Title: Santa Cruz Island Vacation Home Rentals : Search Top Private Vacation Homes for Rent | Expedia.ca [Santa Cruz Island Travel Guide](https://expedia.ca/Santa-Cruz-Island.dx6053670)[Hotels in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz Island](https://expedia.ca/Santa-Cruz-Island-Vacation-Rentals.d6053670.Travel-Guide-VacationRentals)[Flights to Santa Cruz Island](https://expedia.ca/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights)[Things to do in Santa Cruz Island](https://expedia.ca/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)[Santa Cruz Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz-Island.d6053670.Car-Rental-Guide)[Santa Cruz Island Vacation Packages](https://expedia.ca/Santa-Cruz-Island.d6053670.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/04d5e478ee175ffd174b1e23d51916f4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Santa Cruz Island Vacation Rentals ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-10&endDate=2025-10-12&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6053670&startDate=2025-11-28&endDate=2025-11-30&adults=2&lodging=VACATION_HOME&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Santa Cruz Island Vacation Homes ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105890000/105888700/105888699/7292040b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/106000000/105890000/105888700/105888699/7071e7cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/106000000/105890000/105888700/105888699/3bdd51b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105890000/105888700/105888699/8c94f367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Odessa - Galapagos Minisuite 500 ft From THE Ocean #2 Puerto Ayora CA $44 CA $78 total Oct 6 - Oct 7 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Odessa-Galapagos-Minisuite-500-Ft-From-THE-Ocean-2.h105888699.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/0ddba558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/89bc8614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/c4bc6b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/ea4f48dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos Puerto Ayora CA $156 CA $184 total Oct 11 - Oct 12 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information) ![Microwave, oven](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/6cb34f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/910a26ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/4e0bcac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100650000/100640300/100640217/6785ebb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jardin de Galápagos. Galápagos Islands CA $94 CA $168 total Oct 7 - Oct 8 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Jardin-De-Galapagos.h100640217.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/369f220c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome, 1 Bedroom, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/c9a6e134.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2ad1a614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome, 1 Bedroom, Non Smoking, City View](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2847ed9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Galapagos Puerto Ayora 6.0/10 (1) "着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。" CA $126 CA $147 total Oct 6 - Oct 7 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/a362da8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, in-room safe, travel crib, WiFi](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/a746834d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/18eed3a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37760000/37756500/37756447/9c7526d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Life Two Bedroom Galapagos Casita Puerto Ayora 10/10 Exceptional (3) "We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!" CA $180 CA $229 total Oct 6 - Oct 7 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Island-Life-Two-Bedroom-Galapagos-Casita.h37756447.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/46b3f49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/b574e039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/d7cc9d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Two Bedroom house - The Galapagos Pearl Hotel Puerto Ayora 10/10 Exceptional (1) "We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us... CA $279 CA $353 total Oct 6 - Oct 7 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/863e8c72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, cookware/dishes/utensils, spices, dining tables](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/592985cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/3ca1da7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/47d8324c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dominga Terrace Unknown CA $50 CA $148 total Oct 6 - Oct 7 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Vrbo-Property.h116005423.Hotel-Information) ![3 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/a02678e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/f77924fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/d0327e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, toilet paper](https://images.trvl-media.com/lodging/91000000/90230000/90226500/90226451/3e0e5f4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aventura y Confort en Galápagos – Suite Familiar Puerto Ayora 8.0/10 Very good (1) "Large property - 3 bed rooms and 3-1/2 bathrooms. It was an excellent value. The home had fantastic air conditioning - which we really appreciated after a long day of excursions. There was plenty of filtered water and the washing machine was a bonus. In terms of negatives: - No WiFi (but the host was clear about this from the beginning) - No mirrors over sinks (had to use our phone’s camera to shave) - Dogs barking at night - No hot water in the morning - No address - difficult to explain... CA $112 CA $188 total Oct 11 - Oct 12 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Galapagos-HOLIDAY-SUITE-3-Bedrooms-6-Guests-EAST-SIDE.h90226451.Hotel-Information) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105890000/105888300/105888282/afa05d4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105890000/105888300/105888282/6f2c1ee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/106000000/105890000/105888300/105888282/9ec3912b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/106000000/105890000/105888300/105888282/e7a5a529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Odessa - Galapagos Minisuite 500 ft From THE Ocean #1 Puerto Ayora CA $44 CA $78 total Oct 6 - Oct 7 [](https://www.expedia.ca/Puerto-Ayora-Hotels-Odessa-Galapagos-Minisuite-500-Ft-From-THE-Ocean-1.h105888282.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=6053670&adults=2&lodging=VACATION_HOME&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Island-Private-Vacation-Homes.d6053670-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Island-Private-Vacation-Homes.d6053670-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Santa Cruz Island Hotel Reviews ![Plaza Luna Suites](//images.trvl-media.com/lodging/95000000/94780000/94770600/94770586/9bbdcdca_y.jpg) ### Plaza Luna Suites 10/10 Excellent "Very friendly and helpful front desk. Good breakfast, fresh eggs made to order. Nice big rooms." [](https://expedia.ca/Puerto-Ayora-Hotels-Plaza-Luna-Suites.h94770586.Hotel-Information) ![Hotel La Casa de Judy](//images.trvl-media.com/lodging/15000000/14660000/14658100/14658017/436a78c2_y.jpg) ### Hotel La Casa de Judy 10/10 Excellent "Clean and comfortable room. Good breakfast. Nice roof top view of ocean." [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-La-Casa-De-Judy.h14658017.Hotel-Information) ![Hotel Cucuve](//images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/733c9cb5_y.jpg) ### Hotel Cucuve 10/10 Excellent "Wonderful staff, beautiful room, delicious breakfast!" [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ![Hotel Ninfa](//images.trvl-media.com/lodging/11000000/10090000/10087200/10087137/08eca00e_y.jpg) ### Hotel Ninfa 10/10 Excellent "Great" [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Ninfa.h10087137.Hotel-Information) ![Hotel Fiesta](//images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f_y.jpg) ### Hotel Fiesta 10/10 Excellent "The rooms were very comfortable, the jacuzzi was a very nice surprise for us, the weather was a bit cold so we had a very good time there. It has a very convenient location you can walk to many places. The breakfast was very good and the staff was very kind. " [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information) ![El Barranco Galapagos](//images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/910f927d_y.jpg) ### El Barranco Galapagos 10/10 Excellent "Staff was great. Pool was really nice with lots of wildlife to watch right off the side of the it." [](https://expedia.ca/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information) ![Royal Palm Galapagos, Curio Collection Hotel by Hilton](//images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/215f955b_y.jpg) ### Royal Palm Galapagos, Curio Collection Hotel by Hilton 10/10 Excellent "The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again." [](https://expedia.ca/Santa-Rosa-Hotels-The-Royal-Palm-Hotel.h12535025.Hotel-Information) ![Ikala Galapagos Hotel](//images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed_y.jpg) ### Ikala Galapagos Hotel 10/10 Excellent "Centrally located with lots of choices to shop and eat. A block away from The Port and plenty of taxis available. The Staff was great and their breakfasts in the morning are incredible! WiFi was a little spotty but that’s the only thing I’d change. They even packed us little snack bags for our airport run!! " [](https://expedia.ca/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Fernandina Hotel & Spa Galápagos](//images.trvl-media.com/lodging/91000000/90030000/90029600/90029511/27a5429e_y.jpg) ### Fernandina Hotel & Spa Galápagos 10/10 Excellent "Fernandina was a delightful property with everything I needed for a final night on the island. It was close to food and shopping and the room was excellent, large and comfy with a nice shower and bathroom. Not to mention the adorable kitten sitting outside my doorway. Gracias " [](https://expedia.ca/Puerto-Ayora-Hotels-HOTEL-FERNANDINA.h90029511.Hotel-Information) ## Find out more about Santa Cruz Island ## Santa Cruz Island Vacation Homes information | Number of reviews | | | --- | --- | | Accommodation | Vacation Homes | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [5 Star Hotels in Santa Fe Island](https://www.expedia.ca/5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) - [Baltra Hotels](https://www.expedia.ca/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Aparthotels in Bartolome Island](https://www.expedia.ca/Bartolome-Island-Apart-Hotels.d6336382-aaApartHotels.Travel-Guide-Accommodation) - [Lgbt Friendly Hotels in Bellavista](https://www.expedia.ca/Bellavista-Hotels-LGBT-Friendly-Hotel.0-0-d6342722-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Bellavista Hotels](https://www.expedia.ca/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - 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[Car rentals near Galápagos](https://www.expedia.ca/Destinations-In-Galapagos.d1371.Car-Rental-Destinations) - [Enterprise Rental Cars in Santa Fe Island](https://www.expedia.ca/Enterprise-Car-Rentals-In-Santa-Fe-Island.d6336630-c15.Car-Rental-Guide-Suppliers) - [Flizzr Rental Cars in North Seymour Island](https://www.expedia.ca/Flizzr-Car-Rentals-In-North-Seymour-Island.d6336659-c1098.Car-Rental-Guide-Suppliers) - [Get Your Car Rental Cars in Santa Fe Island](https://www.expedia.ca/Get-Your-Car-Car-Rentals-In-Santa-Fe-Island.d6336630-c1120.Car-Rental-Guide-Suppliers) - [Global Rent a Car Rental Cars in Santa Fe Island](https://www.expedia.ca/Global-Rent-A-Car-Car-Rentals-In-Santa-Fe-Island.d6336630-c1062.Car-Rental-Guide-Suppliers) - [Goldcar rental Rental Cars in Santa Fe Island](https://www.expedia.ca/Goldcar-Rental-Car-Rentals-In-Santa-Fe-Island.d6336630-c1022.Car-Rental-Guide-Suppliers) - [Guerin Rental Cars in Daphne Islands](https://www.expedia.ca/Guerin-Car-Rentals-In-Daphne-Islands.d6336492-c1129.Car-Rental-Guide-Suppliers) - 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