Title: Hotels by Best Western in Rochester from CA $149 | Expedia.ca [Rochester Travel Guide](https://expedia.ca/Rochester.dx3041)[Hotels in Rochester](https://expedia.ca/Rochester-Hotels.d3041.Travel-Guide-Hotels)[Vacation Rentals in Rochester](https://expedia.ca/Rochester-Vacation-Rentals.d3041.Travel-Guide-VacationRentals)[Flights to Rochester](https://expedia.ca/Cheap-Flights-To-Rochester.d3041.Travel-Guide-Flights)[Things to do in Rochester](https://expedia.ca/Things-To-Do-In-Rochester.d3041.Travel-Guide-Activities)[Rochester Car Rentals](https://expedia.ca/Car-Rentals-In-Rochester.d3041.Car-Rental-Guide)[Rochester Vacation Packages](https://expedia.ca/Rochester.d3041.Destination-Travel-Guides) ![Rochester Minnesota; Shutterstock ID 82642243](https://images.trvl-media.com/place/3041/2aa1af3e-4182-4ce9-9fc7-ca2c436d39ff.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3041/2aa1af3e-4182-4ce9-9fc7-ca2c436d39ff.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 24 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Rochester Best Western ![Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/ec5f8616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/d609b8e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2560x4y0-89209858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's [](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) Rochester 8.4/10 Very good (807 reviews) "Check in staff was great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paulette CA $130 CA $149 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-06&endDate=2026-02-07®ionId=3041&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FRochester-Hotels-Best-Western.0-0-d3041--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FRochester-Hotels-Best-Western.0-0-d3041--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Rochester Hotel Reviews ![Holiday Inn Express Rochester South - Mayo Area by IHG](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd_y.jpg) ### Holiday Inn Express Rochester South - Mayo Area by IHG 10/10 Excellent "." [](https://expedia.ca/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "When I told my husband where we were staying he was not pleased at all. He wanted something closer to the hospital.When we got there he went and checked us in and check out the room he was very pleased. There was hot drinks always ready. The room was very clean and comfortable. The staff was extremely accommodating.We will stay there again. We left to go back home and stayed in another hotel and the second we walked in the room we both said this is not the SpringHill Suites. SpringHill Suites thank you for a memorable experience." [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg) ### Home2 Suites by Hilton Rochester Mayo Clinic Area 10/10 Excellent "It has been a Great stay & very clean & quiet! Staff has been great also. " [](https://expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) ![Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys](https://images.trvl-media.com/lodging/11000000/10950000/10947300/10947270/9bad372e_y.jpg) ### Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys 10/10 Excellent "Great execution of all facets of a good hotel." [](https://expedia.ca/Rochester-Hotels-Fairfield-Inn-Suites-Rochester-Mayo-Clinic-AreaSt-Marys.h10947270.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Amazing all around! " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![The Berkman](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07_y.jpg) ### The Berkman 10/10 Excellent "Amazing" [](https://expedia.ca/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Love the restaurant… truffle fries are the best!!! Staff is great!!!" [](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg) ### Hyatt House Rochester/Mayo Clinic Area 10/10 Excellent "All the above!! Surprisingly pleasant and exceeded expectations. Expedia value was an extra bonus. " [](https://expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "The amenities and the great customer service. 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