Title: 5 Stars Hotels in Mediterranean Region, from CA $240 - Find Cheap Mediterranean Region Hotels With 5 Stars | Expedia.ca [Mediterranean Region Travel Guide](https://expedia.ca/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Vacation Rentals in Mediterranean Region](https://expedia.ca/Mediterranean-Region-Vacation-Rentals.d844522342175883264.Travel-Guide-VacationRentals)[Flights to Mediterranean Region](https://expedia.ca/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Rentals](https://expedia.ca/Car-Rentals-In-Mediterranean-Region.d844522342175883264.Car-Rental-Guide)[Mediterranean Region Vacation Packages](https://expedia.ca/Mediterranean-Region.d844522342175883264.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/abc24df6f2e3266327aa8b559e87e79a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Mediterranean Region, from CA $240 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mediterranean Region 5 Star Hotels Tonight [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-09-29&endDate=2025-09-30&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-09-30&endDate=2025-10-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-10-03&endDate=2025-10-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=844522342175883264&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mediterranean Region 5 Star Hotels ![Mediterranean cuisine](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed (Penthouse)](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/45d10bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/595f7b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed (Two Level) | View from room](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/23d63f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt Athens Neos Kosmos 8.8/10 Excellent (858) "Great rooms, great restaurants, great location. " CA $189 CA $240 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) ![Couples treatment rooms, body treatments, body scrubs, facials, massages](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/78fd0d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/cfd61a7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/b8626219.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive lounge](https://images.trvl-media.com/lodging/1000000/690000/688200/688125/46960959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel Athens Airport Spata-Artemida 9.4/10 Exceptional (2708) "Great hotel!" CA $418 CA $499 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Athens-Hotels-Sofitel-Athens-Airport.h688125.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/a07cf64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/9f1f2700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/2812618d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Spanish cuisine](https://images.trvl-media.com/lodging/1000000/10000/3400/3388/9b2b1f33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lamaro Hotel Downtown Barcelona 9.6/10 Exceptional (1809) "A lovely hotel, excellent location within walking distance of many sights. " CA $429 CA $499 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/792b4779.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/3c511264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Iconic)](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/7c219627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/17400/17348/w3840h2440x0y3-e37b92aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt Barcelona Les Corts 9.2/10 Wonderful (1403) "We enjoyed our stay it was great! " CA $342 CA $404 total includes taxes & fees Oct 17 - Oct 18 [](https://www.expedia.ca/Barcelona-Hotels-Hotel-SOFIA-Barcelona.h17348.Hotel-Information) ![3 restaurants, breakfast, lunch, dinner served; Portuguese cuisine](https://images.trvl-media.com/lodging/1000000/10000/4100/4014/b31c4e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/1000000/10000/4100/4014/3434b802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; Portuguese cuisine](https://images.trvl-media.com/lodging/1000000/10000/4100/4014/b4541a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4100/4014/7f05d506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Corinthia Lisbon Lisbon City Center 9.6/10 Exceptional (1206) "Great location and hotel" CA $472 CA $514 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Lisbon-District-Hotels-Corinthia-Lisbon.h4014.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/30000/28300/28279/3e96c0d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Single Bed](https://images.trvl-media.com/lodging/1000000/30000/28300/28279/8400e099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, Select Comfort beds](https://images.trvl-media.com/lodging/1000000/30000/28300/28279/10393ed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/28300/28279/71c248ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Barcelona by IHG El Poble-sec 9.2/10 Wonderful (1017) "Excellent stay and staff very helpful, would stay again. Location good and with walking distance to main attractions. " CA $342 CA $404 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Barcelona-Hotels-InterContinental-Barcelona.h28279.Hotel-Information) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/639d39e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/cae5c38c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/4e42dcf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/19600/19591/cc04ed54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Athenaeum InterContinental by IHG Neos Kosmos 9.0/10 Wonderful (1012) "Great staff and food. " CA $207 CA $260 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Athens-Hotels-Athenaeum-InterContinental.h19591.Hotel-Information) ![Japanese cuisine](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/de597f46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 5:00 PM, free cabanas](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/a6998e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Nobu Suite)](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/aad463a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Sake) | City view](https://images.trvl-media.com/lodging/40000000/39070000/39067400/39067368/fc4fdb1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu Hotel Barcelona Sants-Montjuïc 9.0/10 Wonderful (1110) "Amazing place!" CA $390 CA $456 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/Barcelona-Hotels-Nobu-Hotel-Barcelona.h39067368.Hotel-Information) ![1 bedroom, premium bedding, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/17643795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/3792e200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/807e046f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, Select Comfort beds, minibar](https://images.trvl-media.com/lodging/16000000/15380000/15372000/15371941/8f047351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barceló Torre de Madrid Madrid Centro 9.4/10 Exceptional (2167) "Great location and hotel is really nice" CA $319 CA $351 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Madrid-Hotels-Barcelo-Torre-De-Madrid.h15371941.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/21700/21663/1add5596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21700/21663/7cdef21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, beach umbrellas, beach towels, scuba diving](https://images.trvl-media.com/lodging/1000000/30000/21700/21663/16845a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panorama Suite (Urban Chic Lounge Access)](https://images.trvl-media.com/lodging/1000000/30000/21700/21663/62da7c63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Akra Antalya Lara 9.4/10 Exceptional (1448) "Excellent place to stay" CA $361 CA $404 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Antalya-Hotels-Akra-Hotel.h21663.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2580000/2578700/2578680/2afbacdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool views, serves lunch and dinner](https://images.trvl-media.com/lodging/3000000/2580000/2578700/2578680/93547d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/3000000/2580000/2578700/2578680/9e1f9ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2580000/2578700/2578680/6d0a3953.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Barcelona Barceloneta 8.8/10 Excellent (1018) "Great location" CA $587 CA $673 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Barcelona-Hotels-W-Barcelona.h2578680.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/6700/6670/5ad0db00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6700/6670/1a800c16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/1000000/10000/6700/6670/ed25a6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 25 per person)](https://images.trvl-media.com/lodging/1000000/10000/6700/6670/46164f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Olympic Hotel Athens City Centre 8.0/10 Very good (1021) "Close to Acropolis and shopping. " CA $225 CA $280 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Athens-Hotels-Royal-Olympic-Hotel.h6670.Hotel-Information) ![Outdoor pool, open 8:30 AM to 2:30 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/570000/562600/562576/41ce162a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/562600/562576/99e7d4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Suite](https://images.trvl-media.com/lodging/1000000/570000/562600/562576/2eb42df2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/570000/562600/562576/6d315874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Divani Palace Acropolis Athens City Centre 8.8/10 Excellent (1024) "Very nice stay, would come back " CA $370 CA $445 total includes taxes & fees Oct 11 - Oct 12 [](https://www.expedia.ca/Athens-Hotels-Divani-Palace-Acropolis.h562576.Hotel-Information) ![Cocktail bar](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/3f36a705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/195f35b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/752b0263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/26a7a198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Barcelona Tower Bellvitge 9.0/10 Wonderful (1052) "Beautiful accommodations and awesome seafood restaurant next door." CA $285 CA $324 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Barcelona-Hotels-Hyatt-Regency-Barcelona-Tower.h1337977.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/14000/13999/84743cc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14000/13999/3d12f7de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/14000/13999/3eacd343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14000/13999/6e5f7642.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bernini Palace Historic Centre of Florence 9.6/10 Exceptional (1021) "Great place to stay" CA $560 CA $642 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Florence-Hotels-Bernini-Palace.h13999.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/1d089f4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Mediterranean cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/f0bcfd4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/6c3d2718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/5100/5002/d80c7ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Majestic Hotel & Spa Barcelona Eixample 9.2/10 Wonderful (1011) "Beautiful hotel and great service! " CA $587 CA $673 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Barcelona-Hotels-Majestic-Hotel-Spa-Barcelona.h5002.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/0cd6fac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/c8a265eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/b487ca11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/880000/871900/871862/88083424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eurostars Grand Marina Downtown Barcelona 8.8/10 Excellent (1126) "The view and the location of the hotel was the best. " CA $307 CA $365 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Barcelona-Hotels-Eurostars-Grand-Marina.h871862.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/2000000/1110000/1109000/1108961/w5472h3643x3y0-51a8c7bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1110000/1109000/1108961/e4433be7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1110000/1109000/1108961/w5468h3649x5y0-f16d17a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/2000000/1110000/1109000/1108961/ef27ca7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EPIC SANA Marques Hotel Lisbon City Center 9.6/10 Exceptional (1183) "Excellent location, very good facilities " CA $380 CA $416 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Lisbon-District-Hotels-EPIC-SANA-Marques-Hotel.h1108961.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/440000/438500/438418/cd4b1795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/440000/438500/438418/47e87212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/440000/438500/438418/b24431ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 restaurants, breakfast, lunch, dinner served; Moroccan cuisine](https://images.trvl-media.com/lodging/1000000/440000/438500/438418/250bb5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Mamounia Medina 9.2/10 Wonderful (626) "Excellent stay for a week. So many options and the rooms are beautiful. " CA $1,240 CA $1,379 total includes taxes & fees Oct 4 - Oct 5 [](https://www.expedia.ca/Marrakech-Hotels-La-Mamounia.h438418.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/372ab6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/e2ae3d67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7064e389.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/63569bc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Raphaël – Relais & Châteaux Rome City Centre 9.2/10 Wonderful (1008) "Staff was amazing, Harp player at breakfast was wonderful. And the food choices was so good!" CA $721 CA $826 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mediterranean-Region-Hotels.s50-0-d844522342175883264.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mediterranean-Region-Hotels.s50-0-d844522342175883264.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region. ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Barcelona Airport Hotel Plaza de la Volateria, 3, Poligono Mas Blau, El Prat de Llobregat CA $217 CA $243 total Oct 20 - Oct 21 includes taxes & fees 8.6/10 Excellent! (5,117 reviews) [](https://expedia.ca/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Napoleon Hotel](https://images.trvl-media.com/lodging/1000000/10000/6600/6548/9e2b5c71_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Napoleon Hotel Piazza Vittorio Emanuele II 105, Rome, RM CA $287 CA $340 total Oct 30 - Oct 31 includes taxes & fees 8.4/10 Very Good! (1,022 reviews) [](https://expedia.ca/Rome-Hotels-Napoleon-Hotel.h6548.Hotel-Information) ![Radisson Blu Hotel](https://images.trvl-media.com/lodging/1000000/530000/524600/524550/907de448_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Radisson Blu Hotel Avenida Marechal Craveiro Lopes, 390, Campo Grande, Lisbon CA $218 CA $245 total Oct 26 - Oct 27 includes taxes & fees 8.2/10 Very Good! (2,083 reviews) [](https://expedia.ca/Lisbon-District-Hotels-Radisson-Blu-Hotel.h524550.Hotel-Information) Still don't see what you're looking for? [See all properties in Mediterranean Region.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=844522342175883264&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=844522342175883264&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=844522342175883264&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=844522342175883264&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=844522342175883264&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=30%2F09%2F2025&endDate=01%2F10%2F2025®ionId=844522342175883264&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mediterranean Region During your stay in Mediterranean Region, you can discover things to see and do in the local area. [See all hotels in Mediterranean Region](https://www.expedia.ca/Hotel-Search?startDate=2025-10-13&endDate=2025-10-14&adults=2®ionId=844522342175883264) ![Roman Forum featuring building ruins and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/20000/20269-Roman-Forum.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Mediterranean Region Hotel Reviews ![Grand Hyatt Barcelona](//images.trvl-media.com/lodging/1000000/20000/17400/17348/792b4779_y.jpg) ### Grand Hyatt Barcelona 10/10 Excellent "STAFF WAS GREAT. NO ISSUES. VERY HELPFUL" [](https://expedia.ca/Barcelona-Hotels-Hotel-SOFIA-Barcelona.h17348.Hotel-Information) ![Akra Antalya](//images.trvl-media.com/lodging/1000000/30000/21700/21663/1add5596_y.jpg) ### Akra Antalya 10/10 Excellent "Clean " [](https://expedia.ca/Antalya-Hotels-Akra-Hotel.h21663.Hotel-Information) ![Grand Hyatt Athens](//images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f_y.jpg) ### Grand Hyatt Athens 10/10 Excellent "Amazing pool with a view of the acropolis, great option of a free shuttle into the centre although a 40 minute walk otherwise. Very safe area" [](https://expedia.ca/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) ![Swandor Hotels & Resort Topkapi Palace - All Inclusive](//images.trvl-media.com/lodging/2000000/1280000/1271900/1271843/6ea3cfe9_y.jpg) ### Swandor Hotels & Resort Topkapi Palace - All Inclusive 10/10 Excellent "Staff were courteous, lots todo and see arouns, great for families and large groups alike. A vast array of food options. Highly recommend " [](https://expedia.ca/Antalya-Hotels-Swandor-Hotels-Resort-Topkapi-Palace-All-Inclusive.h1271843.Hotel-Information) ![Crystal Sunset Luxury Resort & Spa - All Inclusive](//images.trvl-media.com/lodging/9000000/8130000/8125500/8125448/70be5020_y.jpg) ### Crystal Sunset Luxury Resort & Spa - All Inclusive 10/10 Excellent "Great property and fantastic team! " [](https://expedia.ca/Side-Hotels-Crystal-Sunset-Luxury-Resort-Spa-All-Inclusive.h8125448.Hotel-Information) ## Find out more about Mediterranean Region Luxury is the name of the game at the best 5 Stars hotels in Mediterranean Region. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Mediterranean Region 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them. Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Mediterranean Region hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Mediterranean Region without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Mediterranean Region.