price | CA $215 |
Frequently asked questions
Explore a world of travel with Expedia
- Hampton Inn Manning
- Bowman Hotels
- B&B in Coastal South Carolina
- Lodges in Livingston
- Pet-Friendly Hotels in Orangeburg
- Motels in Summerville
- Cabin Rentals in St. Stephen
- Condo Rentals in Santee
- Santee Hotels
- Pet-Friendly Hotels in Manning
- Condo Rentals in South Carolina
- B&B in Wedgewood
- Hampton Inn Santee
- Holiday Inn Santee by IHG
- Fairfield Inn & Suites by Marriott Santee
- Cabin Rentals in Manning
- Wyndham Vacation Resorts Lake Marion
- Red Roof Inn Hotels in Orangeburg
- B&B in Manning
- Eastover Hotels
- Palmetto Inn
- Condo Rentals in Pinewood
- Cheap Hotels in Orangeburg
- Boat House (private Cabin)
- Hotels near Lake Marion
- Golf Hotels in Santee
- Ramada by Wyndham Santee I
- Hotels with an Indoor Pool in Orangeburg
- Resorts in Knightsville
- Sumter Hotels
- B&B in Summerville
- Condo Rentals in Providence
- Best Western Hotels in St. Stephen
- Cabin Rentals in South Carolina
- Guest Houses in Cedar Creek
- Apartments in Wedgewood
- Apartments in Cameron
- Surestay Hotel by Best Western Manning
- Lakefront Cottage on Lake Marion
- Orangeburg Hotels
- Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
- Motels in Ridgeville
- Spark by Hilton Orangeburg
- Apartments in Wilkinson Heights
- Cottages in Brookdale
- All Inclusive Resorts and in South Carolina
- Cabin Rentals in Bowman
- Best Western Hotels in St. George
- Luxury Hotels in Santee
- Cottages in Cameron
- Saint Matthews Hotels
- Cottages in Cordova
- Cottages in Coastal South Carolina
- Manning Hotels
- Branchville Hotels
- Eutawville Hotels
- Guest Houses in Saint Matthews
- Summerton Hotels
- Ridgeville Hotels
- Pineville Hotels
- Motels in Lynchburg
- Best Western Hotels in Orangeburg
- Red Roof Inn Hotels in Bowman
- 5 Star Hotels in Manning
- Apartments in Shiloh
- Baymont by Wyndham Santee
- Hotels with a Pool in Manning
- Cabin Rentals in Jamison
- Apartments in Brookdale
- Charleston Hotels
- B&B in Mulberry
- Hotels with Free Breakfast in Brookdale
- St. George Hotels
- Red Roof Inn St George
- Flights to Orangeburg
- Flights from Vancouver (YVR) to Columbia (CAE)
- Flights to Santee
- Flights to South Carolina
- Flights to Charleston
- Flights from Toronto (YYZ) to Columbia (CAE)
- Flights from Toronto (YYZ) to Charleston (CHS)
- Flights to Sumter
- Flights from Vance
- Flights from Buffalo (BUF) to Charleston (CHS)
- Flights from Vancouver (YVR) to Charleston (CHS)



































































