A coastal landscape with rocky cliffs, green hills, and a clear blue sea.

4 Stars Hotels in Mediterranean Region, from CA $107

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Check availability on Mediterranean Region 4 Star Hotels

Our top choices for Mediterranean Region 4-star hotels

Interior

Hotel101- Madrid

Hotel101- Madrid
4.0 star property
Barajas
9.6 out of 10, Exceptional, (850 reviews)
"Nice place to stay"
United States
CESAR A
The price is CA $98
CA $107 total
includes taxes & fees
Jul 21 - Jul 22
Hotel101- Madrid
Lobby sitting area

Barcelona Airport Hotel

Barcelona Airport Hotel
4.0 star property
El Prat de Llobregat
8.6 out of 10, Excellent, (5,156 reviews)
"I liked that was close to the airport and had a shuttle bus."
Canada
Catherine
The price is CA $195
CA $221 total
includes taxes & fees
Aug 5 - Aug 6
Barcelona Airport Hotel
Terrace/patio

Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo
4.0 star property
Rome City Centre
8.6 out of 10, Excellent, (1,018 reviews)
"Great location and wonderful experience"
United States
Tripti
The price is CA $294
CA $348 total
includes taxes & fees
Aug 10 - Aug 11
Bettoja Hotel Mediterraneo
Outdoor pool, a heated pool, open 9:00 AM to 8:00 PM, pool umbrellas

The Stanley

The Stanley
4.0 star property
Athens City Centre
8.8 out of 10, Excellent, (2,323 reviews)
"Great location, super great food."
United States
marco
The price is CA $282
CA $337 total
includes taxes & fees
Aug 9 - Aug 10
The Stanley
Design Double or Twin Room | View from room

Hotel Royal Ramblas

Hotel Royal Ramblas
4.0 star property
Downtown Barcelona
9.0 out of 10, Wonderful, (1,025 reviews)
"Excellent breakfast with very good location"
United States
Hector
The price is CA $274
CA $331 total
includes taxes & fees
Jul 27 - Jul 28
Hotel Royal Ramblas
Exterior

Hotel Quirinale

Hotel Quirinale
4.0 star property
Rome City Centre
8.8 out of 10, Excellent, (1,940 reviews)
"Great location. Nice breakfast! Staff were friendly and helpful!"
United States
Tawnya
The price is CA $239
CA $287 total
includes taxes & fees
Jul 28 - Jul 29
Hotel Quirinale
Meeting facility

Hotel Chamartin The One

Hotel Chamartin The One
4.0 star property
Chamartín
8.6 out of 10, Excellent, (1,094 reviews)
"The rooms were clean and location is good."
United States
Bassam
The price is CA $128
CA $141 total
includes taxes & fees
Aug 9 - Aug 10
Hotel Chamartin The One
Exterior

Hotel Emperador

Hotel Emperador
4.0 star property
Madrid Centro
9.2 out of 10, Wonderful, (2,191 reviews)
"Great location. Clean and enjoyable stay."
United States
Genevieve
The price is CA $247
CA $272 total
includes taxes & fees
Jul 19 - Jul 20
Hotel Emperador
2 bars/lounges, poolside bar

The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini
4.0 star property
San Lorenzo
9.0 out of 10, Wonderful, (1,456 reviews)
"Great place to stay "
United States
antonella
The price is CA $140
CA $177 total
includes taxes & fees
Aug 9 - Aug 10
The Social Hub Florence Lavagnini
Suite Exterior (Aduana)

Hotel Regina

Hotel Regina
4.0 star property
Madrid Centro
9.8 out of 10, Exceptional, (2,321 reviews)
"Great location! Rooms were updated and very nice"
United States
Jasmin Mary
The price is CA $276
CA $303 total
includes taxes & fees
Jul 19 - Jul 20
Hotel Regina
2 restaurants; breakfast, lunch, dinner, and brunch served

Titania Hotel

Titania Hotel
4.0 star property
Athens City Centre
8.0 out of 10, Very good, (989 reviews)
"Staff were amazing at the restaurant upstairs. Room was nice and clean."
United Kingdom
Tony
The price is CA $197
CA $240 total
includes taxes & fees
Jul 23 - Jul 24
Titania Hotel
Breakfast, lunch and dinner served

Hilton Rome Airport

Hilton Rome Airport
4.0 star property
Fiumicino
8.2 out of 10, Very good, (3,256 reviews)
"Location to the airport was great"
United States
Gerek
The price is CA $336
CA $385 total
includes taxes & fees
Jul 21 - Jul 22
Hilton Rome Airport
Front of property

Napoleon Hotel

Napoleon Hotel
4.0 star property
Rome City Centre
8.6 out of 10, Excellent, (1,017 reviews)
"Clean room, delicious breakfast and a charming character. The location is decently close to Colleseum and train station."
United States
BURCIN
The price is CA $165
CA $205 total
includes taxes & fees
Jul 19 - Jul 20
Napoleon Hotel
Exterior

Radisson Blu Hotel

Radisson Blu Hotel
4.0 star property
Lisbon City Center
8.2 out of 10, Very good, (2,386 reviews)
"Great hotel, centrally located."
Canada
Donna
The price is CA $182
CA $206 total
includes taxes & fees
Jul 15 - Jul 16
Radisson Blu Hotel
2 restaurants; lunch and dinner served

Moxy Barcelona

Moxy Barcelona
4.0 star property
Sants-Montjuïc
8.6 out of 10, Excellent, (644 reviews)
"Amazing stay ! Beautiful hotel"
United States
Roberto Christian
The price is CA $211
CA $262 total
includes taxes & fees
Jul 26 - Jul 27
Moxy Barcelona
Daily buffet breakfast for a fee

Holiday Inn Lisbon by IHG

Holiday Inn Lisbon by IHG
4.0 star property
Lisbon City Center
8.6 out of 10, Excellent, (1,023 reviews)
"Great breakfast and nice room"
United States
Melanio
The price is CA $146
CA $192 total
includes taxes & fees
Jul 21 - Jul 22
Holiday Inn Lisbon by IHG
Seasonal outdoor pool

Novotel Madrid Center

Novotel Madrid Center
4.0 star property
Salamanca
9.2 out of 10, Wonderful, (1,266 reviews)
"Great location Good family rooms Good restaurant and bar"
United States
Alfredo
The price is CA $246
CA $271 total
includes taxes & fees
Jul 28 - Jul 29
Novotel Madrid Center
Breakfast, lunch and dinner served

Hilton Garden Inn Rome Airport

Hilton Garden Inn Rome Airport
4.0 star property
Fiumicino
8.2 out of 10, Very good, (3,944 reviews)
"Great place to stay for a long layover. Staff were great, very clean, and great breakfast as well"
United States
Run
The price is CA $265
CA $307 total
includes taxes & fees
Jul 28 - Jul 29
Hilton Garden Inn Rome Airport
Porch

Hotel Riu Plaza España

Hotel Riu Plaza España
4.0 star property
Madrid Centro
9.4 out of 10, Exceptional, (5,061 reviews)
"great location, great rooms we had a great trip ."
United States
Ever
The price is CA $255
CA $280 total
includes taxes & fees
Jul 19 - Jul 20
Hotel Riu Plaza España
Courtyard

Hôtel Saint Georges

Hôtel Saint Georges
4.0 star property
Nice City Centre
7.4 out of 10, Good, (937 reviews)
"Excellent location, clean room, spacious bathroom, friendly staff"
Canada
Monica
The price is CA $207
CA $239 total
includes taxes & fees
Jul 27 - Jul 28
Hôtel Saint Georges
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mediterranean Region.
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Avenida Catedral, 7 Barcelona
The price is CA $373 per night from Aug 12 to Aug 13
CA $373
CA $453 total
Aug 12 - Aug 13
includes taxes & fees
9.4/10 Exceptional! (1,856 reviews)
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Learn more about Mediterranean Region

During your stay in Mediterranean Region, you can discover things to see and do in the local area.

See all hotels in Mediterranean Region
A winding road through a mountainous landscape with the sun setting behind the hills.

Top Mediterranean Region Hotel Reviews

The Stanley

The Stanley

10/10 Excellent
"Great place to stay!! Staff was awesome and perfect location for hop off and on bus tour. Picks you up right in front of the hotel"
Kodi 3-night trip
Posted 3 hours ago
The Stanley

Find out more about Mediterranean Region

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Mediterranean Region are calling your name. Known for providing first-rate service in amazing locations, each of the Mediterranean Region 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Mediterranean Region. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Mediterranean Region, , neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Mediterranean Region hotels with 4 Stars provide everything you need to unwind in style.