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Check prices for these dates

Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29
In one month
Dec 11 - Dec 13
In two months
Jan 8 - Jan 10

Our top choices for La Mesa villas

An outdoor patio with a seating area, a grill, and a green wall.

1. Leyla| Pool/Spa|Downtown|Freeways|Beaches

Leyla| Pool/Spa|Downtown|Freeways|Beaches
Grant Hill
10.0 out of 10, Exceptional, (3 reviews)
"Everything was good, pool, spa, proximity to food and local frequent areas"
United States
Rob M.
The price is CA $174
CA $600 total
includes taxes & fees
Nov 16 - Nov 17
Leyla| Pool/Spa|Downtown|Freeways|Beaches
A landscaped garden with a central fountain, stone benches, and a paved walkway leading to a green lawn.

2. Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes

Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes
Jamul
9.6 out of 10, Exceptional, (60 reviews)
"Great stay"
United States
Carson M.
The price is CA $189
CA $593 total
includes taxes & fees
Nov 22 - Nov 23
Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes
An outdoor patio area with seating, a grill, and a decorative fence.

3. Bridge|Pool/Spa |Downtown|Freeways|Airport

Bridge|Pool/Spa |Downtown|Freeways|Airport
Grant Hill
10.0 out of 10, Exceptional, (3 reviews)
"The host was very helpful and accommodating. The place was excellent, and very close to downtown and the beaches that we wanted to visit.We will definitely stay at this place again next time we are in town."
United States
J C.
The price is CA $165
CA $589 total
includes taxes & fees
Nov 16 - Nov 17
Bridge|Pool/Spa |Downtown|Freeways|Airport
A two-story house with a garage, surrounded by palm trees and other vegetation.

4. Sleeps 50+ NEW Luxury Private Resort with Pool Golf Arcade Spa Playground Poker

Sleeps 50+ NEW Luxury Private Resort with Pool Golf Arcade Spa Playground Poker
Lakeside
10.0 out of 10, Exceptional, (17 reviews)
"Amazing property, host is very attentive, and overall a good experience !"
United States
Anthony S.
The price is CA $1,085
CA $2,205 total
includes taxes & fees
Nov 16 - Nov 17
Sleeps 50+ NEW Luxury Private Resort with Pool Golf Arcade Spa Playground Poker
A swimming pool with inflatable flamingos and a covered area with string lights.

5. Luxury•PickleBall•Golf•Pool•HotTub•Grill•Arcades•6 TV’s•Playground• .5 Acre

Luxury•PickleBall•Golf•Pool•HotTub•Grill•Arcades•6 TV’s•Playground• .5 Acre
El Cajon
10.0 out of 10, Exceptional, (10 reviews)
"This place is an awesome vacation spot! The home is comfortable and the outdoor area is spectacular…even for a large group! Alvin is incredible to work with!"
United States
Sherri B.
The price is CA $692
CA $1,753 total
includes taxes & fees
Dec 8 - Dec 9
Luxury•PickleBall•Golf•Pool•HotTub•Grill•Arcades•6 TV’s•Playground• .5 Acre
An outdoor pool area with a slide, seating, and umbrellas.

6. Resort-Style Villa with Pool & Spa

Resort-Style Villa with Pool & Spa
Rancho Bernardo
The price is CA $313
CA $658 total
includes taxes & fees
Nov 24 - Nov 25
Resort-Style Villa with Pool & Spa
A modern house with a front entrance, a number '2552' on the wall, and a staircase leading up to the door.

7. 5-Units/26 guests/Heated Pool Option/Spa

5-Units/26 guests/Heated Pool Option/Spa
Grant Hill
The price is CA $1,043
CA $2,882 total
includes taxes & fees
Nov 16 - Nov 17
5-Units/26 guests/Heated Pool Option/Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

See all hotels in La Mesa
A sunset over a mountainous landscape with scattered clouds.

Top reviews in La Mesa

A hotel with a pool, outdoor seating, and palm trees.
Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU
Mid-City

10/10 Excellent

Exceeded our expectations. It was clean, quiet and staff were awesome. Would definitely return.
Canada
Sandra
Reviewed June 14, 2026
Lamplighter Inn & Suites at SDSU

Frequently Asked Questions

How much do villas in La Mesa cost?

You'll pay between CA $165 and CA $1,084 per night for villas in La Mesa. No matter your budget, an awesome stay is only a click or two away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

How many villas are there in La Mesa?

Use up your vacation days and choose from villas in La Mesa. For a family adventure, a getaway with friends or anything in between, Expedia can help you find the ideal space in just a click or two.

Why book your villa in La Mesa with Expedia?

Expedia makes it a cinch to find your dream villa in La Mesa. Traveling with the kids? Take advantage of our filters to search for stays with perks like a pool. If you're on a budget, choose how much you want to spend and your preferred star rating. We'll help you find the right place that suits your style and taste.

How can I find cheap villas in La Mesa?

Expedia can help you narrow your search for cheap villas in La Mesa. Use our filter tool to select budget, amenities and star rating to refine your search and find an ideal stay in a few quick keystrokes.

What is there to do near my villa in La Mesa?

If you're eager to explore the best of La Mesa, be sure to visit Mount Helix Park. It's a hit with locals and travelers alike.

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