Title: Book The Best Hotels in San Cosme y Damian for 2026 from CA $83 - Fully Refundable Options - Expedia.ca [San Cosme y Damian Travel Guide](https://expedia.ca/San-Cosme-Y-Damian.dx6348319)[Vacation Rentals in San Cosme y Damian](https://expedia.ca/San-Cosme-Y-Damian-Vacation-Rentals.d6348319.Travel-Guide-VacationRentals)[San Cosme y Damian Car Rentals](https://expedia.ca/Car-Rentals-In-San-Cosme-Y-Damian.d6348319.Car-Rental-Guide)[San Cosme y Damian Vacation Packages](https://expedia.ca/San-Cosme-Y-Damian.d6348319.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in San Cosme y Damian from CA $83 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 2 - Jan 3](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2026-01-02&endDate=2026-01-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 3 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2026-01-03&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels) ## More cheap stays in San Cosme y Damian ![Puesta del Sol by Nobile](https://images.trvl-media.com/lodging/16000000/15240000/15237500/15237430/560dc4db_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Puesta del Sol by Nobile 14 de Mayo 44 Esq. Av. Francia Encarnacion Itapua CA $75 CA $83 total Jan 12 - Jan 13 includes taxes & fees 8.6/10 Excellent! (48 reviews) [](https://expedia.ca/Encarnacion-Hotels-Hotel-Puesta-Del-Sol.h15237430.Hotel-Information) ![Apartament central with river views pool](https://images.trvl-media.com/lodging/104000000/103160000/103150100/103150003/ea823cad_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apartament central with river views pool Paraguayan Railways Encarnacion Itapúa Department [Get rates](https://expedia.ca/Hotel-Search?startDate=17%2F01%2F2026&endDate=18%2F01%2F2026&selected=103150003&PinnedHotelID=103150003&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Apartament-Central-With-River-Views-Pool.h103150003.Hotel-Information) ![Hermosa Casa de 3 Dormitorios 🤩](https://images.trvl-media.com/lodging/106000000/105890000/105886800/105886780/c6b64097_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hermosa Casa de 3 Dormitorios 🤩 Encarnación Itapúa [Get rates](https://expedia.ca/Hotel-Search?startDate=17%2F01%2F2026&endDate=18%2F01%2F2026&selected=105886780&PinnedHotelID=105886780&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Hermosa-Casa-De-3-Dormitorios.h105886780.Hotel-Information) ![Terwindt Hotel](https://images.trvl-media.com/lodging/30000000/29060000/29059400/29059377/1100e8de_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Terwindt Hotel Lomas Valentinas 1152 e Wissen y corá Encarnacion [Get rates](https://expedia.ca/Hotel-Search?startDate=17%2F01%2F2026&endDate=18%2F01%2F2026&selected=29059377&PinnedHotelID=29059377&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Terwindt-Hotel.h29059377.Hotel-Information) ![Casa de la Y, b&b, your place in Encarnación, close to everything.](https://images.trvl-media.com/lodging/122000000/121120000/121110200/121110117/c96014ea_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa de la Y, b&b, your place in Encarnación, close to everything. Encarnación Itapúa [Get rates](https://expedia.ca/Hotel-Search?startDate=17%2F01%2F2026&endDate=18%2F01%2F2026&selected=121110117&PinnedHotelID=121110117&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Vrbo-Property.h121110117.Hotel-Information) ## Frequently asked questions ### When is the best time to go to San Cosme y Damian? > During the peak season, from December to February, the area attracts tourists looking to experience its vibrant culture and stunning scenery. With various festivities and local events taking place, January provides a lively atmosphere, superb for immersing yourself in the local traditions and enjoying the warm hospitality of the residents. > > > For those who relish a more tranquil experience, May can be a wonderful alternative. During this month, the weather remains warm, while you'll find fewer crowds, allowing for a more relaxed exploration of the region's charm. You can enjoy the beauty of the area without feeling rushed, making it an excellent choice for couples or families seeking quality time together. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a San Cosme y Damian hotel booking with Expedia? ### How much is the nightly rate at a San Cosme y Damian hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Other - [Bella Vista Hotels ](https://www.expedia.ca/Bella-Vista-Hotels.d6141312.Travel-Guide-Hotels) - [Encarnacion Hotels ](https://www.expedia.ca/Encarnacion-Hotels.d6141802.Travel-Guide-Hotels) - [Jesús Hotels ](https://www.expedia.ca/Jesus-Hotels.d6353265.Travel-Guide-Hotels) - [Trinidad Hotels ](https://www.expedia.ca/Trinidad-Hotels.d6141611.Travel-Guide-Hotels) - [Flights to Bella Vista ](https://www.expedia.ca/Cheap-Flights-To-Bella-Vista.d6141312.Travel-Guide-Flights) - [Flights to Encarnacion ](https://www.expedia.ca/Cheap-Flights-To-Encarnacion.d6141802.Travel-Guide-Flights) - [Encarnacion Vacations ](https://www.expedia.ca/Encarnacion.d6141802.Destination-Travel-Guides) - [Jesús Vacations ](https://www.expedia.ca/Jesus.d6353265.Destination-Travel-Guides) - [Trinidad Vacations ](https://www.expedia.ca/Trinidad.d6141611.Destination-Travel-Guides) - [Things to do in Encarnacion ](https://www.expedia.ca/Things-To-Do-In-Encarnacion.d6141802.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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