San Francisco Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top San Francisco Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City
San Francisco
CA $1,281
per person
Nov 8 - Nov 14
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
8.6/10 Excellent! (1,719 reviews)
The location of the property is convenient however updated renovations to the room decor would be nice
Reviewed on Oct 1, 2026
Central Hotel Panama Casco Viejo
Casco Viejo
CA $1,945
per person
Nov 8 - Nov 14
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (1,007 reviews)
This is a great hotel, and the location was perfect. The rooms were nice, and the staff were very friendly. I would highly recommend it.
Reviewed on Oct 1, 2026
Megapolis Hotel Panamá
San Francisco
CA $1,304
per person
Nov 8 - Nov 14
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
8.6/10 Excellent! (1,743 reviews)
Where can I start?! First of all the hotel is connected to the mall by a crosswalk!!! The food, drinks, aesthetics, staff, location, all amazing I’m definitely booking the same hotel when I return. Uber was $5 max to local spots. Shout out to the breakfast buffett staff. Best I’ve ever had. The fresh watermelon juice was perfect!!!! Room view was killer!! So many photo ops! Every corner of this ginormous build was McCullen’s and the hotel smelled like an expensive perfume.
Reviewed on Oct 1, 2026
Yoo by Wynwood House
Calidonia
CA $2,804
per person
Dec 23 - Dec 30
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.
Reviewed on Jul 26, 2025
Ready to book your vacation to San Francisco?
San Francisco Hotel Deals
Hotel Mykonos Panama
Panamerican Highway Nuevo Santiago Veraguas
CA $111
CA $124 total
Oct 20 - Oct 21
includes taxes & fees
Hotel Gran David
Vía Interamericana Santiago Veraguas
CA $109
CA $119 total
Oct 7 - Oct 8
includes taxes & fees
HOTEL VISTA LAGO
Rincón Largo La Pena Santiago de Veraguas
CA $99
CA $110 total
Oct 2 - Oct 3
includes taxes & fees
9.4/10 Exceptional! (126 reviews)
"Todo perfecto"
Reviewed on Sep 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a San Francisco vacation package cost?
Offering excellent value package deals from CA $1,281 on Expedia, you'll be pleasantly surprised at how much a vacation to San Francisco costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to San Francisco?
If you'd like to score a cheap San Francisco vacation package, consider travelling in September, October and November. You're likely to find lower prices on airfares and hotels during these months — perfect for a budget-friendly break.
How many days is enough for San Francisco?
Typically, a handful of days is enough to tick off the top attractions during your San Francisco vacation. But if you'd like to have more time to relax or take day trips, think about extending your itinerary.
How to find the best San Francisco package deals?
Start your search for a San Francisco package deal by entering your preferred travel dates and destination under our "Packages" tab. Then apply some filters, like "Popular locations" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect San Francisco package deal straight away, simply switch up your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your San Francisco adventure off to a flying start.
Is it cheaper to book a San Francisco vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component individually. And you'll still get the flexibility to create a customized San Francisco vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to San Francisco?
If you have your San Francisco vacation dates confirmed, book as early as you can to score some awesome deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for jetting off on a whim.
How to plan a trip to San Francisco?
- Choose when to travel: Check your calendar and get packing. Your favourite season and the activities on offer will also help you decide when to escape to San Francisco.
- Work out your budget: Make sure you have enough money to pay for everything from meals and transportation to activities and airfares. Your accommodations will likely be the biggest expense during your trip to San Francisco.
- Set the duration of your trip: Start by making a list of all the sights and activities you want to get to in San Francisco. Then, estimate how long you'll need for each, including any travel time.
- Bundle your airfare and accommodations: Once you've nailed down your trip dates and duration, lock in the right San Francisco vacation package for you.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
