A coastal landscape with rocky cliffs, green hills, and a clear blue sea.

5 Stars Hotels in Mediterranean Region, from CA $120

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Check availability on Mediterranean Region 5 Star Hotels

Tonight
Oct 9 - Oct 10
Tomorrow
Oct 10 - Oct 11
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Mediterranean Region 5-star hotels

A Gothic cathedral with multiple spires, surrounded by urban buildings and a clear sky.
A restaurant with large windows, wooden chairs, and tables.
A terrace with white wicker chairs and tables, overlooking a historic cathedral with intricate Gothic architecture.
A person holding two champagne flutes with a historic building in the background.

1. Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
Downtown Barcelona
United Kingdom
Andrew
CA $351
CA $429 total
includes taxes & fees
Nov 6 - Nov 7
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
A modern indoor pool area with a geometric wall design, a reception desk, and lounge seating.
A food preparation area with hanging meats, a variety of cheeses, and a person in a white coat.
A spa area with green cushioned seating, a large window, and a view of the outdoors.
A building with the name 'PHILOSOFIA' on the facade, large glass windows, and potted plants in the foreground.

2. Grand Hyatt Barcelona

Grand Hyatt Barcelona
Les Corts
United States
YESNEIDY
CA $242
CA $308 total
includes taxes & fees
Nov 6 - Nov 7
Grand Hyatt Barcelona
A modern restaurant with high ceilings, large windows, and a view of the city.
A modern indoor pool area with a glass barrier, marble flooring, and a seating area with wooden panels and cushions.
A modern restaurant with a bar area, large windows, and hanging plants.
A modern lobby with a reception desk, large windows, and a unique chandelier.

3. Grand Hyatt Athens

Grand Hyatt Athens
Neos Kosmos
United States
Kenneth
CA $142
CA $167 total
includes taxes & fees
Nov 8 - Nov 9
Grand Hyatt Athens
An indoor gym with cardio machines, a large exercise ball, and a view of palm trees and buildings through large windows.
A spacious bedroom with a large bed, two bedside tables, and a view of the ocean.
A restaurant with a long table set for dining, multiple hanging pendant lights, and red patterned chairs.
Beach/ocean view

4. W Barcelona

W Barcelona
Barceloneta
United States
Melissa
CA $529
CA $624 total
includes taxes & fees
Oct 22 - Oct 23
W Barcelona
A modern building with a glass facade, outdoor seating area, and a staircase leading to the entrance.
A restaurant with a bar area, booths, and a view of the outdoors.
An indoor swimming pool with lounge chairs and a view of mountains.
Bar (on property)

5. Sofitel Athens Airport

Sofitel Athens Airport
Spata-Artemida
United States
Jonell
CA $451
CA $519 total
includes taxes & fees
Nov 4 - Nov 5
Sofitel Athens Airport
Meeting facility
A swimming pool with lounge chairs and umbrellas, surrounded by greenery and a tiered garden.
A modern hotel with a symmetrical facade, multiple floors, and a prominent entrance with a canopy.
A modern living room with a view of a cityscape and a historic building.

6. Athenaeum InterContinental by IHG

Athenaeum InterContinental by IHG
Neos Kosmos
Canada
Marcelo
CA $234
CA $273 total
includes taxes & fees
Nov 8 - Nov 9
Athenaeum InterContinental by IHG
A courtyard with wicker furniture, potted plants, and a glass door entrance.
A spacious living room with a large sofa set, a coffee table, and a fireplace.
A spa area with a hot tub, two wooden lounge chairs, and a tiled wall with a blue mosaic pattern.
A multi-story hotel with a modern facade, featuring balconies with green railings. The hotel's name is displayed prominently above the entrance.

7. Hotel Real Palacio

Hotel Real Palacio
Lisbon City Center
United States
Cheryl
CA $170
CA $193 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Real Palacio
A bathtub with a city view, wooden walls, and a slatted ceiling.
A rooftop terrace with wooden flooring, cushioned seating, and tables.
A restaurant with tables set for dining, featuring a city view through large windows.
A modern interior with a curved staircase, seating area, and large windows offering a city view.

8. Nobu Hotel Barcelona

Nobu Hotel Barcelona
Sants-Montjuïc
United States
Jacqueline J
CA $358
CA $436 total
includes taxes & fees
Nov 8 - Nov 9
Nobu Hotel Barcelona
A restaurant with a curved seating area, a view of the sea, and potted plants.
A rooftop pool area with yellow lounge chairs and a view of the sunset over the ocean.
A bar area with a marble countertop, multiple shelves of liquor bottles, and bar stools.
A modern bar area with a wooden ceiling, a bar counter, and a wall of circular mirrors.

9. Ace Hotel & Swim Club Athens

Ace Hotel & Swim Club Athens
Glyfada
Ireland
Michaela
CA $233
CA $271 total
includes taxes & fees
Nov 9 - Nov 10
Ace Hotel & Swim Club Athens
An outdoor dining area with tables and chairs, overlooking a historic building.
A rooftop terrace with a hot tub, lounge chairs, and a pergola.
A luxurious hallway with marble walls and floors, leading to a well-lit room with furniture and plants.
A spacious lobby with a high ceiling, large columns, and a skylight.

10. Divani Palace Acropolis

Divani Palace Acropolis
Athens City Centre
United States
Vanik
CA $218
CA $254 total
includes taxes & fees
Nov 8 - Nov 9
Divani Palace Acropolis
A geodesic dome interior with seating and a view of a cityscape through large windows.
A spacious lobby with a modern design, featuring a large seating area, a coffee machine, and a view of a river.
A modern building with a glass facade, a pool area with sun loungers and umbrellas, and a view of the pool.
A modern living room with a sectional sofa, armchairs, and a coffee table.

11. Hyatt Regency Barcelona Tower

Hyatt Regency Barcelona Tower
Bellvitge
United States
Rakesh
CA $215
CA $266 total
includes taxes & fees
Nov 8 - Nov 9
Hyatt Regency Barcelona Tower
A water park with multiple slides and pools, surrounded by trees and a view of the sea.
A hotel room with two beds, a desk, a TV, and a window with curtains.
A hotel room with a large bed, a desk, a chair, and a balcony with a view of greenery.
A resort with a swimming pool, outdoor seating areas, and a prominent tower.

12. Swandor Hotels & Resort Topkapi Palace - All Inclusive

Swandor Hotels & Resort Topkapi Palace - All Inclusive
Lara
United States
Aline
CA $280
CA $316 total
includes taxes & fees
Oct 24 - Oct 25
Swandor Hotels & Resort Topkapi Palace - All Inclusive
A modern restaurant with a central round table, surrounded by chairs, and a variety of plants and greenery.
An indoor swimming pool with wooden beams, lounge chairs, and potted plants.
A lobby with a central round table surrounded by armchairs, a patterned floor, and a modern ceiling design.
A bar area with a wooden ceiling, hanging lights, and a variety of bottles on shelves.

13. Corinthia Lisbon

Corinthia Lisbon
Lisbon City Center
United Kingdom
Patrick Kwame
CA $364
CA $399 total
includes taxes & fees
Oct 26 - Oct 27
Corinthia Lisbon
A modern hotel with a rooftop terrace, a swimming pool, and lush greenery.
A modern lobby with a bar area, seating, and plants.
A luxurious interior with a grand chandelier, a marble-tiled floor, and a central island with various items.
An outdoor seating area with tables and chairs, a large tree, and a covered section with arches.

14. Conrad Athens The Ilisian

Conrad Athens The Ilisian
Athens City Centre
United States
Abdulla
CA $572
CA $675 total
includes taxes & fees
Oct 25 - Oct 26
Conrad Athens The Ilisian
An indoor swimming pool with clear glass walls, potted plants, and a view of the cityscape.
The entrance of Barceló Torre de Madrid with glass doors, potted plants, and a sign for SOMOS restaurant and GAMA bar.
A spacious lobby with a modern blue sofa, yellow armchairs, and a unique striped sculpture.
A hotel room with a large bed, green pillows, a green throw blanket, a view of a cityscape through large windows, and a decorative mirror with geometric patterns.

15. Barceló Torre de Madrid

Barceló Torre de Madrid
Madrid Centro
United States
Alfred
CA $364
CA $401 total
includes taxes & fees
Nov 1 - Nov 2
Barceló Torre de Madrid
A swimming pool with a clear blue water surface, surrounded by palm trees and a building with multiple balconies.
A lobby with a central staircase, ornate columns, and seating areas.
A room with a round table, two chairs, a sofa, and a view of a tower.
A multi-story hotel with outdoor seating areas, palm trees, and a tiled floor.

16. La Mamounia

La Mamounia
Medina
United States
Gary
CA $1,170
CA $1,302 total
includes taxes & fees
Oct 11 - Oct 12
La Mamounia
A restaurant with a long table in the center, surrounded by chairs, and walls covered with plants.
A rooftop infinity pool with lounge chairs, a modern building, and a classical building in the background during sunset.
An outdoor bar area with wooden flooring, bar stools, and a seating arrangement.
A modern building entrance with a green wall and the word "EDITION" illuminated.

17. The Madrid EDITION

The Madrid EDITION
Madrid Centro
United States
Ifeolu
CA $645
CA $710 total
includes taxes & fees
Nov 9 - Nov 10
The Madrid EDITION
A lobby with ornate columns, a reception desk, and a staircase.
A grand lobby with high ceilings, ornate columns, and a grand piano. Tables and chairs are arranged for guests.
A balcony with two wicker lounge chairs, each with rolled towels, and potted plants.
A bar area with a striped counter, bar stools, and hanging spherical light fixtures.

18. Bernini Palace

Bernini Palace
Historic Centre of Florence
Canada
Jason
CA $431
CA $500 total
includes taxes & fees
Nov 9 - Nov 10
Bernini Palace
A table set for dining with a view of ancient ruins in the background.
A spacious lobby with a high ceiling, a central staircase, and a seating area with sofas and chairs.
A table set for dining with a view of a historic building on a hill.
A swimming pool with a person swimming, lounge chairs, and a wooden deck.

19. Electra Metropolis Athens

Electra Metropolis Athens
Athens City Centre
United States
Philippe
CA $416
CA $480 total
includes taxes & fees
Nov 2 - Nov 3
Electra Metropolis Athens
A spacious lobby with a central seating area, large windows, and a high ceiling.
A dining area with a wooden table, blue upholstered chairs, a decorative globe lamp, and a framed sign on the wall.
A hotel room with a bed, a TV, a desk, a chair, and a wardrobe.
Outdoor pool

20. Only YOU Hotel Sevilla

Only YOU Hotel Sevilla
San Pablo-Santa Justa
United Kingdom
jonathan
CA $261
CA $287 total
includes taxes & fees
Oct 18 - Oct 19
Only YOU Hotel Sevilla
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region.
Barcelona Airport Hotel

Barcelona Airport Hotel

Plaza de la Volateria, 3 El Prat de Llobregat
CA $244
CA $281 total
Nov 1 - Nov 2
includes taxes & fees
8.6/10 Excellent! (5,197 reviews)
Barcelona Airport Hotel
Hotel101- Madrid

Hotel101- Madrid

Av. de las Fuerzas Armadas, 328 Madrid
CA $109
CA $120 total
Oct 12 - Oct 13
includes taxes & fees
9.4/10 Exceptional! (1,631 reviews)
Hotel101- Madrid
Hotel 3K Barcelona

Hotel 3K Barcelona

Rua Laura Alves 10 Lisbon
CA $122
CA $142 total
Nov 3 - Nov 4
includes taxes & fees
Hotel 3K Barcelona
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Learn more about Mediterranean Region

During your stay in Mediterranean Region, you can discover things to see and do in the local area.

See all hotels in Mediterranean Region
Ancient Roman ruins with columns, a temple, and a cityscape at sunset.
Photo by Panya Sinsuebphol

Top Mediterranean Region Hotel Reviews

Transatlantik Hotel & Spa - Ultra All Inclusive

Transatlantik Hotel & Spa - Ultra All Inclusive

8/10 Good
"İss good"
HASAN YAHYA 4-night trip
Posted 5 months ago
Transatlantik Hotel & Spa - Ultra All Inclusive

Find out more about Mediterranean Region

Luxury is the name of the game at the best 5 Stars hotels in Mediterranean Region. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Mediterranean Region 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Mediterranean Region hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Mediterranean Region without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Mediterranean Region.