Santa Cruz Vacation Packages

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Your Santa Cruz Vacation

An easy way to experience this unique city is with a custom-made Santa Cruz vacation package. Base yourself in the neighborhood of La Candelaria, which is good for dining, history and shopping or go someplace else — our packages are all about you. Every trip to Santa Cruz needs a well-thought-out itinerary. Fill yours with major attractions such as Atanasio Giradot Stadium, Botero Plaza and Lights Park. A couple of quick clicks is all it takes to build your dream Santa Cruz vacation on Expedia.

Top Santa Cruz Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Örök Landscape Hotel

Örök Landscape Hotel

3.5 out of 5
Price was CA $1,625, price is now CA $1,053 per person
CA $1,053
per person
Sep 25 - Oct 1
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Medellín (MDE)
9/10 Wonderful! (8 reviews)
Staying at this hotel was the highlight of our visit to Colombia. It is more of a retreat than a hotel. We only booked a single night here because we wanted to spend a day in the Medellin area and close to the airport, but after the first night we cancelled our flights and decided to stay and enjoy this property and their hospitality for an extra 2 days!

Reviewed on Jul 17, 2026

Elcielo Hotel & Restaurant

Elcielo Hotel & Restaurant

4 out of 5
El Poblado
Price was CA $2,858, price is now CA $1,795 per person
CA $1,795
per person
Sep 19 - Sep 25
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Medellín (MDE)
9.6/10 Exceptional! (261 reviews)
Me gustó mucho solo que las abitaciones estaban un poco chiquitas y no tiene parqueo

Reviewed on Jun 27, 2026

Hotel Los Recuerdos

Hotel Los Recuerdos

3.5 out of 5
Price was CA $1,782, price is now CA $1,212 per person
CA $1,212
per person
Oct 5 - Oct 12
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Medellín (MDE)
8.2/10 Very good! (658 reviews)
A mi ver la limpieza sobre todo en los sillones me parecio mala como el televisor que falla mucho,, pero el personal exelente , y las instalaciones muy bien y la ubicacion ideal

Reviewed on Jul 12, 2026

Golden Valley Hotel

Golden Valley Hotel

3.5 out of 5
El Poblado
Price was CA $1,989, price is now CA $1,383 per person
CA $1,383
per person
Sep 1 - Sep 8
found 1 day ago
Roundtrip flight included
Edmonton (YEA) to Medellín (MDE)
9.2/10 Wonderful! (134 reviews)
Felt like at home, rooms are ver clean , staff is very helpful, and the top floor is very nice.

Reviewed on Jun 26, 2026

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

4 out of 5
El Poblado
Price was CA $2,266, price is now CA $1,578 per person
CA $1,578
per person
Sep 1 - Sep 8
found 1 day ago
Roundtrip flight included
Edmonton (YEA) to Medellín (MDE)
9/10 Wonderful! (1,128 reviews)

Ready to book your vacation to Santa Cruz?

 

Choose your dates

Santa Cruz Hotel Deals

Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is CA $96 per night from Jul 21 to Jul 22
CA $96
CA $96 total
Jul 21 - Jul 22
Heiss Hotel By Jalo
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

4.5 out of 5
Carrera 43a No.7-50, Avenida El Poblado Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Aug 17 to Aug 18
CA $125
CA $125 total
Aug 17 - Aug 18
Dann Carlton Medellin Hotel
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

4 out of 5
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
The price is CA $116 per night from Jul 21 to Jul 22
CA $116
CA $116 total
Jul 21 - Jul 22
Calle Flora Hotel by Jalo
See all 4,570 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
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Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

What to do in Santa Cruz

Medellín: Comuna 13 District Tour with Cable Car Ride

Medellín: Comuna 13 District Tour with Cable Car Ride

CA $31
per adult
96% of travellers recommend
Medellín: Comuna 13 District Tour with Cable Car Ride
Day tour to Guatapé +Rock del Peñol: Breakfast, Lunch and Boat.

Guatapé,la Piedra,crucero con vista a casa de famos &comidas

CA $55
per adult
98% of travellers recommend
Guatapé,la Piedra,crucero con vista a casa de famos &comidas
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You'll find cheap prices from CA $1,053 on Expedia for your Santa Cruz escape. However, a range of factors like the season, length of stay and your choice of hotel will determine how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
Travel in the low or shoulder season and you're likely to find cheap Santa Cruz vacation packages. Remember that school vacation periods and major festivals and events can have an impact on prices, so do some research before booking.
How many days is enough for Santa Cruz?
With about 4 days, you'll have enough time to enjoy popular neighbourhoods like Provenza and Zona Rosa during your Santa Cruz vacation. Remember to also add Medellin Botanical Garden and Unicentro Shopping Centre to your must-do list. In the mood for more adventures? Consider exploring outside of Santa Cruz on tours and day trips.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some unbeatable Santa Cruz package deals. When you begin your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Santa Cruz package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging flights and hotels separately. Better still, you can tailor your Santa Cruz trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Santa Cruz?
Secure incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Santa Cruz vacation.
How to plan a trip to Santa Cruz?

  1. Pick your dates: The things you'd like to do in Santa Cruz and your preferred season can help you decide when to get away.
  2. Plan your budget wisely: In addition to the price of your hotel, you should consider other expenses too. These include food, flights and transportation. Also, set aside a little extra for unexpected expenses that may come up during your trip to Santa Cruz.
  3. Decide how long to go away for: Now that you're up to speed on Santa Cruz, you can work out the ideal length of your vacation. Create a rough itinerary and give yourself enough time for all the things you want to do.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a personalized Santa Cruz vacation package.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.