Florida Keys National Marine Sanctuary Tours and Activities
Visit Florida Keys National Marine Sanctuary
Plan a trip to see Florida Keys National Marine Sanctuary
Price found within the past 48 hours. Click for updated prices.
Lighthouse Hotel - Key West Historic Inns
Old Town Key West
Price was CA $857, price is now CA $505 per person
CA $505
per person
Sep 23 - Sep 26
found 7 hours ago
Roundtrip flight included
Detroit (DTW) to Key West (EYW)
9/10 Wonderful! (775 reviews)
it’s a great location but quiet. Love the free breakfast, pool and rooms! staff was great too!
Reviewed on Aug. 23, 2025
Ella's Cottages - Key West Historic Inns
Old Town Key West
Price was CA $2,966, price is now CA $1,867 per person
CA $1,867
per person
Nov 16 - Nov 22
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Key West (EYW)
9.4/10 Exceptional! (366 reviews)
everything was easy and staff was very helpful!
Reviewed on Aug. 18, 2025
Pier House Resort & Spa
Key West Historic District
Price was CA $3,192, price is now CA $2,107 per person
CA $2,107
per person
Nov 16 - Nov 22
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Key West (EYW)
9/10 Wonderful! (1,014 reviews)
The bathroom was very nice. The rest of the room was just ok. The common hallway had trash on the floor for the entire weekend. Nobody swept the floor at all. For the money you pay there are better hotels.
Reviewed on Aug. 18, 2025
Tours & day trips
See all 158 activities
Day trip to Paradise from Miami: Key West Tour with Snorkelling, Open bar
Activity duration is 16 hours and 30 minutes
7.8 out of 10 with 15 reviews
History & culture
See all 54 activities
Key West Day Trip & Glass Bottom-Boat Tour from Miami
Activity duration is 12 hours
5.0 out of 10 with 27 reviews
Free cancellation available
Wildlife & nature
See all 48 activities
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Activity duration is 3 hours
9.2 out of 10 with 129 reviews
Free cancellation available
Private & custom tours
See all 36 activities
Dry Tortugas National Park Day Trip by Luxury Boat: Axopar 37 XC
Activity duration is 8 hours
Free cancellation available
Adventure & outdoor
See all 17 activities
Key West Half-Day Fishing Charter
Activity duration is 5 hours
9.2 out of 10 with 14 reviews
Free cancellation available
Popular places to visit
Florida Keys Eco - Discovery Center
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
Fort Zachary Taylor Historic State Park
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
Truman Beach
Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
Jackson Square
You can learn about the history of Key West with a stop at Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.
Harry S. Truman Little White House
Visit the winter home of President Harry S. Truman to see where some of America’s most important post-war decisions were made.
Key West Lighthouse and Keeper's Quarters Museum
Climb to the top of this historic lighthouse for unparalleled photo opportunities and then visit the former home of Key West’s lighthouse keepers.
Best Lodging Options Near Florida Keys National Marine Sanctuary
Check availability on hotels close to Florida Keys National Marine Sanctuary
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Hyatt Centric Key West Resort and Spa
601 Front St, Key West, FL
Pier House Resort & Spa
1 Duval St, Key West, FL
The Southernmost Inn - Adults Only
525 United Street, Key West, FL
La Concha Key West, Autograph Collection
430 Duval St, Key West, FL
Casa Marina Key West, Curio Collection by Hilton
1500 Reynolds Street, Key West, FL
Opal Key Resort & Marina, Key West
245 Front Street, Key West, FL
Lighthouse Hotel - Key West Historic Inns
902 Whitehead St, Key West, FL
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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