Title: San Cosme y Damian Vacation Packages & Trips 2025/2026 from CA $512 | Expedia.ca [San Cosme y Damian Travel Guide](https://expedia.ca/San-Cosme-Y-Damian.dx6348319)[Hotels in San Cosme y Damian](https://expedia.ca/San-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels)[Vacation Rentals in San Cosme y Damian](https://expedia.ca/San-Cosme-Y-Damian-Vacation-Rentals.d6348319.Travel-Guide-VacationRentals)[San Cosme y Damian Car Rentals](https://expedia.ca/Car-Rentals-In-San-Cosme-Y-Damian.d6348319.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # San Cosme y Damian Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence ### Better together Save up to CA $1,096 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Plan, book, and manage your trip all in one place ## Top San Cosme y Damian Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Rio Hotel & Casino, a Destination by Hyatt Hotel](https://images.trvl-media.com/lodging/1000000/20000/19900/19837/w2160h1608x0y0-e07688de_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Rio Hotel & Casino, a Destination by Hyatt Hotel CA $512 per person Dec 2 - Dec 6 found 2 days ago Roundtrip flight included Vancouver (YVR) to Las Vegas (LAS) 7.6/10 Good! (6,093 reviews) Had to call every day for towels, room service did not come except for 1 day of our 5 day stay and did not restock the toilet paper which was very low the day they did come to clean. Nowhere to eat breakfast except a starbucks. Reviewed on Sep 24, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-02/2025-12-06/?FromAirport=YVR&Destination=LAS&NumRoom=1&NumAdult=2&NumChild=0&hotelId=19837&paandie=true&dealMarker=mKqSXSJvG3Q-WqXgBjDvseOkZ9vtXzl3YJi7HnTRXWFDhl_zgtsciW-djJp7liIE) ![Mandalay Bay Resort And Casino](https://images.trvl-media.com/lodging/1000000/210000/203700/203613/41bd5b9c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mandalay Bay Resort And Casino Las Vegas Strip CA $929 per person Dec 2 - Dec 6 found 1 day ago Roundtrip flight included Vancouver (YVR) to Las Vegas (LAS) 8.6/10 Excellent! (13,880 reviews) Getting to be outdated and crowded in certain spaces and needing more options for families and convenience items, but still clean and comfortable Reviewed on Sep 24, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-02/2025-12-06/?FromAirport=YVR&Destination=LAS&NumRoom=1&NumAdult=2&NumChild=0&hotelId=203613&paandie=true&dealMarker=twH7WvKE_Di3zIgpq2NHXkr1yJgnSMrin_kN295b9pSnED9fwL5twGMuOznk-2LH) ![Planet Hollywood Resort & Casino](https://images.trvl-media.com/lodging/1000000/20000/15200/15117/a52b2119_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Planet Hollywood Resort & Casino Las Vegas Strip CA $1,433 per person Dec 2 - Dec 6 found 1 day ago Roundtrip flight included Vancouver (YVR) to Las Vegas (LAS) 8/10 Very Good! (18,795 reviews) Clean room, friendly staff. Pool was a disappointment not a lot of room unless you rent something Reviewed on Sep 24, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-02/2025-12-06/?FromAirport=YVR&Destination=LAS&NumRoom=1&NumAdult=2&NumChild=0&hotelId=15117&paandie=true&dealMarker=twH7WvKE_Di3zIgpq2NHXkr1yJgnSMrin_kN295b9pTbg4Ia24iA3OmaP3pWeTd3) ![Los Angeles Deluxe Suites - 2 Bedrooms & 2 Bathrooms](https://images.trvl-media.com/lodging/99000000/98270000/98260500/98260496/ebc393eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Los Angeles Deluxe Suites - 2 Bedrooms & 2 Bathrooms Hollywood CA $1,109 per person Nov 11 - Nov 18 found 3 hours ago Roundtrip non-stop flight included Calgary (YYC) to Los Angeles (LAX) 9.2/10 Wonderful! (75 reviews) Beds were good altough the bed covers were stained everything else was good. Reviewed on Jul 31, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-11-11/2025-11-18/?FromAirport=YYC&Destination=LAX&NumRoom=1&NumAdult=2&NumChild=0&hotelId=98260496&paandie=true&dealMarker=7NiB-A02FFij052FyyfDv939CncNiNKnetX8-YkHZKFlrrigP4k-hva0aZB3xJyE) ![The Retreat Collection at 1 Hotel & Homes South Beach](https://images.trvl-media.com/lodging/13000000/12320000/12316600/12316590/dffb9d2c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Retreat Collection at 1 Hotel & Homes South Beach South Beach CA $16,780 per person Nov 8 - Nov 15 found 3 hours ago Roundtrip flight included Vancouver (YVR) to Miami (MIA) 8/10 Very Good! (1 review) [](https://expedia.ca/go/package/search/FlightHotel/2025-11-08/2025-11-15/?FromAirport=YVR&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&hotelId=12316590&paandie=true&dealMarker=7NiB-A02FFij052FyyfDv4rBdPO5V4Zt0sPYEBvR6NJY_WTF9p1nKTB6coeR3ZJL) ## Ready to book your vacation to San Cosme y Damian? Choose your dates ## San Cosme y Damian Hotel Deals ![Awa Resort Hotel](https://images.trvl-media.com/lodging/16000000/15370000/15363400/15363309/28eceae7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Awa Resort Hotel Ruta 1 Km 367, Calles Tajy y Naranjal, Encarnacion CA $68 CA $75 total Oct 1 - Oct 2 includes taxes & fees 8.8/10 Excellent! (111 reviews) "Awesome stay !!" Reviewed on Aug 31, 2025 [](https://expedia.ca/Hotel-Search?startDate=01%2F10%2F2025&endDate=02%2F10%2F2025&selected=15363309&PinnedHotelID=15363309&HadPinnedHotel=true®ionId=6348319) ![Carnaval Hotel Casino](https://images.trvl-media.com/lodging/13000000/12600000/12599700/12599683/3c7f3c91_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Carnaval Hotel Casino Av. Irrazabal, 750, Encarnacion Fully refundableReserve now, pay when you stay CA $90 CA $99 total Oct 5 - Oct 6 includes taxes & fees 9.2/10 Wonderful! (150 reviews) "El restaurant y desayuno era muy básico pero estaba ok" Reviewed on Sep 21, 2025 [](https://expedia.ca/Hotel-Search?startDate=05%2F10%2F2025&endDate=06%2F10%2F2025&selected=12599683&PinnedHotelID=12599683&HadPinnedHotel=true®ionId=6348319) ![Hotel Luxsur](https://images.trvl-media.com/lodging/14000000/13330000/13327300/13327276/fa70e6e0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Luxsur Jorge Memmel 661, c/ Independencia Nacional, Encarnacion Fully refundableReserve now, pay when you stay CA $94 CA $104 total Sep 25 - Sep 26 includes taxes & fees 8.8/10 Excellent! (148 reviews) "The breakfast was good. rooms were clean" Reviewed on Feb 6, 2025 [](https://expedia.ca/Hotel-Search?startDate=25%2F09%2F2025&endDate=26%2F09%2F2025&selected=13327276&PinnedHotelID=13327276&HadPinnedHotel=true®ionId=6348319) [See all 31 properties in Itapúa Department](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=25%2F09%2F2025&endDate=26%2F09%2F2025®ionId=553248635975176941) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)