Most Popular Panama Hotels

See all 398 Hotels in Panama
Hard Rock Hotel Panama Megapolis
Hard Rock Hotel Panama Megapolis

Ave. Balboa al lado de Multicentro, Panama City

4.5 out of 5.0
4.4 out of 5 (1,767 reviews)

This family-friendly Panama City hotel is located by the ocean, within 1 mi (2 km) of Multicentro Panama and Via Espana. …

CA$180
Wyndham Panama Albrook Mall
Wyndham Panama Albrook Mall

Ave. Marginal, Corregimiento de Ancon, Panama City

4.0 out of 5.0
4.5 out of 5 (540 reviews)

Located in the heart of Panama City, this hotel is located inside the Albrook Shopping Mall, close to the Anthropological …

CA$134
Novotel Panama City
Novotel Panama City

Calle Jose I. Fabrega y Thais de Pons, Panama City 581

4.0 out of 5.0
4.3 out of 5 (509 reviews)

Located in the heart of Panama City, this hotel is within 2 mi (3 km) of Via Espana, Multiplaza Pacific Mall, and Multicentro …

CA$76
Waldorf Astoria Panama
Waldorf Astoria Panama

47th St. & Uruguay Street, Panama City

5.0 out of 5.0
4.4 out of 5 (335 reviews)

Located in the heart of Panama City, this luxury hotel is 0.6 mi (1 km) from Via Espana and 2.2 mi (3.6 km) from Metropolitan …

CA$183
Wyndham Garden Panama City
Wyndham Garden Panama City

10 58th Street, Obarrio, Panama City

3.5 out of 5.0
3.7 out of 5 (491 reviews)

Located in the heart of Panama City, this hotel is within 1 mi (2 km) of Via Espana, Multiplaza Pacific Mall, and Multicentro …

CA$73
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel

Italy Avenue, Punta Paitilla, Panama City 081606579

3.5 out of 5.0
3.9 out of 5 (359 reviews)

Situated in Panama City, this hotel is within 2 mi (3 km) of Multicentro Panama, Multiplaza Pacific Mall, and Via Espana. …

CA$99
Radisson Summit Hotel and Golf Panama
Radisson Summit Hotel and Golf Panama

Omar Torrijos Ave, Paraiso 0844-2014

4.0 out of 5.0
4.3 out of 5 (584 reviews)

This family-friendly Paraiso hotel is located in the mountains, 3 mi (4.9 km) from Soberania National Park, and within 6 mi …

CA$88
Bristol Panama
Bristol Panama

Avenida Aquilino de La Guardia, Panama City

5.0 out of 5.0
4.6 out of 5 (299 reviews)

Located in the heart of Panama City, this luxury hotel is 0.3 mi (0.4 km) from Via Espana and 2.6 mi (4.2 km) from …

CA$204
Panama Marriott Hotel
Panama Marriott Hotel

52nd St. and Ricardo Arias, Panama City 832-0498

4.0 out of 5.0
4.4 out of 5 (206 reviews)

This Panama City hotel is less than one-quarter mile from Via España and 2.3 kilometers from Metropolitan Nature Park. Palaci …

CA$155
Wyndham Garden Panama Centro
Wyndham Garden Panama Centro

Calle D El Cangrejo, Panama City 01662

3.0 out of 5.0
3.2 out of 5 (128 reviews)

Situated in a shopping district, this hotel is 0.5 mi (0.8 km) from Via Espana and 2.9 mi (4.7 km) from Metropolitan Cathedra …

CA$77
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Panama Hotel Guide

Panama is one of Central America’s most desirable travel destinations. This inviting country is particularly famous for its unique culture, intriguing history, and alluring natural beauty. It’s also easy to find plenty of fun things to do in Panama. If you’re planning a trip to this exciting nation, you can always find deals on some of the best hotels in Panama featured here on Expedia.

Panama City is the nation’s capital city and an ideal spot for tourism. If you would like to enjoy your visit in style, you can stay in one of the upscale Panama City beach hotels and take in the spectacular views of the Pacific Ocean and Panama Canal. The district known as Panamá Viejo is the oldest part of the city and features Spanish colonial buildings dating back hundreds of years. You can also find terrific offers on quality Panama City hotels located next to popular museums such as the Panama Canal Museum and the Colonial Religious Art Museum.

The province known as Bocas del Toro is another place worth visiting. In addition to its mainland portion, a series of small islands also make up this enchanting region. You can take a walk through wilderness areas to see tropical vegetation while possibly catching a glimpse of a rare wildlife creature. A detailed travel book will provide further information on the best places to visit within this province. It is also easy to find discount rates on some of the top Bocas del Toro Panama hotels.

Tourists are likely to enjoy visits to Boquete during their Panama vacations. This small town offers you the chance to further immerse yourself in the natural splendor of the country. The Caldera River and rolling hills covered with lush green vegetation can be clearly seen while touring this town. The Boquete Panama hotels will provide you with comfortable accommodations and clean Panama hotel rooms.

The best hotels Panama has to offer are always featured here on Expedia. You can check out photos of these Panama hotels and read further information about the amenities. Panama all-inclusive hotels offer even better deals. You may even be able to find specials on some of the premier Panama boutique hotels. Expedia features low prices on hotels in Panama throughout the entire year.