Santa Cruz Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*
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Your Santa Cruz Vacation

An easy way to experience this unique city is with a custom-made Santa Cruz vacation package. Base yourself in the neighborhood of La Candelaria, which is good for dining, history and shopping or go someplace else — our packages are all about you. Every trip to Santa Cruz needs a well-thought-out itinerary. Fill yours with major attractions such as Atanasio Giradot Stadium, Botero Plaza and Lights Park. A couple of quick clicks is all it takes to build your dream Santa Cruz vacation on Expedia.

Top Santa Cruz Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Aparta Suites Torre Poblado

Aparta Suites Torre Poblado

El Poblado
CA $990
per person
Nov 24 - Nov 29
found 19 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Medellín (MDE)
8.8/10 Excellent! (936 reviews)
N/a

Reviewed on Oct 14, 2026

Devú

Devú

El Poblado
CA $1,571
per person
Nov 27 - Dec 4
found 24 hours ago
Roundtrip non-stop flight included
Montreal (YMQ) to Medellín (MDE)
9.8/10 Exceptional! (40 reviews)
Medellin Marriott Hotel

Medellin Marriott Hotel

El Poblado
CA $1,606
per person
Nov 27 - Dec 4
found 24 hours ago
Roundtrip non-stop flight included
Montreal (YMQ) to Medellín (MDE)
9/10 Wonderful! (647 reviews)
Truly exceptional service, from the front desk all the way up to the cleaning staff. Everyone employee we came in contact with was kind, attentive, courteous and very very receptive to our particular needs. I definitely recommend this Marriott.

Reviewed on Oct 12, 2026

Living by Armoniko

Living by Armoniko

Laureles
CA $1,219
per person
Nov 19 - Nov 26
found 17 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Medellín (MDE)
9.4/10 Exceptional! (83 reviews)
Revellion by EP

Revellion by EP

El Poblado
Save 100% on your flight
CA $2,703
per person
Jan 1 - Jan 7
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to Medellín (MDE)
9/10 Wonderful! (7 reviews)
In the heart of all parque Lleras and provenza!

Reviewed on Sep 8, 2026

Ready to book your vacation to Santa Cruz?

Choose your dates

Santa Cruz Hotel Deals

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
CA $98
CA $98 total
Nov 2 - Nov 3
9.2/10 Wonderful! (2,305 reviews)
"The Hotel is not for the light sleepers, the city is loud. I had a wonderful time here and all the staff were very helpful and welcoming. The hotel is in a safer area. The rustic modern look is great. I would definitely be back. Great spot for visiting a lot of things to do at walking distance."

Reviewed on Oct 14, 2026

Hashtag 98 Hotel By Jalo
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
CA $133
CA $133 total
Oct 18 - Oct 19
9/10 Wonderful! (1,513 reviews)
"I loved the breakfast buffet they offered each morning"

Reviewed on Oct 14, 2026

Calle Flora Hotel by Jalo
Heiss Hotel By Jalo

Heiss Hotel By Jalo

1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
CA $107
CA $107 total
Nov 4 - Nov 5
9.2/10 Wonderful! (1,998 reviews)
"The place was clean, Breakfast was good but the room were small and they were working on building and roads nearby so it was noisy during sleeping hours."

Reviewed on Oct 15, 2026

Heiss Hotel By Jalo
See all 4,651 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santa Cruz

Medellin: Comuna 13 History & Graffiti Tour with Cable Car

Medellin: Comuna 13 Graffiti Tour, Cable Car & Street Food

CA $28
per adult
86% of travellers recommend
Medellin: Comuna 13 Graffiti Tour, Cable Car & Street Food
Medellín: Comuna 13 District Tour with Cable Car Ride

Medellín: Comuna 13 District Tour with Cable Car Ride

CA $38
per adult
98% of travellers recommend
Medellín: Comuna 13 District Tour with Cable Car Ride
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You'll find cheap prices from CA $990 on Expedia for your Santa Cruz escape. However, a range of factors like the season, length of stay and your choice of hotel will determine how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
Travel in the low or shoulder season and you're likely to find cheap Santa Cruz vacation packages. Remember that school vacation periods and major festivals and events can have an impact on prices, so do some research before booking.
How many days is enough for Santa Cruz?
With about 4 days, you'll have enough time to enjoy popular neighbourhoods like Provenza and Zona Rosa during your Santa Cruz vacation. Remember to also add Medellin Botanical Garden and Unicentro Shopping Centre to your must-do list. In the mood for more adventures? Consider exploring outside of Santa Cruz on tours and day trips.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some unbeatable Santa Cruz package deals. When you begin your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Santa Cruz package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging flights and hotels separately. Better still, you can tailor your Santa Cruz trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Santa Cruz?
Secure incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Santa Cruz vacation.
How to plan a trip to Santa Cruz?
  1. Pick your dates: The things you'd like to do in Santa Cruz and your preferred season can help you decide when to get away.
  2. Plan your budget wisely: In addition to the price of your hotel, you should consider other expenses too. These include food, flights and transportation. Also, set aside a little extra for unexpected expenses that may come up during your trip to Santa Cruz.
  3. Decide how long to go away for: Now that you're up to speed on Santa Cruz, you can work out the ideal length of your vacation. Create a rough itinerary and give yourself enough time for all the things you want to do.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a personalized Santa Cruz vacation package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.