A coastal landscape with rocky cliffs, green hills, and a clear blue sea.

5 Stars Hotels in Mediterranean Region, from CA $104

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Check availability on Mediterranean Region 5 Star Hotels

Our top choices for Mediterranean Region 5-star hotels

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Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
5.0 star property
Downtown Barcelona
9.4 out of 10, Exceptional, (1,848 reviews)
"Great location, very clean and quiet"
United States
Diana
The price is CA $450
CA $538 total
includes taxes & fees
Jul 25 - Jul 26
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
Daily buffet breakfast for a fee

Grand Hyatt Athens

Grand Hyatt Athens
5.0 star property
Neos Kosmos
8.6 out of 10, Excellent, (1,306 reviews)
"Stay there when in Athens"
United States
Lazaros
The price is CA $263
CA $324 total
includes taxes & fees
Jul 15 - Jul 16
Grand Hyatt Athens
3 restaurants; breakfast, lunch, and dinner served

Corinthia Lisbon

Corinthia Lisbon
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,278 reviews)
"Booked into the hotel last minute because our flight was cancelled. Great stay and the spa was a wonderful treat."
United Kingdom
Trisha
The price is CA $332
CA $365 total
includes taxes & fees
Aug 1 - Aug 2
Corinthia Lisbon
Exterior

Concorde De Luxe Resort Lara Antalya - Prive Ultra All Inclusive

Concorde De Luxe Resort Lara Antalya - Prive Ultra All Inclusive
5.0 star property
Lara
9.6 out of 10, Exceptional, (1,124 reviews)
"Great Place"
United States
Kirk
The price is CA $717
CA $795 total
includes taxes & fees
Aug 8 - Aug 9
Concorde De Luxe Resort Lara Antalya - Prive Ultra All Inclusive
2 restaurants; breakfast, lunch, dinner, and brunch served

Grand Hyatt Barcelona

Grand Hyatt Barcelona
5.0 star property
Les Corts
9.2 out of 10, Wonderful, (1,577 reviews)
"Great place to stay. "
United States
Le
The price is CA $352
CA $430 total
includes taxes & fees
Jul 18 - Jul 19
Grand Hyatt Barcelona
Water park

Swandor Hotels & Resort Topkapi Palace - All Inclusive

Swandor Hotels & Resort Topkapi Palace - All Inclusive
5.0 star property
Lara
9.0 out of 10, Wonderful, (2,141 reviews)
"We loved our stay. Very nice place to relax."
United States
Blerina
The price is CA $307
CA $340 total
includes taxes & fees
Aug 2 - Aug 3
Swandor Hotels & Resort Topkapi Palace - All Inclusive
Front of property

EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,414 reviews)
"Had a great stay"
United States
Benjamin
The price is CA $362
CA $397 total
includes taxes & fees
Aug 9 - Aug 10
EPIC SANA Marques Hotel
Pool views, serves lunch and dinner

W Barcelona

W Barcelona
5.0 star property
Barceloneta
8.8 out of 10, Excellent, (1,006 reviews)
"Excellent stay"
United States
Sos
The price is CA $689
CA $800 total
includes taxes & fees
Jul 13 - Jul 14
W Barcelona
2 restaurants; breakfast, lunch, dinner, and brunch served

Divani Palace Acropolis

Divani Palace Acropolis
5.0 star property
Athens City Centre
9.0 out of 10, Wonderful, (1,012 reviews)
"Great location"
United States
Periklis
The price is CA $269
CA $331 total
includes taxes & fees
Aug 7 - Aug 8
Divani Palace Acropolis
Cocktail bar

Hyatt Regency Barcelona Tower

Hyatt Regency Barcelona Tower
5.0 star property
Bellvitge
9.0 out of 10, Wonderful, (1,163 reviews)
"Such a great stay!"
United States
Latasha
The price is CA $225
CA $264 total
includes taxes & fees
Aug 9 - Aug 10
Hyatt Regency Barcelona Tower
Lobby sitting area

Athenaeum InterContinental by IHG

Athenaeum InterContinental by IHG
5.0 star property
Neos Kosmos
9.0 out of 10, Wonderful, (1,004 reviews)
"This is an amazing place. Beautiful, clean hotel with extremely nice staff. Highly recommended for anyone traveling and staying in Athens."
United States
John
The price is CA $284
CA $347 total
includes taxes & fees
Jul 23 - Jul 24
Athenaeum InterContinental by IHG
Suite (Nobu Suite) | View from room

Nobu Hotel Barcelona

Nobu Hotel Barcelona
5.0 star property
Sants-Montjuïc
9.0 out of 10, Wonderful, (1,332 reviews)
"Very conveniently located right next to a major train station for public transportation. The staff was extremely helpful when our AC unit was not working one day and helping us make a reservation at a Costa Brava beach club. Clean, well appointed and very comfortable bed."
United States
Kristina
The price is CA $418
CA $503 total
includes taxes & fees
Jul 19 - Jul 20
Nobu Hotel Barcelona
Lobby

EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,059 reviews)
"Really nice location and resort. Love this property and staff were very helpful and friendly."
United States
Diana
The price is CA $270
CA $299 total
includes taxes & fees
Jul 23 - Jul 24
EPIC SANA Lisboa Hotel
Rooftop terrace

Palacio de los Duques Gran Meliá - The Leading Hotels of the World

Palacio de los Duques Gran Meliá - The Leading Hotels of the World
5.0 star property
Madrid Centro
9.8 out of 10, Exceptional, (916 reviews)
"Wonderful stay"
United Kingdom
Huiqi
The price is CA $570
CA $627 total
includes taxes & fees
Aug 5 - Aug 6
Palacio de los Duques Gran Meliá - The Leading Hotels of the World
Porch

Eurostars Grand Marina

Eurostars Grand Marina
5.0 star property
Downtown Barcelona
9.0 out of 10, Wonderful, (1,336 reviews)
"Great breakfast and very friendly staff"
United States
Jeremy
The price is CA $238
CA $304 total
includes taxes & fees
Jul 19 - Jul 20
Eurostars Grand Marina
2 restaurants; breakfast, lunch, and dinner served

Electra Metropolis Athens

Electra Metropolis Athens
5.0 star property
Athens City Centre
9.6 out of 10, Exceptional, (1,199 reviews)
"Great hotel in a good location."
United States
Patricia
The price is CA $509
CA $604 total
includes taxes & fees
Aug 3 - Aug 4
Electra Metropolis Athens
Indoor pool, sun loungers

Barceló Torre de Madrid

Barceló Torre de Madrid
5.0 star property
Madrid Centro
9.4 out of 10, Exceptional, (2,630 reviews)
"Great breakfast and very clean"
Canada
Nasser
The price is CA $272
CA $299 total
includes taxes & fees
Jul 13 - Jul 14
Barceló Torre de Madrid
Exterior

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
5.0 star property
Historical Center
9.4 out of 10, Exceptional, (1,001 reviews)
"Lovely room. Breakfast was amazing and the bar was great service. Food was the best at this hotel"
United Kingdom
Mandip
The price is CA $577
CA $635 total
includes taxes & fees
Aug 9 - Aug 10
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Library

Royal Olympic Hotel

Royal Olympic Hotel
5.0 star property
Athens City Centre
8.0 out of 10, Very good, (1,002 reviews)
"Nice stay, location is good and close to main sights."
United Kingdom
Andrea
The price is CA $212
CA $265 total
includes taxes & fees
Jul 12 - Jul 13
Royal Olympic Hotel
Seasonal outdoor pool, pool umbrellas, sun loungers

Zeus Wyndham Grand Athens

Zeus Wyndham Grand Athens
5.0 star property
Athens City Centre
8.0 out of 10, Very good, (1,154 reviews)
"The pool was a great addition to the vacation. Helpful staff good food and well kept premises."
United States
Charles
The price is CA $304
CA $371 total
includes taxes & fees
Jul 24 - Jul 25
Zeus Wyndham Grand Athens
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region.
Hotel101- Madrid

Hotel101- Madrid

Av. de las Fuerzas Armadas, 328 Madrid
The price is CA $95 per night from Jul 12 to Jul 13
CA $95
CA $104 total
Jul 12 - Jul 13
includes taxes & fees
9.6/10 Exceptional! (808 reviews)
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Learn more about Mediterranean Region

During your stay in Mediterranean Region, you can discover things to see and do in the local area.

See all hotels in Mediterranean Region
A winding road through a mountainous landscape with the sun setting behind the hills.

Top Mediterranean Region Hotel Reviews

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

10/10 Excellent
"Great place and good location. Exceeded expectations."
brice 1-night trip
Posted less than an hour ago
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Find out more about Mediterranean Region

Luxury is the name of the game at the best 5 Stars hotels in Mediterranean Region. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Mediterranean Region 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Mediterranean Region hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Mediterranean Region without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Mediterranean Region.