Title: Book the Best Matlacha SPA Resorts from CA $277 - Spa Hotels in Matlacha, FL | Expedia.ca [Hotels in Matlacha](https://expedia.ca/Matlacha-Hotels.d601098.Travel-Guide-Hotels)[Vacation Rentals in Matlacha](https://expedia.ca/Matlacha-Vacation-Rentals.d601098.Travel-Guide-VacationRentals)[Things to do in Matlacha](https://expedia.ca/Things-To-Do-In-Matlacha.d601098.Travel-Guide-Activities)[Matlacha Car Rentals](https://expedia.ca/Car-Rentals-In-Matlacha.d601098.Car-Rental-Guide)[Matlacha Vacation Packages](https://expedia.ca/Matlacha.d601098.Destination-Travel-Guides) ![Matlacha](https://images.trvl-media.com/place/601098/538fd0dc-9413-438e-9a06-8740ec4e014c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Matlacha, FL from CA $277 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Matlacha Spa Hotels Tonight [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=601098&startDate=2025-12-13&endDate=2025-12-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=601098&startDate=2025-12-14&endDate=2025-12-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=601098&startDate=2025-12-19&endDate=2025-12-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=601098&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Matlacha hotels with a spa ![Massages](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/2dcc8d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/b4312f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/1051a5d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort Fort Myers [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) Fort Myers Beach 9.0/10 Wonderful (1699) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra Sue CA $227 CA $323 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/4aba0d83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, River View (Balcony)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/43311ff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/1175676c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Cape Coral Resort At Marina Village [](https://www.expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) Pelican 9.0/10 Wonderful (1003) "Excellent stay over Thanksgiving holiday!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole CA $201 CA $277 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Couples treatment rooms, body treatments, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/159252c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/62d93321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/c6ba33ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/f4e5c65a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sundial Beach Resort & Spa [](https://www.expedia.ca/Sanibel-Hotels-Sundial-Beach-Resort-Spa.h1939.Hotel-Information) Mid Island 8.6/10 Excellent (2584) "wonderful family friendly and spotless resort" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Anne CA $495 CA $627 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Sanibel-Hotels-Sundial-Beach-Resort-Spa.h1939.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ae1f7d62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand, kayaking, motor boating](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/39279b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/17d9d33f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Sanibel Harbour Resort & Spa [](https://www.expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) Punta Rassa 8.4/10 Very good (1004) "This was thr best place that we have ever stayed at. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $274 CA $340 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/a5c54d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, kayaking, fishing](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/560da633.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/a7398ba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/180000/170800/170769/b4d8e8fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tween Waters Island Resort & Spa [](https://www.expedia.ca/Fort-Myers-Hotels-Tween-Waters-Island-Resort-Spa.h170769.Hotel-Information) Captiva 8.6/10 Excellent (1001) "Stunning Beach View great Staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $400 CA $495 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Fort-Myers-Hotels-Tween-Waters-Island-Resort-Spa.h170769.Hotel-Information) ![Outdoor pool, a heated pool, sun loungers](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/a9952fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/1f6416a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/ac457bc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool, sun loungers](https://images.trvl-media.com/lodging/6000000/5430000/5427100/5427071/b3dba413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Resort Harbour Properties [](https://www.expedia.ca/Fort-Myers-Hotels-Resort-Harbour-Properties.h5427071.Hotel-Information) Punta Rassa 9.6/10 Exceptional (363) "10/10 would stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristie CA $781 CA $1,349 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Fort-Myers-Hotels-Resort-Harbour-Properties.h5427071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=601098&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Matlacha Hotel Reviews ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "It’s a beautiful place" [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![The Lighthouse Resort Inn & Suites](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "1st time staying at the Lighthouse! Absolutely a great stay can’t wait to go back!" [](https://expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "The resort was wonderful. The rooms were super clean, the staph were attentive, and the view of the ocean were terrific. The sand art contest was going in; but, even with all the extra people around, the service was top shelf. " [](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Doubletree by Hilton Fort Myers at Bell Tower Shops](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/704cf90c_y.jpg) ### Doubletree by Hilton Fort Myers at Bell Tower Shops 10/10 Excellent "Excellent hotel in a great location. Stuff was very friendly and accommodating " [](https://expedia.ca/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![Hilton Garden Inn Ft Myers](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a_y.jpg) ### Hilton Garden Inn Ft Myers 10/10 Excellent "The cleanliness really stood and the very friendly staff !" [](https://expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![The Westin Cape Coral Resort At Marina Village](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e_y.jpg) ### The Westin Cape Coral Resort At Marina Village 10/10 Excellent "Excellent stay over Thanksgiving holiday!" [](https://expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Sundial Beach Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/2000/1939/5481c209_y.jpg) ### Sundial Beach Resort & Spa 10/10 Excellent "What you want and expect on a beach trip, loved it" [](https://expedia.ca/Sanibel-Hotels-Sundial-Beach-Resort-Spa.h1939.Hotel-Information) ![Marriott Sanibel Harbour Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg) ### Marriott Sanibel Harbour Resort & Spa 10/10 Excellent "The staff was extremely friendly. Property is beautiful. " [](https://expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/81b75b6a_y.jpg) ### Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral 10/10 Excellent "The hotel was affordable, clean, safe, and had everything I needed for my 2 night stay. Continental breakfast was a nice touch, as well as the ice water and cookies in the front lobby. The staff was also polite and friendly. Will stay again! " [](https://expedia.ca/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Matlacha? ### What's there to see and do in Matlacha? ### What is a Matlacha spa hotel? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Cheap Hotels in Alden Pines ](https://www.expedia.ca/Alden-Pines-Hotels-Cheap-Hotels.0-0-d553248635976474573-tCheapHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Burnt Store ](https://www.expedia.ca/Burnt-Store-Cape-Coral-Hotels-Pet-Friendly-Hotel.0-n553248635976481229-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Florida ](https://www.expedia.ca/Destinations-In-Florida-Business-Hotel.0-0-d211-tBusinessHotel.Hotel-Filter-Destinations) - [Hotels & Resorts for Couples in Florida ](https://www.expedia.ca/Destinations-In-Florida-Couples-Resorts-Hotels.0-0-d211-tCouplesResortsHotels.Hotel-Filter-Destinations) - 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