Title: The 10 Best Hotels Near Florida Keys National Marine Sanctuary, Key West from CA $229 | Expedia.ca

[Key West Travel Guide](https://expedia.ca/Key-West.dx1187)[Flights to Key West](https://expedia.ca/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)[Things to do in Key West](https://expedia.ca/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)[Florida Keys National Marine Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Florida-Keys-National-Marine-Sanctuary.d6163838.Car-Rental-Guide)[Florida Keys National Marine Sanctuary Vacations](https://expedia.ca/Florida-Keys-National-Marine-Sanctuary-Key-West.d6163838.Vacation-Attraction)

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# Find hotels near Florida Keys National Marine Sanctuary, Key West from CA $229

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## Check prices for these dates

Tonight

[Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=6163838&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=6163838&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6163838&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6163838&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Florida Keys National Marine Sanctuary hotels

![Queen Deluxe ADA](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/3d7c7063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mini-refrigerator](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/bc9a86c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/1ae9d542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/0bfa8d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Almond Tree Inn Hotel - Adults Only

[](https://www.expedia.ca/Key-West-Hotels-Almond-Tree-Inn.h809031.Hotel-Information)

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

10/10

Exceptional

(1001)

"Very nice & peaceful with a wonderful staff. Our second time staying here"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sandra

CA $311

CA $350 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-Almond-Tree-Inn.h809031.Hotel-Information)

![King Room D | Balcony](https://images.trvl-media.com/lodging/38000000/37910000/37900100/37900084/350337ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/38000000/37910000/37900100/37900084/6492356c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![King Room B | View from room](https://images.trvl-media.com/lodging/38000000/37910000/37900100/37900084/4d0697b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Single B | View from room](https://images.trvl-media.com/lodging/38000000/37910000/37900100/37900084/77670d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Simonton Court Historic Inn & Cottages

[](https://www.expedia.ca/Key-West-Hotels-Simonton-Court-Historic-Inn-Guesthouse.h37900084.Hotel-Information)

Historic Seaport, 1 km from Florida Keys National Marine Sanctuary

9.8/10

Exceptional

(878)

"The staff was really nice"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

doug

CA $203

CA $229 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Key-West-Hotels-Simonton-Court-Historic-Inn-Guesthouse.h37900084.Hotel-Information)

![Carriage House | Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/20800/20796/424c57d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Eyebrow Cottage](https://images.trvl-media.com/lodging/1000000/30000/20800/20796/c1cafba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20800/20796/10c614cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Historic | Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/20800/20796/9b9f5a18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Gardens Hotel

[](https://www.expedia.ca/Key-West-Hotels-The-Gardens-Hotel.h20796.Hotel-Information)

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

9.8/10

Exceptional

(1001)

"Amazing hotel, the perfect Key West vibe. Clean rooms, delicious breakfast. We will come back again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isis

CA $463

CA $521 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-The-Gardens-Hotel.h20796.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/5e9e36b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/4d0009a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sundeck](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/a23eab61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/e63ab6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Orchid Key Inn - Adults Only

[](https://www.expedia.ca/Key-West-Hotels-Orchid-Key-Inn.h809032.Hotel-Information)

Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary

9.8/10

Exceptional

(1002)

"Staff awesome, good breakfast great location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carin helen

CA $292

CA $329 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Key-West-Hotels-Orchid-Key-Inn.h809032.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/d2b2f582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![414 Balcony Deluxe](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/aac6a7e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 outdoor pools](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/0c033c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/12655222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Marquesa Hotel

[](https://www.expedia.ca/Key-West-Hotels-The-Marquesa-Hotel.h889862.Hotel-Information)

Historic Seaport, 1 km from Florida Keys National Marine Sanctuary

9.8/10

Exceptional

(1001)

"Perfect place to stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paulette

CA $591

CA $742 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-The-Marquesa-Hotel.h889862.Hotel-Information)

![Deluxe Suite, 1 King Bed, Private Pool | View from room](https://images.trvl-media.com/lodging/17000000/16400000/16396000/16395930/b744fec6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/17000000/16400000/16396000/16395930/44a19a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Suite, 1 King Bed, Private Pool | View from room](https://images.trvl-media.com/lodging/17000000/16400000/16396000/16395930/320d50ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16400000/16396000/16395930/d854c1ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### H2O Suites - Adults Only

[](https://www.expedia.ca/Key-West-Hotels-H2O-Suites-Adults-Only.h16395930.Hotel-Information)

Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary

9.8/10

Exceptional

(581)

"Great place!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joel

CA $426

CA $572 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-H2O-Suites-Adults-Only.h16395930.Hotel-Information)

![11 Gecko's Garden - Adults Only](https://images.trvl-media.com/lodging/10000000/9690000/9681100/9681053/5a952061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9690000/9681100/9681053/a7d26b15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/10000000/9690000/9681100/9681053/bbaba58e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Poinciana Patio, Pool View, Patio - Adult Only | Terrace/patio](https://images.trvl-media.com/lodging/10000000/9690000/9681100/9681053/a07e6903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tropical Inn

[](https://www.expedia.ca/Key-West-Hotels-Tropical-Inn.h9681053.Hotel-Information)

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

9.6/10

Exceptional

(363)

"The place was excellent and the service amazing "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janae

CA $236

CA $300 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Key-West-Hotels-Tropical-Inn.h9681053.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/900000/894100/894030/dc763054.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/900000/894100/894030/14ad35b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/900000/894100/894030/eb0b0d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/900000/894100/894030/76b4e71a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Silver Palms Inn

[](https://www.expedia.ca/Key-West-Hotels-Silver-Palms-Inn.h894030.Hotel-Information)

Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary

9.4/10

Exceptional

(1024)

"We had a wonderful stay and it was a convenient location for all the activities along Duval Street. The room was clean & comfortable with a great breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susanne

CA $185

CA $301 total

includes taxes & fees

Dec 18 - Dec 19

[](https://www.expedia.ca/Key-West-Hotels-Silver-Palms-Inn.h894030.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/f2c5f58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/137c65ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/acfeb5a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/3ac97dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Opal Key Resort & Marina, Key West

[](https://www.expedia.ca/Key-West-Hotels-Opal-Key-Resort-Marina.h17442701.Hotel-Information)

Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary

9.2/10

Wonderful

(1023)

"Our stay was great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

CA $384

CA $487 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-Opal-Key-Resort-Marina.h17442701.Hotel-Information)

![Cottage, 2 Bedrooms (Royal Poinciana) | Terrace/patio](https://images.trvl-media.com/lodging/4000000/3930000/3924900/3924835/069168f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3930000/3924900/3924835/894f1440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3930000/3924900/3924835/8a300017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite](https://images.trvl-media.com/lodging/4000000/3930000/3924900/3924835/7c366980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Paradise Inn Key West - Adults Only

[](https://www.expedia.ca/Key-West-Hotels-Paradise-Inn-Key-West-Adults-Only.h3924835.Hotel-Information)

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

9.2/10

Wonderful

(1003)

"Cozy place right near everything "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joseph

[](https://www.expedia.ca/Key-West-Hotels-Paradise-Inn-Key-West-Adults-Only.h3924835.Hotel-Information)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/a299c4a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/05980c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/50962e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Partial Harbor View](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/66a642ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ocean Key Resort - A Noble House Resort

[](https://www.expedia.ca/Key-West-Hotels-Ocean-Key-Resort-A-Noble-House-Resort.h16682.Hotel-Information)

Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary

9.2/10

Wonderful

(1004)

"Great stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sarit

CA $577

CA $756 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Key-West-Hotels-Ocean-Key-Resort-A-Noble-House-Resort.h16682.Hotel-Information)

![3 outdoor pools, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/530000/529700/529611/7cf7d263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Truman)](https://images.trvl-media.com/lodging/1000000/530000/529700/529611/33f2b657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Winslet) | Exterior](https://images.trvl-media.com/lodging/1000000/530000/529700/529611/f458d20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/530000/529700/529611/414fe812.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Winslow's Bungalows - Key West Historic Inns

[](https://www.expedia.ca/Key-West-Hotels-Kimpton-Winslows-Bungalows.h529611.Hotel-Information)

Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary

9.2/10

Wonderful

(1073)

"Beautiful property, nice clean bungalows and great staff!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $315

CA $424 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-Kimpton-Winslows-Bungalows.h529611.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3853/aebf156d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach nearby, beach towels](https://images.trvl-media.com/lodging/1000000/10000/3900/3853/e0f768ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/10000/3900/3853/c8d74747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 restaurants, breakfast served, Caribbean cuisine](https://images.trvl-media.com/lodging/1000000/10000/3900/3853/a3b28d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Concha Key West, Autograph Collection

[](https://www.expedia.ca/Key-West-Hotels-Crowne-Plaza-Key-West-La-Concha.h3853.Hotel-Information)

Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary

9.0/10

Wonderful

(285)

"Hotel staff was amazing. Room was spotless! Excellent place to stay! Will definitely stay here again in the future! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tracy

CA $315

CA $401 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-Crowne-Plaza-Key-West-La-Concha.h3853.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/04396af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/705cf1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/ee4555f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/c435c8cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Heron House - Adult Only

[](https://www.expedia.ca/Key-West-Hotels-Heron-House-Adult-Only.h57730.Hotel-Information)

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

9.0/10

Wonderful

(1136)

"Loved the setup of the hotel and great location! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rachel

CA $176

CA $244 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Key-West-Hotels-Heron-House-Adult-Only.h57730.Hotel-Information)

![Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1180000/1171100/1171079/2155599f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/2000000/1180000/1171100/1171079/e5e2da29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Hemingway)](https://images.trvl-media.com/lodging/2000000/1180000/1171100/1171079/70163bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1180000/1171100/1171079/b1b0732e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lighthouse Hotel - Key West Historic Inns

[](https://www.expedia.ca/Key-West-Hotels-Kimpton-Lighthouse-Hotel.h1171079.Hotel-Information)

Bahama Village, 0.6 km from Florida Keys National Marine Sanctuary

9.0/10

Wonderful

(847)

"Great location. Near great food and entertainment."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

CA $299

CA $406 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Key-West-Hotels-Kimpton-Lighthouse-Hotel.h1171079.Hotel-Information)

![Sundeck](https://images.trvl-media.com/lodging/6000000/5710000/5703000/5702955/0d04a670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/6000000/5710000/5703000/5702955/e9dfd75a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Room w/porch, 1 King Bed - Adult Exclusive | View from room](https://images.trvl-media.com/lodging/6000000/5710000/5703000/5702955/c7a1cb1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, individually decorated](https://images.trvl-media.com/lodging/6000000/5710000/5703000/5702955/f64c5358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seascape Tropical Inn - Adult Exclusive

[](https://www.expedia.ca/Key-West-Hotels-Seascape-Tropical-Inn.h5702955.Hotel-Information)

Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary

9.0/10

Wonderful

(404)

"Room was spotless and the front desk was excellent. I would stay with them again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dave

CA $216

CA $313 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-Seascape-Tropical-Inn.h5702955.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1000/901/0b72a249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/1000/901/09ed2e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine, ocean views ](https://images.trvl-media.com/lodging/1000000/10000/1000/901/ea2f021f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/1000/901/f89b6e1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Centric Key West Resort and Spa

[](https://www.expedia.ca/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information)

Historic Seaport, 1.3 km from Florida Keys National Marine Sanctuary

9.0/10

Wonderful

(1009)

"Staff was courteous and the location is perfect for a weekend in Key West."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

TIMOTHY

CA $391

CA $530 total

includes taxes & fees

Dec 18 - Dec 19

[](https://www.expedia.ca/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information)

![Studio Suite | Living area](https://images.trvl-media.com/lodging/2000000/1710000/1709300/1709243/365028d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite | Living area](https://images.trvl-media.com/lodging/2000000/1710000/1709300/1709243/7143a78a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1710000/1709300/1709243/df1f6f71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1710000/1709300/1709243/9cd0d2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Eden House

[](https://www.expedia.ca/Key-West-Hotels-Eden-House.h1709243.Hotel-Information)

Historic Seaport, 1.6 km from Florida Keys National Marine Sanctuary

9.0/10

Wonderful

(1004)

"Its a cozy place and very pleasant staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan Francisco Garcia

CA $427

CA $538 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/Key-West-Hotels-Eden-House.h1709243.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/98bddc65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/cf7f237d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/56dfeed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/a5da01ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Cabana Inn Key West - Adults Only

[](https://www.expedia.ca/Key-West-Hotels-The-Cabana-Inn-Key-West-Adults-Only.h6576609.Hotel-Information)

Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary

8.8/10

Excellent

(1002)

"The staff was welcoming, friendly and helpful. The resort itself was well kept."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin

CA $179

CA $264 total

includes taxes & fees

Dec 18 - Dec 19

[](https://www.expedia.ca/Key-West-Hotels-The-Cabana-Inn-Key-West-Adults-Only.h6576609.Hotel-Information)

![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/026f10af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/b4576547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/4eda9d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/69828d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Southernmost Beach Resort and Guesthouses

[](https://www.expedia.ca/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information)

Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary

8.8/10

Excellent

(2935)

"Great stay with an actual beach which is rare in Key West. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

CA $259

CA $392 total

includes taxes & fees

Dec 18 - Dec 19

[](https://www.expedia.ca/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-29&endDate=2025-12-30&regionId=6163838&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Florida Keys National Marine Sanctuary Hotel Reviews

![Southernmost Beach Resort and Guesthouses](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/026f10af_y.jpg)

### Southernmost Beach Resort and Guesthouses

10/10 Excellent

"Beach and pool - bar, music and great staff"

[](https://expedia.ca/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information)

![Pier House Resort & Spa](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/c9267f77_y.jpg)

### Pier House Resort & Spa

10/10 Excellent

"Clean room, great amenities, very nice staff and close by foot to restaurants and stores."

[](https://expedia.ca/Key-West-Hotels-Pier-House-Resort-Spa.h19307.Hotel-Information)

![Duval House](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/d8706fe9_y.jpg)

### Duval House

10/10 Excellent

"The garden area was fabulous "

[](https://expedia.ca/Key-West-Hotels-Duval-House.h900423.Hotel-Information)

![Coco Plum Inn](https://images.trvl-media.com/lodging/3000000/2240000/2232000/2231933/a17d99e1_y.jpg)

### Coco Plum Inn

10/10 Excellent

"Amazing location, staff was courteous, and the vibes were great. "

[](https://expedia.ca/Key-West-Hotels-Coco-Plum-Inn.h2231933.Hotel-Information)

![La Concha Key West, Autograph Collection](https://images.trvl-media.com/lodging/1000000/10000/3900/3853/aebf156d_y.jpg)

### La Concha Key West, Autograph Collection

10/10 Excellent

"My husband and I enjoyed our stay at the hotel tremendously - everything was excellent! Location, cleanliness, pool, food, bedding, friendly staff, hotel decor, pleasant ambiance. Highly recommend this hotel to the guests who want to experience upscale services and hospitality of old Florida"

[](https://expedia.ca/Key-West-Hotels-Crowne-Plaza-Key-West-La-Concha.h3853.Hotel-Information)

![Opal Key Resort & Marina, Key West](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/f2c5f58d_y.jpg)

### Opal Key Resort & Marina, Key West

10/10 Excellent

"Wonderful little resort. Bartender Mike at Opals - Lolita’s outdoor bar(s) is the BEST…."

[](https://expedia.ca/Key-West-Hotels-Opal-Key-Resort-Marina.h17442701.Hotel-Information)

![Winslow's Bungalows - Key West Historic Inns](https://images.trvl-media.com/lodging/1000000/530000/529700/529611/7cf7d263_y.jpg)

### Winslow's Bungalows - Key West Historic Inns

10/10 Excellent

"Quaint hotel with beautiful grounds. Close to everything yet far away enough away from Duvall. Clean and comfortable rooms"

[](https://expedia.ca/Key-West-Hotels-Kimpton-Winslows-Bungalows.h529611.Hotel-Information)

![Amsterdam's Curry Mansion Inn](https://images.trvl-media.com/lodging/1000000/10000/300/217/c6778dc1_y.jpg)

### Amsterdam's Curry Mansion Inn

10/10 Excellent

"Clean room "

[](https://expedia.ca/Key-West-Hotels-Amsterdams-Curry-Mansion-Inn.h217.Hotel-Information)

![Heron House - Adult Only](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/04396af1_y.jpg)

### Heron House - Adult Only

10/10 Excellent

"Yes"

[](https://expedia.ca/Key-West-Hotels-Heron-House-Adult-Only.h57730.Hotel-Information)

## Hotels near other Florida Keys National Marine Sanctuary attractions

![Florida Keys Eco - Discovery Center which includes interior views](https://images.trvl-media.com/place/6069247/474d6adf-b186-47b4-a027-1e3a6d32dc25.jpg)

### Florida Keys Eco - Discovery Center

4.3/5 (128 reviews)

Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6069247)

![Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com](https://images.trvl-media.com/place/6069245/fc7525f8-453d-41c7-bc20-e32416890fb1.jpg)

### Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)

The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6069245)

![](https://images.trvl-media.com/place/1187/1201d89a-fb81-4e18-91c2-0cc24a30129f.jpg)

### Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635983989797)

![Jackson Square showing a garden](https://images.trvl-media.com/place/6249254/072a05e3-dca5-4abe-9f06-4e35b7787615.jpg)

### Jackson Square

You can learn about the history of Key West with a stop at Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6249254)

![Harry S. Truman Little White House showing interior views and a house](https://images.trvl-media.com/place/6068605/08afa45c-9c33-4a64-914f-76a597bb6364.jpg)

### Harry S. Truman Little White House

4.4/5 (983 reviews)

Visit the winter home of President Harry S. Truman to see where some of America’s most important post-war decisions were made.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6068605)

![Key West Lighthouse and Keeper\'s Quarters Museum which includes views, a coastal town and landscape views](https://images.trvl-media.com/place/501383/b0caa24d-4abc-4245-a009-f22e55fd5e86.jpg)

### Key West Lighthouse and Keeper's Quarters Museum

4.2/5 (543 reviews)

Climb to the top of this historic lighthouse for unparalleled photo opportunities and then visit the former home of Key West’s lighthouse keepers.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=501383)

### USCGC Ingham Maritime Museum

You can spend an afternoon exploring the galleries in USCGC Ingham Maritime Museum during your trip to Key West. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=801219351206326272)

### We Cycle Key West

You can search for that perfect souvenir at We Cycle Key West during your trip to Key West. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=827848417466060800)

## Frequently asked questions

### What's the area like around Florida Keys National Marine Sanctuary?

### Where is the best place to stay close to Florida Keys National Marine Sanctuary?

### How many hotels will I be able to find near Florida Keys National Marine Sanctuary?

### If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?

### What can I see and do near Florida Keys National Marine Sanctuary?

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- [Hotels near South Beach ](https://www.expedia.ca/South-Beach-Hotels.0-l6246827-0.Travel-Guide-Filter-Hotels)
- [Hotels near Southernmost Point ](https://www.expedia.ca/Southernmost-Point-Hotels.0-l501380-0.Travel-Guide-Filter-Hotels)
- [Hotels near Studios of Key West ](https://www.expedia.ca/Studios-Of-Key-West-Hotels.0-l553248621532652634-0.Travel-Guide-Filter-Hotels)
- [Sunset Key Hotels ](https://www.expedia.ca/Sunset-Key-Key-West-Hotels.0-n553248635976481798-0.Travel-Guide-Filter-Hotels)
- [Adults Only Resorts & in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-Adults-Only-Resorts.0-n553248635976473207-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
- [All Inclusive Resorts and in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-All-Inclusive-Hotel.0-n553248635976473207-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
- [Beach Hotel Hotels in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-Beach-Hotel.0-n553248635976473207-0-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-Cheap-Hotels.0-n553248635976473207-0-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Hotels with Early Check-in in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-Hotel-With-Early-Check-In.0-n553248635976473207-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)
- [Hotels with Free Parking in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-Hotels-With-Free-Parking.0-n553248635976473207-0-tHotelswithFreeParking.Travel-Guide-Filter-Hotels)
- [Lgbt Friendly Hotels in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-LGBT-Friendly-Hotel.0-n553248635976473207-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
- [Oceanfront Hotels in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-Oceanfront-Hotels.0-n553248635976473207-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
- [Romantic Hotels in Truman Annex ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels-Romantic-Hotel.0-n553248635976473207-0-tRomanticHotel.Travel-Guide-Filter-Hotels)
- [Truman Annex Hotels ](https://www.expedia.ca/Truman-Annex-Key-West-Hotels.0-n553248635976473207-0.Travel-Guide-Filter-Hotels)
- [Uptown - Upper Duval Hotels ](https://www.expedia.ca/Uptown-Upper-Duval-Key-West-Hotels.0-n553248635976473524-0.Travel-Guide-Filter-Hotels)

- [Flights to Key West ](https://www.expedia.ca/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)
- [Flights from Williston to Key West ](https://www.expedia.ca/lp/flights/1636/1187/williston-to-key-west)
- [Flights from Detroit to Key West ](https://www.expedia.ca/lp/flights/178255/1187/detroit-to-key-west)
- [Flights from Ottawa to Key West ](https://www.expedia.ca/lp/flights/178296/1187/ottawa-to-key-west)
- [Flights from Toronto to Key West ](https://www.expedia.ca/lp/flights/178314/1187/toronto-to-key-west)
- [Flights from Hamilton to Key West ](https://www.expedia.ca/lp/flights/3963/1187/hamilton-to-key-west)
- [Flights from Winnipeg to Key West ](https://www.expedia.ca/lp/flights/6141041/1187/winnipeg-to-key-west)

- [Duval Street ](https://www.expedia.ca/Duval-Street-Key-West-Historic-District.d6068616.Vacation-Attraction)
- [Florida Keys Eco - Discovery Center ](https://www.expedia.ca/Florida-Keys-Eco-Discovery-Center-Old-Town-Key-West.d6069247.Vacation-Attraction)
- [Fort Zachary Taylor Historic State Park ](https://www.expedia.ca/Fort-Zachary-Taylor-Historic-State-Park-Key-West.d6069245.Vacation-Attraction)
- [Harry S. Truman Little White House ](https://www.expedia.ca/Harry-S-Truman-Little-White-House-Old-Town-Key-West.d6068605.Vacation-Attraction)
- [Visit Bahama Village ](https://www.expedia.ca/Key-West-Bahama-Village.dx553248621533115696)
- [Visit Downtown Key West ](https://www.expedia.ca/Key-West-Downtown-Key-West.dx553248635976470405)
- [Key West Lighthouse and Keeper's Quarters Museum ](https://www.expedia.ca/Key-West-Lighthouse-And-Keepers-Quarters-Museum-Old-Town-Key-West.d501383.Vacation-Attraction)
- [Key West Vacations ](https://www.expedia.ca/Key-West.d1187.Destination-Travel-Guides)
- [Visit Key West ](https://www.expedia.ca/Key-West.dx1187)
- [All inclusive Vacation Packages Key West ](https://www.expedia.ca/lp/theme-vacations/all-inclusive-vacations/1187/Key-West)

- [Car rental Key West ](https://www.expedia.ca/Car-Rentals-In-Key-West.d1187.Car-Rental-Guide)
- [Pickup Car Rentals in Key West ](https://www.expedia.ca/Pickup-Car-Rentals-In-Key-West.d1187-tPickup.Car-Rental-Guide-Class)

- [Key West Vacation Rentals ](https://www.expedia.ca/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)

- [Things to do in Key West ](https://www.expedia.ca/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)