
Santa Cruz Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santa Cruz Vacation
An easy way to experience this unique city is with a custom-made Santa Cruz vacation package. Base yourself in the neighborhood of La Candelaria, which is good for dining, history and shopping or go someplace else — our packages are all about you. Every trip to Santa Cruz needs a well-thought-out itinerary. Fill yours with major attractions such as Atanasio Giradot Stadium, Botero Plaza and Lights Park. A couple of quick clicks is all it takes to build your dream Santa Cruz vacation on Expedia.
Top Santa Cruz Vacation Deals
Price found within the past 48 hours. Click for updated prices.




Medellin Marriott Hotel
El Poblado
CA $1,606
per person
Nov 27 - Dec 4
found 1 day ago
Roundtrip non-stop flight included
Montreal (YMQ) to Medellín (MDE)
9/10 Wonderful! (647 reviews)
Truly exceptional service, from the front desk all the way up to the cleaning staff. Everyone employee we came in contact with was kind, attentive, courteous and very very receptive to our particular needs. I definitely recommend this Marriott.
Reviewed on Oct 12, 2026
Ready to book your vacation to Santa Cruz?
Santa Cruz Hotel Deals

Hashtag 98 Hotel By Jalo
Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
CA $98
CA $98 total
Nov 2 - Nov 3
9.2/10 Wonderful! (2,306 reviews)
"I always have a fantastic stay at this hotel! The staff is super friendly and welcoming every single time. The rooms are consistently clean and offer amazing views of El Poblado. I really appreciate the wide variety of breakfast options each morning, and the bed is exceptionally comfortable. The ..."
Reviewed on Oct 15, 2026

Calle Flora Hotel by Jalo
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
CA $117
CA $117 total
Oct 29 - Oct 30

Heiss Hotel By Jalo
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
CA $98
CA $98 total
Oct 18 - Oct 19
9.2/10 Wonderful! (2,000 reviews)
"Nice and friendly staff. Located in an ideal community. Close to convenience store and many great restaurants."
Reviewed on Oct 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa Cruz

Medellin: Comuna 13 Graffiti Tour, Cable Car & Street Food
CA $28
per adult
86% of travellers recommend

Medellín: Comuna 13 District Tour with Cable Car Ride
CA $38
per adult
98% of travellers recommend
Frequently asked questions
How much does a Santa Cruz vacation package cost?
You'll find cheap prices from CA $970 on Expedia for your Santa Cruz escape. However, a range of factors like the season, length of stay and your choice of hotel will determine how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
Travel in the low or shoulder season and you're likely to find cheap Santa Cruz vacation packages. Remember that school vacation periods and major festivals and events can have an impact on prices, so do some research before booking.
How many days is enough for Santa Cruz?
With about 4 days, you'll have enough time to enjoy popular neighbourhoods like Provenza and Zona Rosa during your Santa Cruz vacation. Remember to also add Medellin Botanical Garden and Unicentro Shopping Centre to your must-do list. In the mood for more adventures? Consider exploring outside of Santa Cruz on tours and day trips.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some unbeatable Santa Cruz package deals. When you begin your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Santa Cruz package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging flights and hotels separately. Better still, you can tailor your Santa Cruz trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Santa Cruz?
Secure incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Santa Cruz vacation.
How to plan a trip to Santa Cruz?
- Pick your dates: The things you'd like to do in Santa Cruz and your preferred season can help you decide when to get away.
- Plan your budget wisely: In addition to the price of your hotel, you should consider other expenses too. These include food, flights and transportation. Also, set aside a little extra for unexpected expenses that may come up during your trip to Santa Cruz.
- Decide how long to go away for: Now that you're up to speed on Santa Cruz, you can work out the ideal length of your vacation. Create a rough itinerary and give yourself enough time for all the things you want to do.
- Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a personalized Santa Cruz vacation package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.








