5 Stars Hotels in Mediterranean Region, from CA $155

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mediterranean Region 5 Star Hotels

Our top choices for Mediterranean Region 5-star hotels

Daily buffet breakfast (EUR 29 per person)

Grand Hyatt Athens

Grand Hyatt Athens
5.0 star property
Neos Kosmos
8.8 out of 10, Excellent, (1,056 reviews)
"Great location for a beautiful hotel. We really enjoyed our stay. Would stay again. The onsite hotel is a bit pricey though"
United States
Anissa
The price is CA $131
CA $155 total
includes taxes & fees
Mar 9 - Mar 10
Grand Hyatt Athens
Premium Room

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
5.0 star property
Downtown Barcelona
9.6 out of 10, Exceptional, (1,834 reviews)
" Clean room, great staff, best location in the heart of the Gothic Quarter"
United States
Gary
The price is CA $318
CA $377 total
includes taxes & fees
Feb 15 - Feb 16
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
Cocktail bar

Hyatt Regency Barcelona Tower

Hyatt Regency Barcelona Tower
5.0 star property
Bellvitge
9.0 out of 10, Wonderful, (1,023 reviews)
"Great hotel "
United States
Zoila Victoria
The price is CA $188
CA $218 total
includes taxes & fees
Feb 22 - Feb 23
Hyatt Regency Barcelona Tower
Bar (on property)

The Palace, a Luxury Collection Hotel, Madrid

The Palace, a Luxury Collection Hotel, Madrid
5.0 star property
Madrid Centro
9.2 out of 10, Wonderful, (1,005 reviews)
"Beautiful hotel great service and staff. Would highly recommend. "
Canada
Anna
The price is CA $517
CA $569 total
includes taxes & fees
Feb 22 - Feb 23
The Palace, a Luxury Collection Hotel, Madrid
Indoor pool, sun loungers

Barceló Torre de Madrid

Barceló Torre de Madrid
5.0 star property
Madrid Centro
9.4 out of 10, Exceptional, (2,341 reviews)
"A really great place to stay, extremely friendly and efficient staff, spotlessly clean and very well located, would highly recommend."
United Kingdom
Anthony
The price is CA $280
CA $308 total
includes taxes & fees
Feb 22 - Feb 23
Barceló Torre de Madrid
Exterior

Only YOU Hotel Sevilla

Only YOU Hotel Sevilla
5.0 star property
San Pablo-Santa Justa
9.8 out of 10, Exceptional, (642 reviews)
"Amazing staff and very well equipped hotel."
United Kingdom
Mohammed Abdul
The price is CA $258
CA $284 total
includes taxes & fees
Feb 22 - Feb 23
Only YOU Hotel Sevilla
2 bars/lounges

Sofitel Athens Airport

Sofitel Athens Airport
5.0 star property
Spata-Artemida
9.4 out of 10, Exceptional, (2,631 reviews)
"Great location, beautiful hotel, friendly staff"
United States
Cindy
The price is CA $381
CA $440 total
includes taxes & fees
Feb 27 - Feb 28
Sofitel Athens Airport
Suite (Nobu Suite) | View from room

Nobu Hotel Barcelona

Nobu Hotel Barcelona
5.0 star property
Sants-Montjuïc
9.0 out of 10, Wonderful, (1,226 reviews)
"Great spa and food"
United States
Pedro
The price is CA $326
CA $386 total
includes taxes & fees
Feb 16 - Feb 17
Nobu Hotel Barcelona
Premium bedding, down comforters, memory foam beds, in-room safe

Majestic Hotel & Spa Barcelona

Majestic Hotel & Spa Barcelona
5.0 star property
Eixample
9.2 out of 10, Wonderful, (1,002 reviews)
"Great Hotel"
United States
Andrea
The price is CA $501
CA $578 total
includes taxes & fees
Feb 23 - Feb 24
Majestic Hotel & Spa Barcelona
Porch

Eurostars Grand Marina

Eurostars Grand Marina
5.0 star property
Downtown Barcelona
8.8 out of 10, Excellent, (1,199 reviews)
"Staff were great, room was great, very convenient for the cruise port, shuttle bus stop only a couple of hundred yards away "
United States
Trevor
The price is CA $223
CA $272 total
includes taxes & fees
Feb 22 - Feb 23
Eurostars Grand Marina
Meeting facility

Athenaeum InterContinental by IHG

Athenaeum InterContinental by IHG
5.0 star property
Neos Kosmos
9.0 out of 10, Wonderful, (1,002 reviews)
"Amazing breakfast buffet."
United States
Robert Allen
The price is CA $217
CA $249 total
includes taxes & fees
Feb 27 - Feb 28
Athenaeum InterContinental by IHG
Front of property

UMusic Hotel Madrid

UMusic Hotel Madrid
5.0 star property
Madrid Centro
9.4 out of 10, Exceptional, (826 reviews)
"Great rooms, staff , location and very clean"
United Kingdom
James
The price is CA $341
CA $376 total
includes taxes & fees
Mar 11 - Mar 12
UMusic Hotel Madrid
2 outdoor pools

Hotel Arts Barcelona

Hotel Arts Barcelona
5.0 star property
Barceloneta
9.0 out of 10, Wonderful, (1,000 reviews)
"Amazing hotel "
United States
Sarah
The price is CA $576
CA $660 total
includes taxes & fees
Feb 20 - Feb 21
Hotel Arts Barcelona
2 restaurants, breakfast served

Grand Hyatt Barcelona

Grand Hyatt Barcelona
5.0 star property
Les Corts
9.2 out of 10, Wonderful, (1,492 reviews)
"Beautiful place, great service. "
United States
nicholas
The price is CA $247
CA $298 total
includes taxes & fees
Mar 8 - Mar 9
Grand Hyatt Barcelona
Exterior

InterContinental Lisbon by IHG

InterContinental Lisbon by IHG
5.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (1,001 reviews)
"It was a great stay."
United States
Elizabeth
The price is CA $239
CA $283 total
includes taxes & fees
Mar 1 - Mar 2
InterContinental Lisbon by IHG
Lobby sitting area

Avenida Palace

Avenida Palace
5.0 star property
Lisbon City Center
9.8 out of 10, Exceptional, (1,002 reviews)
"Every in the hotel was excellent -location, amenities, room service, breakfast."
United States
Leah
The price is CA $399
CA $436 total
includes taxes & fees
Feb 25 - Feb 26
Avenida Palace
Porch

Hotel Puerta América

Hotel Puerta América
5.0 star property
Chamartín
8.8 out of 10, Excellent, (1,000 reviews)
"Clean and unique design "
United States
Maide
The price is CA $237
CA $261 total
includes taxes & fees
Feb 15 - Feb 16
Hotel Puerta América
Lobby lounge

Only YOU Hotel Valencia

Only YOU Hotel Valencia
5.0 star property
Valencia City Centre
9.8 out of 10, Exceptional, (1,002 reviews)
"Excellent rooms, clean with great amenities. Location was great and walking distance to most locations. "
United Kingdom
Aryuat
The price is CA $251
CA $276 total
includes taxes & fees
Mar 1 - Mar 2
Only YOU Hotel Valencia
Exterior

Thompson Madrid, by Hyatt

Thompson Madrid, by Hyatt
5.0 star property
Madrid Centro
9.6 out of 10, Exceptional, (331 reviews)
"Excellent property at a great location! "
United States
Tanya
The price is CA $353
CA $388 total
includes taxes & fees
Feb 21 - Feb 22
Thompson Madrid, by Hyatt
2 restaurants, breakfast, lunch, dinner served; Mediterranean cuisine

Electra Palace Athens

Electra Palace Athens
5.0 star property
Athens City Centre
9.6 out of 10, Exceptional, (1,002 reviews)
"Excellent hotel, and staff."
United States
Dave
The price is CA $214
CA $251 total
includes taxes & fees
Feb 16 - Feb 17
Electra Palace Athens
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region.
Barcelona Airport Hotel

Barcelona Airport Hotel

Plaza de la Volateria, 3 El Prat de Llobregat
The price is CA $188 per night from Feb 24 to Feb 25
CA $188
CA $211 total
Feb 24 - Feb 25
includes taxes & fees
8.6/10 Excellent! (5,151 reviews)
Still don't see what you're looking for?
See all properties in Mediterranean Region.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mediterranean Region

During your stay in Mediterranean Region, you can discover things to see and do in the local area.

See all hotels in Mediterranean Region
Mazarrón, Spain

Top Mediterranean Region Hotel Reviews

Lamaro Hotel

Lamaro Hotel

10/10 Excellent
"We received a warm and helpful welcome at the reception desk. We were early, so they took our bags and gave us advice on what to do while we awaited check-in. The concierge helped us get tickets to a musical concert. Our room was very comfortable and tidy. The beds were exceptionally comfortable. The location is perfect for exploring the Gothic Quarter of Barcelona and the free breakfast helped us get fueled up for walking. "
Edgar 1-night trip
Posted 5 days ago
Lamaro Hotel
Grand Hyatt Barcelona

Grand Hyatt Barcelona

10/10 Excellent
"One of the best hotels I've ever stayed at"
Perry 3-night trip
Posted 3 weeks ago
Grand Hyatt Barcelona

Find out more about Mediterranean Region

Luxury is the name of the game at the best 5 Stars hotels in Mediterranean Region. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Mediterranean Region 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Mediterranean Region hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Mediterranean Region without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Mediterranean Region.