San Fransisco District Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

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    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Top San Fransisco District Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9/10 Wonderful! (925 reviews)
Love the location and the restaurant inside the hotel was phenomenal.

Reviewed on Jul. 11, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
per person
Sep 1 - Sep 9
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Panama City (PTY)
No reviews
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
Sep 24 - Oct 2
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to Panama City (PTY)
8.8/10 Excellent! (143 reviews)
Good place for relax and enjoy good vacations with the family

Reviewed on Apr. 6, 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
Save 100% on your flight
per person
Sep 24 - Oct 2
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to Panama City (PTY)
9.4/10 Exceptional! (82 reviews)
Wow! This resort is absolutely amazing! Bekar went above and beyond for us! He even brought in a TV to the lobby so we could watch the NHL playoff game! Food is 10/10 as well. We will definitely go back!

Reviewed on May 18, 2025

Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
Bella Vista
Save 100% on your flight
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
The customer service was top tier and the concierge, Lil always made the best record!

Reviewed on Jul. 14, 2025

San Fransisco District Hotel Deals

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is CA $96 per night from Jul 17 to Jul 18
CA $96
CA $106 total
Jul 17 - Jul 18
includes taxes & fees
8.4/10 Very Good! (310 reviews)
"I did not like the stale smell in the room when I entered it and the smell was persistent."

Reviewed on Jun. 12, 2025

Hotel Gran David
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is CA $105 per night from Jul 17 to Jul 18
CA $105
CA $118 total
Jul 17 - Jul 18
includes taxes & fees
8.8/10 Excellent! (519 reviews)
Good hotel ran by a great staff!
"The staff was friendly and helpful. Pool is one of my favorites clean with a swim up bar. Good breakfast buffet. I was there for a graduation ceremony, a good facility for that as well."

Reviewed on Jul. 13, 2025

Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
Fully refundableReserve now, pay when you stay
The price is CA $105 per night from Jul 16 to Jul 17
CA $105
CA $115 total
Jul 16 - Jul 17
includes taxes & fees
9.2/10 Wonderful! (60 reviews)
"Very clean, food was 10/10"

Reviewed on Jul. 10, 2025

HOTEL VISTA LAGO
See all 25 properties in San Fransisco District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does a San Fransisco District vacation package cost?
Our San Fransisco District packages, which begin from just CA $1,340, are an easy way to save precious money. All you have to do is choose your favorite hotels, flights and more to create your ideal escape.
How do I get a cheap travel package to San Fransisco District?
Book everything all in one place with our San Fransisco District vacation packages. You'll find bargains on hotels, flights, tours and more that'll keep your pocketbook happy and your adventurous spirit busy. And, with more than 550 partner airlines and 1,000,000 properties throughout the world to choose from, you'll have endless opportunities to mix and match however you please.
How far in advance should I book my San Fransisco District vacation?
It's difficult to pick the best time for airfares, but we generally say the earlier, the better. Most international flights on Expedia become available up to a year in advance. If you can't book ahead, don't stress. Bargain prices occasionally appear within a few weeks of departure dates.
What does an Expedia San Fransisco District travel package include?
Car rentals, hotels and flights --- we connect you to all the best deals. All you have to do is select your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to customize an exciting San Fransisco District getaway.
What should I know before booking a San Fransisco District travel package?
A package can be easier on the bank balance than separately booking everything you need for your adventure. For example, combine your hotels, flights and rental cars and score impressive savings. No matter your vacation goals, there's sure to be a package that matches your budget.
Can I choose my airline with a San Fransisco District Expedia vacation package?
Yes --- that's the beauty of an Expedia package. You can pick and choose your flights, hotels and more. We have more than 550 airline partners throughout the world, so you have options galore when creating your San Fransisco District escape.
If I'm not able to travel, can I cancel my San Fransisco District vacation package?
If your vacation plans in San Fransisco District have changed, it's a relief to know that you can amend or cancel your booking. If your booking was made in the last 24 hours, you may be able to get a refund. If your booking is older than that, your airline, hotel or car rental company may impose a cancellation fee. To find out more, visit our Customer Service Portal.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.