Title: Book The Best Hotels in San Cosme y Damian for 2025 from CA $80 - Competitive Prices - Expedia.ca [San Cosme y Damian Travel Guide](https://expedia.ca/San-Cosme-Y-Damian.dx6348319)[Vacation Rentals in San Cosme y Damian](https://expedia.ca/San-Cosme-Y-Damian-Vacation-Rentals.d6348319.Travel-Guide-VacationRentals)[San Cosme y Damian Car Rentals](https://expedia.ca/Car-Rentals-In-San-Cosme-Y-Damian.d6348319.Car-Rental-Guide)[San Cosme y Damian Vacation Packages](https://expedia.ca/San-Cosme-Y-Damian.d6348319.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in San Cosme y Damian from CA $80 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 17 - Nov 18](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2025-11-17&endDate=2025-11-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 18 - Nov 19](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2025-11-18&endDate=2025-11-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6348319&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 32 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels) ## More cheap stays in San Cosme y Damian ![Puesta del Sol by Nobile](https://images.trvl-media.com/lodging/16000000/15240000/15237500/15237430/560dc4db_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Puesta del Sol by Nobile 14 de Mayo 44 Esq. Av. Francia Encarnacion Itapua CA $73 CA $80 total Nov 20 - Nov 21 includes taxes & fees 8.6/10 Excellent! (48 reviews) [](https://expedia.ca/Encarnacion-Hotels-Hotel-Puesta-Del-Sol.h15237430.Hotel-Information) ![Apartament central with river views pool](https://images.trvl-media.com/lodging/104000000/103160000/103150100/103150003/ea823cad_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apartament central with river views pool Paraguayan Railways Encarnacion Itapúa Department [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F12%2F2025&endDate=02%2F12%2F2025&selected=103150003&PinnedHotelID=103150003&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Apartament-Central-With-River-Views-Pool.h103150003.Hotel-Information) ![Hermosa Casa de 3 Dormitorios 🤩](https://images.trvl-media.com/lodging/106000000/105890000/105886800/105886780/c6b64097_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hermosa Casa de 3 Dormitorios 🤩 Encarnación Itapúa [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F12%2F2025&endDate=02%2F12%2F2025&selected=105886780&PinnedHotelID=105886780&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Hermosa-Casa-De-3-Dormitorios.h105886780.Hotel-Information) ![Terwindt Hotel](https://images.trvl-media.com/lodging/30000000/29060000/29059400/29059377/1100e8de_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Terwindt Hotel Lomas Valentinas 1152 e Wissen y corá, Encarnacion [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F12%2F2025&endDate=02%2F12%2F2025&selected=29059377&PinnedHotelID=29059377&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Terwindt-Hotel.h29059377.Hotel-Information) ![Casa de la Y, b&b, your place in Encarnación, close to everything.](https://images.trvl-media.com/lodging/122000000/121120000/121110200/121110117/c96014ea_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa de la Y, b&b, your place in Encarnación, close to everything. Encarnación, Itapúa [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F12%2F2025&endDate=02%2F12%2F2025&selected=121110117&PinnedHotelID=121110117&HadPinnedHotel=true®ionId=6348319) [](https://expedia.ca/Encarnacion-Hotels-Vrbo-Property.h121110117.Hotel-Information) ## Frequently asked questions ### When is the best time to go to San Cosme y Damian? > The most popular time to visit San Cosme Y Damian is January, when the climate is pleasantly warm, offering average temperatures around 28°C. This period is ideal for enjoying the lush green landscapes and engaging in outdoor activities, making it a fantastic time for nature walks and exploring the surrounding areas. > > > > During the peak season, from December to February, the area attracts tourists looking to experience its vibrant culture and stunning scenery. With various festivities and local events taking place, January provides a lively atmosphere, superb for immersing yourself in the local traditions and enjoying the warm hospitality of the residents. > > > > For those who relish a more tranquil experience, May can be a wonderful alternative. During this month, the weather remains warm, while you'll find fewer crowds, allowing for a more relaxed exploration of the region's charm. You can enjoy the beauty of the area without feeling rushed, making it an excellent choice for couples or families seeking quality time together. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right San Cosme y Damian hotel for you. ### How can I save on a San Cosme y Damian hotel booking with Expedia? > Before booking your San Cosme y Damian hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a San Cosme y Damian hotel? > Prices for hotels in San Cosme y Damian often vary, but you can find a great deal from CA $80 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Other - [Bella Vista Hotels](https://www.expedia.ca/Bella-Vista-Hotels.d6141312.Travel-Guide-Hotels) - [Encarnacion Hotels](https://www.expedia.ca/Encarnacion-Hotels.d6141802.Travel-Guide-Hotels) - [Jesús Hotels](https://www.expedia.ca/Jesus-Hotels.d6353265.Travel-Guide-Hotels) - [Trinidad Hotels](https://www.expedia.ca/Trinidad-Hotels.d6141611.Travel-Guide-Hotels) - [Flights to Bella Vista](https://www.expedia.ca/Cheap-Flights-To-Bella-Vista.d6141312.Travel-Guide-Flights) - [Flights to Encarnacion](https://www.expedia.ca/Cheap-Flights-To-Encarnacion.d6141802.Travel-Guide-Flights) - [Encarnacion Vacations](https://www.expedia.ca/Encarnacion.d6141802.Destination-Travel-Guides) - [Jesús Vacations](https://www.expedia.ca/Jesus.d6353265.Destination-Travel-Guides) - [Trinidad Vacations](https://www.expedia.ca/Trinidad.d6141611.Destination-Travel-Guides) - [Things to do in Encarnacion](https://www.expedia.ca/Things-To-Do-In-Encarnacion.d6141802.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)