Title: 4 Stars Hotels in Mesopotamia, Ohio - Find Cheap Mesopotamia Hotels With 4 Stars | Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx3000453277)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d3000453277.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d3000453277.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d3000453277.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d3000453277.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d3000453277.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Mesopotamia, Ohio ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesopotamia 4 Star Hotels Tonight [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2025-10-10&endDate=2025-10-11&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2025-10-11&endDate=2025-10-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mesopotamia 4 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mesopotamia-Hotels.s40-0-d3000453277.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mesopotamia-Hotels.s40-0-d3000453277.Travel-Guide-Filter-Hotels) ## Top Mesopotamia Hotel Reviews ## Find out more about Mesopotamia If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Mesopotamia are calling your name. Known for providing first-rate service in amazing locations, each of the Mesopotamia 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Mesopotamia. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Mesopotamia, Ohio, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Mesopotamia hotels with 4 Stars provide everything you need to unwind in style. ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Mesopotamia? > We can help you easily find the perfect 4-star hotel for your getaway in Mesopotamia. Use our handy filter tool to tailor your search by things like price, amenities and property star rating and get access to unbeatable deals in a few clicks. > > > > - Search for the lowest price ### What's the difference between 5-star and 4-star hotels in Mesopotamia? > If you choose to spend your vacation at a 4-star hotel in Mesopotamia, you'll usually find plenty of conveniences to ensure you're comfortable, such as a restaurant, gym and pool. You can experience excellent service and upmarket surroundings. Pick a 5-star hotel and you'll have access to a few more perks — think on-site spas, concierge assistance and indulgent turndown services. You'll most likely get extra amenities and exclusive services at a 5-star getaway, though both are superb options for luxury guests. ### Does Mesopotamia have any 4-star all-inclusive resorts? > Enjoy a stress-free vacation experience where everything is included in one upfront price by using our "All inclusive" filter. Budgeting is a piece of cake when your room, food, activities and entertainment are already taken care of. Eager for more options? 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