Title: Adults Only Vacations in Southeast Missouri 2025/2026 | Expedia.ca

  

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# Southeast Missouri Adults Only Vacations

## Book a Hotel + Flight or Car together to unlock savings

Stay added

Flight added

Car

-   Economy
    
-   Premium economy
    
-   Business class
    
-   First class
    

Leaving from

Going to

Dates

Travellers

## Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

I only need accommodation for part of my trip

-   ## 
    
    Plan, book, travel with confidence
    

### 

Better together

Save up to CA $1,096 when you book a flight and hotel together\*

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Find the right fit

With over 300,000 hotels worldwide, it's easy to create a perfect package

### 

Rest easy

Plan, book, and manage your trip all in one place

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## More Vacations Ideas

[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Southeast Missouri Hotels](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Southeast Missouri Vacation Rentals](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacations](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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## Go further with the Expedia app

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Scan the QR code with your device camera and download our app

![QR code to download the app](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAMgAQAAAADzCzvFAAAFDklEQVR4Xu3bPXIbORBAYbAcKNwjzFF0NPBoPAqPsCEDlrDqH6AxmLG2ura8AfleYrLZwMeMpmyV9j9U1sGfCCQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVCCpJuRZljaZXstf7csH09altVvf+h7V9rfvjGrcDAICAmJtMgUBAVmQGs+aI82Of7aH/DFuVOTDFmI02t8FAgICIoHEaAQC4rvahyHnN540tjQ/OAJZAgEpICAeyBKI75bvr9hj+btf8q1b04/91u7yGASkgPTlAjICkccgICWLNLuxH5cbFZld3WogICAgfSkegtgDkE2mID8h0XS8yAf6fjS7xd7dxV7TQPYjEBAQCUQD2Y9AnrI9t9mu3/hhyO9HSzVuBjkZLdW4GeRktFTjZpCT0VKNm0FORks1bgY5GS3VuBnkZLRU4+YJOe9a5q/Y/lb0K/Ye+SmQBnIayBxIAzkNZO6VEf1VJj1e7MfZirT2GEi1rf0/MHsPebb1Zx4IiAdigYBEICBt3HgTRI4r4r9c7CNP3fng/CvIenAKBKSB6EEQEBAQa0KeshG7pWw20j51+Tgab8VHj/FyHReDjBHIWDvceDICGWuHG09GIGPtcOPJCGSsHW48GYGMtcONJ6P/gnzIYBw/fOzHaLhxUP74Fdc2EBAQEBAQkH9DtIc81t3rMtL8H5i9cHXL76p2TAJpIOM4iG35XdWOSSANZBwHsS2/q9ox6SWRZrvFvym3dpfH1V65yePdbvMb7/2tfI0v4upOgWggICAgICDedFA/lw+/pCTpp7csW2NLv3Vr12nrGIgGAjJtHQPRQECmrWOvipTiX57juNQ/vf1jX7pMW35Qtx594futjEBAQEBAQCSQ3h6pTW8scryUzeb6ga7HfUsKRL9i+5Ye9K1qjyQQEBAQEBCQ3yBtfFP2414g0i/b0lGzt6I3OlLGW6lxA4iOGggIiAcSN4DoqL0z8rSdjshxzY/raG5292/F3RFIAbEjINMIBEQDKSDy+v4n3LHro3u/8WJjHRXb0u/mnm6NQEBAQEBAqj0C0fZIbbr7qa9YtcWn90A0dUvZ+nM9qFtrIA0ExAMBWQJpIHbrxY+PkX7sa6uro81e01HpB/eBFBBbA7HXQEAikAIixyM/fl1cbUaKfez76GFW2d0FAgICIoGAgPRWJHZ9ei2KaOPGffHu9K3Iu9u/YZA5EBAQEB9JIHNvi6zpjeH68ZNv3aOP8coUSG/elkBAIpDevC2BgEQviZz0tI/q8386vtm16sqWjhS527sbgTSQYyAgIBJIe3vkaYciP67/l9qP77f8xjJtaVtcqoFoIHMgICAWiPbuSI1nzXev9n1aj/uN0kWGj/6sH7z15z99xtd4BmKBFBAQEBCr2plbf/4uiP44Wz+9BfGR3qjd+/Gvft2xacsDAQFZAxk7ICOQtTdHIh+NfKvZ3wS+/Ofgx4MgICDyCshxFwQE5Axpdlx7yKe3bkmX8a17TkdejTEICMiUjrwaYxAQkCkdeTXGr4tEjjRzP/v4R0TfCgiIBwICsgsEJIZ7ZN8m06s9/rTjm23p92n/m8BIXR3pwSkQEJAeSAPZBwLy5wJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZIKJBVIqtdB/gERxOSe5LzhzQAAAABJRU5ErkJggg==)