Find hotels in O Brien, FL from CA $57

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Our top choices for O Brien hotels

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (18 reviews)
"Calm peaceful stay, staff was very helpful and attentive. "
United States
Patrick
The price is CA $157
CA $272 total
includes taxes & fees
May 17 - May 18
Vista Verde Farm Retreat

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (28 reviews)
"Staff was very helpful and attentive room was great great location "
United States
Madeline
The price is CA $35
CA $57 total
includes taxes & fees
May 26 - May 27
Suwannee River Rendezvous

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (606 reviews)
"Staff nice and helpful"
United States
Drew
The price is CA $89
CA $100 total
includes taxes & fees
May 17 - May 18
Palms Garden Inn

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,003 reviews)
"Low cost but worth it"
United States
Michael
The price is CA $81
CA $91 total
includes taxes & fees
May 17 - May 18
Days Inn by Wyndham Lake City I-10

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (211 reviews)
"Very happy to have stayed here. Great place, clean well designed, pretty and with all the amenities ready to use and working. Im glad I choose this place and highly recommend it."
United States
Andy
The price is CA $204
CA $346 total
includes taxes & fees
May 18 - May 19
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
7.8 out of 10, Good, (171 reviews)
"GOOD STOP FOR ONE NIGHT IF BREAKING UP TRAVEL TIME."
United States
Victoria LS
The price is CA $99
CA $111 total
includes taxes & fees
May 17 - May 18
Motel 6 – Lake City, Fl – Medical Center

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (711 reviews)
"Great counters in the bathroom!! Loved the served breakfast and dinner!"
United States
Wendy
The price is CA $86
CA $97 total
includes taxes & fees
Jun 15 - Jun 16
Super 8 by Wyndham Lake City

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (668 reviews)
"It's a great place to stay if you're going to a festival at the spirit of Suwanee music Park "
United States
Elizabeth
The price is CA $99
CA $109 total
includes taxes & fees
Jun 8 - Jun 9
Quality Inn White Springs Suwanee

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
"The staff was very nice and polite and it's very simple to get in."
United States
Ricardo
The price is CA $92
CA $104 total
includes taxes & fees
May 17 - May 18
Americas Best Value Inn Lake City

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (513 reviews)
"Wonderful place to stay"
United States
Tamela
The price is CA $127
CA $143 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn & Suites Alachua I-75

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,003 reviews)
"Rooms were clean and spacious. The kids enjoyed the pool, hot tub and breakfast. I will stay here again if we are in the area."
United States
Brandi
The price is CA $121
CA $136 total
includes taxes & fees
Jun 14 - Jun 15
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (253 reviews)
"Clean hotel, nice room, good value."
United States
Danielle
The price is CA $159
CA $179 total
includes taxes & fees
May 24 - May 25
Courtyard By Marriott Lake City

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very good, (27 reviews)
"Excellent service at reception and the room was very clean and spacious. "
United States
Antonio
The price is CA $102
CA $115 total
includes taxes & fees
May 26 - May 27
High Springs Country Inn

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,003 reviews)
"Good hotel for the price."
United States
John
The price is CA $88
CA $99 total
includes taxes & fees
May 20 - May 21
Days Inn by Wyndham Lake City I-75

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (589 reviews)
"older hotel really nicely renovated. Very charmful, comfortable beds. I stayed there because of the reviews and they were accurate. No special amenities' but great value."
United States
William
The price is CA $85
CA $96 total
includes taxes & fees
May 17 - May 18
Regal Inn

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"The staff was very nice, breakfast was good and they kept a watch on to replace any items that needed. The room was clean, the beds comfortable. We had a wonderful stay."
United States
Evelin
The price is CA $164
CA $184 total
includes taxes & fees
May 26 - May 27
Comfort Suites Lake City

Royal Inn

Royal Inn
2.0 star property
Alachua
7.2 out of 10, Good, (197 reviews)
"For the price it's an okay stay. There's a bed and a tv if you need some entertainment. So, good deal if you need an affordable place to lay your head. Staff is very nice and friendly as well. However, the beds are a little hard, fridge took a while to cool down drinks, and I had to use the microwave twice on the same item before it got hot. So, it's really up to what you are looking for."
United States
Alec
The price is CA $325
CA $366 total
includes taxes & fees
May 16 - May 17
Royal Inn

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (185 reviews)
"The parking was easy, and it’s a beautiful place. We really liked the history and decor, and the common spaces were a plus!"
United States
LEYA
The price is CA $187
CA $211 total
includes taxes & fees
May 20 - May 21
The Blanche

< 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
Old Town
10.0 out of 10, Exceptional, (1 review)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
The price is CA $167
CA $527 total
includes taxes & fees
May 17 - May 18
< 1 Mi From Suwannee River, Hideaway w/ Lanai

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,065 reviews)
"Great staff, good room, lovely breakfast"
United States
berendina
The price is CA $136
CA $152 total
includes taxes & fees
May 17 - May 18
Best Western Plus Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Hotels in O Brien with star rating

Frequently asked questions

What is the best area to stay in O Brien?
The best area to stay in O'Brien, Florida, is along the Suwannee River, particularly around the public boat ramps and access points.

This area is the main draw for visitors to O'Brien, as it provides direct access to the natural beauty and recreational opportunities of the Suwannee River. You'll find a scattering of accommodations, from holiday rentals to small, independent motels, often with direct riverfront access or just a short drive away. This allows for convenient enjoyment of activities like fishing, kayaking, and boating.

Families will find this area particularly appealing due to the easy access to water-based activities. Many properties offer amenities like barbecue areas and space for children to play, making it simple to enjoy the outdoors together. The nearby Spirit of the Suwannee Music Park also hosts various events throughout the year, which can be a fun addition to a family holiday.

For couples looking for a relaxed escape, staying by the river offers a peaceful setting. You can enjoy quiet evenings by the water, explore the river's springs, or simply unwind away from city life.
When is the best time to go to O Brien?
The best time to visit O'Brien, Florida, is typically during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is generally mild and pleasant, with comfortable temperatures, making it ideal for enjoying outdoor activities like swimming, fishing, and exploring the natural springs without the intense heat and humidity of summer or the cooler temperatures of winter. The spring also brings blooming wildflowers, adding to the area's natural beauty.

For couples looking for a relaxing escape, these shoulder seasons offer a good balance of agreeable weather and fewer crowds compared to peak summer. You'll find it easier to enjoy the tranquility of the Ichetucknee Springs State Park or the Suwannee River without feeling overwhelmed by other visitors.

Families travelling with children might also find these times more comfortable for outdoor adventures.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in O Brien.
How can I save on a O Brien hotel booking with Expedia?
Members always get our best prices. Find our best O Brien hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a O Brien hotel?
Prices for hotels in O Brien often vary, but you can find a great deal from CA $57 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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