
La Mesa Vacation Packages
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Save up to CA $1,096 when you book a flight and hotel together*
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Your La Mesa Vacation
Lock in a La Mesa vacation package that includes everything you need and nothing you don't. Good for gift and craft shops, dining and nightlife, think about staying in the neighborhood of Downtown San Diego. The Magnolia, Santee Lakes and Grossmont College are just a few of the attractions you'll want to explore during your trip to La Mesa. Browse Expedia's wide range of travel options and start organizing your perfect vacation to La Mesa today.
Top La Mesa Vacation Deals
Price found within the past 48 hours. Click for updated prices.

The Sofia Hotel
Downtown San Diego
per person
Oct 3 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEG) to San Diego (SAN)
8.4/10 Very Good! (1,488 reviews)
I reserved a room with 2 beds for my sister and I for a one night stay at Sophia hotel. When we arrived at 4PM our room was not ready and Ian gave me two waters and two chocolate candy bars and offered two rooms with one bed in place of the one room with two beds on the newly renovated floor right next to each other at no extra charge. It worked out perfectly as we had our own space.
Reviewed on Jul. 25, 2025

Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
per person
Sep 18 - Sep 24
found 13 hours ago
Roundtrip flight included
Toronto (YTO) to San Diego (SAN)
8.2/10 Very Good! (1,310 reviews)
this place was great except for 2 things... they don't take cash. AT ALL. and second, the jacuzzi tub in my room didn't work, and it seemed like they didn't care to fix it.
Reviewed on Jul. 25, 2025



Omni La Costa Resort & Spa Carlsbad
La Costa
per person
Sep 18 - Sep 24
found 13 hours ago
Roundtrip flight included
Toronto (YTO) to San Diego (SAN)
8.2/10 Very Good! (1,010 reviews)
We LOVE the Omni La Costa. Hosted my fiancés bachelor party as a golf weekend here and they had an amazing time. Zero complaints!
Reviewed on Jul. 25, 2025
La Mesa Hotel Deals

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is CA $150 per night from Aug 25 to Aug 26
CA $150
CA $172 total
Aug 25 - Aug 26
includes taxes & fees
8/10 Very Good! (1,901 reviews)
"The best part of this place was the fabulous pool. The staff was helpful and pleasant. The room was adequate, but it could use a facelift. Wall paper was warped towards the floor and our sliding door was stuck. Air conditioning worked very well, and the beds were comfortable. I will stay here again. ..."
Reviewed on Jul. 23, 2025

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is CA $197 per night from Jul 27 to Jul 28
CA $197
CA $268 total
Jul 27 - Jul 28
includes taxes & fees
8.2/10 Very Good! (5,776 reviews)
"Great location to midway & pier easy accessible to airport clean safe area Harbor Market two blocks away toward Santa Fe station. Hotel was nice bar downstairs closing a little early for me expect calling 3 times to get body wash for shower & no room food service otherwise ok would recommend."
Reviewed on Jul. 23, 2025

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is CA $270 per night from Jul 27 to Jul 28
CA $270
CA $387 total
Jul 27 - Jul 28
includes taxes & fees
9/10 Wonderful! (2,795 reviews)
"Needs updating. Shower mirrors show signs of wear and tear."
Reviewed on Jul. 24, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in La Mesa

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
CA $170
per adult
86% of travellers recommend

Crossing Borders: Tijuana Day Trip from San Diego
CA $127
per adult
100% of travellers recommend
Frequently asked questions
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.