A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien Vacation Rentals

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Our top choices for O Brien vacation rentals

1. Suwannee Music Park about 30 mins away. Royal Springs across the street.

Suwannee Music Park about 30 mins away. Royal Springs across the street.
O'Brien
9.6 out of 10, Exceptional, (7 reviews)
"Had a great time there for the holiday weekend.."
United States
Karen L.
The price is CA $196
CA $481 total
includes taxes & fees
Nov 13 - Nov 14
Suwannee Music Park about 30 mins away. Royal Springs across the street.

2. MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
O'Brien
9.4 out of 10, Exceptional, (60 reviews)
"A great get away for Labor Day weekend to do a little jet skiing with friends on the river and visiting all the local springs!"
United States
Heather H.
The price is CA $178
CA $460 total
includes taxes & fees
Nov 8 - Nov 9
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

3. Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
10.0 out of 10, Exceptional, (12 reviews)
"This place was very nice and clean. It had everything we needed. Its also very close to the Springs. Definitely recommend."
United States
Natasha
The price is CA $93
CA $221 total
includes taxes & fees
Nov 8 - Nov 9
Nook at the Springs | Tiny Home • Full Kitchen

4. Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo
9.4 out of 10, Exceptional, (21 reviews)
"Fantastic property very quiet with very friendly animals."
United States
Hevrard
The price is CA $56
CA $113 total
includes taxes & fees
Nov 18 - Nov 19
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

5. Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Mayo
9.4 out of 10, Exceptional, (19 reviews)
"Host was very accommodating!! The cabin and property have everything you need to enjoy your stay."
United States
Sheila S.
The price is CA $75
CA $124 total
includes taxes & fees
Nov 16 - Nov 17
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

6. The Happy House Tiny Guest House

The Happy House Tiny Guest House
Live Oak
8.6 out of 10, Excellent, (8 reviews)
"very nice tiny house style accommodation"
United States
Cara B.
The price is CA $125
CA $181 total
includes taxes & fees
Nov 8 - Nov 9
The Happy House Tiny Guest House

7. The Riverhead | Springs • Pavilion • Grill

The Riverhead | Springs • Pavilion • Grill
Fort White
9.4 out of 10, Exceptional, (17 reviews)
"Very close to springs and other attractions. Property was clean and very inviting on the inside. The beds were comfortable and the decor was very homey. Ample coffee and tea was provided and the kitchen was very equipped for cooking. Overall a really great way to enjoy the nearby springs. "
United States
Nicole
The Riverhead | Springs • Pavilion • Grill

8. RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
Mayo
8.8 out of 10, Excellent, (8 reviews)
"Love this little slice of heaven!"
United States
Crystal
The price is CA $77
CA $85 total
includes taxes & fees
Nov 8 - Nov 9
RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

9. Kokomo Farms - Cozy Cottage on the Farm

Kokomo Farms - Cozy Cottage on the Farm
Live Oak
9.8 out of 10, Exceptional, (15 reviews)
"Great place for nature!"
United States
Stephen
The price is CA $153
CA $214 total
includes taxes & fees
Nov 8 - Nov 9
Kokomo Farms - Cozy Cottage on the Farm

10. Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style
Lake City
8.4 out of 10, Very good, (58 reviews)
"Nice place."
United States
Jody
The price is CA $133
CA $289 total
includes taxes & fees
Nov 14 - Nov 15
Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

11. Cozy House, Hot Tub & Close to FL Springs

Cozy House, Hot Tub & Close to FL Springs
Branford
10.0 out of 10, Exceptional, (1 review)
"Juan was so welcoming. The house was clean and had everything we needed for a fun family getaway - and then some! Would love to stay here again. "
United States
Ashley L.
The price is CA $210
CA $366 total
includes taxes & fees
Nov 18 - Nov 19
Cozy House, Hot Tub & Close to FL Springs

12. Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Branford
10.0 out of 10, Exceptional, (13 reviews)
"Hosts are awesome, and there's enough amenities to keep any family busy for as long as they'd like. "
United States
James S.
The price is CA $188
CA $381 total
includes taxes & fees
Nov 18 - Nov 19
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

13. "The Loft" on the 11th Tee. No pets! No smoking!

"The Loft" on the 11th Tee. No pets! No smoking!
Lake City
10.0 out of 10, Exceptional, (18 reviews)
"This property is exactly as advertised - cozy, clean and well maintained in a beautiful neighborhood. We very much enjoyed staying there."
United States
Gerald S.
The price is CA $142
CA $231 total
includes taxes & fees
Nov 9 - Nov 10
"The Loft" on the 11th Tee. No pets! No smoking!

14. SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
10.0 out of 10, Exceptional, (1 review)
The price is CA $154
CA $182 total
includes taxes & fees
Nov 10 - Nov 11
SpringHouse at Convict Springs

15. The Loft Cozy Holiday Cabin on 21 Wooded Acres

The Loft Cozy Holiday Cabin on 21 Wooded Acres
Live Oak
10.0 out of 10, Exceptional, (38 reviews)
"Fantastic place, super clean and dreamy! We had an amazing stay"
United States
Maria C.
The price is CA $127
CA $228 total
includes taxes & fees
Dec 3 - Dec 4
The Loft Cozy Holiday Cabin on 21 Wooded Acres

16. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (296 reviews)
"Great place to stay for checking out the springs in the area"
United States
Katie
The price is CA $165
CA $305 total
includes taxes & fees
Dec 8 - Dec 9
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

17. Timber Loft - Cozy Cabin Near Springs

Timber Loft - Cozy Cabin Near Springs
Branford
The price is CA $189
CA $225 total
includes taxes & fees
Nov 19 - Nov 20
Timber Loft - Cozy Cabin Near Springs

18. Owl Hollow Cottage - Riverside Escape

Owl Hollow Cottage - Riverside Escape
Branford
The price is CA $202
CA $240 total
includes taxes & fees
Nov 8 - Nov 9
Owl Hollow Cottage - Riverside Escape

19. O'LE LADYBUG COTTAGE

O'LE LADYBUG COTTAGE
Lake City
9.6 out of 10, Exceptional, (58 reviews)
"Everything was great will stay again if I’m ever in the area"
United States
regina
The price is CA $136
CA $282 total
includes taxes & fees
Nov 9 - Nov 10
O'LE LADYBUG COTTAGE

20. Three Rivers Retreat

Three Rivers Retreat
Fort White
The price is CA $180
CA $404 total
includes taxes & fees
Nov 9 - Nov 10
Three Rivers Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O Brien Hotel Reviews

Find out more about O Brien

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with O Brien. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in O Brien?

Yes, we offer vacation rentals close to well known points of interest in O Brien, or you can go with a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that O Brien has to offer?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to O Brien is MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY.

How many vacation rentals are there in O Brien?

Expedia has 4 vacation rentals for your stay in O Brien.

What’s there to see and do in O Brien?

Suwannee River and Ichetucknee River are a couple of lovely local spots to get outside and enjoy nature. Ichetucknee Springs State Park and Lafayette Blue Springs State Park are a couple of places you'll find in the larger area.

What’s a vacation rental in O Brien like?

Vacation rentals are private properties you can stay in for several days or longer in O Brien. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for small groups.