Title: Visit San Cosme y Damian: Best of San Cosme y Damian Tourism | Expedia Travel Guide - Expedia.ca [Hotels in San Cosme y Damian](https://expedia.ca/San-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels)[Vacation Rentals in San Cosme y Damian](https://expedia.ca/San-Cosme-Y-Damian-Vacation-Rentals.d6348319.Travel-Guide-VacationRentals)[San Cosme y Damian Car Rentals](https://expedia.ca/Car-Rentals-In-San-Cosme-Y-Damian.d6348319.Car-Rental-Guide)[San Cosme y Damian Vacation Packages](https://expedia.ca/San-Cosme-Y-Damian.d6348319.Destination-Travel-Guides) # San Cosme y Damian ## Travel Guide ## Visit San Cosme y Damian Things to do ## Check San Cosme y Damian hotel availability [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-28&endDate=2025-10-29) [Tonight](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-28&endDate=2025-10-29) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-28&endDate=2025-10-29) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-28&endDate=2025-10-29)[Oct 28 - Oct 29](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-28&endDate=2025-10-29) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-29&endDate=2025-10-30) [Tomorrow night](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-29&endDate=2025-10-30) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-29&endDate=2025-10-30) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-29&endDate=2025-10-30)[Oct 29 - Oct 30](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-10-29&endDate=2025-10-30) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [This weekend](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025)[Oct 31 - Nov 2](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=07%2F11%2F2025&endDate=09%2F11%2F2025) [Next weekend](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=07%2F11%2F2025&endDate=09%2F11%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=07%2F11%2F2025&endDate=09%2F11%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=07%2F11%2F2025&endDate=09%2F11%2F2025)[Nov 7 - Nov 9](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=07%2F11%2F2025&endDate=09%2F11%2F2025) ### Popular places to visit #### Buenaventura Suarez Planetarium You can spend time browsing the exhibits at Buenaventura Suarez Planetarium during your travels in San Cosme y Damian. Take in the museums while you're in the area. [](https://expedia.ca/Buenaventura-Suarez-Planetarium-Encarnacion.d553248621532463875.Vacation-Attraction) #### Guarani Jesuit Ruins of San Cosme and San Damián Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area. [](https://expedia.ca/Guarani-Jesuit-Ruins-Of-San-Cosme-And-San-Damian-San-Cosme-y-Damian.d812269535561961472.Vacation-Attraction) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Other - [Bella Vista Hotels](https://www.expedia.ca/Bella-Vista-Hotels.d6141312.Travel-Guide-Hotels) - [Encarnacion Hotels](https://www.expedia.ca/Encarnacion-Hotels.d6141802.Travel-Guide-Hotels) - [Jesús Hotels](https://www.expedia.ca/Jesus-Hotels.d6353265.Travel-Guide-Hotels) - [Trinidad Hotels](https://www.expedia.ca/Trinidad-Hotels.d6141611.Travel-Guide-Hotels) - [Flights to Bella Vista](https://www.expedia.ca/Cheap-Flights-To-Bella-Vista.d6141312.Travel-Guide-Flights) - [Flights to Encarnacion](https://www.expedia.ca/Cheap-Flights-To-Encarnacion.d6141802.Travel-Guide-Flights) - [Encarnacion Vacations](https://www.expedia.ca/Encarnacion.d6141802.Destination-Travel-Guides) - [Jesús Vacations](https://www.expedia.ca/Jesus.d6353265.Destination-Travel-Guides) - [Trinidad Vacations](https://www.expedia.ca/Trinidad.d6141611.Destination-Travel-Guides) - [Things to do in Encarnacion](https://www.expedia.ca/Things-To-Do-In-Encarnacion.d6141802.Travel-Guide-Activities) - Cities near San Cosme y Damian ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)