A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien Vacation Rentals

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Our top choices for O Brien vacation rentals

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
O'Brien
9.4 out of 10, Exceptional, (59 reviews)
"A great get away for Labor Day weekend to do a little jet skiing with friends on the river and visiting all the local springs!"
United States
Heather H.
The price is CA $282
CA $611 total
includes taxes & fees
Jul 7 - Jul 8
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.5 star property
High Springs
10.0 out of 10, Exceptional, (227 reviews)
"Amazing spot to be out of the world."
United States
Tati
The price is CA $253
CA $403 total
includes taxes & fees
Jul 1 - Jul 2
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Beautiful cozy cottage fully fenced near town and springs

Beautiful cozy cottage fully fenced near town and springs
High Springs
9.0 out of 10, Wonderful, (46 reviews)
"Nice clean home really close to all springs will definitely stay again and recommend to family's! Beautiful home!"
United States
Terry
The price is CA $149
CA $347 total
includes taxes & fees
Jul 13 - Jul 14
Beautiful cozy cottage fully fenced near town and springs

Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
9.8 out of 10, Exceptional, (6 reviews)
"Excellent place "
United States
Linay
The price is CA $100
CA $243 total
includes taxes & fees
Jun 28 - Jun 29
Nook at the Springs | Tiny Home • Full Kitchen

Stylish Cabin - Nearby Springs

Stylish Cabin - Nearby Springs
Lake City
10.0 out of 10, Exceptional, (5 reviews)
"Amazing place"
United States
Ernesto Randhel
The price is CA $174
CA $287 total
includes taxes & fees
Jul 19 - Jul 20
Stylish Cabin - Nearby Springs

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo
10.0 out of 10, Exceptional, (13 reviews)
"Fantastic property very quiet with very friendly animals."
United States
Hevrard
The price is CA $67
CA $122 total
includes taxes & fees
Jul 7 - Jul 8
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Mayo
10.0 out of 10, Exceptional, (12 reviews)
"Had a great weekend away- it was just what me and my girlfriend needed."
United States
Mike S.
The price is CA $68
CA $131 total
includes taxes & fees
Jun 26 - Jun 27
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Cozy 1-bedroom camper in nice High Springs with AC

Cozy 1-bedroom camper in nice High Springs with AC
High Springs
9.0 out of 10, Wonderful, (10 reviews)
"Good location"
United States
Hilton L.
The price is CA $71
CA $140 total
includes taxes & fees
Jun 24 - Jun 25
Cozy 1-bedroom camper in nice High Springs with AC

Private Retreat on 21 Acres Close to Spirit of the Suwannee

Private Retreat on 21 Acres Close to Spirit of the Suwannee
Live Oak
10.0 out of 10, Exceptional, (36 reviews)
"Fantastic place, super clean and dreamy! We had an amazing stay"
United States
Maria C.
The price is CA $130
CA $233 total
includes taxes & fees
Jun 25 - Jun 26
Private Retreat on 21 Acres Close to Spirit of the Suwannee

Fish & Float at Natural Springs! Log Cabin in Bell

Fish & Float at Natural Springs! Log Cabin in Bell
3.0 star property
Bell
10.0 out of 10, Exceptional, (1 review)
"A very nice cabin tucked away! We mostly enjoyed the chickens visiting us on the porch during morning coffee! The cabin is about 20 mins from the Springs and grocery store/market. High Springs town about 30 mins. Bring your own ice…no ice maker. If you need anything at all, the owner lives on the large property and happy to help but does respect your privacy…never saw him and the check in process was seemless. Loved the stay and sure you will as well."
United States
Beth
The price is CA $235
CA $539 total
includes taxes & fees
Jun 24 - Jun 25
Fish & Float at Natural Springs! Log Cabin in Bell

Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping

Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping
High Springs
10.0 out of 10, Exceptional, (2 reviews)
"Love, love, love this place and will definitely be coming back if they'll have us. Lots of space to play games outside and spend some time with the family without other campers right next to you. You couldn't ask for more friendly hosts, everything was easy from checking in to checking out. They showed us around the property and told us about some of the springs as well. My mom's car broke down and they let us rent it for another night last minute, they have two grills and a above ground pool...
United States
Tina O.
The price is CA $45
CA $86 total
includes taxes & fees
Jun 24 - Jun 25
Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping

The Riverhead | Springs • Pavilion • Grill

The Riverhead | Springs • Pavilion • Grill
Fort White
9.6 out of 10, Exceptional, (14 reviews)
"Very close to springs and other attractions. Property was clean and very inviting on the inside. The beds were comfortable and the decor was very homey. Ample coffee and tea was provided and the kitchen was very equipped for cooking. Overall a really great way to enjoy the nearby springs. "
United States
Nicole
The price is CA $178
CA $438 total
includes taxes & fees
Jun 29 - Jun 30
The Riverhead | Springs • Pavilion • Grill

Romantic Barn Retreat • 7 Private Acres • Fire Pit

Romantic Barn Retreat • 7 Private Acres • Fire Pit
Alachua
10.0 out of 10, Exceptional, (21 reviews)
"Everything about the stay was fantastic! "
United States
Gina R.
The price is CA $121
CA $212 total
includes taxes & fees
Jun 29 - Jun 30
Romantic Barn Retreat • 7 Private Acres • Fire Pit

Cozy Bungalow close to downtown High Springs.

Cozy Bungalow close to downtown High Springs.
High Springs
10.0 out of 10, Exceptional, (16 reviews)
"Great place with all the extra touches. I’d highly recommend to anyone staying in the area!"
United States
Cheryl
The price is CA $188
CA $409 total
includes taxes & fees
Jun 29 - Jun 30
Cozy Bungalow close to downtown High Springs.

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Branford
10.0 out of 10, Exceptional, (9 reviews)
"Very cozy, comfortable cabin with lots of activities. "
United States
Dorothy G.
The price is CA $207
CA $388 total
includes taxes & fees
Jun 24 - Jun 25
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style
Lake City
8.2 out of 10, Very good, (55 reviews)
"Very relaxing!"
United States
Gary S.
The price is CA $102
CA $246 total
includes taxes & fees
Jul 6 - Jul 7
Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

Sanctuary at the Springs | King Beds • Families

Sanctuary at the Springs | King Beds • Families
High Springs
9.2 out of 10, Wonderful, (34 reviews)
"We had a great stay. Probably the cleanest stay we have ever walked into. Very tastefully decorated and nice updated appliances. The 4 bedrooms with king beds was definitely a luxury for our guests. I loved the tea and coffee available along with the essential oil diffuser. Pretty quiet neighborhood as well. "
United States
Melissa G.
The price is CA $132
CA $411 total
includes taxes & fees
Jun 24 - Jun 25
Sanctuary at the Springs | King Beds • Families

Kokomo Farms - Cozy Cottage on the Farm

Kokomo Farms - Cozy Cottage on the Farm
Live Oak
9.8 out of 10, Exceptional, (14 reviews)
"Great place for nature!"
United States
Stephen
The price is CA $139
CA $220 total
includes taxes & fees
Jun 24 - Jun 25
Kokomo Farms - Cozy Cottage on the Farm

Cozy 1-bedroom house in delightful High Springs

Cozy 1-bedroom house in delightful High Springs
High Springs
10.0 out of 10, Exceptional, (4 reviews)
"This was a perfect overnight stop for my family of 3 on the way home from Orlando."
United States
Micah D.
The price is CA $128
CA $236 total
includes taxes & fees
Jun 24 - Jun 25
Cozy 1-bedroom house in delightful High Springs

< 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
Old Town
9.0 out of 10, Wonderful, (2 reviews)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
The price is CA $173
CA $547 total
includes taxes & fees
Jun 24 - Jun 25
< 1 Mi From Suwannee River, Hideaway w/ Lanai
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O Brien Hotel Reviews

Find out more about O Brien

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with O Brien. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in O Brien?

Yes, we offer vacation rentals close to well known points of interest in O Brien, or you can go with a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that O Brien has to offer?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to O Brien is MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY.

How many vacation rentals are there in O Brien?

Expedia has 5 vacation rentals for your stay in O Brien.

What’s there to see and do in O Brien?

Suwannee River and Ichetucknee River are a couple of lovely local spots to get outside and enjoy nature. Ichetucknee Springs State Park and Wes Skiles Peacock Springs State Park are a couple of places you'll find in the larger area.

What’s a vacation rental in O Brien like?

Vacation rentals are private properties you can stay in for several days or longer in O Brien. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for small groups.