Photo by Dr__Vlad
Find Hotels by Best Western in O Brien
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Top O Brien Best Western Hotels
Top O Brien Hotel Reviews
Comfort Suites Lake City
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
O Brien Hotels by Brand
Hotels near popular O Brien Attractions
- Hotels near Ichetucknee Springs State Park
- Hotels near Ginnie Spring
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Suwannee River
- Hotels near Ichetucknee River
- Hotels near Suwannee River State Park
- Hotels near Santa Fe River
- Hotels near Poe Springs Park
- Hotels near Lake City Mall
- Hotels near Southside Sports Complex
More Accommodation Types in O Brien
Explore more hotels
- Days Inn by Wyndham Lake City I-75
- Hampton Inn & Suites Lake City
- Hampton Inn & Suites Alachua I-75
- TownePlace Suites by Marriott Lake City
- Days Inn by Wyndham Lake City I-10
- Americas Best Value Inn Lake City
- Quality Inn White Springs Suwanee
- Holiday Inn Express Hotel & Suites LIVE OAK by IHG
- Fairfield Inn & Suites Lake City
- Americas Best Value Inn Alachua
- Quality Inn Lake City
- Home2 Suites by Hilton Lake City
- Palms Garden Inn
- Gateway Inn
- BlueGem Motel
- Regal Inn
- Super 8 by Wyndham Lake City
- Quality Inn & Suites Live Oak I-10 Exit 283
- The Blanche
- Vista Verde Farm Retreat