Title: Fishing Vacations in Eastern South Dakota 2026 | Expedia.ca ![](https://images.trvl-media.com/place/6059512/766cb7b6-6b2a-453e-83e5-a56e7d2f54bd.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Eastern South Dakota Fishing Vacations ## Book a Hotel + Flight or Car together to unlock savings Photo by Sig - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Fishing Hotels in Eastern South Dakota ![Lewis and Clark Resort](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/a76b5f6a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lewis and Clark Resort 43496 Shore Drive Yankton SD - 2 hours drive from Denny Sanford Premier Center Book a stay at this beach hotel in Yankton. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lewis and Clark Recreation Area and Midway ... 8.8/10 Excellent! (284 reviews) Rooms are clean, no frills, place is quiet. Nicely priced. Way better than a hotel. Reviewed on Dec 9, 2025 [](https://expedia.ca/Vermillion-Hotels-Lewis-And-Clark-Resort.h11267995.Hotel-Information) ![Cabin on bluff of Big Sioux River with rushing waters of the Klondike Dam below.](https://images.trvl-media.com/lodging/20000000/19080000/19071300/19071255/a9bcf9df_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cabin on bluff of Big Sioux River with rushing waters of the Klondike Dam below. Larchwood IA - 44 min drive from Denny Sanford Premier Center Stay at this vacation home in Larchwood. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lake Alvin Recreation Area and Lake Alvin Beach ... 9.8/10 Exceptional! (184 reviews) Host was very prompt with replies to questions. Great location! Loved the view of the river from the hot tub. Nice short walk to the river bridge, beautiful.House had everything we needed, loved the large dining table. Worked perfect for out group of 7 women.Would love to stay here again! Reviewed on Nov 26, 2025 [](https://expedia.ca/Larchwood-Hotels-Cabin-On-Bluff-Of-Big-Sioux-River-With-Rushing-Waters-Of-The-Klondike-Dam-Below.h19071255.Hotel-Information) ![Comfort Inn Yankton SD](https://images.trvl-media.com/lodging/11000000/10450000/10440200/10440162/70f394ec_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn Yankton SD 611 W 23rd Street Yankton SD - 2 hours drive from Denny Sanford Premier Center Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ... 8.8/10 Excellent! (667 reviews) Nice place, comfortable Reviewed on Dec 13, 2025 [](https://expedia.ca/Vermillion-Hotels-Econo-Lodge.h10440162.Hotel-Information) [See all 901 properties in Eastern South Dakota](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6059501) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Eastern South Dakota ](https://expedia.ca/Cheap-Flights-To-Eastern-South-Dakota.d6059501.Travel-Guide-Flights)[ Eastern South Dakota Hotels ](https://expedia.ca/Eastern-South-Dakota-Hotels.d6059501.Travel-Guide-Hotels)[ Eastern South Dakota Vacation Rentals ](https://expedia.ca/Eastern-South-Dakota-Vacation-Rentals.d6059501.Travel-Guide-VacationRentals)[ Eastern South Dakota Car Rentals ](https://expedia.ca/Car-Rentals-In-Eastern-South-Dakota.d6059501.Car-Rental-Guide)[ Eastern South Dakota Vacations ](https://expedia.ca/Eastern-South-Dakota.d6059501.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app