Title: Book the Best BUSINESS Hotels in San Ysidro in 2026 | Expedia.ca [San Ysidro Travel Guide](https://expedia.ca/San-Ysidro.dx8380)[Hotels in San Ysidro](https://expedia.ca/San-Ysidro-Hotels.d8380.Travel-Guide-Hotels)[Vacation Rentals in San Ysidro](https://expedia.ca/San-Ysidro-Vacation-Rentals.d8380.Travel-Guide-VacationRentals)[Flights to San Ysidro](https://expedia.ca/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights)[Things to do in San Ysidro](https://expedia.ca/Things-To-Do-In-San-Ysidro.d8380.Travel-Guide-Activities)[San Ysidro Car Rentals](https://expedia.ca/Car-Rentals-In-San-Ysidro.d8380.Car-Rental-Guide)[San Ysidro Vacation Packages](https://expedia.ca/San-Ysidro.d8380.Destination-Travel-Guides) ![A fence on the United States - Mexico border where it meets the Pacific Ocean in Border Field State Park Beach](https://images.trvl-media.com/place/8380/3ab13fe2-f1be-465b-bd43-6d314810f387.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in San Ysidro, CA from CA $109 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Ysidro Business Hotels Tonight [Dec 8 - Dec 9](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-12-08&endDate=2025-12-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=8380&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top San Ysidro Business Hotels ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/a90f2d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/d8ecd896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/18bcfb40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798071/58b6effd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites San Ysidro, CA -San Diego South Bay San Ysidro 7.8/10 Good (1388) "Excelente hotel " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Adrian Andrés CA $96 CA $109 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Ysidro-Hotels-Studio-6-Suites-San-Ysidro.h1798071.Hotel-Information) ![Desk, blackout drapes, soundproofing, free WiFi](https://images.trvl-media.com/lodging/35000000/34910000/34909900/34909853/60b7030b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, soundproofing, free WiFi](https://images.trvl-media.com/lodging/35000000/34910000/34909900/34909853/06274c72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34910000/34909900/34909853/7aa1b6a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/35000000/34910000/34909900/34909853/5b5e2b75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Valli Hi Motel San Ysidro 8.2/10 Very good (1004) "We stay here when we have an early flight out of Tijuana - convenient to the cbx border crossing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sergio CA $122 CA $140 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/San-Ysidro-Hotels-Valli-Hi-Motel.h34909853.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/f294be65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/d3b44b8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/1b688cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/571600/571545/16da1e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza San Diego - Mission Valley by IHG Mission Valley 7.8/10 Good (1008) "Good value Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $117 CA $136 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Diego-Hotels-Crowne-Plaza-San-Diego-Mission-Valley.h571545.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/858/c5325c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse](https://images.trvl-media.com/lodging/1000000/10000/900/858/36c2b78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/900/858/c6795882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/900/858/543624c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Mission Bay Spa and Marina Mission Bay 8.4/10 Very good (1567) "Loved our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy CA $160 CA $258 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/San-Diego-Hotels-Hyatt-Regency-Mission-Bay-Spa-And-Marina.h858.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking, Bay View](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/66a8936b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/1a09735e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/1e0934c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The DEXTRO Little Italy, BW Premier Collection Downtown San Diego 8.8/10 Excellent (718) "Great little boutique hotel ! Friendly staff as well" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Caroll CA $143 CA $165 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/77e4221b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/7c98a26c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/76b95bec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn San Diego/Mission Valley Mission Valley 8.8/10 Excellent (1273) "Spacious and clean rooms, helpful staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gholam CA $139 CA $160 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/9fc82331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/2df2def5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/f10fc62f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront Downtown San Diego 8.6/10 Excellent (1852) "Enjoyed my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon CA $112 CA $198 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Room, 1 King Bed with Sofa bed, Marina View | View from room](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/16e63028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast, lunch, dinner served; Mexican cuisine](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/b3296075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/1e020b70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton San Diego Resort Harbor Island 8.2/10 Very good (3180) "Great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa CA $130 CA $199 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Hypo-allergenic bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/a9d9fb29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/0b3061e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/431e6d92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/65055fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manchester Grand Hyatt San Diego Downtown San Diego 9.0/10 Wonderful (2871) "It was nice and the bar up top was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brent CA $243 CA $357 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/1b87fc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hospitality Suite, 1 King Bed, Bay View | Living room](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/d02824a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/2ba9fb5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, white sand](https://images.trvl-media.com/lodging/1000000/30000/27600/27516/31f9c777.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Diego Bayview Downtown San Diego 8.6/10 Excellent (1050) "I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alliyah CA $187 CA $257 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/San-Diego-Hotels-The-Westin-San-Diego-Downtown.h27516.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-22&endDate=2025-12-23®ionId=8380&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top San Ysidro Hotel Reviews ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "The room was great! Loved the view! Staff was so nice! Room service does a great job at making virgin piña colada’s! Great location! only one complaint is it’s a little loud but it quiet down after 10! " [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "What a great staff on all shifts. I mean everyone was helpful and didn’t have no hesitation to answering questions! They weren’t rude in any way! Great service!!!!! Thank you!!!!" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Clean spacious room" [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Sheraton Mission Valley San Diego Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Decent room, great staff and close to am" [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Was great! " [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "The room was very clean and the staff was friendly and helpful. The restaurant had good food. The waitstaff were very responsive to requests and very professional." [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Room was clean and staffs were courteous. " [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Check in process is always effortless as staff is well trained. This retro vintage property is in amazing shape, which is no easy feat. This is my third time to stay here and it is a favorite for us as the property just has so much character, and having the world famous Waffle Spot on property for breakfast helps everyone's day start out great. Thanks again team for making our trip awesome and trouble free." [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Great stay! " [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ## Frequently asked questions ### Which hotels to stay in San Ysidro as a business traveler? > Another excellent choice is the BORDER PLAZA HOTEL, boasting an exceptional score of 9.4\. It provides free self-parking and Wi-Fi, alongside accessible parking, suiting the needs of all guests. Its location is convenient for business activities, and travellers often highlight the welcoming atmosphere, making it a reliable option for those on work trips. > > > If you're looking for a budget-friendly option, consider the [Valli Hi Motel](https://www.expedia.ca/San-Ysidro-Hotels-Valli-Hi-Motel.h34909853.Hotel-Information), which has a rating of 8.2\. It offers free self-parking and Wi-Fi, and guests praise the comfortable, clean rooms and the excellent customer service provided by the friendly staff. This motel is particularly noted for its convenient location, making it a practical choice for business travellers on the go. > > > Lastly, while not as highly rated, the [Hotel Baja San Diego - A Boutique Hotel](https://www.expedia.ca/San-Ysidro-Hotels-Hotel-Baja-San-Diego.h482151.Hotel-Information) offers a complimentary continental breakfast on weekends and a relaxed atmosphere, making it suitable for a laid-back business stay. ### How much does a business hotel in San Ysidro cost? ### What San Ysidro business hotels offer complimentary breakfast? > Another option is the [Hotel Baja San Diego - A Boutique Hotel](https://www.expedia.ca/San-Ysidro-Hotels-Hotel-Baja-San-Diego.h482151.Hotel-Information), which offers a delightful continental breakfast free of charge. With a review score of 7.4, guests appreciate the excellent service from the staff and the pleasant breakfast experience that sets a positive tone for their day. This hotel is particularly appealing for those who enjoy a more intimate setting while still being close to the business hubs of San Ysidro. ### Which area of San Ysidro is best to stay in for business? > For those travelling with colleagues or clients, the nearby Plaza del Rio offers a blend of business and leisure. With modern meeting spaces and excellent dining options, it's great for hosting meetings or unwinding after a busy day. Enjoying dinner at one of the local restaurants, where you can sample authentic Mexican cuisine, can be a delightful way to strengthen professional relationships. > > > Families accompanying business travellers will appreciate the family-friendly facilities in the area. Hotels often provide amenities like pools and play areas, allowing for a relaxing environment after a day of meetings. Additionally, the nearby Tijuana River National Estuarine Research Reserve offers a chance for a peaceful escape with nature trails and birdwatching opportunities. ### What business amenities should I look for in a hotel in San Ysidro? ### How can I save on a business hotel in San Ysidro with Expedia? ### Can I cancel my business hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Beach Hotel Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Beach-Hotel.0-0-d6068523-tBeachHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Hotels-With-Indoor-Pool.0-0-d6068523-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Camp Pendleton Marine Corps Base ](https://www.expedia.ca/Camp-Pendleton-Marine-Corps-Base-Hotels-Oceanfront-Hotels.0-0-d6068523-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - 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