5 Stars Hotels in La Mesa, California from CA $354

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Check prices for these dates

Tonight
Nov 8 - Nov 9
Tomorrow
Nov 9 - Nov 10
Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

Our top choices for La Mesa 5-star hotels

A multi-story hotel with a prominent 'PENDR' sign, large windows, and a corner entrance.

1. Pendry San Diego

Pendry San Diego
5.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,004 reviews)
"Very nice property in the downtown."
United States
Vasilios
The price is CA $417
CA $561 total
includes taxes & fees
Nov 29 - Nov 30
Pendry San Diego
A large, historic hotel with multiple floors, a central courtyard, and a prominent entrance.

2. The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego
5.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,000 reviews)
"Location, staff"
United States
Bijan
The price is CA $371
CA $431 total
includes taxes & fees
Nov 23 - Nov 24
The US Grant, a Luxury Collection Hotel, San Diego
A hotel with outdoor seating areas, a pool, and a view of the ocean.

3. L'Auberge Del Mar

L'Auberge Del Mar
5.0 star property
Del Mar
8.8 out of 10, Excellent, (888 reviews)
"The best part of this property was the ocean view from the lobby entrance and dining area. That’s what you’re paying for. Other than that, the king room was mediocre with a small bathroom and little counter space."
United States
Jan
The price is CA $564
CA $743 total
includes taxes & fees
Nov 15 - Nov 16
L'Auberge Del Mar
A resort with a large swimming pool, multiple buildings, and surrounding greenery.

4. Fairmont Grand Del Mar

Fairmont Grand Del Mar
5.0 star property
Carmel Valley
9.4 out of 10, Exceptional, (1,001 reviews)
"Excellent property and stay"
United States
James
The price is CA $660
CA $873 total
includes taxes & fees
Nov 15 - Nov 16
Fairmont Grand Del Mar
A poolside bar with outdoor seating, a pool, and a view of a golf course at sunset.

5. The Lodge at Torrey Pines

The Lodge at Torrey Pines
5.0 star property
Torrey Pines
9.4 out of 10, Exceptional, (1,003 reviews)
"The property was beautiful and the staff was very friendly and accommodating with our dog. We will definitely be back!"
United States
Alan
The price is CA $630
CA $823 total
includes taxes & fees
Dec 9 - Dec 10
The Lodge at Torrey Pines
A curved sofa with multiple cushions, a glass table with a tray of croissants and two cups, and a fire feature.

6. The Bower Coronado

The Bower Coronado
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (352 reviews)
"I had a fantastic experience at The Bower! Room was very clean, bed was very comfortable, location was excellent. Front desk was welcoming and very friendly."
United States
Irina
The price is CA $355
CA $469 total
includes taxes & fees
Nov 15 - Nov 16
The Bower Coronado
View from room

7. Shore House at The Del, LXR Hotels & Resorts

Shore House at The Del, LXR Hotels & Resorts
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (191 reviews)
"It was a beautiful resort"
United States
Tisha
The price is CA $902
CA $1,081 total
includes taxes & fees
Nov 20 - Nov 21
Shore House at The Del, LXR Hotels & Resorts
A spacious living room with a large gray sofa, a coffee table, and a view of the ocean through large windows.

8. Beach Village at The Del, LXR Hotels & Resorts

Beach Village at The Del, LXR Hotels & Resorts
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (149 reviews)
"Wonderful stay!"
United States
Maria
The price is CA $1,043
CA $1,226 total
includes taxes & fees
Nov 15 - Nov 16
Beach Village at The Del, LXR Hotels & Resorts
A modern resort with a swimming pool, a covered outdoor area, and a sunset view.

9. Rancho Valencia Resort and Spa

Rancho Valencia Resort and Spa
5.0 star property
Rancho Santa Fe
9.8 out of 10, Exceptional, (150 reviews)
"This resort is dreamy! The staff is incredible and sweet!"
United States
Lilit
The price is CA $1,553
CA $1,794 total
includes taxes & fees
Nov 9 - Nov 10
Rancho Valencia Resort and Spa

Top La Mesa Hotel Reviews

A multi-story hotel with a prominent 'PENDR' sign, large windows, and a corner entrance.
Pendry San Diego

Pendry San Diego

Pendry San Diego
Downtown San Diego

10/10 Excellent

Amazing hotel, amenities and staff. Also, great value.
Canada
James
Reviewed September 5, 2026
Pendry San Diego

Find out more about La Mesa

Five Star Hotels in La Mesa

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made La Mesa so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in La Mesa and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in La Mesa

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to La Mesa

The results are in, and La Mesa 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in La Mesa! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in La Mesa today and settle down in the lap of luxury tomorrow.

Frequently Asked Questions

What are the best 5-star hotels in La Mesa?

If you're seeking a 5-star experience, THE US GRANT, a Luxury Collection Hotel, San Diego offers one of the best of them according to Expedia customer reviews. Book a room at this La Mesa escape and you'll get the highest standard of service, upscale furnishings and top-notch facilities.

How much does it cost to stay in a 5-star hotel in La Mesa?

You'll find a range of pricing options for a 5-star hotel in La Mesa on Expedia. How much you'll pay will depend on your vacation dates, trip length and other factors. Compare available properties for your preferred dates and use our pricing and other filters to find the perfect high-end stay.

  • Search for the lowest price per night from CA $354

What makes a hotel 5 stars in La Mesa?

Exceptional guest service is the foundation of every 5-star hotel in La Mesa. From the moment you enter the lobby, staff cater to your every need, whether recommending activities or providing a nightly turn-down service. Plus, hotels must feature upscale amenities to be entitled to a 5-star rating. These can include luxury baths, a wellness centre, swimming pools, fine dining kitchens and knowledgeable concierge.

Are there any 5-star all-inclusive resorts in La Mesa?

Use our filters to find a high-end retreat in La Mesa where most of what you need is included in the price. Next, refine your results for accommodations that have a rating of 5 stars and are described as "All inclusive." The most important thing on the schedule at these stays? Relaxation and indulgence.

What are the top 5-star spa hotels in La Mesa?

Pendry San Diego combines upscale accommodations with pampering well-being treatments and experiences. Choose from a menu of facials, massages and more at this well-known 5-star spa stay in La Mesa.

Are there any 5-star vacation rentals in La Mesa?

There are no 5-star vacation rentals in La Mesa on our site, but there are a range of other highly rated properties worth looking into. Search through our vacation rentals in La Mesa to discover the best place for your getaway.

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